LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  shrink a fibroid mild hot flashes now and then I would just like to say that before I started getting these injections, I went on this website and others to get info on side effects and because of that was terrified to try this. I have had little or no symptoms and am quite happy with my results, I had a miscarriage in January that may or may not have been caused by my fibroid. I did not want to take any chances, scared and very unsure, I went ahead with the injections. I had a 3 month course therapy and my fibroid shrunk in half . I am looking very forward to trying to get pregnant again without the fibroid being such a factor. Before you try this drug, remember everyone is different therefore everyone will have a different side effects. You will find that most people with something negative to say are the ones who will write about it. I am happy to say that I have had a positive result . F 38 3 months
4/21/2006
 1  adenomyosis/fibroids headaches, hot flashes, no energy, depression,pain in ovaries, dark eyes, aches and pains etc. why????????????? F 43 4 days
4/11/2006
 1  Fibroids SEVERE...Hot flashes, Weight Gain (30lbs in 2 months - Can't work out to lose the weight because I ache so bad), Memory Loss, Night Sweats, Joint Pain.....ALL SEVERE!!!!!!!!! Was told by my doctor to take to shrink fibroid. Got a prescription for 2 3-month shots. Took Lupron for 3 months before about 2 years ago. Thought it was a wonder drug (LOVED NOT HAVING ANY PERIODS). But take it for more than 3 months....that's when the "fun" begins. The first 3 months are fine (only hot flashes) but OH BOY!!!...when going into the 2nd round, THAT'S WHEN THE REAL SYMPTOMS HIT!!! The hot flashes and night sweats are soooooooo bad!!! I haven't slept all night in 3 months. My joints ache SO BAD!!! I will forget things that I said only seconds before. I'm can/will get overly emotional at any time. If it weren't for my Paxil and an understanding boss, I would have NO JOB!!!! I've gained so much weight. How can I work out when I ache like this!?!? I WILL NEVER TAKE THIS MEDICINE AGAIN!!! I'VE CHANGED DOCTORS! HAVING SURGERY TO REMOVE TO REMOVE THE FIBROID AND LOOKING FORWARD TO IT!...Oh, I forgot to mention...IT DIDN'T EVEN SHRINK THE FIBROID!!!! A complete was F 35 6 months
3/30/2006
 2  Endometriosis Hot flashes, night sweats, fatigue, mood swings, weight gain. I took Lupron after having a laproscopy, and it was not a good experience. I was 19 at the time, and I felt like I was 50. I was tired and moody all the time, I had horrible hot flashes and night sweats, and I was in college! At the time, my doctor told me it was the only thing to do after surgery. Now I have decided not to have surgery again and I am taking Femara and a low dose BCP and I feel so much better than when I was on Lupron. F 24 3 months
3/24/2006
 4  Endometriosis I have had some mild hot flashes, mostly at night and some forgetfulness. I think I have been a little more irritable since I've been on it too. I was really afraid to get the shot and researched a lot about it before finally deciding to go for it. I'm glad I did b/c I haven't had any really bad side effects yet. Hot flashes and memory loss are worth the pain being gone. I'm getting ready to get my second shot in a couple days. F 25 1 months
3/23/2006
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 3  Endometriosis Adenomysosis Migraines (almost daily), hot flashes, memory/concentration problems, fatigue, blues, irritability, mood swings...UGH I give it a 3 for now, my endo is feeling better, but I hope it is worth it and lasts! The mirgraines are the worst for me. F 34 30 days
3/8/2006
 2  possible endometriosis, cramps constipation, hot flashes, joint pain, severe headache, memory loss, severe depression, bleeding I started taking this medication a year after my 3rd child was born. My 2d child passed away, and i have problems carrying children past the 7th month. all my kids were early. So, after the 3rd kid, I started having painful intercourse, bad periods and headaches. I asked my doctor what to do, or could she give me a tubal or hysterectomy. she told me that she would not consider any of those until i tried this "wonder drug". No success. this stuff stinks. i have had no relief from anything and i have started to bleed for no reason. don't let your doc pressure you into this. you know your body better than anyone else. F 32 3 months
2/23/2006
 5  Endometriosis Hot Flashes, Forgetfulness I am extremely happy with this medication. I have had six surgeries for endometriosis and complications from adhesions, including a hysterectomy. I still have one ovary, so estrogen still stimulates the hidden endometriosis. The pain was getting steadily worse, so my doctor suggested Lupron before we tried a seventh surgery. I was skeptical, but gave it a try. After two bad weeks during the initial surge of hormones, the pain slowly disappeared. I'm in my third month and my doctor wants me to stay on it indefinitely. Before, pain was a significant part of my life. I couldn't exercise regularly and felt generally unwell. Once the surge was done and the pain left me, I have been able to exercise everyday. I feel great! I'll take the hot flashes over pain any day of the week. This give me hope that I will finally be done with this disease when I reach menopause. In the meantime, this drug will help me to keep the endo under control. F 41 75 days
2/2/2006
 4  Fibroid Slight flushing, a few actual hot flashes, vafinal dryness, prickly heat in the first week of each dose, headache on first day of each dose. This medication healped me a great deal, after discussing it with my doctor we settled on the lower 3.75 dose just to minimize the occurence of side effects. I'd been miserable for over a year prior to getting lupron then getting my surgery. F 27 60 days
1/23/2006
 3  fibroids Took lupron pre-operatively to shrink the fibroids 3 mos before. side effects were immediate (within 1 day or 2 of getting the first shot). I had abnormal cramping, vicious stabbing pains (worse than the pain of just having the fibroids themselves). then the lovely hot flashes started. Night sweats and waking up in pools of sweat. And then the mood swings - my mood was up and down like a toilet seat. Not prone to crying or getting overly emotional, but this stuff made me a mess. A weird side effect also, along with the cramping, I all of a sudden started getting weird vaginal discharge (never ever had this before and it freaked me out). It wasn't bloody or anything, but *watery* and it would come out in gushes, to the point where it would soak my underwear in a couple of seconds if I wasn't wearing a pantiliner. To this day (and I've been off of Lupron for 7 months now) - I'm still getting the gushers of watery discharge that just come whenever it feels like. My surgeon says it coul F 36 3 months
1/4/2006
 1  endometriosis severe hot flashes; migraine headaches; inability to function (permanent disability) due to memory and cognitive impairment, anxiety, mood swings, depression; permanent significant hair loss; some permanent change in height and stature due to osteoporosis; permanent loss of sex drive This is a dangerous drug. I understand that some people are helped by it but the risks are too too high. I would NEVER recommend this drug to anyone. I can't believe it is on the market without serious disclaimers. I was not told the risks. I would have a complete hysterectomy (and I am a woman of childbearing age who would like to have a child) before taking this drug. F 40 6 months
12/10/2005
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 4  Endometrios Mood swings,Very rapid weight gain the first week,nausea,dizzy,short term memory loss,lost interest in intimacy,depression,hot flashes - ohhhh the hot flashes are BAD!aches and pains in my joints and bones,headaches,heart flutters. I have taken Lupron for 6 mos. for endometrios.I have had all the symptoms others have had. Even though the road is a little rocky - the pain I felt for many years (having no idea I had endometrios) has left.. I enjoy sex - there are feelings there that I did not know existed (due to the fact my endo had spread so bad I thought it was a regular thing) I highly recommend you to go with the treatment if you need it. Iam not going to lie to you..it is irritaing and the night sweats and mood swings get bad... but it will go by before you know it and the relief you get from it after all is done - its wonderful - to feel such relief from the pain. Dont suffer because your scared... we all are... it will be ok.So far no one has died from it.. so it is safe. Do all the research you can and speak with many doctors before making a decision. Good Luck in you r journey to feeling better! F 27 6 months
11/27/2005
 5  adenomyosis mild hot flashes and muscle weakness, headaches (1st mo), memory loss (1st mo), leg cramps (1st mo) Adding Calcium & Omega 3 helped! Yes, there were some side effects, but for me the hot flashes were just a novelty-strange feeling more than offensive. Maybe it was just a good match for my body, or from following the recommendations of the support RN via the Lupron depot website?? She told me what to avoid - excess sugar (Splenda was fine), spicy foods, very hot environments, hot drinks, caffeine...soy products- as they counter the therapeutic effect of Lupron. I've had ZERO pain, which was revolutionary!, no periods, no decrease in sex drive, some emotional moments, but overall more "balanced" and peaceful feeling than I've been in 15 years!! At 3 months, by US the adenomyosis had shrunk drastically!! My last 30 day-injection was Sept 22, and I'm still feeling good, just waiting for my period to return, then hoping for another pregnancy. I would take it again in a heartbeat, to feel the way I do now. If you're miserable, you owe yourself a chance trying it--take the monthly version if you're unsure, re F 39 4 months
11/19/2005
 5  Endo, Fibroids, Enlarged Uterus It honestly feels as if I'm not on anything at all, and I'm in my third month of treatment. I'm normally 'cold-blooded', so if I have had hot flashes, they have been minimal and barely noticeable. No weight gain or loss, no lowered sex-drive, no mood swings, headaches, NOTHING really to speak of. Only thing is I had a 5 week period two weeks after my first injection, but after about 11 or 12 days it was pretty light. Nothing at ALL like my normal, nasty periods (still needed a pad, though). Was having a lot of pain up till two weeks after my second injection. Lately I've been feeling GREAT! It reminds me of life before my estrogen levels were so high. I've had chronic pelvic pain since I was 11 years old (I'm almost 37 now), and I was even willing to deal with hair loss if it meant I could feel better (thank God, though, no real side effects at all for me!). I just thank God for some relief! For me, it's working with NO side effects. I know everyone's body is different, but for those suffering with severe pain as I was, I highly recommend it. F 36 2 months
11/5/2005
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 1  Endometriosis UGH! I CANT BELIEVE IT'S LEGAL! On Lupron, I experienced no benefit other than cycle interruption. The lupron did not 'cure me' of or even 'shrink' endometriosis. It had progressed alarmingly in fact during the 7 months that I was on it. I had severe menopausal like symptoms, skin & hair changes, continued pain, memory problems, immune disfunction,exhaustion, weakness, frequent bladder & yeast infections, severe depression and more. Some symptoms, like bone density reduction stuck with me. People who have questions about Lupron should definitely search google for all of the pro's and con's before agreeing to even try this drug. Search for Dr.Friedmans' admission of falsifying data in relation to the study that the FDA Based their approval of this drug (in the use of treatment of endometriosis) on. I wish that I had done so in the first place! You will be happy that you did! F 34 7 months
10/2/2005
 4  Endometriosis Severe hot flashes, vaginal dryness, nightsweats, insomnia, joint soreness This is my fourth time taking Lupron. It has helped tremendoulsy with the pain. However, I cannot stay on it for much longer due to the risk for osteoporosis. In a month, I have to decide whether I want to undergo my seventh pelvic surgery or if I want to have a hysterectomy. My biggest problem right now is that I have started my period (eight months into treatment). I have never had break-through bleeding on previous cycles of treatment. I don't know what's wrong!! F 26 8 months
9/30/2005
 1  endometriosis unrelenting muscle pain(for over 1 year after stopped taking it)hot flashes, night sweats, severe mood swings, sugar cravings, weight gain that won't go away(15 pounds from 2 only monthly injections)fatigue, continuous headache for 3 months, heart palpatations, TOTAL loss of libido while on it, bleeding, pelvic pain, cystic acne, weakness, insomnia, etc! Taking Lupron was one of the worst things I have done to my poor body. I didn't want to take it and caved to the pressure from my Doctor. If you have a bad feeling about a medicine, do not let a doc pressure you into it! It is your body and you have to live with the side effects, they get to go home at the end of the day. I have fibro too and the doc didn't believe Lupron could make it flare, well it did! The muscle pain was so severe I was taking so many muscle relaxers and pain pills everyday just to get out of bed. I still had the endo pain. It didn't slow or stop the progression of my disease at all. It took me over a year to get back to normal. It was supposed to help and it only added to my misery. It's a terrible drug. I think the people who take it and have good results are in the minority. F 30 2 months
9/30/2005
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 1  To suppress estrogen after breast Debilitating muscle and joint pain that went on for months. I stopped taking it, but am completely run down and exhausted as a result - plus I gained a lot of weight as I felt terrible and had to stop exercising. I'm not sure I'll ever get my health back. F 49 3 months
9/8/2005
 5  Endometriosis Occassional hot flashes, nausea. My husband wants to send my doc flowers after I received one shot, due for the second next week. (Did the two/six months). I was miserable for about 10 years before getting the shot, but am glad I did. My entire mood changed, probably because I wasn't feeling so bad. My frequent migraines, cramps and mood swings disappeared. The only problem I've had so far is now at the end of the three-month period of the first shot, I feel like I can tell the shot is wearing off — I've been getting some cramping in my leg and utie area, but fortunately haven't seen any bleeding yet. I read a lot on this before doing it, and am glad I did. I only hope the second shot lasts longer as I do not want to have to undergo a hysterectomy. F 27 3 months
9/1/2005
 2  Fibroid Tumors Hot flashes, night sweats, dizziness, bone pain, bone loss, heart palpitations, blurry vision, lack of sleep, severe head-aches. If given the opportunity to take it again, I wouldn't. There has to be another alternative. F 39 6 months
8/31/2005

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