LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Fibroid None I took my first shot a week ago, I haven't had any side effects at all, will update in 4 weeks more. I'm taking the dosage to try to shrunk a large fibroid for surgery. F 29 7 days
11.25 X 3 1X M
7/18/2010
 1  Severe Endometriosis Depression, dryness, severe mood swings, acne, weight gain, insomnia, nervousness, anxiety, loss of sexual interest, dry mouth, hot flashes I had a laparoscopy last year, and they found that I'm covered in endo. I had to diagnose myself with endo, after YEARS of complaining to doctors. They didn't remove any of it, except what they thought was causing pain with intercourse, and recommended that I take Lupron for a year, and then have a full hysterectomy. The first month shot was crazy, I had a hard time performing at work (still do), but I agreed to two more 3 month shots after that. I was hoping to stop my period until we could decide to have kids or not. I am extremely active, and do crossfit workouts 4 times a week, so I shouldn't be looking like I'm pregnant. My stomach is getting bigger and bigger! I've never been overweight before in my life. I'm never going to take this shot again, I don't care how bad my periods are. Between the first one month shot and the second 3 month shot, my doctor's assistant didn't order the shots on time, and I had my period for 2 months straight! Also a huge piece of light pink flesh came out of me, the size of three fingers together. I called my doctor, and they just giggled, and suggested that, "all kinds of crazy things come out of vaginas". I've been to several doctors, and they all suggest this drug. I feel like the doctors just don't really care about endo, and this is a catch-all treatment. Why would you want to make your brain believe you are in menopause? There is something seriously wrong with this hard core solution. F 35 7 months
3month sho 1X O
7/15/2010
 1  endometriosis nausa,vomiting,diarrhea,chills,stomach cramps,anxiety, not hungry at all. I have been on this medication for 3 weeks now and it has been an horrible experience. I have been so sick.At this moment I'm making myself eat. I am supposed to get another shot in 3 months and I will not be getting it. F 32 3 weeks
11.25 1X O
7/14/2010
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 3  Fibroids Forgetfullness, loss of appetite, tired, daily spotting, sleeplessness, weight gain (10 lbs), emotional fits, a quick period every 3 weeks, mood swings I felt the need to comment on this drug. I took this for 3 months, and unfortunately did not have any shrinkage of my fibroids. I will be getting a myomectomy in a little bit. The most profound side effect was a very intense period about 2 weeks after I had my initial injection. I thought I was going to die... Otherwise, most of my physical symptoms weren't bad. My emotional state was not good, mood swings certainly present, and marked emotional times happened every few weeks. Also, I noticed my general heart rate/pulse went down. Just a strange drug. F 30 3 months
3 month 1X M
7/12/2010
 4  endometriosis nothing for now i had my first shot a week ago and i have been doing fine, side effect might be to small to notice. i ll keep you updated in 4 weeks. F 27 6 months
11mg 1X O
7/11/2010
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 5  Endometriosis I was very emotional and angry for the first 1-3 weeks. I was menstruating when I received my first shot and then had another, very persistent period with heavy flow about 1.5 weeks later that lasted for about 8-10 days. I have gained a few pounds, but I think that is a result of emotional eating the first month. I was terrified to take this drug after reading what other people said about their experiences with it. I actually delayed taking it for two months as I hashed it out with my OBGYN. In the end, I trusted her that the side effects are minimal and that the benefits are great. As my hormones fluctuated the first few weeks I did have an additional period and very emotional mood swings (but this was expected). By the end of the first month I can say that I feel great! I just received my second shot. I am pain free, period free and am so glad that I decided to go with Lupron. And no...I don't work for the drug company, I'm a teacher. Please contact me if you want to know more about my experience. F 32 2 months
3.75mg 1X M
6/23/2010
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 5  severe Endrometriosis 1st month: headaches, drowsiness, fatigue. 2nd-4th month: weight gain, moodiness, spotting, short period of heavy bleeding After having a Lap, still had Endro, so my Dr recommended Lupron. Like everyone else, I read the horror stories about the drug, and was terrified to take it. I knew it was my only chance at being able to have kids one day, so I agreed to take it for 6 months. I have had a 1 month injection and a 3 month injection (which made it nice that I didn't have to go every month for an injection) I've read alot that after a month, girls have had bad side effects and quit Lupron. Well, the 1st month is when your body is getting used to it, and it's probably the worst month. I haven't had any hot flashes or night sweats. The biggest side effect has been moodiness. After taking it, I got depressed and was very edgy. So my Dr put me on Wellbutron, an anti-depressant. I didn't like the thought of being on it, but it's made such a difference, and now I've never been happier! I had very severe cramping and pains for many years, and I've had absolutely NO pain since I've been on this drug, for the exception of one cramp about the 2nd month in. There was a month that I didn't have much sex drive, and dryness has been an issue. I've had light spotting, and my 3rd (and now my 4th) month into it, I had a week of heavy bleeding. I found out from my Dr that "breakthrough bleeding" can be a side effect from this drug. I did gain 20 pounds. I hate it, but most will go away once I'm off the drug. Not everyone has the same side effects, but overall, I'm extremely happy that I went through with F 23 4 months
1X AN
6/22/2010
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 1  Supposed Endometriosis Too many to describe I can write a book on the HORRIBLE things this did to my body and almost 5 years later, I'm still suffering! Any chemical that alters the function of your pituitary gland (the master gland that controls everything, can't be good!!! F 44 6 months
1X M
6/22/2010
 5  Endometriosis Hot flashes, night sweats!!!! Lupron saved my life! I was diagnosed last Sept'09 with Endometriosis. My cyst was 14cm in diameter! After surgery we tried to get pregnant w/out success. My periods were awful, I was in so much pain that I was doubled over. The pain was so bad I cried myself to sleep. After months of trying and having severe pain during my period I went back to my doctor to find out the endometriosis was back, this time it was 11cm in diameter. My doctor suggested Lupron, I had no idea what the drug was all about or how it would affect me. I was willing to try anything at this point. I've been on Lupron for 3 months now and have experienced a huge difference. I feel like I have my life back. The pain is GONE. I have hot flashes all the time, which is annoying but it's worth it. The night sweats are constant, I've also noticed a big difference in my sleep patterns. I would normally wake up once or twice before the Lupron. Now, I'm waiting up 5-6 times b/c I'm hot, thirsty or have to use the bathroom. I'm having surgery next month to removed the endometrioma. After surgery we're going right into IVF. I would strongly recommend Lupron to anyone with Endometriosis. It's a life saver!!! Good luck to all! F 34 3 months
3.75mg 1X M
6/17/2010
 3  Endo/infertility hot flashes, increased appetite, mood swings I cannot say if it worked or not...I will have my last injection July 1 and then can start trying to get pregnant again. If I get pregnant, obviously it worked, if not, then I am not sure. F 25 3 months
1X M
6/15/2010
 4  Endometriosis depression, night sweats, fatigue, irritability, anger Don't believe the reports! Yes, the drug will put you into "menopause," with all that comes along with that, but that's how the drug is designed! And, above all, it actually WORKS!! I had severe endo pain every month with inexplicable pain during the month also. I read the nay-sayers and was terrified to take the injection. I am so glad I did. If my doctor would give it to me, I would stay on it forever. You will definitely want to talk with your doctor if you start to feel really moody or depressed, because you might need another drug like me (Zoloft). However, I'd rather be on Zoloft and NOT IN PAIN than just IN PAIN! F 27 6 months
3.75 1X M
6/13/2010
 1  to try and shrink fibroids my side effects were dizziness, hot flashes, violent mood swings, joint pain my doctor told me i needed it because i had fibroids which was causing anemia. she never told me about side effects, only that it would stop my period. when i took 1st shot i bled for 1 month and a half. i told her i didn't want another one and she said i had to or she wouldn't do surgery. my surgery is scheduled for this tuesday and after taking this drug i still have to be cut, because it didn't shrink fibroids F 34 3 months
3.75 1X M
6/12/2010
 5  Endometriosis hot flashes, dizziness, weight gain, mood swings, anxiety I just took the final injection to treat my endometriosis. The injections often made me extremely hot and moody. The pain, however, is gone. I am very happy with the outcome of the treatment, but I HATE the side effects that come with this drug. F 17 3 months
1X M
6/6/2010
 5  Endometriosis increased appetite, minimal weight gain (2 lbs), extremely infrequent hot flashes I read other peoples comments about this drug before beginning treatment, and it made me very skeptical. I'm very happy that I went through with receiving the injections, however. I have gone four months without having any discomfort related to my endometriosis. My symptoms are also VERY minimal. The first few weeks were hard, just with adjusting to the new med. I had frequent headaches and an increase in stomach cramping. But after that, I've never felt better. I have a hot flash every once in a while. In the last four months I've probably only had a handful of them. My appetite had increased, and I've gained a few pounds, but I've been able to control it with regular exercise, so it isn't concerning to me. Overall I've responded extremely well, and I'm so glad that I took the chance on this medication. I know there are so many negative comments about Lupron, but every individual person is going to respond differently. My advice is to at least try it. I decided to give it a try even when I was worried about all the potential complications, and I'm so happy that I did. F 23 4 months
3.75 mg 1X M
5/30/2010
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 3  fibroids painful joint pain, vaginal discharge continuously (faint bleeding to watery), 2nd month severe cramping My hemoglobin was so low I had to be hospitalized and transfusions. The lupron by the second month had slowed my periods down quite a bit. I think my fibroids have shrunk but there are side effects. My joints ache all day long, especially my feet, ankles, hands and fingers. I wake up almost crying from the joint pain. I have not had hot flashes yet. I have mood swings but cant say if its from the drug. M 46 2 months
monthly 1X M
5/25/2010
 4  Endometriosis I have had terrible hot flashes, and more recently my endo symptoms have come back. Well without boing you with TMI. I have had 4 laps (2005,2006, 2007,2008) Following my last one I was put on Lupron I have taken it continuously (except for 2 months) since then. I get bone density scans every 6 months. It has been a life saver. I am hoping when I have my next lap the docs will say I have the green light to have babies...Don't rule it out. Taking Lupron gave me an extra year of no surgery...The side effects are mild compared to the pain!! F 22 2.5 years
3.25mg 1X M
5/22/2010
 1  shrink fibroids for a hysterectomy The sample shot made me bleed continuously for 4 weeks until I got the 3month depot. That shot stopped my flow but made my emotions go crazy. By the 3rd week I was angry all the time, and was suffering from violent hot flashes that were much worse than the sample stuff. Depression set in by the 2nd month followed by a tapering off of the emotional stuff but the hair loss in the third month? OMG! Handfuls of hair after each washing. Went from wearing my hair in 4 individual ponytails to just one because there wasn't enough hair for four anymore. I'm not bald but my hair is dramatically thinner. Worst of all, the main fibroid they were trying to shrink didn't reduce at all after 4 months on it. I refused to take the second shot the GYN wanted to give me. I'll take an abdominal cut rather than go through that for 3 more months hoping for laproscopic surgery. One more thing: High Blood Pressure! I've never had a high reading in my life. After I asked the gyn about the side eff So the GYN put me on the pill to bring my estrogen levels up. I asked her how long til my own kick back in, she said 2-3 months. Wow. The withdrawal from this stuff takes a long time huh? F 45 4 months
3mo Depot+ 1X O
5/20/2010
 1  Endometriosis Severe anxiety attacks, mood swings. I was supposed to take 6 injections over 6 months. Thank goodness my symptoms appeared within the first two weeks because I cancelled my prescription. Although the pain went away for a couple of weeks, it came back with a vengeance! I was having severe anxiety attacks and mood swings. 2 months after getting off of the Lupron, I had a miscarriage and will be having my uterus and ovaries removed. I wish I'd had this done from the start... AVOID LURPON! F 37 1 months
1X M
5/19/2010
 4  Severe Endometriosis minimal hot flashes, night sweats, loss of sex drive I had my second of three shots on May 12, 2010 and so far I have been pain free. I would take the side effects that I am having over the pain I experienced for years. I have not gained a pound. I try to eat healthy, and exercise at least 3-4 times per week i.e. brisk walking for at least half hour using Leslie Sansone's walk-at-home program. I must say that I am happy with Lupron and what it has done for me. I guess everyone's body is different but some side effects can be controlled e.g. weight gain. I must mention that I have somewhat lost my sex drive but my husband understands and is very supportive. The priority right now is knowing that I am feeling much better. This too shall pass. F 37 2 months
1X M
5/18/2010
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 4  endo F 47
unknown 1X day
5/16/2010
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