DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth control Extremely long-lasting period!!! Mood-swings, loss of sex drive, weight-gain! I have had 3 shots so far. At first I was satisfied with it, but after about a month I took my fist shot I had my period for 6 weeks. My doctor said its because I had stopped breastfeeding, so I thought that made sense. 2 days after I got my third shot, here comes my period again, 24 days and still going!!!! I wish I knew about these side effects, because they seem to be so common. Also, I lost my sex drive completely! F 23 7 months
 12/29/2008
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 5  Heavy bleeding The only side effect I have noticed is night sweats. I love the shot it helped my situation a great deal F 29 8 months
Idk		 5/17/2012
 5  do not want kids. im young. I havent had any crazy problems with the depo. I get moody at least twice a week but who knows with that...im a woman. I know woman who arent on it and they are very very moody even worse than i get. I really think its just a girl thing. Anyways, i would recommend it. I think i just depends on how your body works as to how you react to it. F 19 8 months
1X day		 10/18/2011
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 5  pregnancy prevention None...in fact, I feel great, have lost 7 pounds, and have no side effects! Depo has worked reallly well for me, despite many bad reviews F 26 8 months
1X AN		 10/14/2010
 4  Prevent pregnancy. Less periods. A lot of vaginal discharge on my 8th month. I had very light periods on my 7 months of having the depo shot. I was scared to have one of those longer periods because my friend had said she bled a lot for a couple weeks. I think I'm starting to experience it since I've had the period for a week and a half now and it's still strong. I do recommend this shot but you have to be open-minded once you have a longer period and it's strong. Be prepared for it. F 20 8 months
1X day		 3/31/2011
 4  birth control no period, no spotting, derpression, mood swings, slight weight loss, slight increase in acne, extreme decrease in sex drive initially (the first ten days on depo) i bled enormously. it was gross, and it scared me. once it stopped, i felt incredible. i began to lose weight. had a more than healthy sex drive ;) and no side effects... approx two months after i started, up thru now: i have had a bit of acne (which i never had an acne problem, so a pimple here and there was worth not having my period). i also noticed a very strong increase in mood swings, depression, and the death of my sex drive. although it is great to not have my period, im thinking of stopping. the depression and mood swings have intefered too much with my life and my work. F 20 8 months
 1/31/2005
 3  Couldn't remember to take pill. I am currently on the shot. I am sexually active. I've been on the shot since April and all of a sudden I started having light spotting and very weird cravings! Is this normal? F 18 8 months
Unknown		 12/10/2013
 3  birth control i am always tired no matter how much sleep i get. I usually feel a dull crampy ache in lower abdomin but its worse for about a week after the shot. i do not get a period which concerns me. i love that it keeps me from getting pregnant and i dont have to worry ab surgery or taking a pill everyday. however, the negative side effects are far greater. if you have other options, use them. with every shot i feel worse. discuss implenon with my doctor currently. F 30 8 months
60 mg 1X O		 3/8/2012
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 3  SIMPLE birth control Constant spotting, severely decreased sex drive, increased appetite, and possibly mood swings (I am a girl!). I've only been using depo provera for 7-8 months, so I'm hanging in there for a few more shots... but this spotting has got to stop! I don't have menstrual CYCLES anymore, just really light bleeding EVERY DAY. I'd stop right away because I hate bleeding during sex, but I barely have a sex drive from the shot anyway. I only like and use Depo because it is so incredibly simple. F 18 8 months
 11/20/2006
 2  birth control, PCOS Extreme hunger, mild weight gain, acne, spotting to mild bleeding for an extended period of time (longer than a week) For the first couple of shots things weren't bad at all... coming up to the third shot, I started having major food cravings about a week before the shot and this went on about a week or so after getting the shot. Once that stopped, I began to start spotting, which I hadn't for the last 6 months, then it just kept coming more like a mild to moderate period and so far it has lasted 10-11 days without stopping. I also started to experience some minor face/body acne and some increase in facial hair growth. Don't know if all of this is due to the shot, but the non-stop bleeding, cramping and back pain is horrible. Needless to say, I will be looking for something else when this wears off. F 35 8 months
1 shot 1X O		 10/28/2010
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 2  Prevent Pregnancy Headaches the first 5 months but they have decreased. Low libido. My husband would say I was very irritable and short sometimes. Irregular bleeding and Vaginal Odor. I wanted to comment on the Vaginal odor because I have read many comments but I didn't find someone who had this same side effect. I did not have any bleeding after my first shot. I had my second last month and i have been spotting for almost 3 weeks. Since this spotting started I have noticed, as well as my husband, this embarrassing odor. For the most part I only notice this smell during intercourse. I hope it goes away when the spotting stops but it's so embarrassing that I am not going to have the third shot and will try something different! F 38 8 months
1X O		 8/5/2010
 2  Prevent pregnancy Awful. I've had panic attacks, been through depression, I've had stomach problems (diarrhea almost every day). Super moody all the time. Always tired. Haven't had period in 6 months though, so that's a plus. Other than that, not even worth it. I promise. I plan on not getting my next shot hoping The symptoms won't continue. F 17 8 months
 4/8/2015
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 2  to manage heavy periods constant spotting is my main issue...i have a fibroid that has caused heavy periods....tried to have it removed and the doctor ended up damaging my colon!! supposedly my only alternative is to have a hysterectomy but I've been told that I will most likely have more damage done to my colon due to adheasions from the first surgery. My doc recommended trying depo for a year to try and stop my periods....so far it has not worked. I am trying to hang in there for a full year to see if my periods will eventually stop otherwise I guess I'll be bleeding until i hit menopause. Hearing so many terrible stories about depo is scary but I'm hoping that things will eventually settle down since there do seem to be some people that do well on it. As far as other side effects go, I do have depression and lots of anxiety but I had that before I started depo so I'm not sure I can completely blame it on the shot. F 40 8 months
 6/9/2009
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 2  Prevent pregnancy & control period Weight gain, mood swings, more hungry/increased appetite, fatigue, laziness, depression I absolutely love the fact that on depo I don't have periods or when I do, they're very light. But the side effects are just not worth it. Thinking about switching to Nexplanon... F 18 8 months
 5/13/2016
 1  To prevent pregnancy Anxiety, hair thinning, panic attacks, depression, fatigue, emotional all the time, trouble switching off, bad skin.. the list goes on Do not take this form of contraception!!! Awful as so many others have already said. I hope I don’t feel like this forever as I had my last shot back in May and I feel worse than ever now I’ve come off it! Its affected my work and relationship! It did the job but really not worth it for the side affects. I will not be using any hormonal forms of contraception again, it’s put me off it completely and I don’t agree with it! I’m sure it works for some but I can quite clearly see here from the other reviews it’s definitely more negative! F 27 8 months
 11/7/2019
 1  Birth control severe depression, tiredness, mood swings,irritability, headaches, migraines, leg cramps, stomach pains, loss of sex drive First month on it I was sick a lot, but the next 3 months were really good. No side effects at all. By the 4th month, I suddenly became depressed and experiencing frequent migraines. Depression & headaches got worse, started experiencing more symptoms. I'm tired all the time, I'm in therapy for anxiety/depression, I'm just not happy anymore. I seem to have a lot of seemingly random symptoms, different kinds of stomach pains, constant feeling of unwell, I cant concentrate, I get very mad over the slightest things. I've been spotting almost everyday for a month now, now there's lingering abdominal cramps. Before this, I was in very good health. Now I'm just not myself. Its terrible feeling sick all the time. What did I do to myself? F 31 8 months
 8/1/2009
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 1  to regulate my menstrual. I can't stop bleeding! I can't remember the last time I haven't bled. F 8 months
 7/15/2013
 1  Irregular periods Headaches, nausea, panic attacks, anxiety, depression, extreme mood swings. This is by far the worst method of birth control. Most of all your stories break me down to a tee.. I started depo at 17 years old, got the first two shots and couldnt handle it. I gained alot of weight, had extreme depression, thoughts of suicide, major panic attacks. When i was mad it was almost impossible to make me feel level again. After getting off depo, which was the worst thing ever, i also had my period for 2+ months, and was extremely sick for years, and still am, and i believe that it is caused by depo. its been 7 and a half years now, . I have had problems ever since. I DONT RECOMMEND THIS DRUG TO ANYONE. F 25 8 months
1X AN		 1/25/2011
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 1  Birth Control Weight gain, Lowered libido, headaches, breast tenderness, muscle soreness, irritability, major blood clots I would not recommend this shot to anyone. I know with me I gained 45lbs during the time I took this shot. I would say may 10lbs was of my own doing because I could not control my hunger but the rest of it being from that shot. I have been holding out on my husband because I just feel no need fo sex which is odd. I have major headaches at least 3 times a week. Breast tenderness and I always feel sore and very very irritable like I wanna punch my husband in the face for no reason.. And major blood clots which made me think I was having a miscarriage. Dr's seem to think that its just me. But I went on diet and I work out 5 days a week. Hell Im in the military and am on verge of being put out just because I gained this weigh on top of other issues and I feel its making it hard for me to get my run to where it needs to be. DO NOT TAKE THIS ESPECIALLY IF YOU ARE SENSITIVE TO ANY MEDS. Ive been off this med for about a yr now and have been excercising regularly and eating more healthy and still have yet to loose this added weight. F 21 8 months
Normal Dos 1X AN		 5/20/2011
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 1  Birth Control Loss of sex drive, irritablitly, extream mood swings, spotting, depression, unhappiness with life in general, anger issues. weight gain, headaches, tired all the time (not sure if depo is the cause), back aches (again not sure if this is the cause). oily skin, feel hot all the time. I really hate depo. it does not work for me. i am so moody and cranky all the time. i feel like i want to bite peoples heads off and all i want to do is cry bc i feel so bad about myself. i feel really depressed and i start fights with my husband over everything and i was not like this before. i am getting off of it ASAP. F 29 8 months
 9/16/2004
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