LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  endomitriosis/fibroids complete lack of control of my body 4 days after 1st shot. no focus,unable to sleep, pain everywhere,moody,hot flashes, night sweats,paranoid,achy, tired, initially no desirre for sex, came back, no problem. the strongest of the side effects lasted for two weeks, had mild bleeding for 2 weeks, 2 weeks after the first shot. Had a myomectomy in july 2008/ fibroids came back along with endo/ had three good weeks out of the 12. scheduled for a hysterectomy on March 11. Supposed to take another shot/ will not. Can anyone tell me how long after you quit the shot did you start bleeding again??? F 45 60 days
2/5/2009
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 5  severe endometriosis None, except being free from pain Lupron has been a blessing to me! After reading this message board, I almost didn't get my injection, but I'm glad I did. It's been almost 6 weeks and for the first time in years, I've been pain free and able to actually live life, instead of planning my life around my endo pain. My experience has been GREAT and I want to make sure that GOOD comments are posted instead of all the other ones -- I've had no side effects at all and I've also been taking Prempro to lessen any side effects, should they appear but nothing! Lupron has been a lifesaver!!! F 44 6 weeks
2/4/2009
 3  Endomitriosis. hot flashes, massive mood swings, backaches, pain at the injection site. other side effects have occured. Okay so everyone on here is about the age of 20-40, and they have a problem with the injection, try being a junior in high school, at 17, and being slammed into menopause, as a last resort to TRY to make it possible for me to have kids. Which I may not be able to. I've had 3 shots so far, and yes the pain has gone down, but im not a very easy person to be around with the massive mood swings, and try getting through a day, in a class room where you have hot flashes, and can't wear a tank top to school. :/ im pretty miserable all the time, but this is what we have to do. in April of 2008 i had surgery and the doctor removed a cyst that was aprox 2 times the size of my uterus. She also burned away some endomitriosis, but she couldn't get all of it. By November the cyst was back(it is small but back again.) and i've had ultrasounds to track its size, it hasn't gotten much bigger, but im still aggervated that i have to go through all of this. :/ F 17 3 months
2/4/2009
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 2  possible endometriosis headaches, feeling crazy, crying spells, anger, not make that rage, growing sideburns, sensitive vagina (skin tears easily), fatigue. I thought it was a bad idea to go through menopause at age 28 but after taking birth control pills everyday for months and then getting my period for 2 months straight, i decided to try it. i took my 1st 3 month injection at the beginning on december and am not sure if i should take the next one in march. i had sex for the 1st time in over a month, not because i had to desire to, but because i felt so bad for my boyfriend and it burned the whole time. i am tired constantly and hate everyone. i need energy to smile. i noticed my nose is getting wider too. did that happen to anyone else or am i crazy? i'm growing sideburns too which are freaking me out, it better not become a beard. the endo specialist in my area doesn't recommend surgery because it's not a guarentee that it will not come back again. he says stay on lupron for 6 months and get pregnant as soon as possible. not really ready for that. oh, also having hot flashes, but moreso during the day. insomnia big time. and anxiety at F 28 2 months
2/2/2009
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 4  Endometriosis VERY mild hot flash. Were actually welcome as it is winter in Maine!! Occasional spotting. This has worked nicely so far for me. F 27 2 months
2/1/2009
 1  polycystic ovary Extreme fatigue, horrible backache, dry skin, headache, burning sensation in legs when I lie down, depression Taking it to shut ovary down and put me into menopause. It has been one and a half weeks since I got my first shot and I have never felt worse in my life. I feel like I have the flu. F 36 1.5 weeks
2/1/2009
 3  Uterine Fibroids Mild headaches, some mild hot flashes during the night, sleeplessness, irritability and depression I had my initial injection on Jan 9th in preparation for a hysterectomy. I have been on a mild menstrual cycle for 19 days and will have my next injection on Feb 5th. I will await the final result. F 42 25 days
1/30/2009
 4  endometriosis headaches, pain at the injection site, hot flashes, mood swings, increased appetite, increased sweating, short term memory problems after injections i tend to have pain at the injection site for about a week. it just feels like a bruise. I also tend to have headaches for the first couple weeks after an injection, but they're not too bad. For about a month after an injection i ahve problems retaining short term memory and this tends to make it difficult to focus. I've gained a lot of weight and have the typical menopause symptoms, but it has definitely helped my pain associated with endometriosis. Ive especially noticed a difference in regards to pain during intercourse. F 21 4 months
1/29/2009
 1  endo hot flashes/ mood swings/ body pains/ night sweats/ real bad leg pains at night/ I have been on lupron for 6 months. i have not seen any change in pain. it is getting worse. i have already had one surgery for this and the dr is saying there is a good chance i will have to have another one. i am very scared that this is going to have a effect on me having kids F 20 6 months
1/28/2009
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 3  Endometriosis hot flashes, mood swings, headaches, depression (altho i have a history of depression/anxiety), joint pain in elbows, knees, wrists, ankles, neck and some bone pain in my wrists/hands, short-term memory loss/difficulty focusing sometimes but not always, sore hips/upper legs/back for about a week after each shot, fatigue, dry skin, decline in libido, weight gain.... gave it a 3 rating since im not even half-thru with the treatment but thus far its working and the side-effects are a necessary evil.... i got my first shot the middle of december about 2 weeks before my wedding (i know) and my first 3 month one mid-january my next 3-monther is mid-april, it was either this or another lap which i cannot afford. at first everything was going as expected, but after about 2 weeks my period and the pain hadnt stopped and had actually been getting worse. the nurses said that wasnt completely unheard of - i found out very soon there were a lot of things i wasnt informed of, i was told the side-effects would be menopause-like and minimal hmmm....oh well. after my period finally stopped the pain dropped off almost completely at around 3 weeks, but then the side-effects started: extreme hot flashes and mood swings, depression, fatigue, dry skin, etc. the hot flashes were the worst part, at least one an hour lasting anywhere from a few seconds to a few minutes and waking me up in the middle of the nite sweating. the headaches were nearly unbearable some days, i would just have to put my head down F 20 7 weeks
1/27/2009
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 2  endometriosis hot flashes, back pain, mood swings, joint pain It is not helping me. I have taken 4 months worth of it and I am in more pain than I ever was. My doctor has no explanation. I think it might be the hormones I am on on top of the Lupron. I have had 2 laparoscopies and have actually been diagnosed with endo. F 29 4 months
1/26/2009
 4  post op endometriotic cysts removal i experienced extreme hot/cold flashes, depression, bad acne, muscle and bone aches, headaches, extreme fatigue, loss of libido, loss of natural lubrication, mood swings, irritability, confusion, some memory loss During the first 3 months, i experienced extreme hot/cold flashes, depression, bad acne, muscle and bone aches, headaches, extreme fatigue, loss of libido, loss of natural lubrication, lost a few pounds. After the 3rd month most of the side effects subsided. I only suffered from depression, fatigue, confusion and disorientation/memory loss for the remaining 3 months. I got my period 2 months after discontinuation of lupron and gained 10 pounds coming off it! My periods so far have been pain free and i am no longer experiencing any of the side effects. Did anyone else gain weight coming off lupron? F 23 6 months
1/25/2009
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 3  stage 3 endo JOINT PAIN, EXTREME LOSS OF SLEEP, EXTREME MOODS SWINGS, HOT-FLASES, EXTREME DEPRESSION, MEMORY LOSS, ANXIETY I STEPPED INTO THIS TREATMENT WITH WHAT I THOUGHT OF GREAT SELF CONTROLL. MIND OF MATTER IS WHAT I TOLD MYSELF. WELL, THATS IMPOSSIBLE IF YOU'VE LOST YOUR MIND. MY PAIN AND PERIODS WENT AWAY IMMEDIATELY AFTER THE FIRST SHOT. ALL ACCORDING TO PLAN BUT THEN THE SIDE EFFECTS CAME. HOT FLASHES IMMEDIATELY, EXTREME HUNGER, AND EXTREME ANXIETY. BY THE 2ND WK ON MY FIRST SHOT I WAS CRAWLING OUT OF MY SKIN. I DIDNT KNOW WHO I WAS. I WAS CRYING ALL OF THE TIME AND EXTREMELY ANGRY WITH THE WORLD. I HATED MYSELF FOR FEELING SO WEAK N NOT BEING ABLE TO CONTROLL THIS DRUG. I HIT A STATE OF EXTREME DEPRESSION AFTER 1 FULL MONTH OF NOT SLEEPING LONGER THAN 2 HRS A NITE. I RECOMMEND THAT YOU HAVE A GREAT SUPPORT SYSTEM AS YOU STEP INTO THIS TREATMENT. I WOULD NOT RECOMMEND THIS DRUG IF YOU HAVE HISTORY OF DEPRESSION. THIS DRUG HAS BEEN A HUGE RISK TO MY LIFE. IT KILLS YOUR SELF-WORTH AND STRENGTH. THE ONLY GOOD THING IS THAT MY STRENGTH TO SEE THE LIGHT AT THE END OF THE TUNNEL CAME ABOUT 2 MONTHS AFT F 27 4 months
1/25/2009
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 3  Almost Stage 4 Endometriosis Just received the shot yesterday. I just came upon this site when I was searching for information on Lupron. I am very concerned now. I got the shot yesterday, it was my first shot. I had laperoscopy a little over a year ago, where I was told I had almost Stage 4 endometriosis. My husband and I want more children, and I saw a different doctor yesterday that suggested this shot for 7 months, then afterward we can try to have a baby. I am curious as to if anyone conceived after this shot? I am concerned after reading about this drug if I made the right choice. F 32 2 days
1/22/2009
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 5  endometriosis hot flashes, weight gain, less energy, constant sweating LOVED IT..despite the side effects Lupron was wonderful!! My life was back to normal while on Lupron..no more terirble periods F 34 6 months
1/16/2009
 1  Endo Pain, hot flashes, mood swings, loss of sex drive, nausea, developed a bleeding disorder I would not recommend this drug to any woman needing it for endo. I had nausea, mood swings, hot flashes, extreme pain, loss of sex drive, vomitting, head aches, and 8 weeks after my last dosage I was diagnosed with ITP - a bleeding disorder caused by the Lupron having adverse effect on my immune system and making my immune system attack the platlettes in my blood cells. My last dose was in April 2008 and this bleeding disorder is something I still deal with. During my 6 months on Lupron, at 3.75 mg per dose every 28 days, it was not as effective on my stage 2 endo as my doctor had hoped it would be, and recommended an additional year of Lupron (until I told him to go to hell). I still deal with pain from endo on almost a daily basis, sex is very painful, and I am waiting to have a hysterectomy... at the ripe age of 25... no kids in my future. F 25 6 months
1/13/2009
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 4  Endometriosis Hot flashes, mood swings, anxiety, weight fluxuation and night sweats. I was in a lot of pain with my endo, and I was desperate to find anything that would make my daily life more comfortable, especially during my periods. They were lasting for a month or two at a time and were excruciting enough to put me in the hospital. The shots made me feel pretty crappy at night, and I got very frequent hot flashes. However, I am pain free now that my 3 months is up. The worst side eefect for me came after my shots stopped. I have been off for three months, and I am now on anxiety medication. My doctor said it could be from the shot, or a combination of that and my job, which involves working with victims of crime. Overall, it was probably worth it. Haven't had a period for 45 days now. Don't know if it is the shot, or if our efforts to get pregnant are finally working. Overall, the benefits outweighted the risks... F 21 3 months
1/12/2009
 4  endometriosis Hot flashes, headaches, mood swings The pros definately outweigh the cons. I was a newlywed when I was diagnosed and I had horrible pain with intercourse before I began my injections. A month after I started Lupron I had no pain. The day or so after I get my injection I feel kind of cruddy and get a pretty bad headache. I also have hot flashes everyday and mood swings. All of these side effects are definately worth it. I feel so much better! F 20 5 months
1/8/2009
 4  Stage 3-4 Endometriosis Side effects kicked in after 1 month or so: headaches (controlled with advil or coffee), slight weight gain (controlled by diet), mood swings (short temper and crying jags), hair loss, a few hot flashes I get an injections once every 3 months. The s/e didn't really kick in until 3-4 weeks after the shot. Headaches only lasted 2-3 weeks and I could control them with meds, coffee, or staying super-hydrated. I can't answer for sure if this has worked or not b/c endo is tricky like that, but so far, I haven't been as miserable as I thought I would be! F 29 2 months
1/7/2009
 2  Possible Endometriosis I took it three days ago for the first time. By last night I was nearly suicidal. I was able to take Seroquel which had been prescribed for me for sleeping and it did the trick at least with the overwhelming depression. I've had depression before but not like this. I'm still feeling cramping like I did before the Lupron but time will tell if this will help. I'm bi-polar and cannot take the add in of estrogen or progesterone because of a history of blood clots. I'd suggest to someone who is bi-polar to really think hard about taking this or with the first suicidal thought to get in touch with their psychiatrist IMMEDIATELY! F 32 3 days
1/2/2009

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