LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  pelvic adhesions, edonmetriosis Mood swings, hot flashes, fatigue, joint ache, I felt 50 at 30. Very tiring. I went through years of pain went on lupron hell for 18 months only to be pain free for 25 months. I was told to repeat Lupron and did not want to. I went to chiropractor for something else and had several adjustments and was informed maybe this would help with the bladder and female organs. I thought yeah right. I am here to tell you I am pain free now and a true believer. Before trying Lupron try a chiropractor it has less side effects. F 35 18 months
1/17/2008
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 5  to stop bleeding, shrink uterine none Feeling better than i have in a long time. Better mood, more energy, more focus. Afraid to go off of it. F 47 3 months
1/16/2008
 5  Endo - severe even after surgery trouble sleeping normal 8 hours a night down to 4-6 hours. I had systemic rhem arth (JRA) prior...with no impact on my bones or joints from Lupron. I also had migraine before with no increase while on Lupron. It is a great medication for severe Endo. Worst part is when you have maxed it out and have to go back to being in pain. Nothing compared to the relief I got from Lupron. I will forfeit a couple of hours of sleep as long as they are pain free hours. Good Luck, and like eveything in life...try it for yourself. F 33
1/16/2008
 2  Endo Hot Flashes, Night Sweats, Depression, Sensitivity to Sounds, hair loss, Muscle pain, and acne I had pain in my lower pelvic area for two years(age 15-17) before FINALLY having a lap surgery--suppose to be out for only a few days, I did not leave the house for a week and a half. It was the worst pain I had ever gone through. I went back on birthcontrol for two more months then decided to try Lupron, to increase my chance of having Children later in life. The lupron made me awfully sick--The first time I was out a few days, but the second shot I was out a week. Luckily it got better the 3rd shot--only out a day. In a few days is my 4th shot--and I can't decide if i truly want to take it. I feel that my whole life has changed in the last few months--before I was the happiest high schooler ever(homecoming queen, class officer, appreciative girlfriend, all american girl)--now i feel like i never smile and that I dislike more and more people everday. I know that the lupron is probably helping me, but I'm not sure if I can do this much longer. The pain is much worse while I'm on the m F 17 3.5 months
1/13/2008
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 1  OVARIAN CYSTS bone & joint pain, neuropathy, osteoporosis, osteoarthritis autoimmune disorder, chronic fatigue, unable to sleep because of the pain This drug should be known as "THE DRUG FROM HELL". It has ruined my life since taking 2 injections in 2003. The best part is that not one doctor will believe that Lupron is the cause of all my problems. F 47 2 months
1/12/2008
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 4  Post-op for endometriosis and cysts DON'T LET THESE POSTS SCARE YOU. It's been bad, but different for everyone. So, if you and your doctor think its best for your overall health, it is definitely worth the temporary misery. I'm going on my 4th shot. I have hot flashes/ night sweats allllll the time. In fact, I'm having one right now. I mean, it's the middle of winter and I have to wear a tank top or t-shirt under a hoodie, for those times when it gets unbearable. I feel a little less focused, more emotional and irritable. I had some vaginal dryness for about a month, but that has subsided for the most part. I find all of this easier to deal with if you constantly remind yourself that it's just the drugs taking over, its worth it, and you're not normally a total basketcase. Sometimes, that doesn't work! I'm not gonna lie, it sucks ass. But even though I really hate the side effects of lupron, I'd do it all over again if it meant I could be healthier and have children of my own someday. :) F 22 3 months
1/10/2008
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 1  Endometriosis, Ovarian Cysts MEMORY LOSS, SEVERE JOINT PAIN, ABDOMINAL PAIN, NEURALGIA, WEAKNESS AND NUMBNESS IN HANDS AND FEET WITH SEVERE SWELLING, MIGRAINES, DEPRESSION, OSTEOPENIA, URINARY PROBLEMS, YEAST INFECTIONS, SEVERE HOT FLASHES, NIGHT SWEATS CONSTANT PAIN AND FATIGUE IF YOU ARE CONSIDERING USING LUPRON RESEARCH.... RESEARCH THERE ARE MANY, MANY SITES WITH WARNINGS... RUN FAST AND ASK FOR DIFFERENT SOLUTIONS... A GOOD DOCTOR WILL HAVE OPTIONS. THEY TELL YOU THESE SIDE EFFECTS ARE TEMPORARY ...THAT IS A BIG LIE.. I AM 7 YEARS LATER AFTER USING LUPRON AND STILL HAVING THESE PROBLEMS. AND TO TOP IT OFF IT DIDN'T EVEN HELP MY ENDOMETRIOSIS. FIRST I HAD 4 LAPROSCOPY'S, THEY DIDN'T HELP THEN I HAD MY RIGHT OVARY REMOVED FOR CYSTS. AFTER THAT I HAD TO HAVE A FULL HYSTERECTOMY. WHAT HELP DID THIS DO FOR ME? I WAS NEVER EVEN TOLD OF THESE SIDE EFFECTS, AND THE ONES I WAS TOLD ABOUT WERE SUPPOSED TO GO AWAY! WHAT A BIG FAT LIE!!!! I AM WORSE OFF NOW THAN I WAS BEFORE THIS I HAD ENDO, BUT NOW MY PROBLEMS ARE TOO NUMEROUS TO COUNT...PLEASE RUN HARD AND FAST AWAY FROM THIS POISON ** XX F 38 12 months
1/10/2008
 2  Endometriosis Hot flashes, depression, joint pain, exhaustion, loss of appetite, irritability, night sweats, mood swings, headaches, severe mood swings I'm about to go through my SECOND trial of this. I can't say I wouldn't recommend it at all, but I was absolutely dissatisfied with it. I was 16 when I started taking it. It made me miserable, but it eased my severe pain I had been having since I was 13. It worked for 10 months, and now I'm in the same hole, and the pain is even worse. If you ask me, all the side effects aren't even worth it. I absolutely don't want to go through this again, but it's this or surgery. It made me absolutely miserable, though, and just leaving the house was like a chore. I had to leave school and do a distance learning program. Not really worth it, if you ask me. F 17 6 months
1/9/2008
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 2  Endo Terrible mood swings,depression,emotinally unstable,depressed,severe dryness, severe joint pain,insominia I was diagnosed with Endo when I was 32 it was already stage 4+,after exploring many options none of them really worked. I was also informed that a hystorectomy was too high risk as I would end up with a calostomy for life due to so many adhesions on to my bowel and other organs. As a result I began a 6 month regime of lupron injections. Though I was informed of the risks on paper to live it as another matter!!! I hate how it made me feel and the negative effect it has had on my relationship with my husband. I would not wish these syptoms on anyone!!! I am scheduled to recive my 3 needle next week and I can no longer do this to myself. Though some of the pain is better the side effects are worse than I ever imagined!! My quality of life has been so dramatically been reduced that I have a hard time to get though most days at work and feel like I crumble when I get home. After reading the shared experinces/effects from others on this drug it terifies me to continue. As a result I am not F 41 2 months
1/7/2008
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 1  Gleason of 6......PSA 5 ?????? Hot Flashes..Shoulders and hips ache..Weight gain...Slow urination...Can't sleep without (Zanax) sleeping pills...Up every 2 hours urinating...Its been a 5 weeks since I got shot..and 4 week since seed implants....They treated me with 2 different Cancer treatments for very small amount of cancer.... I have all kinds of problems now.. Live in Il.... In Florida for winter..Went to Highly Refered Doc in Fort Myers...After Biopsy had one of 14 Positive for Cancer...Got seed implanted..But a week Before Seeding...Dr gave me a 6 Month Lupron Shot??? I have no idea why.....I should have looked into it before...To late now..Making me Miserable...That shot is for advanced prostate cancer Patients..I wonder if he treated the wrong patient in the wrong room.....Would never advise anyone to get that shot unless it was the last resort...For advanced Prostate Cancer...I think Dr.Screwed me up... M 77 5 weeks
12/29/2007
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 1  Endometriosis Severe bone and joint pain; memory loss; mood swings; hair loss; tachycardia, chest pain; nausea; weight gain; edema. Bone pain persists months after stopping Lupron People should read a lot before risking their health with this drug...you can end up feeling worse than you ever did with endometriosis. Besides, after the drug wears off, the endo symptoms come back with a vengance. This drug is not worth 6 months of menopause. F 36 6 months
12/28/2007
 4  IVF I really haven't had any. Maybe a little hot flash once in awhile. Other then that, its been great. I was scared to start this since everyone keeps talking about the side effects, but I haven't had trouble. If I did though it would be well worth it to have a baby. I will do anything to get a bundle of joy. F 28 22 days
12/26/2007
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 2  Advanced prostrate cancer Severe hot flashes, severe muscle pain, joint pain, abdominal pain, bloating, constipation, depression, loss of libido, shrunken testicles and penis, loss of ambition. I am on my third and last shot of Lupron (one four month dose and two one month doses). I will say the Lupron reduced my PSA from 125 to 0.4. However, now I am trying alernative solutions to my prostrate problem. At present, 12-18-07, I am taking Chinese herbs, applying nutrition and praying, hoping to cure my cancer. If, in the future I need to take drastric measures to control the cancer, I will elect for physical castration rather than go back on Lupron. Good Luck to all of us...Curtis ( P.S.: I am looking for a source for "PC Spes". If you know of such, please contact me: [email protected].) M 66 5 months
12/18/2007
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 4  fibroid-pre-hysterectomy surgery Been on injections for a month now-stomach has went down somewhat-no hot flashes-my most noticeable change is I get in a very high 'happy' mode and I have tons of energy and can't shut it down. My next injection is in a few days, maybe the symptoms will get more severe the longer I am on? (3 month treatment) I felt I had to give this drug a try. My doctor didn't even want to do my hysterectomy until the fibroid was smaller and my uterus had shrunk. F 41 1 months
12/17/2007
 4   Severe endometriosis, ovarian cysts, serious menstrual pain I went on Lupron almost 6 years ago. I was desperate and the alternative for me was a complete hysterectomy. I had grave concerns about the side effects, but felt I had no choice. I was already infertile at 36 due to endometriosis and cysts. Here is my experience: The shots put me into drug induced menopause within about 3 weeks. I wish I had been more prepared for what that meant. I would have felt more in control if I had known what to expect. By the second shot, I was experiencing moments of intense depression. I could sit and cry for no reason. Never, had I dealt with this before. After the second shot (I'm experiencing full menopause/hot flashes etc by now) I started having serious joint pain. So bad, there were days I could hardly walk. I was only able to complete 5 of the 6 shots. I simply could not cope with the last one. After about a month, my period started and the joint pain and menopausal symptoms gradually declined. I was so upset when I still had pain during F 42 5 months
12/11/2007
 2  Post-Laparoscopy Therapy (Endo) Hot Flashes-Night Sweats- Insomnia- Always Felt Hot- Irritability- Anxious-Depressed-Abdominal Tenderness and Cramping- Fatigued- Loss of Appetite First 2 weeks after shot felt great- week 3 and 4 started to feel irritable and have hot flashes and night sweats- felt exhausted due to insomnia and lack of sleep- week 5 and 6 were the worst-abdominal pain/cramping for 2 weeks, very intense hot flashes/night sweats and very emotional/ irritable- week 7 almost like clockwork/over night felt back to normal, abdominal cramping gone, sex drive back to normal, emotionally stable, hot flashes substantially diminished. My advice if you have endometriosis like me- have surgery- which I did. That is the only real way to get rid of the problem. Lupron used post surgery for therapy to allow body to heal and to not get a period/inflame any endometrial cells that may have not been removed with surgery. If you don't have to go on this medication do not. It is a very very uncomfortable drug to be one. Makes you want to crawl out of your skin. Alternative therapies/drugs should be considered. There is nothing more unnatural for your body than to go F 30 1 months
12/3/2007
 2  Endometriosis night sweats, hot flashes, fatigue, severe abdominal pain, insomnia I read comments on this site before getting my 1st shot about 3 weeks ago; not only was I having doubts due to the cost (even WITH insurance, it's still expensive)but the uncertainty of it even working with horrible side effects made me all the more skeptical. Well, I wasted 1 month's worth of $$ and that will be all! The pain I've been experiencing in my abdomen after the 1st week is I think worse than the endo! I have to be in the fetal position most of the time to get any "relief". I can't sleep and I'm SO tired so I can't concentrate at work either! I wouldn't tell anyone not to take it, there are some people with positive experiences; try it at least once and see how you do. F 30 20 days
11/30/2007
 1  Endometriosis weight gain(primarily in the belly area), hot flashes, memory loss, severe depression, anxiety, lack of concentration, tingling in hands and arms I had the laparoscopy procedure Nov 2006. After that the doctor suggested Lupron for 6 months. The first two months I experienced really bad hot flashes but then the depression and anxiety kicked in. I had suicidal thoughts(no history of this before), so the doctor put me on Wellbutrin and Ativan. The Wellbutrin made things worse. I completed the 6-month treatment in June 2007 but I continue to have problems with anxiety, depression, and memory loss in Nov 2007. The pain has gone away but I don't think it was worth it since I have all these other problems now. I would really think twice about using this medication again. F 38 6 months
11/28/2007
 3  Fibriods Bone and Joint pain. Loss of Libido It is very hard to read these descriptions of side effects that other women are having. I am very lucky since I have only had some bone and joint pain which has now subsided. This website worried me more then necesary. It really wasn't that bad. The loss of sex drive is a bit bothering but the pain from the fibriods will make up for that once they are all gone. Good luck to all and ask you Doctor any questions you may have before making your own decisions about this drug. Don't make a decision based on just these side effects that others are listing here. I talked to several women who took Lupron and they did not have side effects that were very bad at all. F 28 6 months
11/19/2007
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 2  Endometriosis Severe mood swings to the point of aggression. Some hot flashes and night sweats. Main thing was the horrible mood swings I had to go thru. My mood swings and attitude got worse and worse as the days progressed, had to to get meds to help try to calm me down. My fiance' and I almost called off our weddding b/c of my roller coaster of mood swings. F 24 2 months
11/14/2007
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