DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Prevent heavy periods exstream anxiety, depression, hair loss, back pain, sweats at night, struggling to get too sleep, feeling tired all the time, lack of motivation, mood swings(one minute fine next i'd lose my temper really easily, or cry over anything), stomach cramps, ex stream hunger pains and hungry all the time and craving foods. When I first got the injection, i started to feel nervous about everything, i't got so bad i could not attend college and had too quit. I was experiencing so many different things and had no idea what was happening to me, i felt powerless and as someone who had previously been out going and confident i became a shell of my old self. Previous to getting the injection i believed i had done research, i read the information given to me by my doctor and felt confident it wouldn't affect me too greatly as all i initially wanted was to be rid of my monthly nightmares. Not long after the intial first injection i attended the doctor about anxiety problems, i was nervous about everything and anything, being sick or diarrhea when i made plans to leave the house, pannick attacks and more ect. My initial worry was the injection had caused it but my doctor asured me that this was not the case and that they where not linked, i then started on tablets to 'help' with my anxiety, these did not work but i relyed on them because i felt i had no other choices. I then revisited the doctor about night sweats, these where unbearable for me and where disturbing my sleep nearly every night, and the nights i did sleep i still felt tired, drained and unactive the next day, atlhough i was hungry, craving certain foods, and nothing could stop my hunger. In the apointment my doctor assured myself and my mum that none of the symptoms where connected. For the last six months i've experienced so much that h F 17 6 months
1X AN		 9/25/2011
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 1  contraception Headaches, severe mood swings, cramping pains, severe tiredness, weight gain I would strongly recommend that everyone stay clear of this poison!!! Ruined my life, almost broke my relationship and my kids have had to live with a messed up mum. Not good!! F 29 6 months
1X M		 9/19/2011
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 1  horrible cramps and no pregnacy i have been bleeding since i got the shot im super mean mood swings hot flashes nausa it has been all bad i needed it because of cramps that would make me pass out and you could actully see move over my lower stomach but i have been bleeding for 6 months everyday im a total B**** i get sick to my stomach and i started feeling very depressed a weeks after i first got it but hey the cramps went away F 18 6 months
2X AN		 9/24/2011
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 1  Pregnancy prevention Depo shot has almost put me into a grave. After getting my second shot the might mare began. I started bleeding heavy that I had to go home earlier from work and miss work do to that. After on heavy bleeding week my period still didn't go away. I started having sharp pain in my whole abnomal area the pain was so intense that I coudnt get out of bad or walk and the heavy bleeding continued. I started feeling dizzy on top of that. So I finally called up my doctor and I explained the problem to him and he told me to go to the emergency room immediately. So I went to the emergency room and they said I lost to much blood after running tests. My hemoglobin was at 3.2. So I had to get blood transfusion done. They ruled out my heavy bleeding and was said that the lining of my uturus is to thick so my body kept shading the lining and that's why I have heavy bleeding and the depo shot was the cause of it. Please don't use depo I almost died from it. F 25 6 months
1X day		 5/26/2011
 1  Birth Control - Regulate Periods Severe stomach cramping and pain. Back aches and nausea. Side effects were similar to symptoms of endometriosis. Had a diagnostic laparoscopy at the due date for my 3rd shot and was all clear. I never went to get my shot while recovering from surgery, and as the medicine left my body. I felt better. Had surgery due to these side effects. Doctors never put it together. F 24 6 months
1X O		 6/6/2011
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 1   I bleed for 4 months lost wieght, received another shot and gained 20 pounds and I am short. Loss of sex drive. After the weight gain I stopped the shots. Had maybe 2 periods a year for 5 years. Totally messed me up. Dr.s called me a medical mystery. I am now 31 and can not get pregnant. This was not a well researched drug. We are the ginnie pigs. The side effects can be very devestating!!!! Also cysts that have ruptured. I stongly advise never take the risk with this unresearch birth control!! They should compensate the victims of this horrible DRUG. They take no accountablity for the side effects of depo. F 6 months
 11/18/2007
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 1  contraceptive continuous spotting, depression instead of not having periods I bled all of the time. ruined alot of bed clothes and really is not sexy at all. F 20 6 months
 11/16/2007
 1  convenient and more effective extreme anxiety, felt like i was crazy and at a total loss of control, very hostile, extreme stress, loss of interest in things I loved to do, fought constantly with my boyfriend and started fights for no reason at all and flipped out over the stupidest situations, short attention span DON'T TAKE THIS EVER! Go with the pills if my age and haven't had a child! They worked the best even though they 'aren't as effective!'... F 19 6 months
 3/23/2008
 1  contraceptive irregular bleeding, EXTREME PAIN during intercourse, vaginal dryness, migraines, insomnia, panic attacks, slight weight gain I've only been on this medication for 6 months and cannot wait until it's gone from my body. I wish I never took this stuff. Sex started out as being just uncomfortable as I couldn't become lubricated and was extremely dry... then that problem went away, except sex has become SO extremely painful for me. My vagina feels like it has open wounds and is ripping apart during sex, I've been to the doctor numerous times and they can't find anything wrong with me. Now I know it's Depo, and after reading all these reviews I can attribute my awful migraines that I've been getting everyday, random panic attacks, and insomnia... ALL to Depo. STAY AWAY FROM THIS MEDICATION. It should be taken off the market. Please email me if you want to talk about this more or have any questions. F 21 6 months
 4/28/2008
 1  prevent pregnancy LOSS OF SEX DRIVE- I don’t even want my bf near me MOODINESS everything and everyone annoys me LAZINESS- all I want to do is lay down, watch TV and sleep, and having an 18mon old this is hard I want to do stuff with him!! NO motivation!!! RAGE- out of nowhere! DEPRESSION- I just fall in and out of this SAD- just feel sad at times VAGINAL DRYNESS- I’ve never needed lube until now! JOINT ACHES- I feel as though I have arthritis! BACK ACHES- it’s unbearable STOMACH ACHES & CRAMPING- especially when the shot is due again I get really bad cramping, esp. after urinating to the point it makes me want to cry, its feels like your uterus is contracting when you are giving birth WEIGHT GAIN- none of my jeans fit, they are all tight, even though I have not been eating because: LOSS of APPETITE- I’m not hungry, then I am, then I’m not, then I am... its driving me Nuts!! Since taking the shot it has TRANSFORMED ME my boyfriend is the sweetest guy you will ever meet but yet I find ways to be mean to him, for NO REASON! I don’t know where it comes from and I CANT STOP the anger! everything irritates me, I have not felt the same since I have taken it, and it feels almost as if I need it now, last month I went to PP and told them my side effects and how I was having severe stomach pain and I wanted to know whether that was normal, they said that it was just because I needed the other dose to help with the pain, and I just wanted to be rid of the pain, and is why I decided to take the next shot, that was the second time, now again I have 2 weeks until my next shot is due and I am experiencing the same excruciating pain, it is almost unbearable, and it is especially worse right after urinating, it feels as though my uterus is contracting, and quickly after I spot blood. I’m afraid for my relationship with my boyfriend because to be honest I know F 23 6 months
 12/29/2008
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 1  birth control headaches, SEVERE depression, weight gain, moodiness, loss of sex drive, no energy i have only had 2 injections but it has had its effects already. i have gained about 30lbs in the past six months. i have had thoughts of suicide to the point of cutting my self. my boyfriend bless his soul has put up with me but i know im damaging our relationship with all the highs and lows i go through everyday. i had seizure out of no where and my dr. contributes it to the shot. i had bad knees before the shot and now they kill me ALL the time. and the arm i get my shot in hurts in the muscle to the point that i need heavy medication to take the edge off. WOULD NOT RECOMMEND THIS TO ANYONE!! F 19 6 months
 1/5/2009
 1  To prevent pregnancy WEIGHT Gain and very libido, moodiness This has been absolute worst thing ever. I only took 2 or 3 doses of the medicine and gained over 20lbs. I have dieted, worked out and nearly starved myself to death and cannot lose a pound. I have never had a problem losing weight and now I am just about ruined. If anyone has any suggestions about how to lost the post depo weight, please let me know. Also I have no sex drive at all. I feel like it's a job versus something for pleasure because I'm never in the mood. F 27 6 months
 3/6/2009
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 1  Birth control Weight-gain, extremely low sex drive, severe moodiness (especially close to when it starts to wear off) - very tired and depressed. I absolutely hate the depo. I took it to obviously keep from getting pregnant but this stuff works by making you not want sex at all. When I do have sex, it's as though i cant feel any sensation, it's horrible. Also, I am a very petite girl and this stuff has made me gain about 10 lbs and i hate that, i am not happy with the cravings i get for foods i dont even like... i feel like a pregnant person and i am not even pregnant! This pill makes my depression so much worse and my moodiness is so bad i dont know how my bf can stand me... i am very moody very depressed, feel like sleeping all the time - can barely get my school work done and go to work full time.. i was suppose to get my next shot 4 days ago. Guess what?!?! Hell no!!! I am never taking this shot ever again!! I want my body back, I want my energy back and I want my level headedness back and I cant wait for this shot to fully leave my system so i can get back to my life. I am absolutely annoyed by this shot having such a negat F 26 6 months
 3/11/2009
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 1  TAKEN ORAL PILL FOR 20 YEARS After first week bloating, acne and then cysts started forming under both arm pits. Over over the next 3 months continuous heavy bleeding. Extreme weight gain which looked like puffiness. The cysts became unbearable needing antibiotics. My first Depro injection 1995. I've always had a normal 28 day cycle. The injection was advised as a suitable replacement to the pill which I had taken for 20 years. The doctor was keen to use it saying side effects were rare. The adverse effects kicked in within a week. Bloatedness leading to weight gain. several cysts reoccurring under each armpit making any movement unbearably painfull. The periods did not cease and STILL HAVEN'T. I couldn't wait for the drug to leave my system but foolishly convinced by the GP the symptoms would pass if I kept with Depro so I allowed another toxic dose. The cysts got worse, the weight increased along with heavy dull aching periods constantly, plus deep aching lower back pain. I had 3 children plus a part time job to maintain at that time. Moving on I'm still bleeding continuously and suffer anaemia leading to extreme lethargy intermittantly. This constant bleeding definately affects my health. Osteosporosis was diagnosed at 41 with an early meno F 45 6 months
 2/8/2009
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 1  severe menstral pains BEWARE!! If you have a seizure disorder DO NOT TAKE THIS SHOT. My daughter was started on it with approval of her neurologist for her painful periods, she started having small breakthrough seizures and I kept questioning if it could be the shots, she had 3, but was reassured that it was not a SE, after the 3rd she had the worst seizure yet and ended up on a ventilator and didn't wake up for 5 days. There have been permanent effects from the seizure and we are still dealing with those. Please don't take if you have seizures!!! F 15 6 months
 1/26/2009
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 1  Extreme PMS WEIGHT GAIN & CELLULITE!!!!!!!!! I gained 30 lbs in six months & got cellulite in places I never imagined a person could get it!! I still can't get rid of the cellulite or all of the weight!! It's been several years and lots and lots of exercise, super spinning bike classes for just one thing. I always had the matabolism of a humming bird until I took this shot and when I talked to my doctor he said the shot would not cause weight gain. I guess he thought I had suddenly become a gluttonous pig that ate non-stop, but no, he knew it was the Depo, I wasn't sitting there stuffing my face while in his office. He must have been getting a kick back from the drug company to tell someone with that kind of sudden weight gain to keep taking what was causing it. Doctors take an oath to do no harm but that was obviously a joke to him. We all know too much weight is unhealthy. I'm not stupid!! I changed doctors!! This shot completely ruined my body forever!!!! If you would love to gain lots of weight and have lumpy, bumpy cot F 35 6 months
 2/16/2009
 1  birth control Severe depression, INTENSE ANGER, sudden weight gain, hair loss, decrease in sex-drive, dissatisfaction I would never recommend the shot to anyone, it's terrible. I can't wait until it leaves my system. F 20 6 months
 2/16/2009
 1  Birth Control Pain during intercourse, slight loss of libido My nurse, doctor and consultant were all surprised by this side effect, saying it was something they hadn't encountered before and initially tried to attribute it to lack of lubrication, although this was not the issue. Have also put a little weight on despite considerably improving diet and exercise regime. Having no periods was good, but lowering of mood, increase in sweating, body odour for the first time in my life was not worth it. Been off it for 6 months now and the primary symptom of pain during intercourse has not yet subsided. Hoping (really hoping!) it will go over the next 6-12 months. On a recent trip to the doctors I heard (with no names mentioned) another patient had had similar difficulties with her contraceptive that week - I was surprised as I had no idea these issues were so common, until reading this page. F 25 6 months
 6/17/2007
 1  to stop my periods i originally started the depo shot because i found out I had to have a cold knife conization on my uterus and my OB/GYN said i COULD NOT be on my monthly during it. GOSH, I would have rather taken the risk. Here I am, 6 months later, I haven't taken my shot since January and I now have no period (haven't had one since 10/06), I have pain after orgasm (when I actually want to have sex, which is never), my fiancee doesn't understand why he has to beg me to be intimate with him. Emotionally I want to but I'm scared of the pain. I had major depression and mood swings, also. F 25 6 months
 7/9/2007
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 1  Birth Control I was moody and cranky a lot of the time and those around me said I was almost unbearable. I am normally easy going and get along well with everyone. I also bled for a month straight in the third month both times I took it and had to get on birth control pills to stop my period. It may work for others, but i think it's awful and does not work well for me at all. I wonder if I may have had an allergic effect from it that induced the bleeding. F 26 6 months
 6/7/2007

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