DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 2  prevent pregancy I have been taking the depo shot for 7 years. I have experienced the weight gain, no periods, and mood swings. I have also had digestive problems. I have become sensitive to caffiene. From the depo shot? I don't know. But it was all of a sudden, and it started about 8 months ago. Doctors can't find anything wrong and told me to stop drinking coke so I did and when I do I get terrible stomach aches, chest pains, belching, which I never do, and have been diagnosed with acid reflux which I have never had in my life. The depo shot was great at first. No period. No babies. No worries. But now, I think I am going to stop recieving the shot to get back to normal, to get my life back. F 27 7 years
1X O		 10/1/2010
 2  contraceptipn depression, spotting. after 7 years of being on this injection I have finally come off it and feel like a different person. In fact I had forgotten what it felt like to feel normal. I hadn't realised how much this had altered my mood in such a negative way. F 26 7 years
 5/8/2007
 1  cancer prevention, DR reccomended severe leg cramps, gained 50 pounds in 7 years, no amount of excersise will reduce my weight. My diet is so healthy I have had my annual blood work and my cholestorol was only 152! I have been acting weird lately too, I cry at the drop of a hat, or I will want to break the first toy I see on the floor just because it is in my way. I do not want to act like this towards my kids' belongings! I tell them to respect their things and yet I want to smash them.. talk about mixed signals! Until this last dose I have been what I concider emotionally balanced, although now that I think back and have been a cranky wench about a week after each dose hmmm, but by no means evil streaks or crying fits. connection? I don't know but I am not taking any more chances. I just thought my weight gain was due to aging, I never knew about all the side effects until this week when as a last resort to relieve the joint pain and muscle cramps I looked into maybe it being from Depo. I have read a lot about hypothyroidism in postings, is this a side effect too? I now have hypothyroidism and it is barely controled with meds (I am at the highest dose of 2 meds legaly prescribed) After reading this post site I will not be getting another shot right after x-mas. I love not having my monthly, but it is not worth my pain and suffering. No sex drive at all, nil, nada.In fact, I have not had sex in 7 years (how abnormal is that) just not interested enough to go out and find a good man after my low sex drive drove a wedge btween me and my boyfriend that could not be repaired, he thought I just didn't care about satisfying him any more. Women in my family have history of tumors and overian cysts, I was told that this med would greatly reduce that chance for me, my DR s F 33 7 years
 12/1/2008
 1  contraceptive loss of scalp hair, increased facial hair, ibs, anxiety,agoraphobia, abdominal pain, migraines, weight gain, acne, depression Please contact me if you know when the side effects will end i stopped taking the shot in December If someone would have told me what i know now i never would have taken this shit. i was a healthy 17 yr old when i started. i'm now 24 and i have problems leaving the house because i feel like i'm going to lose my bowels. i had a brief stint of agoraphobia and almost didn't graduate from college because of it F 24 7 years
 5/22/2007
 1  heavy periods I now have a pituitary tumor and cushings All the weight gain over 100 lbs. Lost job due to being sick F 41 7 years
150mg		 1/27/2015
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 1  Birth Control Weight gain, vaginal dryness, no sex drive, painful intercourse, bleeding after intercourse, irregular bleeding and spotting, intense cramping after orgasm, random irregular bouts of severe cramping, tiredness all the time, lack of energy or interest in anything, hair loss, bloating, IBS, frequent urination, emotional and moody, paranoid, depression, anxiety, sore boobs, bloating and gas, joints and muscles ache, occasional headaches, bad acne, anger problems, and possibly other things I haven't noticed yet. I have been on the Depo since I was 18 and was not informed of any of the side effects at all. Most of the side effects I have experienced didn't start up until a few years after I first started taking it. I'm tired of being in constant pain and discomfort and did not continue with my current shot. I instead started on Lybrel bc pill which is the first and only no period pill. I love not having a period and can and will deal with occasional spotting but hope all of my other bad symptoms will go away. Please research before going on the shot it's horrible and I fear will take forever to leave my system. I have also heard that the shot can make women more susceptible to STD's so be careful, also of the bone loss issue. F 25 7 years
4x a year 4X O		 4/5/2010
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 1  Birth Control While on the shot; major weight gain, loss of period, moodiness, constantly sick, nausea, vomiting, migrane headaches, could not hold food down, joint pain, muscle pain, blurry vision, depression, always tired, and could never get out of bed, Sometime, I would spend days in bed because I was constantly very tied. Eventually, this drug caused me to have a stroke and be a in coma and almost lose my life. After I discontinued; hormonal imbalance, irregular and very heavy periods, trouble taking the weight off, and some muscle pain. When I was 18 years old, my mother through me out of the house because I did poorly in an exam, dropped the course, and change majors. I had no place to go. So I stayed with a guy who I was dating at the time. After a few months, I fell pregnant and he kicked me out. Then I called my great aunt, who called my mother and told her to take me back in and she did. Then I told my mother I was pregnant. In order for be allowed to come home, I had to terminate the pregnancy, agree to never see this guy again, get a part-time job, and go on the depo shot. I agreed because I wanted to get my degree and needed her help. After the first shot, I was starting to feel tired, gained a little weight and my periods became irregular. But after the secong shot, was when the side effects was in full force. I when from being this very athletic, skinny and energetic teenager, to feeling like I was 90 years old. I was on the track team. People thought I was going to be in the Olympics. After the second shot, I became tired, fat, sick all the time and in constant pain. I went to different doctors, trying to find out what was wrong. That was when I found out it was the depo. The next shot was due and I did not go. When my mother found out, she got very angry and threw me out again. However, she let me come home the next day but I had to go to the clinic with her and get the shot. I suffered alot because from then on, my mother would drag me to the clinic to get the shot against my will. F 32 7 years
1X O		 3/6/2010
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 1  Birth control Gall bladder failure, extreme estrogen suppression, lack of period I took depo because of the ease. I have trouble with daily pills. But you should not be on it for more than a couple of years at a time or you end up in surgery and feeling like you are going through menopause early like I did. Be careful. F 34 7 years
1X O		 12/27/2012
 1  Birth Control Let me tell all that feel this is a wonder drug. I thought it was too. Now look at the huge list of side effects I have. I'm warning everyone now to get off it now while you can. It can destroy your life. Maybe everyone is different but this drug did truely ruin mine. Here's my list! Diagnosed severe depression, bloating, weight gain of 80 POUNDS, fatigue, memory issues, lack of concentration, anxiety, smelly arm pits (even after the shower), severe acne, no periods even 5 years after being off the drug, no sex drive, chronic vaginal infections, chronic illnesses and chronic migraines. My doctors just love me. THE WORST MEDICATION EVER INVENTED... There are now lots of lawsuits out there about this drug. F 29 7 years
 4/8/2006
 1  Birth Control Weight gain, nausea, depression I took my last shot 4 months ago. I was on it for almost 8 years. I thought / and I was told that side effects would go away after a few shots. I was fine the first few years but found I was getting weepy or hungry before the shot was due. I went off for a year and lost a lot of weight. I then got back on thinking that with diet and exercise I would be fine. I was wrong and gained about 1lb a month for the next 3 years. Now that I am off I am experiencing what I can only assume is withdrawl. I have had nausea all day for almost a month, my breasts are sore. I feel like I am stuck in first trimester pregnancy. I have noticed that even with all of this I am not depressed though. So in summary it was good for a while, but I would not suggest for long term - also I would suggest people to really pay attention to how they feel when on the shot. The depression really snuck up on me. F 26 7 years
 10/23/2005
 1  QUESTION CAN SOMEONE PLEASE POST WHAT HAPPENED AFTER THEY STOPPED THE SHOT!!???? CAN SOMEONE PLEASE POST WHAT HAPPENED AFTER THEY STOPPED THE SHOT!!???? ESPECIALLY THOSE WHO SUFFERED SIDE EFFECTS... ARE YOU BETTER? HOW LONG DID IT TAKE BEFORE YOU FELT BETTER? HOW LONG BEFORE A PERIOD? AND SO ON..... I HAVE ANOTHER POSTING ON HERE W MY EMAIL I WAS DUE FOR THE SHOT JULY 25, 2005 AND DID NOT GET IT. I ALONG WITH OTHER WOMEN WHO EMAILED ME WOULD LIKE TO KNOW THE ANSWERS TO THE ABOVE QUESTIONS AND MORE...THANK YOU!!!! F 29 7 years
 8/1/2005
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 1  birth control Crippling Migraines,muscle tension neck and shouldrs. Migraines stopped after coming off but then the rest started. Drug should be banned, irresponsible drug company in my opinion. Not enough known about serious side effects. I thought at first it was a wonder drug(what women does want a period?), but eventually i started to drawn my own conclusions about the serious effects i was noticing on my body. Doctors will tell you nothing about long term and may misdiagnose side effects of this drug.This drug does not have adequate labelling. Before starting i had very normal periods and a pregnancy. After coming off after 7yrs i bled non-stop for 7mnths and now have cysts on my ovaries and no period, possibly Polystic ovarian syndrome. I completely blame depo for the problems i'm now facing, and wonder after 3 yrs of being off it if by body will be able to get back to normal. There should be a class action case against the drug company for not making women aware of the serious long term affects of this drug which have never been stated. F 27 7 years
 12/22/2004
 1  To control lengthy periods Absolutely ZERO sex drive, depressed, terrible mood swings, nausea, acne, HOT FLASHES. At the beginning I took this shot b/c I was having periods that lasted 3 wks a month and they were VERY heavy. I stopped having periods all together and thought it was great. I am now 26, the gynocologist told me that my body had ZERO estrogen b/c of the depo shot, so it was like I was going thru menopause. Sex is very uncomfortable while on the shot since your body stops producing estrogen, you cannot "lubricate" on your own. My new gynocologist immediately took me off the shot and was shocked that I was on it for so long. She said, "hopefully your ovaries will start workin again... we'll have to keep running tests". So now, I'm having to go back to the gyno on a monthly basis to get blood work done to see if my estrogen levels are going back up and to see if my ovaries will "work again". I was shocked and saddened by this b/c I do want to have children some day. I have been off the shot for almost 3 months and still have not had a period. My gynocologist F 26 7 years
 10/13/2008
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 1  prevent pregnancy i have gained about 50 pd with in first 2 years on it, i have headaches migranes, always moody, no sex drive what so ever, terrible bone pain i just recently quiet taking it after 7 years F 23 7 years
 6/20/2004
 5  cramping, heavy periods, bc slight weight gain The negative side effects were indistinguishable, and it ended my monthly torture sessions. I had no problem getting pregnant with my first child after using it for 6 years, but my periods became terribly prolonged after my second stoppage. I look forward to going back to it. F 29 7.5 years
 5/4/2006
 4  birth control some hair growth and weight gain I have been taking depo for many years and it is an effective form of bc, there are some pesky side effects that I have experienced but nothing that can't be fixed. My mother took it once and had a freak out and now is cursing it up and down but she has had depression all her life and it specifically says not to use it if you are affected with that ailment. I had horrible horrible keep u up at night cramps with periods that contained a lot of blood clots. I still get spotting during the time that I am supposed to have my period but that goes away with another dose. as far as some women are concerned letes look at body mass as an example. the dose is the same for all women big or small. I think that perhaps alot of the problems that are associated with depo have to do with how much u weigh. it really makes perfect sense. ur body can react differently to the amount of alcohol intake with reagrd to size correct? so why isn't the same with a drug such as depo. 1ml for every womon would be F 25 7.5 years
 4/5/2006
 5  birth control I love the shot. No weight gain. Besides the year I was off of it to have my child I have been on this for 8 years. Normal bone scans. No issues. F 30 8 years
 10/28/2012
 5  birth control spotting for duration of first shot. mild hot flashes. i absolutely love this shot! started taking it about nine years ago. have it listed as eight but thats because i got off of it to conceive and birth my daughter then resumed the shot. no weight gain. in fact after dieting (which is never did before) i have lost 40 pounds and kept it off. couldnt recommend this shot more. i know everyone reacts differently giving it a chance wont hurt though! F 28 8 years
1X day		 12/1/2012
 5  Painful periods, Dr. reccommended 10 lbs gained initially, then lost them!! Price has increased to $200 per injection. Thank you Depo! My cycle had made me sick for my entire life, and after my doc started me on it, life for me began!! No PMS, no more acne, sex is great, and I feel great! My doc explained this drug is not reccomended for teens due to the drastic hormone shifts that occur during that time of life, and that bone density issues can be combatted with weight training and good nutrition. My thyroid and bone density tests have been perfect! I'll take this drug for as long as I can! F 30 8 years
 7/24/2005
 5  control heavy periods weight gain i was on this medication for over 5 years and it was fantastic -no periods, no mood swing, no painful swollen breasts. Went off due to concerns about my weight ( am about 20kg overweight) and skin sensitivity from the steroids in depo. am SERIOUSLY considering going back on it, my breasts are SO SORE AND SWOLLEN I can barely move !! F 36 8 years
 10/14/2007

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