DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  prevent pregnancy nausea, mood swings. insomnia for the past nine months. caused anxiety and stress. i was tired all the time. i did not know that it can take up to a year for your menstrual cycle to return to normal. i stopped taking it because the side effects arent worth it. it does protect against pregnancy but in the long run it causes you more problems. it put a strain on my relationship with my long term boyfriend. i would constantly yell at him and get mad at him over nothing. i do not recommend this for anyone. F 20 9 months
3 times
6/24/2012
Email
 1  birth control Depression,anxiety,body aches,Headaches,random bleeding. This shot is pure evil and made me a totally different person. I feel sick always. I would love to sue F 30 9 months
3 shots
7/31/2012
 1  Forgetful w/ pill, shot convenient Weight gain, stomach pain after sex, low sex drive, vaginal dryness, frequent spotting and bleeding, depression, mood swings, and headaches. Would not suggest this birth control method to even my worst enemy. It should be off of the market because of the side effects. When I got my first shot, I weighed at 128. I'm only 5'1 but my curves spread out evenly so I didn't look fat at all. I didn't work out or eat too healthy before the shot. Just weighed my natural weight with no effort. Now, after three shots, I weigh nearly 150. I gained 30 pounds with absolutely no change in lifestyle. And that's not even the worst of the side effects. I can hardly have sex without bleeding everywhere, especially towards the end of the three month time in between shots. My "period" is completely unpredictable, ill bleed off and on, and I mean intense bleeding NOT spotting, for up to three weeks of a month. Also, there's intense stomach pain after sex to the point where I almost vomit. My sex drive has completely disappeared, which is not normal for an 18 year old hormonal girl in a loving relationship with a very attractive guy. The vaginal dryness is terrible, makes me feel like a post-menopausal woman. The worst of the side effects would definitely be the depression and mood swings. This recently started after my 2nd shot. Ill cry myself to sleep for no reason, I have a great life. Anything my boyfriend says can throw me over the edge and turn me into a raging b****. I recently stay F 18 9 months
1/15/2013
 1  Pregnancy Prevention/Painful Period Gained 45lbs in 9 months. Felt constantly hungry. No other side effects but weight gain. F 21 9 months
4/15/2013
 1  Contraception Bloating, fatigue , nause, headaches , mood swings , muscle weakness and pain , weight gain , hungry all the time , constantly in pain , and my stomach feels like its stretching . F 20 9 months
1/1/2013
 1  Birth control Hair loss, low sex drive, pain during sex, mood swings! I hate it!! F 33 9 months
11/13/2012
 1  birthcontrol constant bleeding for the first 3 months, then no periods at all until 12 months after coming off the depo.Gained 2 stone.Low self esteem,tired and moody. Now i am finding it very hard to concieve. It is good at it's job but the after effects are devistating. Please reconsider if you plan to have more children in the future. I only took it so i wouldnt get pregnant straight away after having my son. Now we are finding it difficult to give him a brother or sister. It's not worth the heart ache. F 21 9 months
8/16/2006
 1  birth control hair loss, joint pain, loss of libido, weight gain F 24 9 months
11/3/2005
 1  to reduce PMS symptoms constant heavy bleeding for a year, including five months after going off the shot; insomnia, night sweats, intense anxiety and depression my worst complaint about depo-provera has been the horrific combination of anxiety and depression that almost drove me to suicide. i didn't know the shot caused this until i found sites of horror stories, but thankfully i know that eventually i'll be able to get through the day without struggling through yet another crying fit. and for those of you still recommending the shot: it does affect all women differently, but it also causes early osteoporosis. come on, get with the f-ing program. F 23 9 months
8/25/2006
 1  birth control ANXIETY AND DEPRESSION!, hair loss, greasy hair, skin and breakouts. I started taking DP 9 months ago. The first 3 months was just fine, my mood improved and I felt that this was the right BC for me.. I was wrong. I have a history of anxiety but DP has maximized my anxiety levels farther than I ever thought they could be. I worry constantly, freak out all the time, and it is affecting my relationship with my boyfriend so badly that it was in shambles. Every little thing disturbed me, even when I knew it was nothing, and I still continued to pick at small things day after day. It made me a crazy person who worried about anything I couldn't control when normally I am very laid back. I also have very dry skin, which has now become oily and I break out in places I never had before, not even during puberty. I dont have a period however I would love to have them back if it mean i didn't have the side affects I do now. My hair is thinning on my head and also is greasier now than before. I am beginning to discontinue my shots and hope that these side affects go F 23 9 months
10/13/2008
 1  help with heavy bleeding extreme weight gain, decreased sex drive, no lubrication, mood swings, constant bleeding I took the shot three times, and was told that it was my last option to control my extreme bleeding before going on lupron. I still wanted more kids, but was not told about the extreme side effects of taking this medication. Now I have been off of it for 6 months and have only had one light period over two months ago. I feel miserable, and don't know how long I can take this. F 25 9 months
12/11/2006
 1  birth control 70lb weight gain, depression, panic attacks, hair loss, acne, mood swings, loss of sex drive, low self esteem DO NOT TAKE THIS DRUG OR LET ANYONE YOU KNOW TAKE IT. ITS HORRIBLE AND DESTROYED MY LIFE!!! F 23 9 months
7/9/2005
 1  Birth Control Extreme Fatigue, Body Aches, Change in mood, Abdominal pains, Appetite change. I would not recommend this form of birth control to anyone, because I started getting the shot having no ideal I would be the one to get side effects. I had been wondering why I was so tired and moody, and after reading all of these reviews, it made sense! I was not myself anymore, it was horrible. I felt trapped in someone else's shoes. I had no emotion most of the time, I wasn't excited about anything. I am constantly tired. My stomach would just hurt, worse than cramps for no reason. One day I would eat, eat, and eat. And others I would eat and want to puke. It has got in the way of my happiness and is effecting my relationship with my boyfiend. Although these side effects don't happen to everyone, I would not take the risk if I was anyone else. F 18 9 months
1X AN
2/10/2011
 1  birth control, no periods fatigue, lack of libido, feeling flat, no periods (by injection every 3 months) I stopped other BC as it seemed to increase heavy bleeding but the depo has a whole other set of side effects. The worse is the fatigue and effect on sex drive. I have never had the dryness before and I am greiving for the lost intimacy I usually love with my husband. Now it is just a mechanical act. This feels like menopause. I can't wait for this 3 month Depo injection to wear off as I will never have it again. It is not worth it. Fatigue has slowly crept up and is really bad now. My iron seems good so it is not that and yet I wanted to cry last night as I had to make the bed. That is not right. Can't wait to get the depo out of my system and try to heal from the damage it has done to my hormones, possible thyroid? F 39 9 months
3X AN
3/14/2011
 1  birth control always tired, always wanting to cry, Horibble cramping in my stumach, migraines... Never ever ever take this drug. It may be nice not haveing to take your birth control every day but it is soooo not worth it. I am thankfully going off of it this coming month thank god and am never taking it again! F 19 9 months
3X M
3/17/2011
 1  Birth Control headaches, joint pain, stomach upset, sharp pains in head, neck, and back, itching, rashes, muscle weakness, insomnia, chest pain, shortness of breath, weight increase, dizziness, excessive bleeding for weeks, passing out, PARALYSIS!!!!! My 17-year-old daughter took her 1st injection of Depo in early Feb 2010. Less than 6 days later, she was having "tremors" in her head/neck/arms. It started out a few here and there, lasting 30 seconds to 10 minutes. Over the course of a month, the tremors progressed to 10-12 hours a day STRAIGHT! She was unable to attend school, went to the ER multiple times, and was told to go to a psych hospital. Finally, after an ER visit, she was admitted to the medical hospital. CT scan showed nothing, so they told us it was "all in her head", that she possibly had a "conversion disorder" and needed to be admitted to a psych ward. A week later the tremors almost completely disappeared. Over the course of Feb - Dec she has complained of a multitude of side effects. The tremors returned 11/17 and she passed out very frequently. As of this past Wednesday, 12/1/10, she was unable to walk w/out assistance. As of Friday, 12/3/10, she cannot walk at all and is now in a wheel chair. CT scan with contrast, lumbar puncture, extensive blood work all came back normal. She had MRI done yesterday, EEG & more extensive blood work done Friday. I suspect it will all come back normal if the Depo Provera indeed has caused her paralysis. Today she woke up and can't swallow!!! I am probably going to have to have home health care come in to help me take care of her, as after 3 days of lifting her up from the couch, to the wheel chair, to the bathroom, has abou F 17 9 months
1X O
12/5/2010
Email
 1  Endometriosis & pregnancy prevent. I have taken the Depo shot for 9 months, and have gained 17 lbs since I've been on it. I run 3 miles 3 nights a week and eat 1500 to 1800 cal a day. It is almost impossible to shed any weight. I don't understand why I keep gaining. I have to take an estrogen pill every day in addition just so I won't bleed. (I bled for 6 months straight). I have no sex drive and get easily down. I will be going off of this shot in Dec. I def think I gave it a chance and there is still no balance. Little bit scared to see what happens when I go off of it. F 30 9 months
1X O
9/27/2010
 1  Birth control Weight gain, body deformation- it killed the muscle where they gave me the injection and caused a permanent dent on the side of my hip, i have a history of clots and it can kill you, the doctor was aware and prescribed it anyway. the worst side affect is that it completely destroyed my hormone balance and caused a horrible rash that i have been suffering from for almost 2 years and going... i was on 9 months and now off for 1 1/2 years and the rash is not going away. it has been a living hell! DON'T TAKE THIS DRUG I had weight gain that i could not loose no matter how much i worked out. It deformed my body where they gave me the injection. it killed the muscle and caused a permanent dent on the side of my hip. It was also wrongly prescribed by the doctor. i have a history of clots that he was aware of and it can kill you. the drug company tells you not to take it if you have had clots. the doctor refused to agree is still giving it to patients. the worst side affect is that it completely destroyed my hormone balance and caused a horrible rash that i have been suffering from for almost 2 years and going... this was the worst mistake of my life!! i don't know how long it will be in my system but i am desperately trying to figure out how to purge it out. I was on for 9 months and off for 1 1/2 years but the rash is still making my life miserable. If anyone knows how long it will take to purge this poison please let me know. Or how i can purge it from my body using natural means. tx F 38 9 months
1X AN
11/23/2011
Email
 1  extremely heavy periods hair loss, acne, tearfulness, anger, sudden period cramps, increased sex drive, 4 month period got this for heavy periods, first 3 month cycle i spent the whole time crying, then upon getting second injection i had a heavy period for 4 months (haemoglobin went down to 7), it amplifies my negative moods a thousandfold. When I brush my hair, so much hair comes out it's a wonder i'm not bald. I keep getting spontaneous, agonizing womb cramps as if i'm going to have a period. I'm on my 4th jag now and all I want to do is hump things, i'm constantly horny. I haven't gained weight, rather I've lost it. I keep getting huge spots that I never had before I started. F 17 9 months
4X O
7/17/2011
Email
 1  Birth control I really and truly regret using the depo shot. i started it october 2010 and continued to get two more shots until may of 2011(no bleeding)but because i noticed i was having side effects like really bad head aches and weight gain my bf suggested i discontinue. so...i didnt get the shot on may 3rd as scheduled and my cycle came on the 11th and continued until like the 27th of may then stayed off for like two months(i thought i was pregnant or something)and now it is aug 5. my cycle came back on aug 1st.i thought it was going away yesterday(which would be normal for me) but it came back today full force! im soo scared i hope it doesnt last as long as it did in may or longer!!! i will totally kill myself! i start my sophmore year in college on the 22nd and i just really dont need this!!! why is there no answer?? scientists find time to clone lambs and make tiny robot cars but no one can cure this nightmare???? they could have at least been considerate enough to warn us!!!!! F 19 9 months
150 MG 3X AN
8/5/2011

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