LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Uterine Fibroids Extreme weight gain, memory loss and hair loss and shedding. Lupron injection given in June 2014 and I am still experiencing all of the side effects except for the hot flashes. This drug is horrible and certainly didn't help to shrink my fibroids. In fact, I am bleeding 10 or more days straight. F 39 1 months
11.25mg
3/3/2015
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 4  Prostate cancer Stage 4 I was taking Lupron in 6 month shots. I had two 6 month shots, and after 1 year, my Doctors & I decided to switch me to 4 month Lupron shots. Before, I really was feeling so bad that I was making arrangements to have a bilateral Orchectomy because of the side effects. Doctor team met and discussed my case. At this time I have been declared cancer free from a Stage 4. Bone scans, CT Scans, and MRIs are clear. At this time I must say I am feeling much better on the 4 month Lupron shots. I still have slight leg muscle and joint aches, but nothing like before. As of my last blood tests, my testosterone level is down to <10. The standards are to have it 20 or below. So, I feel like the Lupron is working fine at this point. My PSA continues to be at a steady <0.010. Had one testosterone flair, one month before I got the 4 month shot. It had climbed to 47, but then dropped to <10 the week before I got the 4 month shot. Doctors were surprised. My doctors are still M 69 1 years
30mg 1X M
2/18/2015
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 1  Prostate Cancer Stage 4 Some hot flashes, Muscle and joint pain and muscle weakness in legs. There are times that I can barely walk. Some back and pelvis discomfort.Weight gain (7-10 pounds), more frequent urination (worse that with the enlarged prostate), numbness in hands and fingers (I'm a pianist, and that doesn't work too well). overall lousy feeling at times, mood swings, crying at the least little thing, pain in testicles. Testicle atrophy. Breast size increase and tenderness. My head hair continues to get thicker. Wife comments on that when she cuts my hair. I had a radical prostectomy Dec 10, 2013. I was a stage 4 with a small spot in one lymph node. No cancer in the surrounding tissue. 6 month Lupron shot in Jan. then 8 weeks of external radiation starting in May. I had been a road cyclist. I continue to do up to 2 hours per day on a stationary bike and tread mill, plus weight training. PSA at 69 pre surgery PSA was at 0.2 after surgery Went on Lupron and PSA is now <0.010, and holding at 0. Post Lupron Testosterone was at 27.78, starting to rise and is at 45.28. That's twice what they want. We are switching to a 4 month shot to try and relieve the side effects. There is concern about the rise in testosterone, however my PSA stays at <0.010. I've been on Calcium and VitD and brought my levels up. If it weren't for the side effects, I would recommend Lupron. However my Quality of Life sucks. My Urologist ask If I would consider an Orchiectomy rather than Lupron. After much study, I decided that that would be the best option for me. Fewer bad side effects, And Peace Of Mind about further return of the cancer, if Lupron stop working. Decided to try a 4 month shot and see how it goes. If I'm still feeling as lousy, I'm going to continue with the Bilateral Orchiectomy. Complete body CT Scan Dec. 2014, and that will tell us if there is any other soft tissue involvement. My latest bone scan, clean, no spread to my bones. So to hold all this in tact, we may continue on with the Orchiectomy. M 69 11 months
45mg 2X O
12/6/2014
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 1  Prostate cancer Hot flashes, joint pain and numbness in fingers, no libido, shortening penis, fatigue, frequent urination at night, difficult bowel movements, hemmorhoids , fuzzy thinking Decreased my Testosterone to 3 . After prostatectomy, PSA rose to .3 and I started lupron and external beam radiation. I will stop taking lupron after current 3 month injection is over Dec 5. Waiting to see how fast the side effects disappear . M 70 6 months
22.5 1X O
11/23/2014
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 3  PMDD Hair loss, bone and joint pain, debilitating foot pain, headaches, diarrhea. F 39 4 months
3.75
10/22/2014
 4  fibroids Dizziness, hot flashes,moodiness, insomnia, .my fibroid pain went away with days if my shot. Not sure if the lupron caused it, but I had one shot to last 3 months. After it wore off in the 4th month I started having bad heartburn that I am still dealing with and none of the pills the doctor is giving me are helping. Going to see specialist. F 45 3 months
10/9/2014
 3  HEAVY BLEEDING FOR 7 MONTHS hot flashes,mood swings,severe sore rash,headaches,severe cramping pain, etc. F 51 1 years
33 1X M
9/29/2014
 2  to shut down ovaries & endo I had to go on Lupron because my body can't handle another abdominal surgery. My surgery was 8/6 and my shot was 9/12. I started my AF 3 days ago & I was laying on the couch taking a nap. When I awoke & tried to move my right leg, I had this stabbing pain in my abdomen. Worse pain in my life, well surpassing Kidney stones. Went to ER & they said it was due to the Lupron hormonal surge. The pain is so bad they gave me a script for Dilauded. If I had known I would've not gotten the shot. The pain is unbearable, but was promised this is the worst of it. Let's hope because we want to do ivf in the future & I needed to not only save my eggs but stop cysts & Endometriosis from regrowth. F 40 1 weeks
1 inj
9/26/2014
Email
 1  fibroid Lupron is poison! Severe migraines, very bad rash on hands, depression, can't keep my eyes open, joint pain in hands, trouble breathing. I've been healthy never had any of these symptoms. I've been a marathon runner this is very scary and the doctor, Larry Hess, never told me a thing. F 45 3 months
3 months
9/23/2014
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 3  advanced prostate cancer 1 days
9/18/2014
 3  Prostate Glesson score 7 Minimal hot flash symptoms--some dizzy moments and shortness of breath it is too early to tell so my giving a rating is way too premature... M 79 5 months
40MG?
8/23/2014
 1  t2 prostate Cancer Continual hot flashes and very low testesterone M 66 1 years
not sure
7/6/2014
Email
 2  Before having a myomectomy I had only one shot before a myomectomy and I didn't feel any symptoms the first 2 weeks, then I had heavy muscles pain. Then nothing much... then 7 weeks after the shot I had hot flashes and difficulty sleeping. I am loosing my hair in a scary way too. I regret taking the Lupron shot. F 47 120 days
3.75MG 1X O
5/22/2014
 5  peri-menopause hemorraging Lucky: NONE For me this has been a life-saving miracle drug! After 4 visits to the E.R., 3 blood transfusions, 1 ambulance ride and 3 EKG's my body simply couldn't take any more blood loss. I had to wait 6 weeks for my hysterectomy because I had to let me body get off the birth control pills which have a blood clotting agent...blood clots can kill you during surgery. One shot of Luperon and no more bleeding! Am on 3rd week with no side affects. I pray it lasts for 6 weeks until I have my surgery on June 2nd. F 53 1 months
? 1X M
5/16/2014
Email
 1  Endometriosis Muscle aches, bone aches, migraines, peripheral neuropathy, bone loss, blurred vision, depression, anxiety I took lupron over 3 years ago and still suffer daily. I continue to have whole body aches and pains and there are days I feel like I am 95. I have a college degree, worked a full time job 12 hours a day prior to these injections, now I am on disability. This drug has ruined my life. F 43 9 months
1X M
5/4/2014
Email
 1  Endometriosis Barely sleep at night, hot sweats day and night, depression, anger and headaches. F 32 3 months
3/24/2014
 1  prostatr ca Spent 6 months in psych lock down M 66 3 months
3/17/2014
 1  endometriosis I could barely walk..hot flashes no sex drive no pain relief loss of hair weight gain...divorce..due to mood swing depression anxiety...i was never like this before..and I also was not informed that it was chemotherapy.... F 25 6 months
2/28/2014
Email
 5  PMDD mood swings/depression (but only during the first 2 months) - then mood improvement hot flashes This drug has dramatically improved my quality of life. It has saved my life. It's important to read up on it and to know what to expect before you start - your doctor may not tell you. A very important thing to know is that things will get worse before they get better. Any hormonal symptoms will get worse for the first two weeks after the first (and often 2nd) shot. There will be periods of significant, serious depression during the first month or two. They are terrible, but short lived, only a few days for me. By month 3 I didn't have any of the mood swings, my hormonal symptoms were gone and I feel better than I ever have. F 47 5 months
shot 1X M
2/23/2014
Email
 1  prostate cancer everthing you can think of M 1 years
45mg 6X day
12/11/2013

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