DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth control and hormone balancing Insomnia. Weight gain, racing heart, heart palpitations, weak muscles, fatigue, crumbling teeth, bone weakness (bones started breaking easily, broke toe, foot and ankle on seperate occasions) anxiety, nervousness, migraines, abdominal issues. I underwent testing for all kinds of illnesses and autoimmune diseases trying to figure out what was wrong with me, spent thousands being referred from specialist to specialist. None of them suspected the shot until I changed go's and he said it might be the drop. I have been off it for 2 years now and although most of the side effects are gone, some still remain. This shot ruined my life. F 40 3 years
 2/18/2020
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 1  Birth control This medication has effectively ruined my life. I have zero energy. None. Fatigue and anxiety, that's my life now. I used to be vibrant. I used to have friends. My child and husband loved me. I'm isolated, in full body pain, my anxiety has taken the form of harm ocd and I don't have the energy to do anything about any of this. My sadness could drown me if I let it. And these symptoms came AFTER I STOPPED TAKING THE SHOT. During my time on depo I gained 20 pounds and get sad. Coming off depo was like jumping into traffic. I will always mourn the life I should have lived. Now I don't know if I will ever be the same. I feel bad mostly for my child, this has affected him the most. Mommy was wonderful now Mommy is an emotional, tired, fat psycho. F* depo. F 37 3 years
1X day		 2/4/2021
 5  Birth control, painful menstruation No period I have none of the negative side effects some other women suffer. F 25 3.5 years
1X AN		 8/17/2010
 5  Prevent Pregnancy First injection spotting continuously I began using depo when I was 17 and used it for 3 years. I spotted the first 3 months, afterwhich my period completely stopped. I was very satisfied with depo. I quit using it for awhile to get my body back on track. For those that believe you may not become pregnant after stopping depo. I became pregnant 6 months after discontinuing use and had a normal healthy pregnancy and healthy baby. I have recently started depo again because of the convenience (not having to remember bc pills) and also because not having a period and cramps is a lifesaver to me. All birth controls affect women differently. If you want to try it, by all means try it, if it doesn't work for you then stop. F 24 3.5 years
 6/23/2006
 1  Birth control no sex drive, painful intercourse,migraines,slight weight gain,cant concentrate,mood swings I have been taking the depo shot for 3 and a half years and recently have been getting sick lately so i decided to look up depo on the internet and seen a lot of stories that are similiar to mine. Although i have not had any weight gain, i started the depo shot after i gave birth to my son and i cannot lose any of my pregnancy weight. I have steadily had a decreased libido and currently have no sex drive I have had migraines quite frequently and on my last shot(2weeks ago), i actually felt the medicine go through my leg and burn. I am not going to take it anymore and i do not reccomend depo to anybody. When i started taking depo in 2002 all i knew was their might be weight gain and slight bone loss I wish I knew now what i did back then M 21 3.5 years
 1/27/2006
 1  birth control Some bleeding while on it, but it's what I have gone through since discontinuing use that is bothering me I started taking Depo in Sept 2003. I was informed about the possible side effects, I even read the package insert. In fact, I took it and read it every time I had the shot. I don't remember anything on the insert about the hair loss part, but perhaps it was there. Primarily, I think like MOST PEOPLE dealing with MOST FINE PRINT, you think, "Well, probably not a huge big deal and the percentages of women reporting issues are really small in these tests. Probably all ok." Well, ok.....given the amount of information I have gathered over the past 9 months, I really have to think the problems are underreported in the fine print. I went off the shot because I was not in a relationship, not sexually active, and wanted to give my body a break after 3.5 years on the stuff. I knew it wasn't long-term good for my bones. Well, I can't speak for my bones, I haven't had a density test yet. I CAN, however, speak for my swollen, spongy, non-stop bleeding uterus, my twitching ov F 40 3.5 years
 1/6/2008
 1  Birth Control Anxiety (in the weeks following the shot), constant hunger, blood sugar issues (symptoms of low blood sugar 2-3 hours after every meal), fatigue and depression (in the weeks leading up to the next shot), weight gain, complete loss of sex drive, vaginal dryness, mood swings, severe water retention especially in hands and feet. I started taking depo-provera in May of 2012 because I was sick of having periods. Mine weren't painful on the pill or anything, I just didn't want to deal with them anymore. The only reason I ever took hormonal birth control in the first place is because my cycles were pretty irregular, and it stressed me out when my periods were late. The first couple of years on depo-provera were fine. I started weight training, so I figured the 5 pounds or so I gained might be muscle. However, I kept gaining even though I had a strict diet and exercise regimen. I was starving all the time and miserable. I cannot stress enough how horrible it is to be that hungry constantly. Over the past 12-18 months, my sex drive has disappeared completely. It's really hard for me to reach orgasm, which was never a problem in the past. Also, I've started retaining water in terrifying amounts despite drinking several liters of water per day. My anxiety levels go through the roof for several weeks after a depo injection, to the point where I have a hard time leaving the house except for going to work. This drug is so dangerous, and no one wants to talk about its long term effects. I just want to be normal again. F 29 3.5 years
4X O		 11/9/2015
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 5  2013 Sore breast, and tired F 23 4 years
 1/27/2016
 5  birth control I was on depo 4 yrs last year I had 2 shots last shot was 6/7/13 In Aug. started having nipple tenderness heat in nipples stomach cramps & preg symptoms. 1/28/14 I had a 3 day period bright red mild cramps at the end of Feb. I had breast tenderness & enlargement pelvic area hard & laying on stomach feels like I'm laying on a golf ball & hurts when I lay on it as well as blood pressure elevated to 187/111 ive been off depo almost 10 months & that 1 period in Jan & not pregnant. Never take DEPO its a silent killer. F 35 4 years
 4/3/2014
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 5  Birth Control Weight gain of at least 20 pounds, however I have no period or period-like symptoms, my sex drive is completely fine, and I have no health problems to speak of. F 18 4 years
1X AN		 10/20/2013
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 5  To cure painful periods & cramps Increased appetite (can be controlled!) I had horrible cramps on the pill, even though my periods were extremely light. I also had breast lumps and swollen lymph nodes under my arm pits by the time I was 21. Depo took away all these problems. Only symptom was increased appetite, which I learned to control. I had no spotting, and no pain what-so-ever. I just went off of depo, because I have been on it for 4 years, and am not liking the pill! Take calcium supplements with your Depo! Even though Depo was great for me, it is not for everyone, but if you suffer from the same symptoms I did, I highly recommend trying Depo. F 27 4 years
 7/21/2008
 5  birth control and regulate period none bad.. i havent had my period in 4 years but i like that.. other then that nothing. my 48 yr old mum uses it to.. she has cancer and was getting heavy periods so tried it cause it was an issue she didnt need on top of everything else.. we are both really happy with it F 22 4 years
 6/6/2008
 5   Acne, although not sure if directly related. Weight gain, however I will not give myself that excuse, I've always fluctuated in weight, I definately could improve my diet, I do believe that it contributes mildly, however I believe a lot of women use it as an excuse. Please note that I am not saying that some women don't gain weight because of this shot. Occasional minimal spotting, nothing even worth mentioning. I see it as a reminder to get my next shot. I do notice I get more emotional when I first get the vaccine, but I am an emotional person, it goes away. Nothing serious. I do get frequent headaches, but I don't know that it's related. I started taking Depo-prevera after joining the military. 1 min showers and running doesn't make for a happy woman, especially with the added inconvience of your cycle and cramping. I started on a pill, but when my period exceeded 2 weeks I became frustrated and demanded something else be tried. I was warned that it might not work, but I didn't care. It actually worked very successfully for me. I have pretty much been on Depo for over 4 years. I love it, even if I wasn't married and sexually active I would continue with it. It's nice not worrying about your cycle and the discomfort assosiated with it. I thought that it was decreasing my sex drive, but since I got out of the Navy a few weeks ago and my stress levels are decreased and I'm not working 50+ hours a weeks while going to school full time, that's changed dramatically. It's not for everyone, but it's definately for me. F 23 4 years
 11/6/2007
 5  birth control weight gain I loved Depo! I was on it for four years and the only side effect I had was weight gain of about 15 lbs. I had no periods but mild spotting occassionally. When I went off off it, I was able to get pregnant about a year later with no problems. I highly recommend it! F 26 4 years
 9/8/2007
 5  bad cramps & terrible mood swings no period, only for a day in 3 months. got me out of depression. no weight gain or weight loss. happy as ever. still have a few cramps once in a while but not as bad as when i wasn't on it. its the best birth control out there. i don't have to worry about when to take a pill. this shot keeps me in a good mood. when i wasn't on it my cramps were so bad...i wouldn't sleep for a week, i was constanly vomitting, and my hormones were all out of wack. this shot keeps me focused and keeps my hormones and moods in check. F 18 4 years
 8/14/2007
 5  Birth Control 10 pound weight gain, no period. As everyone is different, Depo may have different effects on each individual woman. Some bleed still, others don't. Some get crazy side effects, others feel it is great. For me, I get no periods instantly, no spotting ever. I have discontinued before and got pregnant within 9 months of my last shot. I had my daughter and got right back on the shot when she was 6 weeks old. I do suggest to eat foods high in vitamins and calcium. I also suggest taking a "break" from the shot from time to time. I do not think it is a good idea to stay on this medication for years at a time. 2 years at a time I think should be the max. If you feel like you have adverse reactions to medications in general, then depo isn't for you. F 25 4 years
 9/17/2007
 5  to prevent pregnancy decrease sex drive Depo Provera is a great help in my life. Cramps no more, acne no more and PMS no more. I am off of Depo now for 3 weeks and my acnes already start to compete for places to grow. I cannot wait to be pregnant now that my husband and I are ready to be parents. Hope soon! F 27 4 years
 4/13/2005
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 5  Birth-Control/Painful Periods No Negative I have been on Depo for almost 4 years and have had no period or any serious problems. In fact the drug seemed to control my mood swings and food cravings (probably due to the fact that I had no period). I recently switched to the pill and often forget to take it and I have gained over 10 lbs in two months. My face, chest and back now break out occasionally and my sex drive has lowered. I think that you should talk to your doctor and look this drug up on official websites due to the fact that everyone's body is going to react differently. Case in point- my best friend tried it because I love it so much and she has had nothing but problems for 6 months straight. F 23 4 years
 1/12/2005
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 5  avoid pregnancy and cervical cancer When I first started getting the shot, I did so because I was told that it helps protect against cervical cancer which killed my mom when she was only 27. The first year of the shot were fine. After two months I stopped having a period, but my face started breaking out a lot. At the time I figured it was because I was a manager at McDonald's and it was the grease at work, but I have worked in a call center for more than a year now and my face still won't clear up. Also, I noticed my hair was starting to get thinner between the second and third years. More and more hair was coming out in the shower and in my brush. Once I entered the fourth year, I started having severe back pain and was constantly feeling sick, I even gagged up stomach acid quite a few times. The stomach cramping was so severe that I had to call off work for days at a time and Midol wasn't helping (and I never had cramps in my life, no matter what time of month it was). The worst part though, is that I have gai The drug did what it was supposed to do in terms of keeping me from getting pregnant, but the side effects are not worth it to me. F 22 4 years
 5/11/2006
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 5  Birth control None For the record, I think that most of the woman complaining about depo are insane. Depo will not cause you to gain over 100 lbs. Not eating right and not excercising for years did that. It will not give you toe fungus or any of the other crazy "side effects" that some of the woman have listed. Depo has been wonderful to me. Its a long term way for my husband and I to not get pregnant. No side effects, no weight gain, no crazy unrelated horror stories at all. VERY FEW people have ill reactions to this and other medications. For most of us this is a great birth control that you only have to think about 4 times a year. It completely stops you from having any periods, or PMS and everything associated with a period. I love it and so does everyone that I've ever known that has been on it. F 25 4 years
 4/3/2006

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