LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  endometriosis debilitating bone/joint pain Please use this drug with caution. My last injection was over a year ago, and my pain is still severe. I have seen three specialists and have undergone extensive testing. They have all reluctantly agreed that the Lupron is causing my pain. F 31 5 months
11/12/2009
 1  prostate cancer spread to bones My father had three injections and became very fatigues and depressed. He took his life a month and half after the last injection of Lupron. He had a heart condition also and was given the drug anyway. It has been shown to cause cardiac arrest. THe nurse practioner at Thomas Jefferson Urology in Philadelphia, PA said she saw my father was depressed and she continued to give him the injections. She was not supervised by an MD which is permitted in Pennsylvania. Before the shots, father was walking around Philly. After he was too tired and depressed to do anything. Nurse also gave him Casodex which combined with Lupron severely lowers testosterone levels. Dr. Sui-Long Yao of Cancer Institute of New Jersey did a study that shows Lupron doesn't increase lives of prostate cancer people and seriously damages the quality of their lives. The Los Angeles Times newspaper reported those receiving Lupron had a 17.4 percent death rate vs. those not receiving it of a 19.9 percent death rat all of his teeth would have to be pulled because Zometa causes decay of the jaw bone. She said my father didn't want that to happen to him and she didn't refer my father to anyone else for chemotherapy when he asked if there was another course of treatment. She let him leave very depressed and tired from the Lupron and Casodex. The supervising doctor, Dr Goldman, of the nurse practioner, nurse Darlene Bewick,said to me he didn't know about my father's care because the nurse saw him. he didn't even know my Dad had bone cancer from the prostate. Do not take Lupron. It causes severe damages and has caused my father's death. Doctors keep giving the drug. Please email me: Cheryl. M 88 4 months
11/8/2009
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 4  Endometriosis Hot flashes, real bad muscle aches, nausea, headaches, mood swings, fatigue. I had an ovarian cyst removed in May 2009, when the doctor found some endometriosis. Started having real bad symptoms of the endo in August, got my first Lupron shot at the end of September and I just got my second shot four days ago. I saw my college's health services today because I thought I had the flu, I'm so achy and exhausted, but I don't have a fever or anything so I think they're likely symptoms of the lupron. I am on the pill that came with the shot, take that every morning and I think its better with that because I missed one once and I was MISERABLE. I think I've had "hot flashes", in the sense that I sweat more than usual and sometimes feel very warm, but nothing like older women I know who are actually going through natural menopause. I feel TERRIBLE today, but I guess body aches is better than being doubled over in severe abdominal pain every other day? F 20 1 months
11/3/2009
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 4  Lower Androgen level mood swings, hot flashes, night sweats, headaches, nausea, light-headed, 1st month still got period I took 2 one month injections to lower my androgen (testosterone) levels- it was high for me being a female. After 2 months it was lowered and I am supposed to check it again soon, so hopefully this works long-term. All of the symptoms were relatively mild and not all the time. However, I felt pretty weird and out of it the whole time. I did a lot of research online and there are a whole lot of horror stories, but it really wasn't that bad for me. I lived with someone else who took it for inducing menopause and she had more severe symptoms. She was also on 3-month doses and said they stayed in her system too long. If my levels continue to stay normal long-term, this was well worth it and I would do it again, but not for any extended period of time. F 23 2 months
10/29/2009
 4  Fiboids Hot flashes. Mood swings. Spotting at first and then no period at all. Mostly hot flashes. I have a 17 cm fibroid. I am taking a 3 month injection to shrink the fibroid to Da Vinci operable size. PLEASE look into the Da Vinci surgery. The recovery time is 2 weeks and is much less invasive. Most doctors don't know how to do this surgery. Keep searching until you find one that does. F 34 6 weeks
10/18/2009
 1  Uterine Fibroids I started having hot flashes at the age of 32. Hot flashes, rapid weight gain, vision changes, acne, muscle and joint pain, extreme aggitation, heart palpitations, thoughts of causing others harm, short term memory loss, diagnosed with high blood pressure and arthritis, dizziness, shortness of breath, chest pains, looks like I am 5 months pregnant, and a daily migranes are all that come to mind at the moment. BUT I am sure the only reason I can't name more is because of the memory loss. Poison to body and soul. The temporary relief is NOT worth the long term suffering caused by Lupron!! I suppose the only thing that may make this nightmare worth it is if you are trying to conceive or you are being treated for a terminal illness. I am praying for all of us and even those that have read all of these posted warning and unwisely allows your doctor to convince you to alter your life forever. I only had fibroids and now I feel like an 80 year old woman. My daughter wants to know why I don't play with her anymore. Every day I have to tell them to be quiet because mommy doesn't feel good today maybe tomorrow. The Devil is a lie, I am going to play with my girls again. In the name of Jesus!!!!!!!!!!! F 45 3 months
10/12/2009
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 5  Endometriosis Joint Pain, weight gain, hot flashes I was on Lupron in 2001 for my endo pain and i LOVED IT! My pain was gone and although the side effects weren't fun it was worth it. I had a son in 2004 and 2006. I started feeling endo pains last year and I talked to my doctor about another round of lupron. I just got my 1st 3 month shot this week and i am excited. Think about it - i got the shot in 2001 and started feeling pain again in 2008? Seven years of relief! Lupron is wonderful and I say try it! F 29 6 months
10/9/2009
 3  Anomiosis and Stage 5 endo I gained weight, always tired, horrible horrible mood swings, anxiety, depression, always crying, bruise easily, acne wich I have nver had in my life. I am 21 years old I started the lupron injections five months ago because I have anomiosis amd endometriosis.I have been sick since i was eleven. I have had five surgeries nothing has helped so lupron was the last thing to try. I am on a low dose of it. I absolutly hate it. I thougt i was getting better but this month which is my 5th month is bad Im in costant pain. Im very emotional. I just feel so slow and depressed. Im only on it another month Im just wondering what happens when I go off. F 21 5 months
10/9/2009
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 3  ENDOMETRIOSIS-PCOS MIGRAINE, JOINT PAIN, BLOATING I have taken 1 3 month shot and due for my second. At first, my symptoms of endo were really bad if not worse then I have noticed in the last couple of weeks that the pelvic pain is gone but the joint pain and abdominal bloating are my biggest problems now. I had a couple of migraines the first month but none since then. over all I think Lupron has helped with my endo but I am now concerned about joint pain and the swelling of my tummy. I plan on seeking advice from an endocrinologist (not sure if I spelled that correctly) since I have PCOS as well. Also will be making an appointment to see a gastroenterologist to check out the bloating. F 35 3 months
10/5/2009
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 1  endometrosis/ pelvic pain I only got the shot 5 days ago and i am experiencing many side effects. Hot flashes and cold sweats started the day after. I have been very dizzy i can get half way through straightening my hair and have to sit down. I have ate 1 can of chicken noodle soup,6 saltine crackers, and a half a sandwich in the last 5 days. I have also had a very very bad headache the last 5 days. I have missed two days of work this week because of how nausiated i have felt which started the day after the shot was givin. This was only my first shot and i am already having so many problems with it. I dont think i am going to continue getting these injections because i am afraid the more i put into my body the worse it will get. F 20 5 days
10/4/2009
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 1  severe endometriosis Debilitating joint and bone pain. After taking 1 three month injection of Lupron, I have since been diagnosed with Rheumatoid Arthritis and the blood disorder Polycythemia Vera within a year. It did stop my cycle for 6 months so I did have temporary relief from the endo. I do not recommend this drug to anyone. Even with an add back. Especially anyone that already has a anti-inflammatory disorder or disease. I never experienced such adverse side effects from a medication until Lupron. Horrible. F 36 3 months
10/2/2009
 1  endometriosis Hair loss, memory loss, severe hot flashes I will say that after I was off Lupron, I got preganant 5 months later. However, I would NOT recommend Lupron. This drug put me into early menopause the second I got off it. My docs have said that my body is actually 15yrs older than my age. I have very little short term memory, my hot flashes have never gone away and my last shot was 18 yrs ago. Now my daughter has started having hot flashes at the age of 14 and strongly believe it was because of the Lupron still in my system. I had endometriosis so bad that the doctors filmed my surgery and took it around the world for training classes. Ladies, get the hystorectomy!!! Yes, you'll feel better, still lose your hair and so on. If you have endo, don't keep the ovaries because the endo will still live. All the pain is gone except for the side effects of the Lupron. Several years ago there was a class action law suit againt the use of Lupron. You had to sign up for compensation however all the news regarding this just stopped being posted. I gave up and figured I got my daughter and will just deal with the worst of it the way I always have. If you can survive ENDOMETRIOSIS, you can survive anything! Can I hear an Amen?? F 46 6 months
10/1/2009
 5  Endometriosis Hot flashes, easily irritated, more emotional I have to ask myself why I put off taking this drug for so long. My pain was so bad, I was miserable and my quality of life sucked. I rarely went out with friends and was no fun to be around because I was in constant pain. Within just a couple of weeks after the first shot everything changed. I feel great. I had forgotten how great it is to not deal with pain everyday. My doctor started me on the 30 day shot to ensure I could manage the side effects. I waited exactly 30 days to get the 2nd shot and 2 to 3 days before the shot I started to experience pain and other symptoms associated with my endometriosis. We opted to do the 3rd shot earlier and I experienced none of my previous problems. My doctor is only keeping me on a six month treatment and I can only hope that the medicine builds up and I get the years of relief that have been reported with this medicine. I can't imagine having to go back to the way I was before. I feel like a different person. I am able to go out and have fun with my frieds, I went on vacation, and get along better with my family. I consider it my miracle. F 31 60 days
9/29/2009
 5  Endometriosis I had experienced none of the side effects that was listed in the patient drug information. I guess the only side effect was pain relief!! I have nothing bad to say about this drug other than I would like to take it more frequently. it has done wonders for my pain, and I would do it again if the doc said I could. I did it for nine months. has anyone ever done it longer? I LOVED it. F 32 9 months
9/20/2009
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 4  shrink fibroids before hysterectomy minor headaches, weight gain, mild depression, fatigue, hair loss, hot flashes lupron successfully reduced the size of my fibroids allowing my hysterectomy to be VLAH instead of abdominal. this has been fantastic - today is 6 days post surgery and i can walk 2-3 km comfortably, have 3 insignificant incisions, very little pain and could reasonably return to a desk job within another 7-14 days. being informed of the side effects is important to be able to manage through them. my doses were 1 shot/month for 3 months. last shot 2wks ago - hair loss just started - i lost hair post partem also likely related to hormonal swing so it makes sense. 3 months
9/20/2009
 3  Endo, Fibroids Moodiness, weight gain, fatigue, depression, vaginal dryness (severe), decreased libido (significant), constant spotting, abdominal cramping I started taking this medication about 3 weeks ago. Since then, I have been spotting/bleeding nonstop - this has been the worst side effect for me so far. Some days it is lighter than others. I am always tired and very irritable. I had very little symptoms in the first few days of receiving the injection. Thankfully, my doctor also prescribed aygestin to help with the hot flashes and it has worked exceptionally well. If you are considering taking this shot, I would recommend asking the doc to prescribe something in addition to combat them. I hate the way it makes me feel most of the time and I cannot wait for the next few months to go by so I can be finished with it. F 26 3 weeks
9/10/2009
 3  Endometriosis Hot flashes, night sweating, severe mood swings, depression. I started taking Lupron two weeks after I had a laporatomy in December. I took six shots and told the doctor that i refused to take anymore. I was so moody and depressed that my husband was miserable, almost left me. I had to start taking Welbutrin for the mood swings after my second shot. All I did was cry. I took my last shot in May and did not get my first period since the surgery till August. AFter the period, I am having to take birth control non stop till I decide when I want to start having children. I would recommend the shots to anyone, but be sure you have a doctor that is very open with you and be there to answer your questions if you have one. If I had a question or problem, my doctor or his assistant always called me back and I did alot of research before I took the first shot. Also, I got some advice from some friends who had been on the shot and kinda knew what to look for. The only problem I am having now is that my legs and ankles started to swell in July. My left leg/foot is swelling worse than my right. I have been checked for several different things and nothing has been found. I am starting to wonder if it is a side effect for quitting the Lupron. If anyone has ever had this same problem after the last shot, please let me know. F 28 6 months
9/10/2009
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 3  Excessive Bleeding/Pain Hair loss, lots of it. migraines, decrease libido, vag. dryness, I havent had hot flashes yet, however, Ive only been taking this for one month. I still have grave concerns over what happens after the completion of this medication. And i really hope I still have hair left after this is all over with. Other than that I still think its working well. F 37 1 months
9/8/2009
 1  endometriosis Hot flashes, Lots of hot flashes, brain-fog, severe moodiness, Extreme forgetfulness, Weight loss, At the time was taking it -and up to a year later, I would have recommended Depo Lupron. It helped with the pain of endo. for the 1st time in my life I wasn't doubled-over in pain, and could be active! But the side effects still continue and the pain comes back. 7 years later: I'm VERY forgetfull/ memory problems, to the point it's cost me friendships and jobs. I suffer Joint pain, insomnia, occasional hot flashes, became very sensitive to chemicals and stimulants (such as caffeine, medications, food additives) With such complicated, long-term side effects and not being able to find a doctor who will look into what happened to me as a result of luron, the desperation now is worse than just the pain of endo. (plus pain/endo back too) I strongly warn against Depo Lupron!! If anyone has had similar problems with MEMORY and other long-term side affects please e-mail me with what's helped or info on Doctors who have looked into this. Thanks F 25 6 months
9/8/2009
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 4  endometriosis, ovarian cysts hot flashes, depression, weight gain Have LOVED not having a period for a few months. I've been virtually pain free! I don't know how long it will last once I'm off the drug but for now it's great. I've had 2 injections and hot flashes were the worst within the first couple of weeks after each one. But I have to say it's been worth it. The weight gain sucks, so I'm hoping to lose the 8-10 pounds over the next few months. I've been moodier than normal, but I learned to sort of "feel" when a bad mood swing was coming so I could take a few deep breaths or find another way to deal with it. In hindsight, maybe add-back therapy would have been good, but I didn't want to take any other medicine. I'm hoping this drug will buy me a chance to conceive. Aren't hot flashes and 10 pounds worth that? F 32 4 months
9/6/2009

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