DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  birth control Depo was great at first, especially since it seemed to be the only thing that prevented unwanted pregnancy for me. However, I noticed the "doom" started setting in. I became extremely depressed, moody, gained weight, and started to get a lot of acne.I really didn't think much of it because it was so effective in other areas: I didn't have to worry about getting pregnant if I got my shot every 3 months. I've been off the shot for 2 months now (not in a sexual relationship anymore) and I'm feeling a lot more side effects than I had while on the shot: stomach pains, panic, extreme moodiness, fatigue, low self-esteem, overall negative self-image, a bit more weight gain, dizziness and nausea. I get these heart palpitations out of nowhere, which really freaks me out because I have never experienced anything of the sort. Until reading all of the comments, I didn't realize that my problems may very well stem from Depo. As this makes me feel a little more sane, I'm really hoping the s F 25 2 years
1X day		 7/21/2010
 3  bad menstrual pain-birth control Mood change, aggressive, angry, sad. Spotting, would eat a lot, gained weight. Bad smell down there. It was good because i didn't have to worry about pregnancy and my menstrual pain def. went away. I decided to get off the shot because i didn't like the mood change and the weight gain. After getting off the shot (2 years later) i started to experience bad side effects. Nausea is the worst, i can't eat like before, i feel like puking sometimes. Bad pains when i get my period to the point that i can't move. Having trouble sleeping because i feel sick and my digestive system changed. I also got stretch marks on my thighs, also my breasts have been hurting sometimes. If anyone has had the same symptoms please e-mail me, i want to make sure i'm not the only one and that it is because of the shot. F 21 2 years
1X M		 9/9/2010
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 3  Birth Control & Period No weight gain, No mood swings, nothing except weird periods. Started it at the age of 15 and I am now 17. I had my period for 2 months straight when I first got on the shot. After that I only had it very lightly at the end of the 3 months. I have now been on it for 2 years and just recently started getting a heavy period for about 2 weeks now. I am still on the shot but if i continue to have this weird heavy menstruation I will need to get off of it. It will go away for like a day and then come back pretty heavy and it isn't normal period blood. It is thinner and really red like when you get a paper cut...! Up until now it has been good for me. I also got my period during sporting events but that is probably because the shot makes your uterine wall thinner and weaker.... F 17 2 years
1X day		 7/6/2011
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 2  Pregnancy I started taking the depo shot in the middle of october 09, in the beginning I loved taking it no periods I've lost 30 pounds in a years time. But I've noticed I've been having panic attacks,really bad anxiety.. loosing my hair when I brush it and wash it it's in the drain and all over the floor, my breasts and nipples are very sore, i have experienced light headedness, feeling of passing out, hot and cold flashes, night sweats, mood swings, nervousness, Crying a lot and for someone who never cried I cry quite frequent, depression, My friends and fiancé have noticed I have change I'm not the same person I was. F 26 2 years
150mg 1X day		 4/8/2011
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 2  To lessing periods I've gained about 20lbs and my hair wont grow...I used to be able to lose weight really fast but I cant even lose weight on a 1300 calorie diet with exercise and my hair used to be long and full, now, it's breaking and dull. I also get extremely depressed and my bones really ache if I sit in the same position for more than 15 minutes...My bone mass scares me alot. I can't wait to get this drug out of my system! F 28 2 years
1X AN		 3/30/2011
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 2  To help with painful periods extreme fatigue, headaches 3 to 4 times a day, bloating, stomach pains, joint swelling and joint pain, confusion, and blurriness with eyes. I did not have these symptoms right away. It took about a year before they showed up. I was not sure it was the shot and went to my gyno first. She said the shot could not be giving me this trouble and sent me to a nuerologist. After many many test he could not help me. He as well said the shot was not the cause. I then went to a rheumatologist b/c of the joint issues. He too could not help. After researching the shot myself I then became convinced that I was having side effects from the shot. I just wish I had listened to my gut over a year ago when I started having trouble. I would not take a chance on using this drug. It is not worth it. F 35 2 years
1X O		 7/15/2011
 2  birth control n painful periods Hair lost, weight gain, increase appetiet, mood swings, fatigue..... I will not recommended to anyone. I have being taking it for 2 years n the first year was great. By the secound year I begun to notice hair lost, increse appetiet n milk comming out my brest. N lots more. I never stoped my period. My period was regular for 1 year but the secound i will last for 1 month. It is horrible. Right knw i am trying to loss the 20 lbs. I gain in 3 months n now im swiching to junel1-20 hopefully things get better. F 18 2 years
1X day		 7/12/2011
 2  not get pregnant Tiredness!!! When I first got the shot I got bad mood swings I lost my period and was happy bout that. I was fine on it at first but lately after being on it almost two years I am constantly tired no energy ever, backaches, breast pains, digestive problems, poor concentraton its really changed my life and I cant stand the new me. Its like I am a whole new person that I dont know and I cant wait to be off of it. F 17 2 years
1X O		 2/9/2010
 2  birth control/no period EXTREME MOOD SWINGS/ANXIETY/EMOTIONAL ROLLERCOASTER!!!! I started depo when I was 18 and was on it until the age of 20. At that time, I got off of it because my moods were out of control. The final straw was when three of my girlfriends from college came to my hometown to visit me and I got mad about something so little and snapped on all of them. But here I am 24 and I thought, hey, what the heck, I was younger then and probably couldnt handle the emotional changes, I'll just try it again now that I'm older (plus it's hard for me to remember to take the pill every night and I have really bad cramps and periods). ****NEWSFLASH**** THE SIDE EFFECTS DONT GO AWAY! Now I am in love with a wonderful man and since he knew me before I started taking the shot again, he's always saying how it changed me. We went on a vacation to Mexico and I snapped on him non-stop, and practically ruined the trip by my bitchy moods and lack of sex drive. Lucky for me, I have a good man that is willing to be patient until I am back to normal...but I know one F 24 2 years
 4/10/2006
 2  birth control Depression with no history or family history and no external reason, 55 lb weight gain in 2 yrs. Can eat and eat and eat and you never feel full. Don't take it! F 27 2 years
 11/28/2006
 2  Endometriosis/Birthcontrol 50+ lbs of weight gain!!! Moodiness, irritability, cramps, fatigue. I am a VERY active person. I have played college field hockey at a divison 1 level, so the work outs and dieting are very strict and hard. While I was on depo for two years during this process, I lost no weight at all, in fact I gain 50+ lbs. I have been off of depo for over 5 months and am having a very difficult time losing the weight. The doctor informed me that I may gain some weight, thinking 5 or ten pounds, but not 50+. Do NOT take this drug, not only has the weight gain affected me tremendously, but since being off of it my periods are VERY painful and my body is still suffering from other side effects of the drug. F 21 2 years
 4/21/2008
 2  To prevent Pregnancy At first I was a poster child. Once every three months is all I have to remember and no period! Where do I sign up? My first month on it too a little bit of time to regulate my periods, so I would have it on and off, however this wasn't that bad. When I used to have mine they were awfull made me tired and moody and weak and would last 5 days and be very heavy. After the first month it went away completely. I couldn't tell enough people how much I loved it. I noticed that I started to lose my sex drive and I was moody, but it still didn't bother me enough. On my wedding day I did not have to worry. Then after 2 years I got really sick. I had extreme GI problems and headaches (I never had headaches before) and body aches and abdominal cramps and fatigue. I started getting night sweats and just feeling awful. I have had every test. I had a CT scan and they did not find anything, except a spot on my liver. (They say that is related to the depo-provera shot/ birth control) I had a Please weigh all your options and discuss the side affects with your doctor. I had no idea I would have all of these side affects 2 years into using it. F 26 2 years
 2/4/2009
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 2  Birth Control wait gain, spotting 3 weeks a month, unexplained illness, loss of lubrication during intercourse, cramps, painful intercourse I have been on depo for about two years now and I dont think that I have experienced very many good things with this shot. The only good thing I found was not having a period. After being on this shot for about a year i started having irregular bleeding and spotting, i thought it would just go away but it lasted for 3 weeks straight, then it went away for a week and came back again for another 2 weeks. It was just like having my period for 6 weeks. After the bleeding stopped I started having pains in my kidneys and started vomitting, I went to the doctor with a 103 degree temperature and they did all kind of tests and ultrasounds, and guess what, they found nothing wrong, the only thing i could blame all of this on is depo. This has happened to me in 3 different instances now and they still cant find anything wrong. Also, I find that I can get mad over the smallest little things and I can get depressed very easily. I gained about twenty pounds but that didn't really bother me that much. Now my periods have gone away again for a while. But while having intercourse one night I started experiencing severe cramps and then I vomitted, this has also happened to me on a few occasions, I've had my physical and the doctor saw nothing wrong. I think I might go off of the needle becuase I'm afraid that it will affect my fertility in the long run, it just seemed like the most convenient choice for my busy life. F 20 2 years
 1/12/2005
 2  PREVENT PREGNANCY 20lbs weight gain in 2yrs, even though exersizing more than 3 times a week. Extremely decreased sex drive. Crying all the time for no reason. Lots of hair loss, thank God I had a lot of hair to begin with. Having no period was the only pro. Plan on stopping will try Ortho-tricyclene F 20 2 years
 2/3/2005
 2  bad periods bad cramps weight gain (nearly forty pounds) acne mood, swings to the extent of being diagnosed bipolar, migraines well it stopped the periods for the most part i never new i shouldnt take it for more than two years goof thing two years is the next shot.but i always have pimples never stable in my mood. and always in pain of some form or another F 20 2 years
 7/20/2009
 2  Endometriosis, Blood Pressure, B/C Severe Mood swings, Low Sex Drive, Irregular bleeding Due to a diagnosis of both endometriosis and high blood pressure, my doctor decided Depo would be my best option for not only treating the endometriosis, but also for birth control. In the two years that I have taken the shot, the only consistancy from the treatment was the inconsistancy. My weight fluxuated, my mood swings effected everyone one of my relationships, and the bleeding became a gamble: Will I bleed today or not? Not to mention the severe abdominal cramps. I have skipped my last shot, and hoping some of these symptoms will go away... No not take this shot. The risks FAR outweigh the advantages. F 34 2 years
 11/8/2009
 2  not become pregnant nausea,headaches,loss in sex drive,major mood swings, gained weight,being unhappy for no reason, depressed.hot flashes, and being a time bomb. at first it seems all cool then its like your experiencing so many symptoms.who would wanna feel depressed like half the time.not recommended if your in a relationship or have any social gatherings. its just not worth it. F 20 2 years
 8/4/2008
 2  Prevent pregnancy Ive experienced lots of weight loss since ive been taking the depo over the past two years. In the past of my younger years Ive maintained my weight n picked up a few pounds. Im not liking the results this time so im going to let it go. F 32 2 years
 1/30/2017
 2  Prevent pregnancy First year irregular bleeding clots but that could have been after my son Cramps Headaches at times Dizzyness Ibs symptoms struggling to go but mainly loose when going the loo Dishcharge I've lost weight lack of appetite The only reason I kept taking it was because I've tried other options F 29 2 years
 3/20/2017
 1  Prevent pregnancy Took shot for two years, always had periods and sometimes two periods a month, stop taking it and ended up with horrible painful cyst in breast, brown discolored mark across top lip and night sweats.. It's been 13 yrs since last dose and these symptoms never went away, tubes tied now and ended up with premenstrual dysforic syndrome horrible periods with some months needing a hormone to make me stop bleeding. F 23 2 years
 4/20/2016
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