DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth Control Serious weight gain, loss of sex drive, bloating, what I can best describe as a "false pregnancy" almost At first I loved this drug. I liked that I didn't have periods on it, it's very inexpensive, and you only have to think about it once every 3 months. However in the 4 years I was on it I gained 40 lbs. and I have no doubt it was the Depo's fault. Not only did I gain weight, it was IMPOSSIBLE to lose until I went off of it even with dieting and exercise. I went from a size 5 to a 12, which is just ridiculous. I had absolutely no sex drive. So if that's the "birth control" it offers.... LOL! The once a month bloating was terrible. Made my jeans fit even tighter, thus depressing me. The final straw was the pregnancy symptoms I got. Breast tenderness, mood swings, and morning sickness. I wasn't pregnant but I sure felt it! I'd never recommend this to anyone. It also depreciates the calcium in bones, which I think is reason enough to have it pulled off the market since it is for women. I now take Orthocyclen, skipping the placebo/spacer week (as directed by my OB/GYN) so I still don't have periods. I have none of the side effects I had with Depo and have finally started to lose the weight I put on. F 26 4 years
1X O		 2/6/2010
 1  birth control hot flashes, night sweats, anxiety, insomnia, infertility, nausea I didn't have any side effects on the medication, it was when I stopped taking it that the hell began. I had horrible anxiety, hot flashes, smells made me feel ill, and insomnia. It has been awful, the symptoms were worse when I first got off the medication. However, some of the symptoms have lasted for years. Not to mention the fact I have been unable to get pregnant since getting off the shot. But who knows if you can blame that on the birth control. I am SURE the other problems are due to the shot though. Oh, and I've lost bone density. It really is terrible. I wonder if my body has trouble getting rid of the fake hormones. Anyone else have an idea about this? F 31 4 years
1X O		 10/11/2010
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 1  BAD periods Weight gain, SEVERE mood swings, ovarian cysts, hot flashes. Sure... It prevents pregnancy. Sure it prevents periods. SUre its great. Well guess what... U R WRONG! I got put on this when I was 14 yrs. old. I am now 19 and trying to put myself back together. been off of it for a whole year.. No periods!! Guess what?? You cant have babies with no periods!!! I havent been able to lose the weight, I still have bad mood swings, and on top of everything... I might have end organ failure (uterus doesnt work) due to the depo. Dont do it!!! It might seem worth it now, but think of the long run!!! F 19 4 years
1X AN		 12/8/2010
 1  Contra.. Am start taking depo after my second child all the time am thinking its ok but it dosn't ... in last year iv got strong depression am ruined my marriage no period over 4 yr but am strong bleeding in last 1 month my weight its the same like 4 yr ago everythink what am report to Gp they tell me its ok but now they think i got the cancer :( Think before use them that long time 26 4 years
3X day		 11/4/2021
 1  Pregnancy prevention So I've always been at about 120-130 pounds and for awhile I didn't experience any side effects but more recently over the past year I've gained an additional 30 pounds, I have a ton of stretch marks on the back of my calves that are super dark and stretch marks in other places as well. I feel like I am always hungry, I've been getting severe headaches that I was told was allergies but I've never had that problem before taking BC, VERY low sex drive, and I am constantly tired. I have to take naps during the day or I feel exhausted and start nodding off. F 17 4 years
1X day		 9/1/2020
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 1  Control menstrual cycle Depression , weight gain , heart burn , severe anxiety, confusion, hair loss... And lots more Do not recommend! Two years after taking the injection started getting many problems , also don't know if caused by the depo but low blood pressure, low sugar , low iron, and a massive decrease in red blood cells. F 21 4 years
120 MG		 5/16/2016
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 1  Birth Control No period since starting. No noticeable side effects for first 2-3 years then began getting increasingly unwell with extreme fatigue. I would not recommend to be on this birth control for more than 2-3 years. Very appealing not having a period but i believe looking back over the four years i was on Depo i started having unusual health problems starting with abnormal pap smear, neck pain/stiffness and tingling/numbness in hand. then when i reached the 3 yr mark i began having hearth palpitations, dizziness and a constant gurgling/rumbling in my stomach. This then developed into food intolerances and IBS. I also suffered from reflux, indigestion and felt sick every time i ate resulting in a 12kg weight loss over about 8 months. Numerous testing and Doctors couldn't find anything wrong and didn't suggest i should go off the Depo. even after i questioned if I've been on it too long. I decide myself to stop my last injection due 4 weeks ago and am now starting to feel like myself again. I DO NOT RECOMMENED FROM PERSONAL EXPERIENCE TO TAKE THIS DRUG AT ALL OR NO LONGER THAN THE RECOMMENDED 2 YEARS. I had never suffered any of these side effects before DEPO !!! F 41 4 years
1X AN		 5/26/2016
 5  eliminate period, birth control breakthrough bleeding once in 4.5 years I loved this medication, it completely eliminates the period. I had no side effects at all, except for one instance of breakthrough bleeding. I started on depo because I had severe cramping and heavy periods. However after 4.5 years of being on depo my mother insisted I get a bone density test and the results were bad. Basically I have the bones of a post-menopausal woman now. It has taken around 11 months from the time of the final shot to get a period again. I take 1600 mg of calcium daily and lift weights three times weekly. I will have another bone density test in Jan. I highly recommend this medication but only for short periods of time. I am now on the pill, Ovcon, and do not like it at all. F 22 4.5 years
 9/2/2005
 5  contraceptive; no estrogen None. First I'd like to start by saying that depo will affect everyone differently and you can never know how it will affect you until you've tried it. If the negative aspects are ones you are not willing to deal with, you may not want to try it. Personally, I have had great success with depo and it's hard for me to imagine it can be bad for some people, but I know it's possible. I have been on depo for 4.5 years now and absolutely love it. I feel like it's a miracle drug! My periods stopped immediately after the first shot and I only had slight spotting once or twice within six months of the first injection. Ever since, I have been period-free and PMS free. I used to have terrible periods- extreme bloating, heavy bleeding, unbelieveable hunger which lead to weight gain, and horrible yeast infections with every period (associated with the estrogen levels in my body- depo has no estrogen, thus no yeast infections for me!). I have NONE of that after being on depo and have even lost weig F 24 4.5 years
 5/30/2006
 3  contraception, no periods! Weight gain! Gained 20 lbs. Fatigue, depression and anxiety. Some acne when I started. Loved the fact that I didn't have my period, but the weight gain and fatigue just became too much.I didn't feel like myself anymore. F 24 4.5 years
 3/8/2005
 2  To prevent periods Weight Gain, Loss of Libido, No Periods I have gained 30 pounds since starting Depo 5 years ago. I have experienced a tiredness and weakness since starting Depo, but I also started a blood pressure medication at the same time so I can't be sure which, if either, are to blame. My last injection was 9 months ago, and I haven't started a period yet. I am still having a struggle loosing weight, even with exercise. I have also had leg pain while exercising since starting Depo. I would really suggest another form of BC, I am sure I have damaged my hormonal balance, and hope it's not permanent. F 33 4.5 years
 4/30/2005
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 1  birth control severe weight gain [about 50 lbs]. mood swings. fatigue. anger. depression. acne. i wouold not recommend this drug to anyone. it can mess you up. i have to admit, no periods is nice. but all of the side effects of the shot is not worth it. i had about a 50 lb gain in the 4 years or so i was on it. i tried exercising and dieting but nothing helped, i just kept gaining. i am a 5'1 an petite. an weigh 175 lbs now. i had no problem with wieght until i started taking depo. while i was on it, i had severe mood swings an depression an suicidal thoughts. i recentley got off of the shot on 01/14/09 and am having severe breast pain an cramps as if i have a period but i am not having one. but on the the plus side i have felt so much better since i've been off of it. i have more energy, no mood swings, an no depression.it is not all what it is cracked up to be. email me if anyone has any questions. F 21 4.5 years
 3/3/2009
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 1  severe bleeding/cramps weight gain,hair loss,brittle bones,acne,bloating, I was originally put on depo because my monthly period was so severe in cramping and bleeding i couldnt get out of bed and was near blood transfusions. At first i loved it because i didnt get a period and the cramps were gone. I was 14 when i got on the depo and i am now 18.5 years old and just recently got off of it because of the horrid side effects and because my obgyn insists that i switch. now that i am off it(last shot was in august 2010) i now have worse cramps then i ever have before, it can take up to 9mnths to get my period and clean out, i am having vaginal pains, my bones are so thin and frail is unbelieveable and my body is just messed up. I DO NOT RECOMMEND DEPO AT ALL. F 18 4.5 years
1X day		 11/29/2010
 5  Birth control/ ovarian cysts Tenderness at the injection site. Morning sickness during the first few shots. I began this injection for ovarian cysts, and continued it because I loved it! No bleeding, no headaches, no acne, no cramps. I never gained a single pound that wasn't intentional!! In fact, it actually curbed my appetite. I have heard horror stories about all types of birth control...including this one. But I love the depo shot. Once every three months and no bleeding. It's great. I'm sure it will react differntly to certian body types. Love it! F 23 5 years
1X AN		 2/25/2010
 5  easier than remembering the pill The depo shot was great while i was on it and i got my last shot 3 months ago and now ive got all of these strange and to be honest scary side effects: dizziness blured vision. Extreme hot flashes. and just feeling over all weird. Has Anyone else experienced these symptoms after GETTING OFF depo F 20 5 years
1X M		 4/19/2010
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 5  No period, can have sex when I want My side affect on the shot is that I want to have sex all the time. So I love it, it's the best thing that ever happen to me The shot isn't for everyone, I been on the shot for five years and I just love it. And I know a few more people thats on the shot and they love it also. It's just different for everyone F 24 5 years
1X AN		 6/12/2010
 5  BC I love it so much,no periods no side effects at all.A wonderful birth control. I believe some of these people are trying to scare others. The only thing I feel is sleepy the rest of the day after I get it, but no big deal rather have that then a child! F 20 5 years
Normal 1X AN		 9/5/2011
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 5  prevent pregnancy Beginning brown discharge that went away, around the time for my next shot i feel light bloading, eventually have no period. Ever. In the beginning brown discharge and eventually no period. I cant even remember the last time i had a period and i dont have any more discharges either. I LOVE depo it is fast, non-complicated and reliable. But it is not for most women!!! if you do not react normally to other birth control methods such as the pill or ring you will probably react horribly to Depo (weight gain, mood swings). As a teenager i had light periods and no weight problem might be why Depo works great for me. My doctor said now that i am a long term user i need to take Calcium Pills and exercise regularly, which i do :) F 24 5 years
1X day		 4/18/2011
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 5  to avoid periods moodiness,headaches F 27 5 years
 4/25/2006
 5  to prevent getting pregnant i took depo for 5 years from 1996 to 2001 and i gained weight but it worked great. no babies since coming off the depo shot i have been diagnosed with high blood pressure ( that is why the doctor stop giving it to me in 2001) due to all the wieght gain. i was 125 pounds when i got on it i was 170 when i came off. i am only 5'1 that is a lot of weight for my body. i also was recently diagnosed with a hyper active thyroid with no family history of this problem. if i could go back i would never have taken this shot because i am only 28 and i have a lifetime ahead of medications from side effects. F 28 5 years
 3/13/2007

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