DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  migraines due to hormones on menses heavy spotting for 4 months on depro for 4 months,I don't dare not wear a panty liner, severe depression, night sweats, loss of libido, aching joints in knees and elbows I went on depro to prevent my migranines (dr's suggestion). It did stop the migraines, I did get headaches but nothing close to the severe migraines I suffered monthly for 20 years. However, the depression started, night sweats and aching knees and elbows. Complete loss of libido. Feeling of being in a "black hole, void, like nothing matters" I am definitely going off depro, and will take back the migraines instead of this hopelessness I am expreiencing. Have the best husband, who is understanding and patience with me at this time in my life. e-mail me if you want more details. F 49 4 months
 8/28/2007
 1  Treatment of Miscarriage I was given Depo Provera after receiving 6 pints of blood after a miscarriage. The physician said it would help "regulate my hormones," I received the shot 4 months ago and have been bleeding non-stop ever since. This shot was administered while I was lying in a hospital bed and very vulnerable after having nearly bled to death. The Dr. offered no voluntary information regarding side effects of this drug, and in my weakened condition I was unable to ask the questions I normally would about medications. I honestly feel that this drug has ruined my life. I have gained 20 pounds, my hair is falling out, I have no energy, excessive bleeding, bloating and must own stock in Kotex by now. I particularly like it when I go to this Dr. and she asks "when was your last period?" I would love to give this Dr. a shot of Depo Provera! F 40 4 months
 8/16/2007
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 1  birth control weight gain, severe mood swings/psychosis, acne, gross brown/black spotting, brittle nails, crappy hair, hip pain, leg pain, back pain ok. i got on this shot bc i had taken it years back and it was ok for me, but this time it was pure hell. after a week or shoulder and neck stiffness i started getting moody and noticed slight weight gain. periods vanished and were replaced with some funky brownish black spotting that has been almost contstant since i got the shot (4 months ago) i became even more moody. like ending relationships randomly with ppl, crying, super anger, suicidal thoughts..just BAD depression. the worst ive ever felt in my life. i weighed 115 before the shot, im now about 140. this drug is BAD. i dont even see how it is still given to women. please do not take this crap. just after one shot and it screwed me up this bad. BAD STUFF. F 27 4 months
 2/5/2009
 1  I have severe endometriosis For the first 2 months or so I felt completely fine. The only problem I had was spotting and my doctor said that was normal and would go away after 3 months. Around the 3rd month I started to feel completely different! I started to feel depressed, cry over EVERYTHING, headaches, LOSS OF SEX DRIVE, extreme pain during sex ontop of the pain I already feel from having endometriosis, vaginal dryness, BAD mood swings, starting to slowly gain weight, and feeling hungry more often. I've been on this shot for 4 months now and I feel like a completely different person! My boyfriend has even noticed I've been different! AND my spotting didn't stop after the 3 months! It's been 4 almost 5 months and I am still spotting...its really gross! I am going off this shot! It's horrible!!!!!!!!!! I get annoyed so easily or I'm super emotional and I cry over anything...I feel like an emotional rollercoaster...happy for a min angry the next then I'm crying! I CAN'T WAIT TO GET OFF THIS SHOT AND FEEL NORMAL AGAIN!! I hope anyone who is thinking about going on this shot reviews it first! :( F 19 4 months
 2/20/2009
 1  Treatment for fibroids Insomnia, increased appetite, irritability, increased bleeding, backaches I had three shots in a three month period, per my doctor's recommendation. I haven't had a decent night's sleep without the aid of medication since December and I've been bleeding since January 23rd. I want this crap out of my system!! F 40 4 months
 3/9/2009
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 1  Birth Control Back Pain,extreme irritability, psychotic depression, intrusive thoughts of suicide, mood swings, fatigue, EXTREMLY Oily Scalp, So bad I want to shave my hair, I tried dying my hair..Changing Shampoo's..This has never happened to me before. I know it is because of Depo. I will be switching back to the Pill F 23 4 months
 12/4/2008
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 1  birth control uncontrollable appetite, migraines, fatigue, mood swings I am going back to the pill in January. I've had two injections of Depo and while it's great to prevent pregnancy, it makes me an absolute mess. Find another birth control method. This one isn't worth it. F 19 4 months
 12/1/2008
 1  didn't want to fall pregnant again mood swings, anxiety, nausea, pain in injection site & no periods. I have actually only had 2 Depo shots and it's played havoc with my body. Lately I've just been constantly wanting to cry or shout at everyone/thing. I can't stand the fact it's turning me into some sort of emotional train wreck. It's horrible. And it's heartbreaking putting my boyfriend through what he's going through with me just now. I only started with this after an unwanted pregnancy but I don't think I'll be continuing with it due to this. Avoid at all costs. If anyone has any tips on how to control these moodswings can you please email me? Thanks. F 21 4 months
 1/10/2009
 1  Birth Control Daily headache, dizziness, depression, anxiety, fatigue, mood swings, irritability, nausea, loss of sex-drive, weight issues. I could not figure out what was wrong with me. I'd had the Depo shot prior to having my son, for about a year with no complications. I also have a thyroid disorder, and have had seasonal depression (Nov-Mar) for years, but this was entirely different. Only until I started reading these comments did it begin making sense. The headaches are unbearable and difficult with a six-month-old. I'm constantly down and unmotivated. And I haven't GAINED weight because I've been working extremely hard to lose weight, but to no avail, this prevents me from losing anything! It's a real gamble to take this shot, because I would have reccomended it before, but just the CHANCE of it doing to others what it's done to me is enough reason to STEER CLEAR. I'm not getting it again, and I'm going to hope it will clear itself from my body and the side effects will go away, because it's made my life hell. F 26 4 months
 2/13/2008
 1  birth control migraine, weight gain, SEVERE DEPRESSION, joint pain, dizziness, anger, mood swings (like I was constantly PMSing), insomnia, RUINING MY MARRIAGE, chronic exhaustion, month-long periods I would never ever recommend this to anyone. I wasn't given any information from my dr except that I wouldn't get pregnant, wouldn't have a period, and wouldn't have to remember taking a pill. It sounded ideal, but after a month of my first shot, I had heavy bleeding for a month. I called my dr and he said it was normal and it wouldn't happen with the second shot, but same thing happened. Still have 1 1/2 months left before I get another shot, but won't do it bc of the severe depression it's causing. Have 3 little kids and is starting to affect them and my marriage. My husband won't come near me in bed, and my kids ask me constantly if I'm ok. DON'T TAKE THIS DRUG!!! F 27 4 months
 1/25/2008
 1  birth control excessive bleeding, PAIN during sex, loss of sex drive or libido, skin sensitivity, depression. I've been on it for alittle more than four months now and the whole time I have experienced bleeding and spotting. There has not been one day that I have gone without bleeding. It never gets to heavy but is constantly there. I have had depression for about 4 or 5 years now and this shot did not help whatsoever with it. However, the most aggrivating side effect so far is definitly the EXTREME pain I feel after about ten minutes of less of sex. There are even sometimes that I can't even have sex because the moment my boyfriends penis is inside of me it feels like my muscles cramp up and I get almost a raw sensation. I used to be a freak in bed and now that my libido has decreased INTENSElY, I don't have urges like I used to. This has been detrimental to my relationship sexually with my boyfriend. But above all, I am just plain out PISSED that I went to my doctor, described the pains I was getting, and told me it had nothing to do with the shot. I had a perfectly fine time having sex before this. I guess I should have just researched more about this "poison" of a shot before I went ahead and took it. I just hope someone reads this in their researching and learns from it at least. Who knows, some girls do fine with the shot, but from what I've been through and what I've read in other sites an blogs- there are alot of women out there who are just as PISSED as me. F 19 4 months
 4/5/2009
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 1  to control bleeding I have to buy new clothes every couple of weeks because my weight gain is so rapid; about 2-4 lbs every two weeks. I've gained about 20 pounds in total. By the end of the day, I'm so bloated that I can't get even baggy clothes off. I suddenly have acne all over my face and I've always had excellent skin. I have no interest in sex and it has severely worsened my depression. Lastly, in the first eight weeks after my first shot, I was fine for two and bled for six weeks: I spent $200 on tampons in that time period. I had surgery for endometriosis and went on the shot after the surgery failed to control my bleeding. I would rather bleed and have pain than go through this-the weight gain is disgusting. Most people gain about 10 lbs in the first year; I gained that in about a month. F 23 4 months
 8/11/2008
 1  Prevent Pregnancy Weight gain, moodiness, low sex drive I had an IUD for 8 years and loved it. Then I got pregnant with the IUD. It remained until the baby was born and everything turned out fine. 6 weeks after her birth, I went to the Dr. to get a new form of BC. I got DEPO. I was not told of these side effects when I had the first injection. The first few weeks I was really tense and sensitive. Now 4 months later, I have gained most of the weight back, almost to my pregnancy weight (within 10 lbs) and have not been too interested in sex. I went to the Dr. today to see what other forms were good for me an he told me of these side effects (different Dr. in the office). UGH! At least I know why I cannot lost he weight. He said the effects can last 6-8 months but you are supposed to have the shot every 3 months as a guarantee. I am going for a tubal! F 37 4 months
 3/16/2009
 1  birth control Loss of sex drive, painful intercourse, leg cramps, fatigue, spotting for 2 weeks after injection, spotting after intercourse I've gotten two Depo injections, and I WON'T be having another one! Reading all of these reviews makes me feel somewhat better; I thought it was just me. Obviously, it's not! M 37 4 months
 9/24/2009
 1  Birth Control Non-stop bleeding, heavy bleeding, extreme weight gain The worst thing I've every taken. I wish I had never taken this drug. My period was messed up for over a year and I gained a lot of weight. I gained 20 pounds in the first 3 months. When I tried to exercise I would bleed even worse, passing large clots of blood. F 31 4 months
1X O		 6/30/2015
 1  to build my blood up / I'm anemic Headaches, loss of sex drive, mood swings I took my first shot in September of 09, I have had light bleeding every since. I still had a period each month also. This has been a horrible experience and I will not take it again or recommend it to anyone. F 40 4 months
 1/14/2010
 1  contraception extreme tiredness/lack of motivation, irritibility, suicidal thoughts, feelings of low self worth,constant bleeding, mood swings, not knowing who i am or what i want, anxiety and panic attacks which havnt been present for years, change in bowel habit,lost 1/2 a stone in a week...and then gained almost a stone the next week and half, heartburn, indigestion,bloating, heart palpitations...and on and on in the 1st 2 weeks i was extremely moody and felt suicidal up to twice a day...didnt know wether i wanted to be with my oartner..and there was no apparent reason for this, sex drive was extremely low in the 1st month, diarhea in the 1st month, bleeding started just before the 2nd injection was due, i thought it was slightly longer than usual...but didnt think it would continue with the 2nd injection...about 30 days and counting. with the 2nd injection came increased anxiety, irritibility and a huge panic attack along with smaller 1s. Since the start of the injection i have been sleeping a hell of alot , have had bloating, indigestion and heartburn...none of which i have ever had before. The suicidal feelings made me leave my mediaction in the hands of my partner..scared to have it with me. Scared of socialising...and before this injection i had been better for 2 or more years. The acid,constipation etc and weight gain made me feel so pregnant...i was paranoid non stop...i wouldnt recommend this to anyone....research and dont make the mistake i did..i feel like im falling apart... F 20 4 months
 1/4/2010
 1  control heavy periods severe acne, hair loss, weight gain, extreme breakthrough bleeding, period everyday for 4 months do not get this shot! I have lost 4 months of my life and listened to my dr and went in for the second shot in hopes that my body will acclimate to it!I have been bleeding/spotting for 4 months! of course you wont get pregnant , you cant have sex if you are bleeding this bad!once the shot is in your body there is nothing you can do, at all!I have lost so much hair that i may have to get hair growth meds!!I never had acne before in my life and now my forehead and back are COVERED! THis shot is horrible and should be removed from the market! F 33 4 months
 1/24/2010
 1  to stop heavy periods & cramps continuous bleeding, hot flashes, weight gain, bloating, mood swings, no sex drive, depression I got the Depo shot in Sept '09 & has had a period everyday since. Got married the next month, October, and still had heavy bleeding. How disappointing is that to have your period on your honeymoon?!! My sex drive has pretty much disappeared. I feel so guilty b/c I cant even please my hubby at times because I feel fat & ugly. When I look in the mirror, I no longer see myself. Went back to the doctor in december & he stated it's normal to have bleeding for 3 months & getting the 2nd shot should lighten up or stop. FALSE!!! I regret ever getting the shot again in december. This is January 2010 & haven't gone one day without having a period. In 4 months, I've gained 28 lbs!!! I even exercised & still put on weight. It's really upsetting to go in your closet to put on an outfit & nothing fits. I was a size 10 & now I'm a size 14. I'll never get the shot again. For anyone reading this, please DO NOT get the shot!!! F 28 4 months
 1/24/2010
 1  My period is horrible Since I have been on depo I've bled.. in January it would make 6 months of bleeding with this blood come a stanky brown discharge it makes me have a odor no matter how much I take a shower or shave ..also I always feel like I have to throw up , I have chest pain and my vigina be in pain , I'm really lazy , my face is breaking out I just don't know what to do it ruining me right now please help me ..I think it gave me a uti or interstitial cystitis F 16 4 months
Idk		 12/1/2013
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