DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  BIRTH CONTROL COMPLETE LOSS OF LIBIDO!! weight gain. apprx 5lbs. mood swings. depression, headaches. BOO TO DEPO wow, i recently got off of taking depo. 2 months later, still feeling the effects, but getting better. i can't wait til i feel myself again! i couldn't figure out why i felt this way about sex, and then i started doing some online research and i found out that many women had these same side effects! vtw, it's made my relationship rocky but luckily my boyfriend is understanding...when i talked to my doctor about it, they said they had never heard of these kind of side effects (loss of interest in sex) they did say that women report having a dryer vagina because it lowers estrogen, and they recommended switching to an estrogen bc instead. i can't believe after reading all of these women's comments that no one is doing anything about it. wow. F 22 6 months
 6/30/2007
 1  easier to remember than the pill. I experienced every side effect known, plus many more that my doctor had never seen from the shot! I gained huge amounts of weight, terrible muscle and body aches, extreme headaches, no sex drive, vomiting, nausea, severe stomach pain, and many more! To top it all off, I now have had to take other meds to get my period back! Still am not completely back to normal and it has been over a year!!! Would not recommend it for anyone at any time!! F 25 6 months
 2/16/2005
 1  prevent pregnancy depression, muscular aches, headaches, backaches, chest pain,irregular menstruals, and many many more. F 20 6 months
 3/28/2005
 1  contreception constant bleeding,memory loss,anxiety,difficulty speaking/ thinking clearly,depression this stuff is absolute shit! DONT GET ON IT!!!! the doctor told me all his patients loved it and never had a problem w/it so i started taking it and have had my period the entire time on my first shot i went from a size 6 to a size 9 then when i was sopposed to get my next shot i started stuttering and messing up on words and stuff i couldnt think clearly at all it felt like i was losing my mind then i got my second shot late and it went away they told me it would help the bleeding but its just the same as before i also went from a size 9 to a size 3 this time cuz i went on a diet ( depo makes you gain 200 cals on top of everything you eat) and i feel anxious all the time its almost time for my next shot and im starting to have alittle trouble thinking clearly but nowhere near as bad as before i think im gonna get on b/c after 12 weeks and see if it helps i will NEVER do this again F 18 6 months
 5/10/2005
 1  birth control Acne, Bleeding, Fatigue I had the shot twice a while ago. My acne became a lot worse and I bled for 7 months. I also felt really tired which may or may not have anything to do with Depo. My skin is still really bad. Don't take this stuff! F 21 6 months
 1/27/2005
 1  Convenience Weight gain, loss of sex drive, vaginal dryness, mood swings,chest pain now that I've stopped it nausea, headaches, dissiness, tingling hands, chest pain I decided after taking depo for 6 months (2 shots)not to have my next shot as it had totally killed my sex drive. Now 3 weeks later I am feeling absolutely horrible. After seeing my doctor he sent me to the hospital as he couldn't explain the shortness of breath and chest pains and thought I may have a heart problem. The only explanation the ER doctors could come up with was that I'd stopped Depo. For the last week I've been having shortness of breath, needing to yawn all the time, feel like I'm going to throw up but don't, dizziness, tiredness, chest pain, tingling an numb hands and hot sweat, and terrible headaches. The doctor said this was likely to be the changing hormone levels in my body. They really should tell you the risks before you take depo, if I'd know this could happen i would definitely never have taken it. Please think twice about depo. F 27 6 months
 1/12/2005
 1  birth control weight gain. 20 lbs in 6 months. migraine headaches, constant and often severe neck pain, sore stiff muscles, achy joints, mood swings, Did i mention weight gain? The information given by my doctor and the leaflet are very misleading. It does not mention these kind of serious side effects. Who knows what else this drug has done to me. F 31 6 months
 3/9/2004
 1  birth control EXTREME DRYNESS leading to PAINFUL INTERCOURSE. causing me to stop sex mid way through.. loss of sex drive along with the pain made it very effective considering the thought of having sex made me cringe. 10-15lbs weight gain. some mood swings that leveled out after the first month. headaches, body aches. chest pain. bloating, gas, abdominal pain. I was on depo for 6months. and refused to get my 3rd shot because i was so dissatisfied. i was unsure of what was directly causing my side effects, but after finding this website i am convinced they are all caused from depo. i have been off depo for roughly 3 months, i have regained only a quarter of what my sex drive used to be, i have a hard time becoming aroused. intercourse is still painful, luckily my boyfriend is very understanding but i feel it is still straining our relationship.. intercourse feels very tight, even with the use of lubrication and easing his way in. after only a few minutes it begins to make me feel as though i am being "rubbed raw" inside and i have to ask him to stop. it is sometimes so painful that i am brought to tears.. i PRAY that this will go away. i feel dysfunctional. as for the weight gain, i do not know that all of it can be blamed on depo. i have now renewed my gym membership and working out 5-7 days a week doing cardio. i have lost the majority of what i gained while on the shot. i would never recommend the shot, and i wish i never had it. F 18 6 months
 8/10/2009
 1  endometriosis pins and needles in my legs; extreme moodiness and some depression. Very poor sex drive and depo is not helping with the endometriosis pain. Doctor had recommended this due to my recent diagnosis of high blood pressure. On Pfizer's own site (about 4 months ago) they had a warning about depo provera stating that no one should take this BC for more than 2 years due to the severe osteoporosis that is coming to light for users who used it more than 2 years. This concerned me since my doctor never gave me any printed information about side effects (that's why I was on the official site-- to find out if my side effects were caused by the medication). That part of the site is no longer accessible, so I wonder if Pfizer is circling its wagons, so to speak (maybe litagation is starting to happen??). I will not be receiving my 3rd shot in July. F 36 6 months
 6/10/2009
 1  Pregnancy Prevention MOOD SWINGS, HAIR LOSS, VERY PAINFUL INTERCOURSE, BLEEDING DURING INTERCOURSE, RANDOM BLEEDING i HATE the Depo shot. i've only been on it for 6 months & i'm already unsatisfied. the first couple weeks on the first shot were okay, my sex life was normal, then progressing toward the end of the cycle, i began to bleed during sex, & later it became extremely painful where my partner couldn't even get in. i visited the doctor to be safe & i found out i had a mild yeast infection. i took the medicine i was given, however, i was still randomly bleeding & sex was extremely painful. i began to get uncomfortable irritation in my lower parts, so i visited a personal doctor to do a pap smear which came out normal. although i was still experiencing irritation, mood swings, depression, & my sex drive was a -4.. even after i had a normal pap smear, sex is still very painful, so its obvious its the birth control. i have also lost a lot of hair, some by strands & by chunks... i thought something was wrong with my body, until i read reviews about the shot & realized that's what causing me so much trouble. i would definitly NOT recommend this form of birth control. F 6 months
 8/25/2009
 1  Birth control ACNE! Dislike this form of birth control, I have never broke out in my life and ever since I got the shot in October of 08, I've had non stop acne, last shot was March 19th 09 and I still have not had a period and I still am breaking out BAD. I feel like this shot has ruined my face. I'm so unhappy in life right now because of what it did. Other than that it is okay. The bad thing it can stay in your system up to 15 mths, so don't take if you are thinking about getting pregnant in the near future. F 19 6 months
 11/14/2009
 1  irregular bleeding bleeding for 6 months straight every single day, extreme depression and mood swings,loss of sex drive, weight gain (15 pounds), fatigue, dizziness, heart palpatations, headaches,vision problems,this is just a few of the side effects! I orginally started birth control at age 15 due to irregular periods. After Yaz gave me extreme migraines, they switched me to a lower estrogen pill which brought be back to two periods a month. My doctor suggessted Depo and said it would cause my periods to STOP so I thought that sounded great and agreed. She didn't inform me that it could also have the REVERSE affect. I have been bleeding non-stop for over 6 months now and have thousands of dollars in medical bills from fainting and MRIs because I've been so dizzy and fatigued all the time. The mood swings are harming my relationships and affecting my work and school work. Complete loss of sex drive, COMPLETE! A new OBGYN informed me that 30% of women experience reverse side effects...I THINK 30% is ENOUGH TO WARN SOMEONE ABOUT BEFORE TAKING IT! There is nothing you can do to help the side effects except wait it out. I've been waiting 3 months, and no change. I am so unhappy with Depo and strongly encourage everyone to do research before taking it. DO NOT TAKE DEPO. It has ruined 6 months of my life and has messed up my body in so many ways. I was completely healthy before taking Depo. I would rather have 2 periods a month again than be bleeding everyday. The mood swings are unbearable. Slight acne has appeared, too. I'd do anything to reverse these side effects. WE SHOULD GET DEPO BANNED!!!!! All of this doesn't even begin to describe what it has done to me. F 19 6 months
 11/16/2009
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 1  Prevent Pregnancy Increase in migraines, weight gain (20 lbs), anxiety, spotting, acne, skin became oily I have been on it for 6 months. My next shot is supposed to be Dec 4, but I will not be taking it. I'm going back to old birth control. The weight gain didn't seem to bad and the acne could be cleared up with extra work in taking care of my skin; those were my thoughts after the first 3 months. I loved not having a period and not worrying about chronic yeast infections from the pill. Depo is so not worth it in the end. Our bodies just aren't meant to have something completely screw with our cycle like Depo does. After 6 months without a period, I began spotting out of no where. I have acne and have gotten 6 cysts in 1 month and have ingrown hairs all over my legs and have gained 20 lbs. I feel disgusting, not to mention the horrible anxiety I have been experiencing. I am a very strong person who has been through a lot and now I am terrified of everything and worried from the time I wake up to the time I go to sleep. Also, I have horrible vivid nightmares every night and migraines. Apparently my body is trying to tell me that something isn't right and it's obviously the Depo. I know it sounds like a wonderful idea, but it is not worth throwing your body out of whack. F 22 6 months
 11/26/2009
 1  pregnancy prevention Very HEAVY non-stop bleeding to the point of hospitalization (entirely from the medication and my thin bodytype), dizziness, head aches behind the eyes, fainting spells, decreased bone density levels (I take my calcium/magn/vit D every day since before teh shot) which lead to fractured bones. Intense mood swings, depression. Biggest waste of time! If you are experiencing ligth side effects during the first shot - do not take the second shot! Please, learn from me. F 6 months
 4/4/2009
 1  Pregnancy Prevention Weight gain, depression, mood swings, angry, irritable, pain in knees, shortness of breath, vaginal discharge, vaginal dryness, no acne (which is good), bloating from everything I eat, it sucks, don't ever get it, it's the most horrible thing i've ever allowed in my body. F 24 6 months
 4/2/2009
 1  birth control very moody, continuous bleeding, irritable, depressed, abdominal pain, back pain, pelvic pain. My girlfriend took her last depo shot about 7 or so months ago. She took a 6month course of shots. it's been the wordst decision of her life. she's been on her period for 3 months striaght, every day, non stop. she has a very low sex drive, and is moody all the time. her back always hurts, and breasts hurts very often. do not take this drug. please. she wasn't warned about these horrible side effects and it takes a tole on her life, and especially our relationship. why doesn't anyone warn the patients?? F 19 6 months
 3/17/2009
 1  birth control EXCESSIVE BLEEDING! Hair loss, moodiness, low sex drive, fatigue, dizziness The only good thing I have to say about this bc method is that I did not gain weight, but I had every other symptom. I got my first shot in January and about a week afterward started spotting. I thought nothing of it, but I called my doctor after it had went on for nearly 2 months. Doc said that this would stop after the second shot, but instead the bleeding increased. I pretty much had a light to moderate period for nearly 6 months!!!! As a result I was always tired and started having dizzy spells. I was due to get my last shot in July and did not get it, yet I am still experiencing the dizziness. Now doc suspects that I am anemic. On top of all of this, I had excessive hair loss, which started out as more than normal shedding then increased to my hair coming out in patches. I had to get my past shoulder length hair cut to a short, spiky style, and my hair has still not totally recovered. Don't even get me started on the mood swings that ranged from me being extra sensitive to me bein F 25 6 months
 9/12/2008
 1  Birth Control EXTREME wait gain, headaches, EXTREME moodiness, anxiety, joint and muscle pain, complete loss of period I started taking the Depo shot 6 weeks after my daughter was born, by my second shot I had gained 60 lbs (after losing all of it and being down to my pre-pregnancy weight), I had completely lost my appetite and was barely eating anything (small salads and stuff to keep food in my system), but gaining faster than ever before. My period stopped all together which I didn't mind, but I was still getting bad cramping. I got bad headaches and my joints and muscles hurt all the time, I had NO patience for my baby and my friends and family said I was very moody and on edge all the time. I stopped getting the depo shot before my 3rd shot, and it has been 2 years and I have only had my period once since then, I still get bad cramps and joint pain, I haven't been able to lose the weight even after following a strict diet my doctor put me on, My Doctor said there are steroids in the shot that I didn't know about before I started taking it, and that's why I had such weight gain. This form of birth F 23 6 months
 9/12/2008
 1  birth control until essure worked hair falling out, extreme moodswings, anxiety, constant headaches, been bleeding for 5 out of six months. marriage ready to collapse. extreme moodiness, bodyaches, decreased sex drive. weight gain (15 pounds) hot flashes, i had my first injection the day after my little boy was born. I didn't sleep for three days after getting home. from that day i have cried at least once a day. my moods are constantly shifting and really hate what the shot has done to my previously happy home. I now feel like a crazy woman. I also feel very anxious for no apperant reason. I would not recommend this medicine to my worst enemy. F 28 6 months
 10/2/2008
 1  Period, birth control Nervousness, weight gain, depression, fatigue, constant bleeding, acne, hair drying out, loss of focus, mood swings, sore breasts, change in body temperature I took this because my insurance didn't want to cover my expensive birth control anymore. I should have just footed a little extra on the pills and been happy. I took one shot, and instantly I had acne, was sweating more, and gained weight. Then my period came in July and never stopped. I stupidly took a nurse's advice and had a second shot injected. My last shot was in September 2008. It's April 2009 now, and I still have weight gain, acne, dried-out skin and hair, and a plethora of mental problems. I'm nervous and anxious, and I can't focus on anything. I'm having a hard time doing anything, and I'm always tired and depressed. My breasts are sore and I can't walk a block without breaking into a sweat. Thankfully, the bleeding stopped in November, but only after I took other medications to stop it. I'm worried that my body is permanently going to stay this way. I wouldn't recommend this birth control to my worse enemy. F 21 6 months
 4/21/2009

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