LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  intestinal endometriosis at first: mood swings, occasional hot flashes, extreme fatigue now: Hot flashes every hour, zero sex drive, dryness, fatigue Despite all that, I am virtually asymptomatic for the endometriosis. I have had 2 "attacks" since I started and none of the usual bowel issues at all that I had regularly for 15 years. F 37 3 months
12/27/2009
 5  Endometriosis hot flashes, weight gain Took years to decide to got on this med, but it has helped me lead a normal life. Before going on lupron I missed at least 5 days from my work and social life each month and was on multiple pain killers and opiates each period. Add back therapy (estrogen and progesterone) has assisted with hot flashes. F 39 1 years
12/20/2009
 4  severe endometriosis hot flashes, water retention, wt gain, very fatigued, very nauseated, joint pain, emotional 2nd time on lupron. 3month injection 5 weeks ago, surgery in april. increase in endo symptoms for the first 2 weeks - more pain, etc, but no other side effects. now i don't have any abdominal pain. however, i have terrible hot flashes all the time, i am either very nauseated or very hungry, my joints hurt and i have a continuous headache. butlast time i used lupron i had the same side effects and i was pain free or had minimal pain for 5 years after the last injection. F 26 5 weeks
12/14/2009
 4  Part of IVF treatment Miagranes increased. SEVERE joint point pain, especially in my ankles. The worst acne since I was a teenager. Bloating. Increased crying. The only reason I took this medication is because it was part of my in-vitro fertilization protocol. It's been a rough 25 days & I just did my last injection tonight. F 37 25 days
12/13/2009
 3  Ovarian cysts Very bad mood swings,pain in my stomach, and headaches I started noticing side effects within 16 hours. I have the worst mood swings, within a 45 min period I went from crying to yelling, back to crying and then fine. I am having a realy hard time with it and I am supposed to take this for 3 months. F 34 4 days
12/13/2009
 3  yes vaginal dryness,weight gain and fatigue I took my first and only 3 month lupron injection 3 weeks ago.I have no complaints my doctor precribed me aygestion to offset some of the side effects of the lupron which has done it's job! I have also been taking multi vitamins everyday which he also suggested. I go to have my partial hystorectomy on dec. 28. F 39 18 days
12/4/2009
 1  Fibroids Took one 1 shot of Lupron only, in preparation for minor fibroid surgery. Six weeks after the shot and three weeks after the surgery, I became bloated. I am still bloated four months later. Has anyone had this experience? I am miserable. F 45 1 months
12/4/2009
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 4  severe endometriosis some weight gain, and my back hurts sometimes,no hotflashes i got the lupron shot the first week in august,after having surgery for a 8cm mass that was pushing my uterus over after i had surgery i found out that i had endometriosis..thank god i already have a child because the doctor said it was pretty bad, started my period after surgery,as soon as i got the shot my period stopped immediately,but i spotted every day up until i got my 2nd 3 mth(just enough to wear a pantyliner) and last shot the beginning of this month,no spotting since..i got up until febuary and i'll be finished..so i just hope when i do get my period again they are mot as bad as before because if they are i have to get a complete hysterectomy,im just going to pray about, cause lord knows i cant go through with the pain again, it is just unbearable! i say do your research because i was hesite about trying it but it has helped alot,no periods which are a plus! side affects were bearable for me so far! good luck i got 2 more months will keep posting updates F 31 4 months
11/30/2009
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 3  Severe endo and adenomyosis fatigue, anxiety, depression (better the third month), hot flashes, night sweats that cause a lot of sleep disruption, bad short term memory. 3 months into it aged facial skin and fatigue are the worst remaining side effects. Copious bleeding and worsening pains led to a terrible anemia. It was hysterectomy or this. Have been put on the Mirena IUD 2 weeks ago, the idea is that it begins working while the Lupron is still stopping the bleeding. (The Mirena alone can cause worse bleeding the first month or so). If this works, the Lupron gets completely flushed out and the Mirena leads to minor bleeding and relief until real menopause - it's been worth it, as I cherish keeping my uterus. However, the side effects the first 6-8 weeks were awful. I am juicing, taking B, C, D and calcium supplements but would love to know what else can be done. Will the aged skin go back to normal? F 41 3 months
11/30/2009
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 3  endo, chronic pelvic pain from it 1st month, spotting and a bit of depression. 2nd and 3rd month minimal spotting. Hot flashes within the first 7 days of tx. Sleeplessness, fatigue, forgetfulness (more so than usual, i think?), hair thinning, weight fluctuation, still chronic pain. Some endo relief. I am not sure having a copay of 122 bucks per injection was worth it. Was put on high doses of pain pills (which i dont like to take) before & during the inj. I was a hyper person, & have noticed I feel a shell of myself. Pristiq made me sick, but another anti depression, Cymbalta, helped a little in the 30-60mg range. Last inj was around Halloween. I hope to persevere & be able to function again, & to lose some weight around my middle. I doubt i will get my 4 pack back, but at this point if i lose the tire around it, I will be happy. I am good for about 3 hours now if i go out, as long as it is not strenuous. Before and during the first few inj, I could not handle an hour. F 34 6 months
11/29/2009
 4  Very severe endometriosis Mood swings (I cry a lot now), depression, some memory loss, hair loss, hot flashes and night sweats, some joint and muscle pain I originally saw a doc about blood in my stool during my periods, which were absolutely horrible (But women are supposed to shut up and take it, right?) Turns out that I had a ever growing endometrioma that was obstructing my large intestines and my left ureter. Also, the endo was causing my appendix to obstruct another part of my intestines. I was (what felt like) rushed to surgery, had two sections of my intestines removed, endo cleaned up, and my appendix removed. I was given the 3 month shot of Lupron when I left the hospital, and I took my second three month shot about a month ago (I am scheduled for one more). The mood swings are rough, but doable, especially if you have an understanding support system. The hot flashes aren't fun. They put me on add-back therapy for a couple of weeks--Loestrin, in fact--which made me spot for 6 weeks, as well as make me feel as though my body was trying to have a period (though nowhere NEAR the kind of periods I use to have). The first shot of Lupron did not cause me to spot, so the docs took me off the add-back, so now I am just toughing it out. I feel much better these days, though it's hard to work out whether it's the Lupron or the surgery. The Lupron is very expensive, which could prevent some from finding relief with this drug. The spotting is annoying, and the hair loss makes me a little sad, but I'm hoping that none of this will be temporary. The best part about Lupron: no periods. F 29 4 months
11/27/2009
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 3  Endometriosis Mood swings, hot flashes, vaginal dryness,feeling achy all over, and Im still not the same and I have been off it for 3 months. I was on the shot for 6 months and the side effects were rough to deal with. I have started my period back and I am hurting the same way I was before. F 22 6 months
11/26/2009
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 1  Endometriosis Weight gain, hot flashes, back and neck pain, joint and tissue pain all over, sesitivity all over, stiffness, fatigue. Well, it's 2009 and I am STILL suffering from horrible side effects from Lupron taken in 2005! I have been to all kinds of specialist to try and find out how we can treat all my symtoms. Somehow Lupron changed my body after the 1st of 3 three shots. I can't find a doctor who will take the time to research this and all my testing has come back negative. My next appointment is with a Lyme Disease Doctor. In my opinion, Lupron was NOT worth the side effects and didn't solve ANY of my intials problems either. Still have endometriosis and can't get pregnant! F 34 6 months
11/23/2009
 4  Prostate Cancer Very sleepy and fatigued at different time periods of the day, especially after eating.Weight gain (32 pounds in 34 months), increased appitite, cold & hot flashes,some insomnia, irritable Upon turning 50 my PSA WAS 53.6 and was diagnosed with stage 3 prostate cancer with a gleason score of 9. I recieved lupron and casodex for 34 months and 10 weeks of external beam radiation (imrt). My PSA went down to 0.02 and stayed there for about 6 to 8 months after the treatment stopped. After that it began to double avery 3 months at first, then after about 18 months it went from 6.4 to 15 in 6 weeks. I am now on both drugs again. Have been on them now for 6 weeks as of 11/16/09 and have not recieved the results of the blood test taken the other day. I am also trying MMS. Would like to find other choises as i am told my cancer is not cureable. M 50 34 months
11/19/2009
 5  Fibroids some hot flashes, but that's about it for me. This gave me my life back! I went to ER with SEVERE abdominal pain and bleeding. I had sever anemia. I had to have blood transfusions it was so low. I was given the 3-month Lupron shot and after about 1 week my bleeding totally went away and the pain was gone. I was able to go on my scheduled Caribbean Cruise because of Lupron the next month. Without it I would have had to cancel it. This is temporary until I have my Fibroids removed. Moodiness and insomnia - I had these before I took Lupron. I highly recommend it, but realize that side effects are different for everyone. F 39 1 months
11/18/2009
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 5  Severe Endometreosis None I was put on Lupron for severe Endo as a last ditch effort before a hysterectomy. I received 3 injections and it has worked beautifully - no mood swings, no hot flashes, no night sweats..nothing and the pain, heavy bleeding and bowel/bladder problems that I had from the endo are completely gone. I was hesitant to take the drug from all the negative feedback but I have to say I experienced none of the issues that others have complained of. I would recommend it to anyone with a similar problem. F 49 3 months
11/13/2009
 1  uterine fibroids hot flashes, vaginal dryness, all the little things they warn you about. THE MOST IMPORTANT THING THEY DID NOT EMPHASIZE WAS RESULTANT OSTEOPOROSIS!!! Do not take this drug. It is poison to your body. Do your own research, find a doc who will work with you. If a doc suggests Lupron, for any reason, to any person, man or woman, run, run, run! The problems you will deal with later in life because of this poison, are far worse than the symptoms you are treating now with Lupron. If you have already received the injections, start taking calcium and vitamin D now and don't stop. Also, get a bone density scan done! Every two years if you are found to have osteoporosis. Good luck to all who have become Lupron Victims. F 49 3 months
11/13/2009
 4  endometriosis during treatment: constipation, hot flashes, acne, sleeplessness Before Lupon, I had terrible nausia and cramping with my period. It was so painful I ended up in the ER twice. When I first got the shot, I was really sick and constipated an nauseated for about 2 weeks, during which time I was TERRIFIED at the thought of having this medication in my body for another 3 months. But it went away... and I felt FANTASTIC. I could go out with friends, go on vacation, make PLANS that did not hinge on the condition "...if I feel okay that day." My major side effects during that time were acne and sleeplessness. In fact, I did not sleep through the night for 6 months. THAT sucked, but was nothing in comparison to the relief I felt. Towards the end of the first 3 month shot, I started bleeding... and I bled for 5 weeks. I had to do estrogen add-back to get it to stop. The second 3 months shot was not as blissful, but I still felt a lot of relief. Again, when it started wearing off, I started bleeding, but that was only 8 days. It has now been a month since the shot wore off, and I still have some strange things going on. I am really tight in my abdomen and vagina. It is getting better, but it was painful at first. I had a headache for a few weeks that would not stop. That has gone away. Right now, I am having hot flashes. I think overall, my hormones are still just trying to adjust. We will see what happens! No matter what, I AM glad that I did it and had that 6 months of relief from my pain. Did anyone continue expe F 28 6 months
11/12/2009
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 3  ER positve Breast Cancer I am taking Lupron as part of the Hormonal Treatement plan instead of taking Tamoxifin. Lupron as put me in "menopause" and enables me to take Arimedax for Post menopausal treatment. I have received the Lupron injections since 9/2005 and have no periods since. Would prefer not to be on this med as I am very concerned about the 'long-term' effects. Pros: no periods, No Breast Cancer!! Cons: weight gain especially in the mid section, water retention, insomnia (very bad), joint aches, back ache, hot flashes, and real difficulty with an exacorbation of depression with irriatability, low mood, some mood swings, impatient. This has been the most difficult piece with this medication. You really have to weigh the pros and cons as it can become a quality of life issue. For me it is Lupron with Depression symptoms and knowing that it is not likely that my Breast CA will return or stopping the med and concern of a reoccurance. F 35 4.3 years
11/12/2009
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 1  endrometrios It was the worst, I experience the worst side effects that any medicine should be allowed to have. Extreme mood swings, Intense hot flashes and night sweats frequently, extreme weight gain(15 lbs)within 2 months and still trying to lose it...hair loss and foggy mind. I went to my general practioner and he described Wellbuton to counteract the Lupron. I will deal with the pain when ever my cycle resumes. M 44 3 months
11/12/2009

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