LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  one huge fibroid I get brief waves of nausea for the first 2 weeks after I get a shot. I get some hot flashes, but they last just a few seconds. I have night sweats occasionally, but I had those before. I feel as though I've been on a nine-month vacation. I dread going back to normal, as I had my very last shot yesterday. My only disappointment is that I cannot take it until menopause is officially over for me. I used to have such heavy periods that they were affecting my CAREER by preventing me from volunteering for activities, because I didn't know what my menstrual situation was going to be like. I had unpredictable, heavy periods where I was soaking a tampon AND A PAD every hour. Plus, my iron was so low that I've had to take supplements for years. F 46 9 months
10/15/2008
 3  Pre-hysterectomy treatment Am about to take my 3rd (3 month) dose of Lupron next week. Feel like I am 90 years old. Joint pain, have now developed "tennis elbow," have several tears in my knees, daily headaches, feeling bloated/full all the time or starving. I have experienced extreme fatigue yet sleeplessness also. Was supposed to stop my periods completely to build up my hemoglobin levels and iron levels. I have had spotting continually since day one of treatment. Dr. says this is fine and my levels are increasing for December. Granted I'm not getting the horrific, painful, can't leave the house menses I had, but I still need to have something for the never ending spotting. All in all I don't like to takes meds I don't have to but the promise of being period free and bringing up my levels was more appealing. I truly hope when I go off this medication that I return to normal health! F 40 55 days
10/12/2008
 2  endometriosis only after days of taking the 3 month injection of lupron i started experiencing the heart palpations along with itching and difficulty breathing which caused me to develop asthma and have other medical problems i was placed on prednisone for the hives and i had to continue taking that medication for over year i was also experiencing fatigue i would be able to go to work and function but when i got home all i wanted to do is sleep F 31 7 days
10/12/2008
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 4  Shrink large fibroids - Pre Op Headaches, dizziness, acne, fatigue, mild depression, short term memory loss, vaginal dryness I am on a 4 month therapy to help shrink fibroids, before I undergo a partial hysterectomy in December. I don't have the heavy bleeding/pain that I experienced previously and the side effects seem worth it, as they are not too severe for me. It's better than not being able to leave the house because of heavy bleeding accidents. F 47 4 months
10/7/2008
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 3  Chronic pelvic pain and endo Hot flashes, headaches, severe memory loss, concentration/focus problems. HUGE DIFFERENCE when I take B vitamins. I found this out on accident when I drank energy drinks and then stopped, the ones I was drinking were loaded with B vitamins. I have been on it for about 3 months and have another shot to go that'll last 3 more months. Everyone's body is going to respond a little different, for me the hot flashes and headaches were pretty quick after the shot, then the memory problems rolled in after a few weeks or so. Overall I can function as normal, mainly by keeping B Vitamins in me regularly. A couple tips I found with night hot flashes, don't sleep on your stomach! Also, I found when I get nervous, drink alcohol, or am in general hot- my flashes were way worse. F 31 3 months
10/7/2008
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 2  endometreosis Hot flashes, insomnia, mood swings, fatigue, night sweats, vaginal dryness, loss of sex drive, depression I decided to take Lupron because of the advice my doctor gave me. I had a laparoscopy in March and the endometreosis was removed but the pain was not relieved. The Lupron did help my back pain, but the additional side effects were not worth it. I feel like I have a totally different personality now and am constantly tired. I can not sleep more than 2-3 hours a night when I don't take a sleeping pill. I only received one injection and declined receiving a second dose. My back pain is slowly coming back, but unfortuanately none of the side effects from Luron are going away. My body still hasn't resumed a normal menstrual cycle. DO NOT TAKE THIS DRUG UNLESS YOU HAVE NO OTHER OPTIONS! F 21 4 months
10/7/2008
 5  Endometriosis Weight gain, headaches After having bad experiences on several birth controls to curtail my endomeriosis (to no avail) my doctor and I decided to try Lupron. I am nearng my third 3 month injection and the only side effects I have had are headaches and weight gain. I gained about 20 pounds but I seemed to have plateaued now which is fine by me, as it pales in comparison to my cycles and the effects from them, which included migraine, nausea, vomiting, and extreme malaise and fatigue. My endomeriosis also has gone down considerably so I no longer have to worry about another surgery. Lupron gave me back my life. F 23 8 months
10/6/2008
 4  Infertility Hot flashes, interrupted sleep, weight gain, dizziness, headache. I am also diabetic and it seems to lower my blood sugars. This drug worked for me, we have a healthy baby boy. F 35 14 days
10/4/2008
 3  uterine fibroids none thus far I have a question. How quickly does this drug take effect? I just got my first dose on Sept. 19th. I was supposed to start my next period Sept. 22nd. It can't work that fast, can it? I mean, there are other reasons why my period might be wonky, it often is, but this is weird. I've had more energy lately and my stomach looks like my stomach for the first time in I don't know how many years. The general fatigue, pain, and malaise that came from my fibroids seems to have evaporated. I don't trust anything that works this fast but I have to say that I feel better than I've felt in the past year. F 37 7 days
9/25/2008
 1  Prostate Cancer Dangerously high blood pressure and excrutiating joint pain in my left foot. I was 79 when diagnosed with prostate cancer and was treated at a world renown clinic. I was given a 1-month injection followed by a 4-month injection. About two weeks after the 4-month injection all hell broke loose. I had frequent blood pressure readings in the 200+/100+ range, sending me to the OR three times in three weeks. My BP med was doubled and another added before my BP was brought down to 140-150 over 80's range. The pain in my left toe joints was so severe I had pretty much decided that if the pain didn't diminish as the drug wore off I would need to have my toes amputated.I was never warned of these side effects.In fact, I could never convince the oncologist at the clinic that these problems were Lupron induced. He kept repeating that in 80 patients none had complained of these problems. Thank God that the pain and BP problems abated as the drug wore off, M 80 5 months
9/25/2008
 2  Endo/Extreme Bleeding hot flashes, night sweats, weight gain I cant stand this I thought everything was great and it was until my second shot now I have put on about 5 lbs and cant slee due to night sweats I am sweating like a pig I feel grose alot of the time. I am supposed to be on this for 6 months but I think this is it. I ant more children but not if I have to go through this F 21 2 months
9/24/2008
 5  Endo Headaches for the first 4-5 days after injection, mild and very infrequent hot flashes / night sweats. Nothing more :) After reading many of the comments on this site, I was really concerned about the side effects of Lupron. However my experience has been really positive! I had a low grade but persistent headache for the first 4-5 days after the injection and I have experienced a handful of very mild hot flashes. No weight gain, no acne, no vaginal dryness, no decreased sex dive, no beard :), no other side effects!! I'm a full month into the treatment and looking forward to the endo pain relief I anticipate to experience starting next month. I am taking norethindrone (add-back therapy) but didn't start that until 2 weeks into treatment. My side effects have been so mild that I can't even notice the difference norethindrone makes! Can't wait for pain relief - give this drug a shot! F 31 30 days
9/20/2008
 1  Endo Severe Dizziness, joint pain in my feet and legs, forgetfulness; blood work high for liver and kidney function; headaches; fatigue; breast tenderness; slight swelling in belly area Would never recommend. I too was great on the drug for the first month injection and then a three month injection but when I received the 2nd three month injection and started to experience severe dizziness ever since and that was in JUne. Very frustrating because I am dizzy every day and it makes me very tired. My feet also hurt when I get out of bed in the morning. I cannot wait to have my period since my hope is that the symptoms will decrease. 6 months
9/19/2008
 5  endometriosis hot flashes, mild depression, mood swings, dry mouth and thristy. I was diagnosed with endomitriosis years ago. Completely frightened by the throught of Lupron I did nothing for a few years. About 5 months ago my pain from endo was too much to bare. I talked to my Doctor extensively about Lupron and decided to give it a shot. We had decided to do a 3 month trial, one month at a time to monitor side effects. I recently had my fourth injection (over a 4 month period). To me the side effects are worth being pain free. It has helped to have an understanding, support system and Doctor who took as much time as I needed answering my questions. My doctor told me that the younger you are the less side effects you tend to feel (relates to how much estrogen your body is producing). F 28 4 months
9/17/2008
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 2  pelvic congestion syndrome I am experiencing major heat flashes, extreme levels of fatigue, my neck, lower back and leg muscles are very sore all day (feels like I am training for the olympics..and I'm not excersing at all). At times I feel like my heart is going to pound through my chest from being so anxious. And somebody please staple my mouth shut, cause alls I want to do is eat!!!! I was diagnosed with pelvic congestion syndrome, which is vericose veins on the ovaries. I am scheduled to get a shot of Lupron every month for a year. I had only had one shot thus far and so far have been experiencing some pretty intense side effects from them. Will the side effects subside with each shot or will they get worse??? Not really sure what to do. F 32
9/11/2008
 1  uterine fibroids - post myomectomy I posted here before surgery. My last injection was 2 april with effect for 3 months until July 7 day of my minilaparotomy myomectomy. Doctor removed 8 fibroids and left my uterus fine. Initially biggest fibroid was over 5cm, lupron reduced it to 3.5cm & others shrunk too. I haven't had a period since Dec. 2007. I still have the menaupause, get a little hot, still overly sensitive and pretty depressed even with anti-depressants. A little joint pain (knees). Column pain is gone. The effects are still not completely out of my system. Because I have felt so extremely depressed, suicidal I would not recommend this. I regret having taking it. If I would have known I wouldn't have never taken it. I have always been a super healthy person, eating good food, no junk food ever, don't smoke, don't drink, a lot of exercise, running, weights, swimming but this has a way to break you completely. If you have a history of depression as I had PLEASE DO NOT TAKE LUPRON, you may risk to commit suicide or live in hell. Doctor told me in 2 months effects are gone but some still there. What to do to get back to normal? How long it took women a little younger than myself to get the period back? F 47 7 months
9/11/2008
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 5  catamenial pneumothorax initially some hot flashes, vaginal dryness. With add-back therapy they have gone away. My lung used to collapse everytime I got my period. I was told this was caused by endometrial cells migrating to my lung. I have been on Lupron for almost 1 year. I get injections every 3 mo. This has totally solved the problem. No more lung collapses! I also take a small dose of add-back therapy. I am very happy with the results. Side effects are so minimal, it's worth it. F 39 1 years
9/10/2008
 5  endometriosis hot flashes-now having some nausea but unsure if related to this my incisional pain(my endometriosis set itself up in my c section incision)felt like a brand new incision each month and had gotten to the point of lasting 9 days or so and also started causing severe back pain-this injection has given me now 4 pain free months and i am ecstatic-i am preparing for my second injection next week... F 37 120 days
9/9/2008
 1  Endometrosis Hot Flashes, Night Sweats, Insomnia, Mood Swings, Joint Pain, Bone Pain, Unable to concentrate, Depression, Dry Skin. I was put on Lupron for 6 months after being diagnosed with severe Endometrosis. I was 34 at the time. My doctor didn't want to a hysterectomy at such a young age. It was the most horrific 6 months of my life. The side effects were life altering. Not only on me but on my family. I had insomnia to the point that I had to take sleeping pills and that didn't help. I suffered through Hot Flashes where I was constantly in shorts and my family was wrapped in blankets. I had severe night sweats where I literally had to get up and change my clothes and bedding. I forgot everything and anything. I suffered from bone pain that was so excruiating that I was taken to the Emergency Room and it took hours to figure out that it was a side effect. Not only did the Lupron not work. I couldn't work. I could barely function. In the end, I ended up having a total hysterectomy 11 months later. The Endo spread everywhere. I still suffer from depression, my relationship ended and I will never be the sam F 40 6 months
9/8/2008
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 4  Endometriosis Mild headaches, occassional night sweats, acne. I too was scared to begin taking lupron because of this website, but figured it was worth trying to get rid of the pain every month. I mentioned the severe side-effects some of you were getting to my nurse, and she said there are two different Luprons (?) and that my doctor will not prescribe the older one anymore because of such side effects. I have only experienced occassional headaches, and night sweats (very infrequent), and the acne is not pleasant, but worth it. I am on my last shot (6 months), so I cannot yet say if it will actually help my pain until I get my period again. I would do it again in the future if I have to! F 25 6 months
9/5/2008

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