DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 4  birth control method alot of weight gain, mood swings (irrability and depression) I love the fact there is no period and that you don't have to take a daily pill. F 40 3 years
 11/25/2005
 4   Weight gain, loss of sex drive, no period Depo worked great for me but I'm going off of it for now to see if the side effects will go away. It stopped my period instantly, no spotting or anthing and no cramps! but over 3 years I have gained 35 pounds and exercise and dieting don't do anything. also my sex drive kept decreasing and is now practically non-existant. I'd say it is great, but perhaps not stay on it for more than a couple years and be sure that the side effects are worth it. F 23 3 years
 5/17/2006
 4  Birth control Weight gain, no libido I have a hard time giving Depo responsibility for me having a lot of the symptoms described here by others; I have had depression for many more years than I've been taking Depo, for instance. But it does make me wonder if I'd feel better without the shots...? I so enjoy not having a period though! F 39 3 years
 10/15/2006
 4  Endometriosis 10 lb. Weight gain, lack of sex drive, flat moods (rarely had mood swings, lost my passion!) and varicose veins I have taken Depo for almost 3 years, and it has helped my get rid of my endometriosis that was discovered on my right ovary during my tubal ligation several years ago. But, I am tired of the negative side affects, particularly the weight gain and the lack of sex drive, which I see is very common. I was miserable with pain every time I had a period before, and during ovulation. So, for me it has been a good thing for the symptoms I went in for, but I think it's probably not a drug you want to be on forever. If the endometriosis returns, I may opt for a complete hysterectomy, and while i am hopeful I won't have to go this route, it is no fun being in pain. I have had my children already, so fertility is not an issue for us. But, I can see where women would be very concerned about the long term effects of this drug. I am anxious to discover how "normal" feels. I am definitely moving into menopause, but it may feel good to be back in some sort of rythym with my natural h F 45 3 years
 3/15/2006
 4  birth control spotting, spotting, spotting! Dryness during intercourse (leading to painful intercourse), and reduced sexual drive Although I have experienced reduced sexual drive, and very irksome spotting that has lasted the entire duration of my use of this drug (3 years), at least I have not had the same wild mood swings as I did with the pill. With depo, I've retained my normal, even mood, and I attribute that to my sticking with depo for so long. F 27 3 years
 8/17/2004
 4  contraception none until stopping the shot It was great while on the shot. Since stopping the injections I have lost 15lbs (I am already underweight), had pelvic pain, no periods still (6 months after last injection), breast tenderness and horrible bloating-I'm getting another injection tomorrow F 22 3 years
 12/16/2004
 3  To regulate menstruation Weight gain, lethargy, worsened acne, increased depression, loss of lubrication and sex drive. I started taking depo because my periods were very heavy and painful, even on the pill, and often associated with migraines. Initially I had a lot of spotting but this was still preferable to my period, and then the bleeding stopped altogether. As long as I got my injections on schedule, I could prevent the spotting, and had no periods or migraines. However, I did have a history of depression before I started depo provera and this worsened the longer I stayed on it, and changed as well. I used to be a skinny insomniac who survived on the occasional candy bar and couldn't nap if my life depended on it... on depo, I gained close to 50 lbs and was so tired all the time I spent whole days sleeping, only getting up to eat. When I was awake I was cranky and irritable, and I lost all interest in sex, and even if I could dredge up the urge it was dry and painful. My teenage acne returned with a vengeance. At this point, I need to lose the weight and regain my old level of activity or I will very shortly become Type II diabetic, according to blood tests. I have decided to stop taking depo, and with the help of Weight Watchers I am already losing the weight. I am only spotting now, but I fear my horrible periods will return soon... I would still recommend depo provera to someone with very painful periods, but the depression (which also causes weight gain and loss of libido) whould be watched closely and treated if necessary. F 23 3 years
 11/19/2004
 3  Endometeriosis Weight gain. Caused me to loose some of my hair. Still bled. When I first started on it, my doctor put me on "triple depo" to prevent me from bleeding as I had severe endo. Due to the amount of depo in my system my hair started to thin near where your bangs would be. It took 10yrs for my hair to grow back in fully. F 35 3 years
1X M		 3/30/2013
 3  Preventing pregnancy at first I was fine for the first year but the next couple of years I experienced 15 pound weight gain.. Basically if you exercise everyday you will be fine other than you will gain weight. I would had extreme stomach pains and anxiety (from college im not sure). I also noticied an increase of food appetite. I was satisfied that you only take, one shot and not a pill everyday. Did the job of not getting pregnant but with weight gain as a side effect. F 20 3 years
20		 12/21/2011
 3  prevent pregnancy great till i went off it I loved Depo while I was on it. I never had to worry about anything: pregnancy or periods. But now that I am off it I have been on my period for two months with no end in sight. I mean bleeding, cramps, mood swings, and depression. I hate it. My fiance and I fight all the time about it now. I feel miserable. F 23 3 years
4X O		 4/10/2011
 3  yes Headaches, weight gain, mood swings, loss interest in sex. I started taking the shot when I was 16 when I first my boyfriend who I am still with today. I am still on it and it is time for me to get my shot again.. Im deciding if I should get it again or not. I did gain weight. I used to be 140 and a size 7 now Im about 170 and a size 13 and Im thinking its from the shot. I have always had headaches but I think there worse. Im always tired and I never like having sex.. Im 19 im pretty sure i should like to do that. Just wondering if i should get it or not... F 19 3 years
1X O		 9/23/2010
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 3  contraception un godly amount of weight gain- 70 lbs!! but since coming off of it (nearly 9 months ago- have only had 2 cycles-- but have lost 30 lbs of the gained bit! F 22 3 years
1X O		 12/8/2010
 3  Birth Control Weight Gain, Bone loss I gained 18 pounds on depo, wich is really hard to loose the weight. Normally I would just diet and my weight would go down, but diet and exercise isn't cutting it!! Also I just got a bone density test and it shows that I have osteopenia which is close to osteoporosis. Creepy!! Good thing about this no periods which decreased my migraines. F 23 3 years
1X AN		 2/25/2010
 3  Birth control Weight gain,emotional instability, vaginal dryness, chronic yeast infections, reduced sex drive, no periods to lots of periods, and tendonitis? I started on depo after having a medical abortion. I noticed the emotional instability immediately after taking depo but attributed it to the events at the time. Every time I was due for a shot I got extremely emotionally unstable. My husband joked that depo worked by making me not want to have sex. I gained about 20lbs (on top of already being overweight) and had no periods the first year on depo. I then decided to lose weight and worked really hard and lost 75 lbs over 2 years, and now I'm back to being extremely athletic and active but was hoping to lose the last 20lbs extra I have on my body (which seems to be all around my mid section and base of my extremeties) now that I just stopped my injections. After about 1 1/2 years on depo I began to get my period a week before my shot, then 6 months ago I got two periods, one week apart before my shot. I was due for a shot two weeks ago. In the last eight weeks I had 4 periods(every other week). After reading posts I believe my tendonitis might aslo be from depo, and not "inadequate stretching". I'm not looking to get pregnant but I'm sick of feeling like a chemical inbalanced mess, I feel like I have been noticing more and more negative symptoms now that I weigh so much less! So I'm done with depo and hope I will finally go back to "normal" for my husband's sake! F 29 3 years
1X AN		 8/2/2010
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 3   RASH AFTER 3 YRS OF BEING ON THE SHOT. I DECIDED TO GET THE SHOT AFTER I TERMINATED A PREGNANCY. I WAS THRILLED TO NOT HAVE A WORRY OF BECOMING PREGNANT. THEN I HAD THE REACTION AND HAVE BEEN OFF OF IT FOR 6 YRS. I CAME ON HERE TO FIND OUT IF ANYONE ELSE HAS HAD IRREGULAR PERIODS AFTER BEING OFF OF IT TOO. WHAT I MEAN BY THAT IS...NO PERIODS AT ALL. SOME MONTHS. EVEN 2 MONTHS IN A ROW..? WHEN I DO HAVE ONE IT IS CLUMPY AND GROSS..NOT FLUID LIKE USUAL. I WENT TO THE GYNO AND THEY EXPLAINED TO ME THAT NOW THEY ARE SAYING THERE IS A TWO YEAR MAXIMUM FOR BEING ON IT... F 34 3 years
 11/19/2009
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 3  to not get pregnant mood swings, mild weight gain, massive hair loss, headaches, backaches, month long periods, extreme fatigue, always hungry, aching hips and legs, feeling soreness in my body as if im 70 yrs old, loss of sex drive It absolutely blows my mind that I was never informed about all of these changes. I tried to ignore them thinking it was just my body changing but thanks to this website I now know it it eventually happens to everyone! I've been taking this shot wayy to long almost 3 years an will not get my next shot. The only good reviews on this site about this shot are people who just started taking it and they will eventually find out that its not as great as it seems to be in the beginning! F 21 3 years
 10/28/2009
 3   I started using the injection 3 years ago and was ok with it, lucky for me I didnt have any side effects but then when I red other comments things started to come to mind which I was experiencing and never thought much of it. I found that sex was painful and I had alot of pains in my arms and legs. I am coming to the end of the 3 months and I cant say that its not for everyone because you dont know unless you try it out urself but I have heard alot of bad comments than good but I will not be continuing the use due to trying for a baby in a few months which I hope the depo has not affected my chances. Alot of women like to take the drug because some women dont get their period for 3 months ( like myself which I loved) but think in the long run, you dont need to take a drug if you dont need it. F 24 3 years
 8/1/2008
 3  Heavy bleeding, no to get pregnant When I had my son 3years ago I got my first injection . It was gone until about a month ago. My nipples were very sore, heavy bleeding one hour then the next its gone. Been like this for 3 weeks. No cramps. Don't. Know if it's hormonal or if I'm preggers Use at your own risk F 30 3 years
 12/9/2014
 3  to prevent preegnancy vaginal dryness,abdominal pain,weight gain,overall feeling of un well,extreme decress in sex drive only good wasno period until i stopped it after 3 years getting a period every 2weeks! does exceptionally well preventing pregnancy F 19 3 years
 1/24/2010
 3  Birth Control weight gain, mood swings, adult acne I was on the depo for 3 years. I gained and lost weight depending if I watched my diet with a fine tooth comb. However, when I would get off my diet, I would gain weight at a rapid pace. I am now off depo and look forward to being healthy again. F 24 3 years
 10/2/2007

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