LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  stage IV endo many many hot flashes, depression, mood swings, crying jags Even though I had never been confirmed as having endo, my mother had it, and I have looked forward to the day of my hysterectomy since I was 15 years old. So finally, at the age of 35, as a result of severe pain and a desire to finally have a child, I finally went to the doctor. In an effort to conceive, and reduce endo, dr. suggested lupron after the surgery to reduce the return of endo. I fully understood that neither surgery or lupron can or will "cure" endo. After 5 1/2 months of lupron, the vaginal ultrasound showed all the cysts had returned. So 2 1/2 years after child's birth, almost exactly 4 years after 1st laparoscopy, the pain from cysts have returned to original presurgery level. Was lupron worht it? no, i think that the surgery itslef helped more, at least for conceiving, removing cysts from both ovaries and fallopian tubes. Apparently, it didn't keep cysts from returning or growing during that "forced menopause". F 38 5 months
3/23/2007
 4  Endometriosis MIGRAINES, achy bones, anxiety, break-through bleeding, vaginal dryness I haven't been on this drug long enough to know the long-term affects, but as for right now it is a heaven send. I have had a constant headache since getting the shot, and there have been 2 days so far (not consecutive) that I began to bleed out of no where, and then the bleeding just stopped suddenly. I do feel a little achy, especially in my back, but nothing severe. I can say that the affects I am suffering are worth the pain being gone. Before Lupron, I thought I'd never be able to live without Vicodin. I have not suffered weight gain or loss due to the shot. I have lost a little weight, but that was only because I started working out and put myself on a diet. So Lupron had no affect on me in that department. The vaginal dryness is quite irritating, but compared to bleeding for 60+ days, it's not all that irritating. You just have to take the good with the bad, and make the call based upon your own judgement, not anybody elses horror stories. ~GOD BLESS~ F 33 11 days
3/22/2007
 5  endo hot flashes, some fluid retention I take a monthly shot and have been on Lupron for 5 months, have 1 more month to go. My endo was reduced by 50% at 3 months. I read this site and was very frightened to take the drug but am glad I decided to try it. Worked well for me. F 37 5 days
3/20/2007
 3  endometriosis This is the second round for me. I took it about a year and a half ago and had amazing results. This time has been hell. I am always sick to my stomach. The depression is overwhelming. I could sleep all day every day. I put on 10lbs with the first shot and had to get back on it because I kept bleedind. Now I almost over night gained 10 more lbs. I eat the exact same as I always have, which is pretty healthy. I am also retaining more water than the Titanic. I am about ready to get off of this. I don't know why my body reject it this time. I am so sick of feeling like crap. I am exercising, which definetly helps. I just can't handle the depression this time. It is starting to take over my life. F 29 7 days
3/14/2007
 1  To shrink fibroids pre-surgery Hot flashes, night sweats, shortness of breath, loss of focus/memory, severe anxiety, depression & suicidal thoughts, severe insomnia, fatigue, weakness, loss of apetite, nausea. Lupron helped with surgery for a very large fibroid. But the side effects were intolerable, I have never been so unwell in all my life. I landed in psychiatric emergency with suicidal thoughts and severe anxiety. Lupron made me feel insane, anxious and depressed and I was on Ativan as a result. I was frightened while on this drug and worry about long-term effects. Lupron continues to affect me almost 2 months after my last dose, though it is getting much better. I found alternative therapies (Japanese accupuncture and Chinese herbs) to really have helped. I was told by a nurse and by my accupunturist that Lupron can be hard on the liver and sometimes the body has a hard time eliminating it. Good luck to everyone who’s suffered on this drug. AVOID LUPRON or at least be fully warned about its possible side effects. BTW my doc was very sympathetic & did not dismiss my nasty experience. Poss of getting estrogen if things don’t get back to normal soon. F 39 2 months
3/7/2007
 5  Severe endometriosis with cysts Nothing bothersome. Very mild hot flashes. Mild vaginal dryness. If I were sexually active, I might to ask a doctor for a special lubricant, but I'm happy to have less discharge. I also have less acne. I had almost no pain from the endometriosis until cysts started to leak, so I was very reluctant to take a drug with such a long list of possible side effects. But now a week after injection #4, I still feel fine. If your endo is mild, there may be better options for you, but 2 different doctors recommended this drug for me, to prevent the cysts from recurring after surgery. After 3 more months I'll go on something else. It's not a cure, but whatever helps, I'm happy with. I get a lot of exercise, healthy diet, and good supplements, so that may help. F 35 3 months
3/6/2007
 5  Severe endometriosis with cysts Nothing bothersome. Very mild hot flashes. Mild vaginal dryness. If I were sexually active, I might to ask a doctor for a special lubricant, but I'm happy to have less discharge. I also have less acne. I had almost no pain from the endometriosis until cysts started to leak, so I was very reluctant to take a drug with such a long list of possible side effects. But now a week after injection #4, I still feel fine. If your endo is mild, there may be better options for you, but 2 different doctors recommended this drug for me, to prevent the cysts from recurring after surgery. After 3 more months I'll go on something else. It's not a cure, but whatever helps, I'm happy with. I get a lot of exercise, healthy diet, and good supplements, so that may help. F 35 3 months
3/6/2007
 2  endometriosis hot flashes weight loss constant spotting mood swings I have been on lupron for about a month and a half now. I have had to continue with the nuva ring along with the shot to control constant spotting. The first month I was spotting all month, had a full period when I took the ring out, and am now finally not spotting the last two weeks. The reason my doctor placed me on lupron was that it would supposedly put me in a temporary menopausal state to "starve out" the endo. Obviously when I am spotting and having full periods on the shot and on the nuva ring, this is not working. I have also been having severe cramping during all this as well. I had laproscopy done in early 2002 and had a big success with that. My cramping never went away but it was much more tolerable. I didn't miss school, work, or social functions anymore. But through this past year, my symptoms have returned. I was told that lupron had the same success rate as laproscopy, but this isn't proving to be the case for me. I have made another appoin F 24 1.5 months
3/6/2007
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 1  Endometriosis I am writing this for my 17 year old cousin Breanna. She is experiencing at the moment: extreme insomnia, severe memory loss, hallucinations, migraines, weight loss, high blood pressure, extremely high pulse rate, many more; has been diagnosed with lupron induced psychosis This drug needs to be taken off the market NOW. If you are reading this and are thinking about getting this drug, listen to me now. My little 17 year old cousin is in the hospital at this moment and my family does not know if she will ever recover. She does not remember something she said 30 seconds before. She is having hallucinations of voices telling her she is dying. She can not communicate with us, like telling us where her pain is. There are so many side effects of this drug...not to mention, the doctor who gave her the injection will not contact us back and has not sent us her records. DO NOT TAKE THIS DRUG! If anyone else has had these side effects or no someone who has, please contact me and give me advice on how she needs to be treated. Her doctors are stumped. F 17 25 days
3/6/2007
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 3  Endometriosis Severe headaches, depression, anxiety and panic attacks, drowsyness, low energy, strong hot flashes, loss of memory, upset stomach, palpitations. is true that it's helping me cure my endometriosis and in fact I haven't been at the ER for severe pain killers for my cramps since I started with Lupron, but maybe the side effects outweight the benefits, I'm 2 weeks away from my 2 shot and I'm having second thoughts, because I wake up and go to bed with an everlasting headache, I'm eating everything in sight and everything gives me an upset stomach (mylanta and pepto bismol are now my best friends) my back hurts, I feel depressed most of the time, I cry for no reason at all, I have palpitations followed by a panic attack so I'm strangely afraid to leave my house, I can't remenber the last sentence I just said, and I sweat horribly whenever I have a hot flash (every 30 to 40 min, and last about 2 to 3 min). So if you really really need to take lupron go ahead, couse it does work, but be prepared to face uncomfortable side effects. I'm still trying to stay positive and optimist about the outcome of my treatment but I have to tell you i F 20 9 weeks
2/26/2007
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 2  Severe anemia due to large uterine SEVERE headaches with vomiting, hot flashes, horrible "Flu-like" symptoms, stomach cramps, leg cramps, fatigue, almost constant dizziness, and skin rash. I was so sick when my cycle came on - I almost went to an emergency room. I will not take a second injection. I can not even function to take care of my children or to work. F 46 1 months
2/18/2007
 3  Fibroids Moderate hot flashes. Minimal mood swings. No weight gain or loss. Severe leg and joint pain. I am in my 5th month of Lupron. When the joint pain persists I realized it was not a normal osteoarthritis flair up for me. Other joints became uncomfortable. It was hoped that I remain on Lupron until menopause however I will not continue if the hormone add back therapy does not resolve the joint and leg pain I am experiencing. F 53 5 months
2/14/2007
 2  endometrosis hot flashes, night sweats, bone pain, memory loss, raged mood swings, weight gain, urinary tract infections, vaginitis, no sex drive, depression, feeling dazed, breasts shrunk 1 size. I could just cry thinking about these last 6 months of taking this lupron drug. It not only caused a lot of side effects, but it really put a damper on my family life. the bone pain was so bad. i did not have a lot of energy and if i didi used it to clean. my mood swings were so bad and i felt so bad for the kids seeing me like that. My doctor kept on telling me tht the side efffects should go away, but im dont with the shots and im still having night seats, mood wings and bone pain. i i wish i wouldnt have taken this drug. ive gained like 20 pounds. now the doc has put me on the pill everyday so i continue to not get a period. please be careful and really read all the information about the drug. good luck and i hope you get better results with this than i did, thats if you decide to take the drug called lupron. email me if uyou would like to chat about this. F 33 6 months
2/11/2007
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 1  endometriosis, ovarian cysts night sweats, memory loss, anxiety, bone loss-osteopenia. bad back and hip pain. Had lupron once a month shot for treatment of endometriosis( and hopes that is would help me get pregnant-dc said it would increase my chances after treatment). I did not initially experience really bad side effects (except for bad ovarian pain) but after the 4th shot it all went down hill - bad back and hip pain, night sweats, memory loss etc.. I went to doctor for bone density test (i ordered it myself) and now have osteopenia and taking a lot of calcium and vitamin D supplements each day (citracal with minerals). I had severe bone loss - hopefully I pray that it reversible!!! I was supposed to do 6 shots in total but needless to say I'm stopping with this one. This drug is not good and doctors really downplay the side effects when trying to get you on the drug. I can't wait for it to leave my system so I can be normal again. F 27 4 months
2/7/2007
 2  Endometriosis Severe Psychological distress (depression & anxiety), weight loss, hot flashes Just about a drug induced psychosis. For me, it did NOT work significantly. My pain remained, but it did reduce some of the bleeding from the lesions. Will never, ever take again. Medication was taken in 2000-2001 when I was 22/23. F 29 6 months
1/31/2007
 3  fibroids/major blood loss-anemia horrible headaches,major weight gain- my stomach looks like I am 5 months pregnant,joint pain,I can sleep all day if I did not have to go to work, feel like my insides are falling out,nausea,blurred vision,numbness in hands, hair loss, Let me say this regardless of the side effects I did not have a life before Lupron. For the last 2 years I was afraid to leave my house when my period came on the bleeding was so excessive. My gyn started talking about "transfusion" because of the blood loss (anemia). The first step was to try Lupron and go on iron pills. Well the lupron stopped my period and the iron pills helped with the anemia. I am scheduled to have another ultra-sound this tuesday to see if the lupron as helped. If not then the next thing will be surgery. I will wait and see what the future holds. F 50 6 months
1/26/2007
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 5  Severe Endometriosis and Cysts Hot Flashes, loss of Bladder Control, increased appetite, and shoulder and backaches Recently started my second Lupron session, and will remain on it at least 2 years. I truly believe it is heaven sent. My first Lupron round 3 years ago (lasting 6 months) was a complete success!!! Although I suffered numerous side effects, they were no comparison to the constant and debilitating pain which previously controlled every aspect of my life, especially motherhood. My symptoms began 11 years ago, and have continuously worsened (except during my pregnancy). I have had 3 Laparoscopies, 1 Appendectomy (my appendix was not infected, rather enlarged and they believed this may have been be a contributing factor), a Colonoscopy and a Bladder Hydro-distention in just under 4 years. In addition to surgical procedures, I have tried every birth control under the sun with no success. While a laparoscopy has the best success rate, my doctor, also a Gift from God, and genuinely concerned for my overall health and well-being, concluded it was not a practical route to take, and it was F 27 3 weeks
1/2/2007
 3  endometriosis Memory loss, mood swings, depression, boughts of unprovoked crying, extreme headaches, gassiness, irritability. I don't know how or why, but since I've been on this treatment, I find it very difficult to be around a large group of people, even family. I get anxiety and begin to sweat and feel lightheaded. Very strange. F 19 4 months
1/2/2007
 1  endometriosis I haven't started the drug yet but from the way it sounds its not a very good drug! Is the weight gain really that bad? F 23 0 days
12/25/2006
 1  Edometrosis In the beginning it was weight gain 47 lbs, severe body pain, leg cramps, hot flashes. But it has been almost 10 years and I am STILL SUFFERING!!! It destroyed my health; my body. I live wtih horrible pain in my body on a daily basis!! DONT DO LUPRON!!! IT IS NOT WORTH IT!! IT DESTROYED MY BODY AND MY HEALTH!! F 33 6 months
12/11/2006

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