DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth Control Massive weight gain, depression I have only had one shot of depo and will not be returning for my second. Things were fine for the first month or so but over the last few weeks I have gained weight at an alarming rate despite no significant changes to my diet. I seem to be gaining more weight by the day - clothes that fit me 10 days ago are now far too tight. I have experienced slight weight gain before on the pill but never to this extent. I appreciate that the side effects of depo vary from person to person but i urge anyone who experiences any amount of weight gain on contraceptives to avoid depo at all costs F 24 3 months
 7/12/2008
 1  birth control during breastfeeding anger, rage, restlessness, sex drive increase, annoyance, irritability, dissatisfaction I was ANGRY all of the time, at my husband, random strangers, even my poor 3 month old baby girl! I wanted to hit a wall instead of hitting one of them. I was restless, found it hard to sleep and my sex drive actually increased but I was unable to do anything about it as nothing seemed to satisfy it. I think the only solace I could get was going for a run until I was exhausted then a long bath. Minor annoyances would set me off, and I found it very hard to reason or focus. It did work as birth control - but I would never put this in my body again. F 29 3 months
 2/13/2009
 1  i had terminated a pregnancy, i experienced bloating, weight gain, depression, mood swings, hair loss, headaches, dry skin, a very foul odor from my vagina, and alot of discharge. i took the shot to avoid another pregnancy because i had just terminated one. i only took one shot that was in june. i got my period back in december about the 26 to be exact. during those months without my period i experienced all the symptoms mentioned on the left of the screen, now that my period has returned i have been experiencing pain, i mean pain during intercourse. i have to hold my stomach if i try to make a bowel movement or urinate. the doctor can not tell me what is wrong because he cannot find anything. but i know that it is from that damn shot. F 24 3 months
 2/16/2009
 1  birth control Weight gain, depression, mood swings, paranonia, insomnia, fatigue, lower back pain, increased hunger, memory loss, no energy, possible endometriosis, crying fits,delusions I think it really depends on the person but I took the shot in December and have nothing but negative side effects. The doctor warned me of the "normal" ones but if she told me how it really was going to be, I would have said no. Haven't been able to lose any weight even though I am working out at the gym almost everyday doing tons of cardio and strength endurance training. I am also hungry all the time too. I start fights with my boyfriend every other day to the point now that when I tell him I love him, he responds "love me today, hate me tomorrow." I haven't wanted to see my friends, pretty much avoiding them, even their phone calls. Crying spells all the time. Sometimes putting the cereal in the refrigarator and the shrimp in the cabinet and a few minutes later realizing what I did and trying to figure out when I did that; things I was already paranoid about being more intense like thinking that there are cameras in my room or someone looking at me from the ceil F 22 3 months
 2/19/2009
 1  prevent pregancy, regulate cycle severe mood swings; one minute frisky and over stimulated, next minute moody and depressed; crying for no reason; suicidal; steady bleeding for three months; dizziness, joint stiffness, loss of appetite and then raving hungry, hair drying out and falling out, extremely dry skin do not take this EVER for ANY reason; NOT EVEN ONCE; i only had one shot and will never take another one ... just can't til it leaves my system ... F 29 3 months
 1/13/2009
 1  Heavy periods Weight gain (set on fast); irritable (and I was the easy going one!); dizziness; fatigue and a 48 day period (and counting) I was a bad patient. I should have read more about it but I was about to do the 60 mile breastcancer walk and suffered from anemia due to heavy periods. The doctor said this would work. I'm on day 48 of my period which started ten days after the shot. I am just waiting for the side effects to stop - I would never take this knowing what I know now. F 45 3 months
 1/5/2009
 1  prevent pregnancy, regulate period Mood swings, backaches, headaches/migraines, loss of sex drive (completly), vaginal dryness, increased acne, loss of motivation, loss of energy, hot flashs, depression/thoughts of suicide, foul odor, no period of 1st 2 months then a constant 4 week period and counting... I got this shot because it was one of my only options (due to my history of headaches), but it is been the worst choice I could of made. My headaches have worsened (I had 5 in one day; including a migraine). I would never recommend this to anybody. I've never felt worse in my life. F 19 3 months
 12/23/2008
 1  Birth control I applaud anyone who has experienced wonderful effects of Depo but I will NEVER take the shot again. At first everything was fine but then there was significant hair loss, my period started 2wks late, then the irregular bleeding for 3wks and COUNTING. I can't even have sex! The bleeding won't stop. Its very dark brown and as soon as I think it has finally stopped it starts again! It's not healthy to alter your normal body mechanisms this way. I hate this progesterone. I just want the bleeding to stop. I've also had bouts of depression and I blamed it on myself without knowing the shot could have caused it. I will not return for the second shot. I would like to find a way to detox F 19 3 months
 12/7/2008
 1  For birth control After the first day of getting the shot I had horrible migraines the first month. They some what subsided but still got one at least every week or so and I never got them before. I had absolutely no energy and my muscles ached all the time. I also have extreme anxiety and tension that will not go away. Note- I have never had these symptoms before! I would like to see this shot off the market, it does more harm than good! F 21 3 months
 3/27/2008
 1  to prepare for essure procedure serious serious depression,mood swings,suicidal thoughts, weight gain, anxiety & panic severe, bleeding since nov 12 when i received poison, blurry vision,hot flashes, bloating, my breast now need there own zip code, constant fatigue, could sleep my weekend away, irratic thoughts, high blood pressure medicine now, loss of breathe, sex"whatever", just would rather be dead I too have asked this question 100 times, isn’t there a lawyer out there interested in doing the right thing for once...But wait possible not enough money in it for them and pharmaceutical companies have very deep pockets and high powered attorneys, my story is this I am 39 years old and chose to have my tubes incapable of releasing eggs, a new procedure called 'Essure" non invasive no cutting blah blah, so 2 months prior to procedure I had this poison also, yes it is POISON, it is a synthetic hormone that stops our body from doing what God intended us as woman to do , nerveless, I thought seriously that I had finally snapped from stress of being a divorced parent raising my children on my own, working a Very stress full joy and going through a divorce, I actually considered checking myself into a mental hospital, I gain 12 lbs just like that! eat less then EVER, moods like I have NEVER experienced, depression like I could care less if the house burned down with me in (I F 39 3 months
 3/17/2008
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 1  birth control I have migraines with aura so am unable to take the pill. The Dr. told me to go on depo, and told me NOTHING about the side effects. I spent 3 months in deep depresion, extremely decreased sex drive, gained about 15 lbs,had a massive increase in the severity and frequency of my headaches, as well as a non-stop period for the full three months. Once stopped the periods stopped, but I have not had one for two months! This Drug is BAD! DO NOT TAKE IT! F 26 3 months
 1/13/2008
 1  to not get a period Mood swings, weight gain and bleeding for over a month, not just spotting. F 22 3 months
 3/5/2008
 1  prevent pregnancy severe lack of sex drive and vaginal dryness so that i actually dreaded the thought of having sex with my boyfriend as i couldn't bear him to come near me, extreme irritability and depression and spotting throughout most of the 3 months i was on depo. The irritability was the worst side effect for me since i am a very laid back person, nothing fazes me but it got to the point where i had to sit with my ipod on at work all day long to shut everything out as every single little thing annoyed me to the point i would feel a rage building up inside of me which i have never in my life experienced! Unlike most people on depo though, i didn't gain any weight i came off the depo after only 3 months due to the side effects and expected them to disappear after stopping it. They didn't! the irritability continued although i am getting back to my old self now. I also experienced more symptoms coming off depo than i did on it. I have been off depo for over 6 months and during the past 3 months i have experienced pregnancy symptoms such as cramping, severe nausea, fatigue, acne (i have never had spots before), bloating and the most intense cravings for food (mostly chocolate) which i struggle to keep under control and have only managed to keep my weight down by jogging / gym sessions 6 days a week. I know i am not pregnant, I have done numerous pregnancy tests which where all negative. I can only assume this was the result of my hormones trying to get back to normal. The symptoms do now seem to be tailing off with only the odd bout of nausea now and sex drive is coming back. The only side effect i was warned about from my doctor was slight weight F 31 3 months
 11/2/2008
 1  birth control weight gain, mood swing, bloating, headaches, severe back pain. Depo Provera is driving me crazy! When I had my first shot I started bleeding for about 4 month. My Dr. gave me a second shot on January 2007 and syntomes get worse. I gained 15 pound, get depressed and irritable, had rash in my back, water retention and breast pain. I went to a new Dr. and did test my hormones. Now I can't lose weight, I lost my period (6 month ago), I have policystic ovaries, severe back pain and became insuline resistant. DP have ruin my life. F 32 3 months
 9/15/2007
 1   For birth control//and to have no periods I only took the shot for 3 months and it was the worst three months of my life. All my friends completely lost their periods, I had mine 3 weeks out of every month. Now that I have stopped taking it, my period won't stop. It's been 34 days of hell so far...when will it stop? F 3 months
 8/18/2007
 1  Birth Control My doctor wouldn't put me on the Pill for heart reasons, I've had only the 1st shot and I am going crazy, I can't stop bleeding I constantly yell and fight with my boyfriend, I am eating every 5 minutes, I'm paranoid about stupid things. I use to be the life of the party and now I sit home thinking everything is horrible. I can't have sex without bleeding. Its absolutley ridiculous!!! I hate it. I can't explain the way my body feels sometimes! I ache and feel crappy! If you are looking at getting on DEPO I recommend you read all these comments and side affects and then make a decision!!! F 21 3 months
 8/20/2007
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 1  Birth Control The Depo-Provera shot made me incredibly emotional, irritable, impatient and depressed. I felt like a different person. My appetite was much larger and I gained a few pounds (this was during the period of three months - I only needed one dose to know this medicine is not for me). F 17 3 months
 11/19/2007
 1  Birth Control Mood Swings, Weight gain, Loss of Sex Drive, Loss of Periods, Problems conceiving I took the shot only once. It took me over a year to regain my period. I then tried to get pregnant and did but only to have a very complicated miscarriage. I was then lucky enough to get pregnant and to deliver a healthy baby 2 years ago but I have not had a normal cycle since. I will probably not be able to have another child. The weight that I gained has been very hard to shed which is just added stress. F 24 3 months
 12/22/2007
 1  Prevent pregnancy and severe period Hair loss, weight gain (10 pounds), breast tenderness and growth, mood swings, emotionally unstable, UTI, painful intercourse, bleeding, migranes, no sex drive, nausea I started the shot two months ago and have had nothing but problems ever since. I had "morning sickness" symptoms for about two weeks and I was constantly nauseated. Up until starting the shot I had never had a UTI, I have either had one for the last three months that hasn't gone away or they keep coming back constantly. I have been in and out of the hospital for the UTI infections and a case of extreme constipation (I had to be hospitalized for it). My hair falls out in huge chunks. I have been bleeding for almost the last month straight with no stopping. But the worst symptom has been my constant mood swings and no sex drive. I have never been more moody or depressed in my entire life. I cry and get sad all the time for no reason at all, and there is no consoling me. I have almost no sex drive at all, and when we do have sex it is so painful that it isn't even enjoyable. All of my symptoms are starting to put strain on my relationship with my fiance. My next shot is coming up next month and needless to say I will not be getting another dose. I will be requesting another method. I would not recommend the depo shot to anyone. F 20 3 months
1 1X M		 4/6/2012
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 1  Contraception Worst.decision.EVER. Crazy mood swings, angry all the time, suicidal, hated everyone and everything I came in contact with. Normally pretty mellow but this turned me into a crazy person. I took Depo because I smoked at the time (since have switched to e-cigarettes) and didn't want to use non-hormonal birth control (i.e., "bullets" or "film" or "foam", sucks!) This stuff turned me into a completely moody hormonal crazy brawl-starting beeyatch of the highest caliber. I thought I was going to end up in jail or divorced. Libido? Laugh, what's that. No sex for hubby unless I felt too guilty. Kids made me crazy, hubby made me crazy, all the things I loved (snowboarding, etc.) I couldn't care less about. Bored, tired, angry, irritable, depressed...started thinking the world would be better off without me and my crazy outbursts. At the three month mark, told the doc in no uncertain terms that he wasn't putting that crap in my system again, and went back on Nordette, which I used several years ago with minimal side effects. Oh, I had one period which was brownish black blood and during THAT week, I was probably certifiably insane. Not looking forward to first Aunt Flo after going on Nordette, but this 3months at a whack stuff is NOT for me. F 40 3 months
1 shot 1X O		 1/24/2012
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