LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Endo Headaches, MILD confusion/memory loss, night sweats, mild hot flashes, mild sadness, mild acne & weight gain. It's only been 1 week but so far the side effects have been mild w/ the exception of headaches. They're a daily occurrence, get more intense each day. I'm on once/mo. for 6 mos., take 5 mg progestin daily as "add back". Stage 3 endo, diagnosed in Dec. Was on the pill for about 18 mos w/out improvement so doc suggested lupron. I'd actually not be too bothered by most side effects, but the weight gain, acne & mood swings. I struggle w/ my mood as it is, & w/ weight so I'm not impressed w/ gaining about 3 lbs in a week. The weirdest thing is the false 'hunger' I have. It's quite bizarre; I'm sorta hungry & full at the same time. I'll eat & be full but 30 min later get almost like hunger pangs; yet I'm STILL FULL! It's nuts! Also noticed I'm actually eating a lil' less cuz I get nauseated bout 1/2way into a meal probably 1/2 the time I eat. Haven't had TOO many hot flashes; been pretty tolerable but I've gotten night sweats & woke up SOAKED in the a.m. past couple days. Feel overall kinda tired & forgot what I was doing mid-task a couple times. Still in the stage where estrogen is actually "surging" before it drops so I guess side effects will probably intensify the next few wks. I feel awful for those who had such a negative experience but for ME so far I've noticed my pain's already reduced. Started shot 1st day of my period & it only lasted 1.5 days vs. a "normal" week-long cycle. I'm keeping my fingers crossed that ben F 29 1 weeks
1X M
2/5/2010
 1  endomitriosis I was givin lupron to help early endo. It destroyed my life. I had horrible hot flashes, extreem bone pain, muscle spasums and achs, terrible mood swings and messed up my thinking. Had short term memory loss. I still continued to have pain threw the shot, it was not good for me and i only ahd the shot once. I was on my peroid for three weeks straight then didnt have it for three months F 17 1 times
1X O
2/3/2010
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 3  Fibroids Extreme Hot Flashes; High Blood Pressure Though the bleedng has stopped after the first shot; my blood pressure has shot up to 160/90. Has anyone else had this happen? Make sure you check your blood pressure while on this drug. F 53 2 months
1/27/2010
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 1  Hypothyroidism and PCOS Mood swings- super emotional, memory loss/confusion, spacey, Treatment done in June and July 2009. It wreaked havoc on my body I haven't been the same since. I had gotten to the point where I was finally losing weight and I was feeling okay. I think I just needed to be taken off of birth control. My body doesn't like pills with hormones. Instead, I got some doses of lupron. AHH!!! Anyone know anything about lawsuits? F 24 2 months
1/25/2010
 5  Fibroids and endometriosis HOT hot flashes, vaginal dryness, dry skin and eyes, occasional night sweats. WELL worth the inconvenience and side effects, Lupron really did the trick in shrinking all my fibroids (I had about five large ones) and shutting down the endo. I had surgery first, followed by six months of Lupron Depot injections. I never had a recurrence of either the endometriosis or the fibroids. I would recommend Lupron to anyone with severe bleeding problems and for whom hysterectomy was the first solution given by a doctor. The first three doctors I saw wanted to do an immediate hysterectomy and never mentioned Lupron. The fourth doctor suggested surgery followed by Lupron -- we would have done it the other way around except I was bleeding so much that I was on the edge of not being an acceptable candidate for surgery because my hemocrit levels were so low. I, too, have chemotherapy experience from a late-stage childhood cancer -- 11 months of MOPP chemo, which was nasty indeed. The Lupron wasn't even close to chemo, not in the same universe. And the Lupron side effects are temporary, unlike chemo and radiation side effects that I'm still dealing with 30 years later. If you believe as I do that keeping your uterus intact is important (talk to older women who have had hysterectomies and many years to live with the aftereffects -- younger women won't experience as many problems), then I truly can't recommend Lupron enough. F 47 6 months
1/22/2010
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 3  Fibroids I became very emotional. Cry at a drop of a hat; have become very depressed or angry at times. loss of short term memory, extreme fatigue, joint pain. Night sweats and hot flashes; hair loss This drug is, in my opinion, a last resort type of drug. If I didn't need the benefits of this drug, I would NOT EVER take this drug again. I'm crossing my fingers that it has done what my doctor stated it would do...please because I don't want to do this again F 31 3 months
1/22/2010
 4  Endo/ Polycystic ovarian syndrome Hot flashes, cramps, short term memory loss, dryness, insomnia, moodiness, lower back pain I started the injections after my surgery for endo. I started with the monthly injections and had a heavy period at first and cramping but have not had anything since. I did experience hot flashes but very minimal. my doc had me on add back therapy which I think helped with the side effects a lot because when I would forget to take it I experienced more of them. I have notice that my memory isnt very good sometimes. But over all this drug has helped imensely and I do not regret the decision. I havent really noticed even being on the drug (except when hot flashing) and it was been nice to be without a period and pain for the last 4 months. I did have some weight gain in the very beginning and so I began to workout daily and eat better and found that I could easily lose the weight and it also helped with the moodiness. I noticed that during what was supposed to be "that time of month" I was way more moody then normal. overall I recommend this drug to anyone who would like to start controlling there periods and pain instead of the other way around. F 20 4 months
1/21/2010
 4  Endo I have been on Lupron for almost a year. I did 3 month shots for the first 9 months and have been on one month shots the last 3. At first, I had dryness and almost complete loss of sex drive - sex began to hurt and has not felt right since I started the shot. Now, I have gained almost 15 pounds and can't seem to lose it. My mood swings are worse on the one month shot. My short term memory is very bad. I have even wondered if I am experiencing early signs of Alzheimers. Lupron has helped tremendously for the pain and bleeding. I have zero pain and have not had any spotting or bleeding. Basically, horrible memory loss, low sex drive, dryness and pretty bad mood swings. I would recommended this drug as a last resort before having a hysterectomy; however, it does work for the pain and suffering of endo. I feel like it can be handled as long as you know what you are getting into and possibly take an anxiety drug like Prozac to help with the mood swings. A healthy diet and daily exercise helps a lot, too with the weight gain. F 30 12 months
1/20/2010
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 4  Endometriosis At first I had a stuffy nose, headaches, sleeplessness, mood swings, (sore throat?), and extreme thirstiness. Only on my first month.. I only started it a week ago but so far I am only experiencing cold symptoms. My doctor said it might make the pain flare up worse until the third month but it was a last resort. So far I would say go for it. F 17 7 days
1/19/2010
 3  Severe Endometriosis Very Moody! Very heavy breakthrough bleeding, joint pain, Bloating and headaches. How long is the breakthrough bleeding suppose to last. I am going on my thrid week. F 41 3 months
1/19/2010
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 2  Stage 4 Endometriosis Hot flashes, night sweats, chills, severe fatigue, depression, loss of interest (in sex and pretty much everything else important to me), weakness (in general), bleeding and pelvic pain I have only received (2) injections over a two month time span. After the first injection, I became very weak, tired and depressed and bled for two weeks non-stop. I could not even muster up enough energy to make phone calls or to properly care for myself. I am only a few days into injection number two and my symptoms have change a little. I am very fatigued and feel as though I could sleep for day, however, have insomnia. I am hungry but too tired to cook. I sweat so much that I have chills and I just feel bad in general. I have not had children, but want to proceed with a hysterectomy in order to feel some relief. I have given birth control and Lupron a chance but feel as though I am down to my last option. I suggest you try Lupron as iy may work for you, it just hasn't helped me :-( F 25 2 months
1/19/2010
 4  endometriosis,post-surgery Hot flashes, joint pain and stiffness (severe), weight gain, vaginal infections, fatigue, insomnia. Overall, I think the lack of pain and bleeding has been worth the side effects. I absolutely cannot seem to lose weight no matter how little I eat or how much I exercise, and it hurts. I guess this is a preview of my sixties? F 41 6 months
1/18/2010
 2  Fibroid Tumors Hypertension, chest pains, anxiety, loss of appetite, racy heartbeat, restlessness... My Dr. prescribed Lupron to shrink tumors & reduce bleeding before hysterectomy. It's been 4 weeks since the shot and the bleeding has reduced but not stopped like i was told it would. I feel horrible. My Blood Pressure has gone up & im now on bp medication, it doesn't seem to be helping with the racy heartbeat nor the chest pains. I'm also taking Lorazepan for anxiety, that seems to help with the racy heartbeat & chest pains, but problem is as soon as it wears off, i'm back at square one. Dr. says to her knowledge hypertension and chest pains are not side effects associated with Lupron...... Is it just me? F 47 4 weeks
1/15/2010
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 3  Endometriosis/Ovarian Cysts Weight gain, hair thinning, moodiness, occasional headaches After removing ovarian cysts, my doctor prescribed lupron injections for the next six months. I just had my fourth injection, and the side effects continue to cause me grief. I can tolerate the hot flashes and mood swings, but the weight gain and hair thinning are very discouraging. F 28 4 months
1/9/2010
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 4  Endometriosis Mood swings after the 1st and 2nd injections that have since resolved. Mild hot flashes, Mild hair thinning. Had one period after 1st injection and none since. I'm on injection 4 of 6. Many of these reviews almost made me refuse the Lupron, but I'm glad I didn't. Its not bad at all, I feel just like I did before taking it, no big deal. Also - As far as weight gain is concerned, I started a diet/exercise program when I started Lupron and went from 145 to 125 with no problem :) F 24 4 months
1/7/2010
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 4  prostate cancer muscle atrophy, total loss of libido, lethargy, hot flashes, etc, etc the muscle atrophy has been the biggest problem for me. even after stopping the treatments, i can't build any muscle mass and my libido is still shot. I took five 3-month shots and my PSA went from very high to very low. I had my last shot nearly 9 months ago and while my PSA is still low, I still feel like a middle aged woman (attempt at humor). I walk 3 miles a day to help keep my blood sugar under control and it is still a chore to complete. I am going to ask my oncologist if I can get a testosterone shot or something to help with the muscle atrophy. M 61 15 months
1/7/2010
 3  endomitriosis hot flashes,joint pain,fatigue i developed black spots under my eyes.was wondering if this happened to anyone else????please email me. F 36 1 years
1/6/2010
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 5  Large Uterine Fibroids I did not have any side effects from Lupron. I had 9 Uterine Fibroids and was told abdominal surgery was my only option. I had read about the benefits of Lupron shrinking your uterus and fibroids prior to surgery as well as all the horror stories. I still discussed it with my doctor (specialist) as an option to have laproscopic surgery instead of abdominal if Lupron could help shrink them before hand. He was not very optomistic but said I could try since I was so fearful of open surgery. I had 1 shot per month for 3 months and it worked, I had a laproscopic hysterectomy 3 weeks ago and I feel great. Everyone reacts different to medication I had no side effects but was prepared for the worst. F 38 90 days
1/5/2010
 1  breast cancer prevention heart palpitations, anxiety, blurred vision, extreme depression, sucidal thoughts. I would never give this drug to anyone. I thought the side effects were horrible and that is after already going through chemotherapy which i think was easier on me than taking this drug. M 38 7 months
1/4/2010
 2  severe endometriosis I received my first shot of the supposed two in October. I didn't experience any of the normal side effects only that I had a period for over a month and it was far from spotting. I received an additional dose just two weeks ago as my estrogen had not dropped. I am now bleeding heavy again, suffering from headaches, insomnia, bad mood swings, depression and the extreme urge to cry alot, general joint pain and stiffness in my neck. I'm scheduled for another endometrial biopsy in a couple weeks to check my levels and schedule a third shots. I'm scheduled for surgery following the now third was supposed to be second shot. This is the second time I've taken Lupron the first time it went pretty normal my levels went down and they had me on a replacment hormone which made the side effects less dramatic. This time around has been horrible. Wondering if the diet I'm on is effecting me consist of alot of vitamins and natural herbs???? F 36 2 months
12/29/2009
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