LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Endometriosis Some weight gain Night sweats Some mood swings So far this drug has helped immensely, no more painful periods, no more periods for three weeks out of the month, and the side effects that I was terrified of are almost non-existent. I was afraid from reading sites like these, but I think part of the problem is people like me, who are loving what the shot is doing for them, don't take the time to express their thoughts. Yet the people who have had difficult experiences want everyone to know about it, so they post. Be cautious, read up, but don't always take other peoples experiences to heart. Everyone is different and will react in a different way. The slight negative side effects I have experienced so far are well worth the positive side effects I listed above. My quality of life is so much better than it has been in three years. I am taking the shot twice (1 shot every three months) and my second shot is scheduled for next week. I am slightly nervous again, in case any other side effects pop up, but other than that, I look forward to the continued relief that this affords me from my endo. F 24 3 months
8/11/2005
 1  ENDOMETRIOSIS Weight gain 60lbs, in one year and not able to loose, night sweats, hot flashes, mood swings, horrible acne it has been almost two years since my course of treatment and none of the symptoms have subsided. I can't loose the weight i gained with it,which is 60 pounds. I have had horrible cysts acne wihtout any relief when taking rx for it. Night sweats every night, hot flashes. And the mood swings have reaked havic on my family. F 28 30 days
8/8/2005
 2  Aid in invitro fertilization The first two times i did ivf i experienced weight gain and hot flashes. After the failed cycles i was able to lose the weight pretty quickly and the hot flashes went away as soon as i stopped using it. This time, I am not having hot flashes, but I did gain weight again and after two weeks of using Lupron I have a persisent headache. Mood swings and extreme sensitivity (crying for no reason) are also mild side effects for me. The side effects suck, but the desire to have a baby is stronger than the temporary suffering for me. F 36 3 weeks
7/10/2005
 1  ENDOMETRIOSIS My side effects happen every month about 2 weeks out from my periond I would get very bad lower back pain. I could not stand it, it would feel as if someone was beating me in my back. then when my period came my back pain felt worse and then when my period came it felt like my insides were falling out. Lupron is the most intense drug I have ever taken and would not take it again. I got the hot flashes right away, headaches, vomiting, hair loss, my mouth taste like pennies. My Doctor said she has never heard anything like this so she sent me to the ER to get lab work. The ER doctor said I was not an emergency so I had to leave. My doctor will not return my calls. I call every day atleast 5 times a day.. Hmmm must be nice to be a doctor to get paid the money they do and not follow thru. If it were up to me NEVER AGAIN. Im just lucky I have a paitent husband. Oh did I mention I can cry just like that. Think about what you are doing. all the research I did I should have not done this to myself F 28 2 days
7/1/2005
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 4  Endometriosis Memory problems, weight gain, fatigue & mood swings I read all the comments/reviews on the internet before I decided to take Lupron. I was very concerned with all the negative reports I read, but my choices were limited as I couldn't afford a laproscopy. My doctor and RN assured me that most women have little to no symptoms, so I went ahead with it. In the beginning (the 1st shot), the endometriosis symptoms got much worse (this to be expected), I was extremely tired and weepy. After about 3-4 weeks, I seemed to adjust to the medication. Since then, I've been pretty amazed at how little symptoms I've experienced. Probably the most irritating are the memory lapses and the weight gain (I can't lose it no matter how much I workout or eat healthy). I'm in my 6th month of the Lupron and am hoping that once it's done, everything will be normal. F 31 6 months
6/10/2005
 1  Adenomyosis, Endometreosis Headaches, hot flashes, insomnia, constipation, mood swings, depression, burning skin, itchy skin, bloating, fatigue, memory issues - have to keep everything in a calendar now. I am supposed to get my 4th shot next week. I get it once a month. However, last Friday my period started again. At first it was a little light, but now at 7 days, it's heavier. I also am experiencing major cramps and bloating. I have a hysterectomy scheduled for July 13th. I'm totally unhappy on Lupron. I tell my doctor each month that I don't want it and he claims I need it. Now, I have all the side effects plus my period. I called the doctor and they said that if the bleeding doesn't stop they'll put me on estrogen. So - they've stopped my estrogen with a drug with lots of side effects and now have to give me back estrogen (with lots of side effects). Avoid this drug if possible. I feel like it's really thrown me for a loop. F 37 3 months
5/20/2005
 3  adenomyosis muscle pain, severe headaches, hot flashes, night sweats, mood swings, weight gain Lupron is not a wonder drug, as the manufacturer claims. It can be helpful in situations where other drug therapies have failed and the patient wishes to avoid or delay surgery. It has stopped the pain of adenomyosis (think labor pains) for me, so I cannot wholly discount the drug's usefulness, but anyone considering using Lupron should be well aware of all the possible side effects. I was warned of hot flashes and vaginal dryness, nothing more, and I now wish that I had taken the time to look into other possible side effects. The worst of the side effects for me are the muscle pains and awful headaches, both of which I might have been able to prepare for had I known they were coming. Also, sadly, the weight gain puts me further away from surgery than I was before I had the injection; if you are considering Lupron as a pre-surgical therapy, keep in mind that it can have adverse effects on your surgical risk factors. Lupron will likely do you some good if you are in pain due to hormone-driven diseases like endometriosis, adenomyosis or fibroids. However, I strongly suggest that you make sure you know exactly what you are getting yourself into before you take the leap of faith with an irreversible three-month injection. F 28 2 months
5/14/2005
 3  endometriosis,ovarian cyst,pain i get hot flashes and headaches weight loss night sweats mood swings i like the shots but my case is so saveer that i need them sooner than once a month. My doctor wont give them to me sooner but it sure would be nice if she would. iv been living with ovarian and uterian pain since i was 10. since iv been taking the shots my pain has gone down and made my life a little more managable tell i have my hysterectamy F 28 9 months
5/8/2005
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 4  Stage IV Endometriosis Hotflashes; nightsweats I originally went into the hospital because they found a cyst on my right ovary. After the surgery (laproscopic) it was determined that I had severe endo and probably had it my whole life. It was decided at that time that I would do a 3 month course of Lupron followed up by a full abdominal hysterectomy. I just received my 3rd shot today, and the only side effect that I have experienced at all are hotflashes/nightsweats. I have a previous history of anxiety and depression. I also suffer from a weight problem, so after reading much of the feedback from websites I was very nervous about losing my mind and gaining tons of weight once on Lupron. I am pleased to be a positive light on the use of this medication, because I have found it very beneficial. In fact, I never realized how miserable I was until I began the injections and started feeling better. As I have never tried to get pregnant and have always lived my life with heavy periods lasting more than 10 days each month accompanied by severe pain during ovulation and terrible cramps throughout, I am so glad to be rid of all of my pain and the bloated feeling that I have always felt is gone. Even though I have been conscious of what I have been eating while on the medication, because I was nervous of gaining weight, I have actually lost weight (approx 15 pounds in 60 days) without eliminating an occasional piece of cake or dish of ice cream. My surgery is scheduled May 20th and I am turning 40 tomorrow and I am feeling like I am beginning a whole new pain free chapter in my life and can't wait to find out what the end of this journey has in store for my well being. I certainly don't want to discredit anyone's personal experience on this drug, but after almost making the decision NOT to take this medication because of what I read, I felt it incredibly important to add my positive experience. The hotflashes are frequent (15-20 per day), but certainly not debilitating and they don't last for more than 2-5 minutes. I have not suffered from any anxiety, headaches, weight gain, hair loss, or insomnia, all of which I feared if I took this medication. I also had a spinal fusion 14 years ago so I was nervous about the bone density of my fusion being deminished by the medication but my doctor said that the Lupron would not have any effect on the strengh or stability of the bones. I don't believe that I am a person with a high pain tolerance or a person who handles not feeling good well, however, from my personal experience, I FEEL GREAT! I decided to take the monthly injections so that if I had any adverse reactions I could have the choice to stop after each month. I expressed all of my fears and anxieties with both my OBGYN and my regular doctor. They both took the time to give me their professional opinions related to my concerns. They told me that the potential for side effects were possible, but that the majority of the people who take the medication, either for endomedtriosis, fibroids, or prostate cancer, had no serious adverse reactions beyond hotflashes and possibily some headaches. Every person has to make their own decision, but know that there is a person out there who is glad that they took LUPRON. F 39 3 months
4/28/2005
 3  Fibroids Wieght Gain Sleepless nights Hot flashs Head Achs Mood swings Loss of Sexual Desire Bone Loss Hair Loss Consider very carefully before takeing this drug. It is not a short term medication. It puts you in a whole new state of life but does however work well in reduceing and shrinking endrometriosis. I have been on this twice and no more. F 46 2 years
4/20/2005
 4  fibroids hot flashes, bone pain, headaches This was able to shrink my huge fibroid considerably and I was able to have a vaginal hysterectomy instead of abdominal. I feel like it was a success and it is 2 weeks after surgery. F 46 3 months
4/14/2005
 1  Fiborids Extremely bad Hot flashes and Night sweats. bone pain, bone loss, more weight gain than I was originally getting from the fiborids, couldn't sleep, and other problems. I made a point of letting the doctor know that I did not want a histerectomy. I went to him because I was told that he had done remove other people tumors without them having the surgery. I ask him if he could do anything else, he said he would put me on the Lupron and that would shrink it. I had no idea what this medication was other than it was suppose to shrink the tumor because I was never told anything about it. He would order it at the pharmacy the morning of my appointment and have me pick it up and bring it to the office with me and than the nurse would mix it and give me a shot. i was on this medicine for 4 to 5 months. Each month I had a shot. Each time that I would have the shot I would pick up weight, almost looking like I was full of fluid. The first shot my period stopped completely and than the other problems started to occur. It felt like the fibroids were getting bigger and I definitely got bigger it seem like I gained 10 pounds each time they gave me a shot. I became weaker and worn out. I couldn't sleep and I couldn't lay on my stomach because it was getting larger because the fibroids was growing and getting bigger. I ask him before he gave me the first shot was there anything that I shouldn't do to incourage the growth of the fibroids he said no. By the second shot all the side effects I named and than some was occurring on the third shot the nurse ask me was I having trouble sleeping at nights and I told her yes and she said oh, thats just a side effect from the medicine. I had trouble getting up in the morning, my bones hurt and I was walking like someone who had a bad case of arthritis. I stayed ringing wet a lot of the times from the hot flashes and night sweats. After going through all this the doctor said to me after the fifth shot that the medicine did not shrink the tumor it did nothing for it. Of course he didn't bother to give me anymore test to check he just felt around on my stomach and said that it didn't work. If he had told me from the beginning about the side effects of this medications and that it was possible that it wouldn't work I wouldn't have taken it. Because he did the surgery anyway and I haven't been the same since. I had always been a very healthy person but since the medication and the surgery I haven't been the same since. This medicine has some extremely bad side effects and should be a persons last choice and should never be giving to anyone until the doctor sits down and explain the side effects because there will be side effects, some patients may not have the same side effect as the other one but once again there will be some. I know someone out there is going to respond by saying all drugs has some side effects but has anyone notice that every drug out there anymore has a list of side effects with them, side effects that will happen not that could happen. The difference is that years again a drug may have had a side effect or two but usually you didn't have them and if you did they weren't as severe. Now you fix your heart and destroy your liver or fix your kidney and mess up your bones just a example. Maybe we are trying to get these drugs on the market too fast and there aren't enough test being done on them before they are put on the shelves for consumers to buy. Getting better is what every patient wants but fixing one problem and making another one is not getting better. We are now robbing peter to pay paul with medicine anymore. Doctors need to let the patients know what may and may not happen and not expect the patient to find out on their own. I forgot to say that after I started experiences all those side effects I had to go to the computer and than I got a lot of magazines after everything was over to find out about the drug lupron and also what I could have done to help shrink my tumors and what I shouldn't have been during to incourage the growth of them but of course my doctor said that there wasn't anything, boy wasn't I misled. Of course, the doctors should also take responsibity for this problem because they should make sure each patient knows the advantage and disadvantage of taking a drug that they recommend since they suppose to know the history of that patient. Just because the medicine suppose to work, it may not be the best thing for that person. So please anyone who is offer this or any other drug thank about it before you just take it. Again, there is too many drugs out here now that has too many side effects meaning sometimes there's more harm done to you than good. F 49 5 months
3/24/2005
 1  Endometriosis Horrific and long lasting. Migraines, weight gain, osteoporosis, memory loss, cardiac issues, the list goes on. Don't believe the hype - the fans who tell you about Lupron being safe and tested and having no long lasting effects don't want you to know the truth. F 35 4 times
2/25/2005

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