DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth control Spotting sometimes several times each month. Anxiety, paranoia, depression, and anger that seemed to come each month during PMS time. Would usually last about 2 weeks. No sex drive. Depo may work well for some people, my best friend loves it. It made me feel like I was going crazy. I have decided to quit taking it. F 31 1.5 years
 2/24/2009
 1  prevent pregnancy Most of all I gained weight! I am 5'5 and I went from a skinny 117 to a big 180! My body looks so bad from all the stretch marks. Other than the weight which is bad enough, extreme vaginal dryness, decreased libido, I now have hypertension, and moodiness which also caused extreme jealousy. I quit doing Depo and ever since I can tell the difference. It was the worst mistake I made in my life. F 18 1.5 years
 1/16/2009
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 1   Extreme Nausea, Severe Calf and Stomach Cramps, Headaches, Backaches, Extreme Fatigue where I dont want to get out of bed, Stomach Pains, Mood Swings, Depression, Breast Tenderness, Smell Sensitivity, No period after a year. I was fine taking depo until my 5th shot, I then came down with all these symptoms and my doctor did not tell me about the loss in bone density and how long it will take to get pregnant afterwards. I won't ever go back for my next shot. I'm supposed to go back February 28th, I will be switching back to the pill and hoping my body will go back to normal. Never take this medicine! It's horrible!!! F 19 1.5 years
 1/19/2009
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 1  Birth Control Severe weight gain (75 pounds) decreased sex drive, mood swings, depression, no period and fatigue. I went on depo after giving birth to my daughter since I got pregnant on Ortho Tri-Cyclen while taking an antibiotic (my Dr. forgot to tell me about that side effect) and was a little weary of bc pills. I did not have a period for the year and a half that I was on depo but the weight gain and other side effects outwayed that one. I am currently on Ovcon 35 and am pleased with it so far. I have lost 10 pounds, have more energy, the depression and mood swings went away and my sex drive came back. I would NOT recommend depo-provera for anyone!!! EVER!!!! F 21 1.5 years
 4/4/2005
 1  birth control blinding migraines F 23 1.5 years
 3/16/2005
 1  irregular periods it made me blled for 6 months straight and I am still bleeding the crap needs to be taken off the market F 17 1.5 years
 1/31/2005
 1  Birth Control Acne, Mood swings, NO sex drive, no energy, no periods, MAJOR weight gain (70 lbs) I thought this would be great, no taking a pill everyday, no period, ect. But this was horrible I felt sick a lot and it made me have HORRIBLE back acne and face acne. I have huge scars on my back from the acne. I NEVER wanted to have sex, gained 70 pounds!!! EW! Hate this drug and I can see why it is illegal in other countries F 19 1.5 years
 7/26/2008
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 1  prevent pregnancy headaches, dizziness, fatigue, heart problems I began taking depo a little over a year ago. I started experiencing heart palpitations, headaches, dizziness and fatigue about six months after the first shot. At first I didn't connect the two. After numerous doctor visits and tests they were not able to find any "medical" reason for my symptoms. I now fully believe that depo is the root cause to all of my problems. Needless to say, I will not be getting my next shot in July. I now just have to wait it out and hope that once this poison leaves my body my symptoms will go away completely or at least get to the point where I don't have constant headaches everyday. I wish I had known about these issues before starting. Next time I will do my research prior to accepting someone telling me that the positives outweigh the "possible" negatives! F 26 1.5 years
 5/14/2009
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 1  Birth Control Weight gain, depression, moody, loss of bone density, anger, nausea, migraines, hot flashes... The first 3 months were not bad.. I actually lost weight... I did have morning sickness for some reason, but I was not pregnant because I wasn't sexually active at the time.. the next 3 months.. ugh .. the depression started to happen.. moodiness.. slight weight gain.. I also noticed that when the doctor gave me the shot in my arm.. I didn't have as much depression or anger.. I got it on the hip butt area.. and ugh.. I had really bad mood swings.. now after taking it over a year my husband just hates the shot.. he wants me off of it and to never go on it ever again .. I also have loss of bone density too.. so that sucks since I'm only 23 years old.. My last Dr. said this shot is so bad he wouldn't even recommend it to his daughter.. He wasn't going to even allow me to get it through his services.. so I had to tell him I would be off of it after this... besides I don't want to be on it anymore.. and if he thinks it's that bad.. I know it can't be good for my body .. too many side effects .. I mean I like being covered for 3 months.. and not have to worry about a pill.. but I guess I'll just go on a pill and see if they can regulate some hormones.. I'm on Ortho tri cyclen right now and it has taken away the hot flashes.. so yay.. and also it's helped with moodiness.. so I think I'll just stick with this pill :) F 23 1.5 years
 6/23/2009
 5  birth control I was on the shot for 2 years. High sex drive for a month then low sex drive for a month and so on and so forth I have been on the implant for a year and i am switching back to depo provera , because i am sick of the prolonged bleeding and headdaches. F 21 2 years
 8/27/2009
 5  To prevent pregnancy No or minimal periods. It helped reduce my cramps when I had a period. I seen all of these negative comments about Depo and I thought it was strange that I didn't have any of the mood swings or anything. I liked not having a period and no cramps. The only things I don't like is the possability of bone loss(the main reason I stopped taking it) and not being able to get pregnant right away. If it wasn't for the bone loss issue I would definately get back on it after we have another child. F 23 2 years
 12/4/2009
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 5  Birth control Some spotting during the first few months. I had ONE spot on my face where I would get an acne cyst about 2 weeks after the shot, which would eventually go away. Decreased sex drive, but not sure if that was due to the shot or my loser BF! Love it! After several months, stopped having periods. Shot is quick and easy and you don't have to worry about forgetting to take pills. I have taken pills before and they make me spot continuously. Depo caused some very minor spotting, which went away after a couple of cycles. I did not gain any weight. F 32 2 years
 4/7/2009
 5  Birth control Gained about 15 pounds, no period, stronger sex drive I gained about 15 pounds but with diet and exercise lost 30! No period except for about 2 days of spotting every 3 months. Sex drive seemed to be at least twice as strong. I LOVE DEPO. <3 F 20 2 years
 5/29/2008
 5  Extremely painful cramps/cysts Night sweats, minimal amount of spotting after first and second shot, small increase in headaches which eventually goes away at the end of the first month after shot, had painful intercourse only once. I truly consider this medicine a god send. I was diagnosed with very large ovarian cysts when I was 15 and they caused very heavy bleeding to the point I was anemic, and very extreme and sudden pain that would put me in floor. The doctors would not operate because I was so young and because of the chance of infertility and hormone changes. They put me on the pill to shrink the cysts, but after a year, the pain came back and the cysts grew so I decided to agree to the shot. The pain is completely gone, no heavy period- just occasional and very infrequent spotting, and my cysts have shrunk immensely. The only adverse side effects are that a few weeks after the shot I have frequent night sweats and headaches. I would recommend this to anyone with intense menstrual cramps. F 18 2 years
1X O		 1/22/2015
 5  Birth Control Weight LOSS!!!! experiencing some acne, not bad at all, two years after starting the drug, increase in OCD? (don't know if it's related or not) I love this form of birth control! I tried two different types of the pill before trying the shot, the first gave me depression and the second was just a mess. I was warned about weight gain when starting the shot but I actually lost weight when I started. I've been exercising daily since the start of the new year but I hadn't always exercised. I take a calcium supplement once a day to help with the bone density loss, but who knows if that's doing anything. I read that repo is for long term use. I plan to stop taking it and jump right back onto the pill after three years. I've heard that depo can take a while to leave your system and become fertile again, but that's why you just have to plan ahead. I've read a lot of reviews that call this drug poison and don't recommend taking it, but you can't listen to that. it's good to know what is possible to occur when taking the drug, but it's also good to know that EVERYONE IS DIFFERENT!!!! depo is a dream for me and a nightmare for others. you just have to try it out, for longer than just the first or second dose, and see how you like it. don't let the fear of what might happen keep you from trying it. F 20 2 years
1X day		 3/27/2014
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 5  Birth Control only good side effects: not getting pregnant, no periods, no cramps. Also no weight gain. Love it! I've been on it for two years and I would take it even if I could not get pregnant. The freedom of not dealing with cramps, no bleeding, very low risk of getting pregnant, and I lost weight (5Lbs). I have nothing bad to say about Depo. F 27 2 years
 1/5/2005
 5  birth control irritability Loved it- no periods, no worries! F 27 2 years
 1/25/2003
 5  birth control I didnt experiance any side-effects. I lost a lot of weight because I didnt have week-long cravings as I had before my period, and was able to lose 20 lb. I stopped have any acne, my face looks much more better.no changes in sex dive at all. I get calcium suplements. F 24 2 years
 1/12/2009
 5  Birth control, no periods I have not had any of the side effects listed by all these other women. I think it's a great thing - no period is the best! It is hard to lose weight, but that was no different than when I was not on depo. I would recommend it. F 46 2 years
 11/6/2007
 5  prevent pregnncy no side effects until after 2 years when i began to get angry and moody and was bloated constantly for the first 3 months i was having periods every 2 weeks, after the second they stopped immediatly and it was fantastic. didnt have to worry about being "on" ever. when i began to get moody and bloated i discussed coming off it and back onto the pill with my boyfriend, we agreed id go back onto the combined pill but since going back on the pill 2 months ago ive had no periods, spotting or anything. my doctor said i should have some signs of spotting. my breasts are painful, very painful whilst im taking the pill but are fine whilst on the 7 day break. ive constantly got headaches and sleep all the time, i dont know if this is because of the hormones in the pill that im not used to after 2 years on the depo. can anyone shed any light??? if it wasnt for the moodiness and the fact that i want children in the near future i would stay on the depo F 23 2 years
 11/1/2008
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