LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  endometriosis In the beging I had hot flashed and some mood swings. I had a lot of other side effect but due to a fall it was blamed on the fall. However 11 months later I have a microadmea in my pitubitary gland, a 3 mm tumor. It is not cancer however I am now learning it is because of the Lupron shot. I have over the last 11 months had memory loss that has gotten worse each week, hot flashes, cold sweats, low tolerance to cold weather, inablity to tan, heart paplations, tacardia, insomia, endma, joint pain, sever headacheds, no desire for sex, blured and double vision, lacation, bone pain, tingling in hands and feet, depression, anxity, nervous, delusions, and very very fatigue. Granted the Lupron worked wonders for the endometerisos! I had a period 3 weeks after taking the shot. My doctor told me it would be a bad one but it was very light compared to others. I have had a period now in 11 months. Yeh I had some spotting off and on but very little. The pain I was in with my endo was ve If you do not have children and wanting to have children and have endometriosis Lupron is a good tool to give you more time if used in small does. I did both the one and three month shot. the one month shot works better. The three month shot started wearing off in about 2 1/2 months. F 33 11 months
9/21/2007
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 1  Severe Pelvic Pain, constant bleedn EXTREME Bone and Joint Pain (been to ER twice since it is so bad...and P/C doc will not prescribe percocet for "knee pain" - Dr. Obudo-Ecklad of Kaiser Fairfield, CA), crutches barely help. Sleeplessness, Hot Flashes, added depression, weight gain, bloated. The bone pain is so bad though, that at times at night I have to get on the floor and use my upper body to drag my legs to the bathroom! After 2 grapefruit size dermoids were removed from inside ea. ovary every period thereafter was worse then when I had those cysts. My periods last 1.5-3wks. Only treatment (besides B/C pills that did not help) has been Lupron from 1.5yrs ago until now. This summer I bled 5.5 out of 6.5 wks so I caved and took a 1 month supply. NO NOT TAKE THIS DRUG. My bone and joint pain is so bad that using crutches barely helps, I have to take percocet just to ease the pain. Added Depression, sleeplessness, hot flashes are all happening. My bone pain happened within hrs of the injection. Before getting it I told te GYN I didn't want it since other proclaimed their bone pain was unbearable, he (dr. Nystul, Kaiser San Diego)said I would NOT get that side effect since I was so young. Well guess he never takes the time to look on forums to see that about 18 out of 20 women are miserable from this drug and share similiar side effects. Worse part, the tiny side effect booklet says it can be IRREVERSI F 27 1 months
9/18/2007
 3  Endo Hot flashes, headaches, dizziness, fatigue, loss of sex drive, and much much more. I am 3 months in. I still get my period each month-- like 3 times a month. I guess my cramps are gone but goodness I want these side effects to stop. F 21 3 months
9/14/2007
 3  Endometreosis Severe migraines, initial joint pain, went away after 2 weeks, gained 20 lbs I took 2 3 months shots after I still experienced abdominal pain AFTER a hysterectomy and 2 exploratory surgeries. It stopped the abdominal pain, which was/is severe even after removal of my uterus & ovaries, but pain came back after treatment. F 34 6 months
9/13/2007
 4  Unexplained Infertility/Pre IVF sreious hot flashes/night sweats; bloating, FATIGUE taking 10 units nightly for 18 days F 39 9 days
9/12/2007
 2  Endometriosis Terrible headaches, hot flashes, unable to sleep at night, always tired, bone pain I have been on this drug for a week now and since the day after I got it my head has been throbing everyday. During the day I'm extremely tired, and at night I toss and turn all night because even though I have the air on 70 and my fan on I constantly get hot to the point where my body is hot to the touch. I haven't had the cramping that I'm used to having so thats good I'm just a little scared that these side effects aren't going to get better. They have only progressed. I have pain in my neck and knees..WHAT SHOULD I DO? F 23
9/12/2007
 1  Shrink fibroid pre-surgery Inability to sleep, dizziness, SEVERE bone pain in legs & arms, depression and mood swings. This medication has had a major impact on my life. I'd much rather have the pelvic pain and heavy bleeding, than feeling that I no longer have control of my life. it's so bad that I no longer trust my on judgement. I'm do for my second shot in a week. I don't think it's going to happen. F 36 7 weeks
9/8/2007
 3  Fibroids This Friday will make three weeks since I was given Lupron. I have had very little side effects so far; since been on Lupron I have had a mild headache, some nausea (nothing to bad), I have noticed that at night my joints hurt. Overall I have not had the bad side effects that some people have reported. I can't said whether or not Lupron is working in my case. My doctor said he gave me to shot to stop my periods to relive my anemia; Since receiving the shot I did get a period that was just has heavy as before. I guess I will have to wait until next month to see if my period stops. F 34 20 days
9/5/2007
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 3  prostate cancer Hot flashes, sweating, total loss of sexual desire, fatigue. Taking Lupron to shrink prostate in order to receive seed implants. Hot flashes are annoying, but tolerable. Fatigue just causes me to slow down some. Loss of sex desire not a problem. I exercise regularly and walk a lot, which I believe reduces side effects. After 4 months of Lupron (plus a daily dose of Casodex pills), I hope to be ready for the implants. M 79 2 days
9/3/2007
 5  Amenorrhea First two weeks after first shot, pain was worse but then it went away and has NOT been back. Hot flashes, night sweats. After I got passed the first 2 weeks, Life has been wonderful with no PAIN! Hot flashes and night sweats are not pleasant but NO pain! I have lost 4 inches around my lower abdomen since starting the shots. Even with the night sweats and hot flashes, I think this was the best thing for me. I just hope the pain doesn't come back once the shots stop. F 43 4 months
8/30/2007
 3  Gestational Carrier Hot flashes, leg back cramps, my stomach is rock hard and bloated!, Drowsiness, lack of energy, mood swings, I am doing this because I want to give someone the best gift I can. I am worried about my bloated stomach! It looks like I am 6 months pregnant when I'm not at all yet!! I haven't gained any weight though so it is stange F 29 1 days
8/30/2007
 3  Total Androgen Suppression Minor hot flashes, zero sexual response, shortening of member. I have not had post-IMRI PSA test yet. While I am aware that many men have disabling side affects, I have not found that to be true (yet) in my case. I had my second four-month injection about two months ago. The lack of libido I find satisfying as it has released me to concentrate on other matters that are important to me. While I suggested to my wife that I was ready to discontinue it, for her sake, she has asked me to continue to receive it for the two years recommended. The shortening of the member is significant (all of a sudden I have a foreskin problem that did not exist before) but I will have to wait and see if it is disabling in any way. All in all I consider myself very lucky in experiencing a minimum of side affects and am leading a successful, meaningful life. M 73 6 months
8/30/2007
 3  endo and awful cramps I am just wondering if anyone is having awful back pain while on Lupron? My back is killing me. F 36 4 months
8/29/2007
 5  endometriosis NONE I have had no problems with this drug, only wish I could stay on it until menopause! I feel happy, and energetic without hotflashes or moodswings-wonderful!!!!! F 41 3 months
8/27/2007
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 3  stage iv endo hot flashes, hair loss, dry skin, depressed mood, insomnia, vaginal dryness I was leary about taking this drug, but I was not able to take the pain anymore. I took the three month dose in one injection to decrease the inflammation before surgery. Three days later I started my period (after having it a week previously) and had the usual pain. Overall besides the common side effects such as hot flashes and moodiness I have been happy with what the drug has done for me. I am now waiting for the return of my period to see if my surgery was successful in resolving some of the endo pain. Do your research though, this drug is not for everyone. F 39 3 months
8/27/2007
 3  Endometriosis Hot flashes, dry vagina, lack of interest in sex, Mood Swings, 5 week period at beginning I went on Lupron for the first time when I was 15 and it was okay. Mainly I was moody, and irritated by most people in my life more than half of the time. After 6 months of treatment, there wasn't much of a change. I still had endo and was waiting as long as i could handle the pain before another surgery. I Just recently got another surgery and started the Lupron again 2 months ago. so far i had a 5 week painful period which just ended but no other side effects yet. I am reconsidering taking the second dose. F 20 7 months
8/23/2007
 3  Endo & Fibroids Pre Uterine Ablatio Lack of energy, mild depression, and most recently joint pain and weight gain. I have not had the side effects that the Doc mentioned such as hot flashes, lack of libido nor dryness. Have to take for 5 months (was supposed to be four pre proceedure, but secry messed up booking the proceedure date). Have two more shots to go. Have family hist. of Uterine Cancer, so far so good with me in not getting it, but still had the fibroids and endo. Want a hysterectomy, but in Canada, no one will do it unless you are cancerous. So Doc has talked me into the Uterine Ablation. I think so far the side effects I am having are outweighed by the fact I have a cessation in periods, discharge, pain and serious mood swings. If this, in partnership with the ablation do similar to that of a hysterectomy with out kicking into early menopause...I think it will be ok..some of the comments on here are very scary and I feel for each of you. I don't like the achy joint feeling every day, but over the years I have learned to live with the pain of my female problems, so this is just a F 44 3 months
8/21/2007
 1  Prostate cancer Every single complaint previously listed by other males on this list. Total lack of interest in sex,(which I enjoyed very much despite my age),sweats, aching joints, change in skin texture, lack of interest in most endeavors. In addition, I have had a radical change in bowel movements, headaches when I have NEVER had headaches before, and seem to have little or no initiative or 'get up and get something done' attitude. I've also had trouble with hemmorhoids, which I have not had since my late teens, early twenties, and then only minor. Now most annoying. I have not had opportunity yet to determine whether Lupron will actually reduce my PSA numbers or not as I must wait for my next appointment with my Urologist to take PSA. Even if it does, I would hesitate to agree to being injected with Lupron again. It is, as one gentleman said, "Like being castrated".. I would add a big PLUS to that! M 81 2 months
8/17/2007
 3  Endometriosis; chronic pelvic pain Intense bouts of depression and irrational mood swings; hot flashes; insomnia; change in sexual sensation (not lack of mood); hemorrhaging for several hours about one week into treatment It is a scary medication - I am taking an anti-depressant as well, but I am still suffering mental/emotional effects. The disruption in sleep adds to the mood problems too. I would carefully weigh all options before choosing this route - it is not an easy one. F 31 2 months
8/14/2007
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 3  to shrink fibroid Hot flashes, insomnia, MAJOR depression, anxiety, crying jags, occasional pain flare-ups, heart palpitations I bled heavily during the first of my 3-month treatment, and had a brief bout of severe depression and inexplicable crying. Now, in my 2nd month of treatment, I had some breakthrough bleeding/spotting which seems to get worse with intercourse. I'm in the middle of a depressive episode that is into its 4th day. My doctor had expressed concern that, because I had a history of depression (which, up to this point, had been managed quite well with meds), I would be more susceptible to that particular side effect, but I was totally unprepared for the severity and quick onset. I take 450 mg of Wellbutrin XL daily for depression, but it seems to have no effect whatsoever against the Lupron. I compare it to what I imagine I would feel if my entire family died in an accident - and I were off my antidepressant, that's how devasting it's been. I sob as if my heart is broken and I have NO idea why. It's now past 1 AM on a Monday night as I'm typing this, but I'm still wide awake - I've definitely h F 46 2 months
8/14/2007
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