LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Endometriosis Hot flashes. It was heaven sent within one month, years of pain subsided. I took two courses. The risk / benefits were well worth the sweating. No joint pain, hair growth (in fact, had more facial hair after I stopped injections). It helped delay a hysterctomy for two years. I now have to have one in the next few weeks. I wish a third course was possible. remember, the first month is Aweful. We can take control of our own mood swings, as long as we know its a problem. Family support and self education is a must. My Immuran is scarier than this. F 42 2 years
8/13/2007
 5  fibroids very hot all the time-had to keep the A/C way down and then I was fine I had the 3 month injection for fibroids and non-stop bleeding. I absolutely loved this medication! I felt great! The bleeding stopped, my moodiness and irritability went away completely, my family couldn't believe how much fun I was, and I had no sexual problems. The fibroid did shrink slightly, but more importantly, the uterus' inflammation went away completely and the overall size was decreased. Clearly this is what I needed and was sorry when the effects wore off. I am now facing hysterectomy, but just wish I could stay on this medication until menopause. F 45 90 days
8/9/2007
 2  prostate cancer HOt flashes, chills, weakness, body cavity aches, depression and the usual sexual problems, all severe and life altering. After my radiation implant, I have refused any further shots of Lupron. M 7 months
8/9/2007
 2  fibroids, anemia terrible hot flashes and night sweats, gained 20 pounds in five weeks without chanage indiet or activity. Depressed. F 38 2 times
8/7/2007
 3  prostate cancer fatigue, hot flashes, complete loss of libido/sexual function, mental fogginess, depression I'm taking Lupron to shut down prostate cancer while I'm doing external radiation therapy (this is followup to a radical prostatectomy because I had a 0.5 PSA level 6 weeks after surgery). It has been very effective at shutting down the cancer (PSA is undetectable after 1 month on Lupron) but the side effects are horrendous. Having no testosterone is brutal, I have lost my ability to focus mentally, have little drive or ambition, and have a complete lack of sexual interest or function (well, post surgery I already had erection issues, but now there is just NO response to anything sexual). I hope it will be worth it in the long run, but for now there are days when I'd rather let the cancer run its course than live this neutered existence. My oncologist says he will only use Lupron intermittently if the radiation doesn't put the cancer into long-term remission -- he understands how difficult it is to live with Lupron (and he says that if you use Lupron continuously you eventually have at M 47 2 months
8/3/2007
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 4  Endometriosis Before add-back I experienced terrible hot flashes. I also continue to experience mild mood swings, mild depression, difficulty concentrating, and a lowered sex drive. I will point out, however, that I have not had any bleeding and absolutely no pain! For me, the side effects have been totally bearable and if I could stay on Lupron I would. I believe that when you read a site like this you unfortunately get a filtered perspective because only people with very bad experiences are likely to go out of their way to post. If you have bad endo you should give the one month Lupron injections a try because if you do not have terrible side-effects, it is worth it 100% to stop the pain. I have taken 5 of 6 shots and would continue to take it if I could. F 29 5 months
8/1/2007
 3  Fibroids Mood swings, minor depression, anxiety, hot flashes, acne, lethargy Mood swings and anxiety throughout the whole treatment. No weight gain yet, but I am so stressed I am not eating properly. Hot flashes are extremely uncomfortable, especially in the summer. But I do feel that the fibroid has shrunk. First month had a 2 week long period, but since the second shot 2 weeks ago have not bled at all. F 27 6 weeks
7/31/2007
 1  fibroid hot flashes, memory loss ( I think ), huge tummy ( at least 4 inches increase), loss of period and dont know if it's ever coming back. I would never take this drug if I know the long term effect of it. I had surgery 10 weeks ago, my wound has healed but the side effects has not gone away. I had a 3 month shot of lupron in February. After almost 6 months, I still dont have my period. I'm afraid I wont be able to have children as a result of this drug. Originally it was suppose to shrink my tumor so that surgery would leave less scarring, therefore my chance of having a baby later would be better. Now, I'm starting to think that it's better to take your chance with the surgery alone. Find out more about this drug before you allow it to enter your body. Get a second or third opinion. Good luck.. F 33 3 months
7/31/2007
 4  pre-surgery for Fibroid removal Dizziness, Severe bone pain in legs and arm. Some memory loss but that may just be me being forgetful. loss of about 10lbs. No mood changes, No loss of sleep, No bleeding, No swelling. This will be my second surgery to remove Fibroids and my last. If they come back I am going for a hystorectomy. I will not opt for this treatment again. I just wanted the option to have kids in the next few years. I have also started taking Celexa again to fight against any depression or any anxiety I may run into. It may be all in my head but at least I dont have anxiety attacks(which I am prone to). Most of the descriptions on this site scared me. I was so afraid to get my first injection. It turned out to be not that bad. Barely any symptoms in the 1st month I noticed just two hot flashes. Then the 2nd shot about 2 weeks after that I noticed my legs and arms hurting. I can barely walk at night, it seems to be in my bones not tendons ot muscles. The pain shoots up my legs while walking and throbs all the time. Whats worse is I have to stand at work all day. I have a doc appointment in two days and we will see from there. Maybe I wont need a third shot and we can do the surgery soon F 27 2 months
7/30/2007
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 2  Endometriosis Hot flashes,mood swings,Night sweats,back/stomache pain,loss of energy,migraines I took my first shot on 7/18/07. The day after my 16th birthday. I am using the add back therapy. If anything, I feel worse. I cant tell if the pain from the endo is gone or not because of the side effects of the shot. 16 12 days
7/30/2007
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 4  Endo Mood swings, occasional headaches, some cramping in my lower stomach, some weight gain. I agree that this is not the best medication to be on but it is the only thing that works. I also recently upped my dosage of my vivell patch which really helps get rid of side-effects. I only have 4 more shots to go and then it's time to try and get pregnant! F 25 1 years
7/29/2007
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 4  Endometriosis Hot flashes, Racing heart, panicy at times, mood swings I used lupron for 6 months when I was 17. It worked great i had the typical side effects. When I agreed to take it i had no idea about all the horror storys! I have been endo free for 3 years! Ithas just now started to come back my Dr. wants be to do another round and then try to have a baby! I'm scared though! I don't want to tempt fate and have adverse reactions! I'm not sure yet if I will go for a second round! F 19 6 months
7/27/2007
 1  Endro I always research meds before agreeing to take them. I cannot tell everyone how much I appreciate all the honesty in taking this drug. You have just saved "one more person" from the pain and agony caused by medication. I have many other health issues which already cause alot of the same side effects. I cannot imagine adding to all of that. I recently had exploratory surgery and they found endro, but only a small amount, which was removed. Now they are checking my bladder, however.....the doctor is INSISTANT that I take 3 months of Lupron. After reading all your comments, I will refuse. It's not worth it to me. Thank you all! Once again, I'm glad I researched, prior to taking it. M 42 0 days
7/26/2007
 3  Endo and ovarian cysts Severe headaches, mood swings, fatigue, bone pain, and major hot flashes and night sweating! I'm going for my fourth shot next week and I'm really rethinking it. It definitely works for the endo pain, but the side effects are just not worth it. It's hard with three kids! F 30 90 days
7/25/2007
 1  pre-hysterectomy In my first month, I had a heavy period, mood swings, hot flashes, and felt like I always had to pee. In my third month I had another heavy period. Now, at the end of my fourth month, I have taken a leave of absence from my career because I have garbled speech, confusion, memory gaps, shakes, sleeplessness, and worsened depression. F 40 4 months
7/23/2007
 3  Endo Too early for me to say. I am hoping to have mild side effects but after reading all these comments I am concerned. I had my 1st shot on 7/19/07, so this is still all new for me. I am doing the add back therapy which is suppose to help with the side effects. I had the Lap surgery in May and it seems that my periods have got worse after the surgery so I am hoping for some kind of relief with the Lupron shot. I am really concerned after reading all the negative side effects of this medicine. I have also been trying for the last year to get pregnant with no success. So, I was told after 6 months of Lupron I should have a good chance. F 35 1 days
7/20/2007
 4  Prostate Cancer After the 1st shot in December of 2005 I experienced hat flashes, night sweats, fatigue and loss of libeato. However, at this time there are no more hot flashes or night sweats, the fatigue and loss of libeato continue along with some hip paine. The external radiation treatment and the lupron have dropped my PSA from 17 to less than .001. M 66 20 months
7/17/2007
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 1  Endometriosis I went to the gyn today and he basically made me feel brushed off. He wants to put me on Lupron for the endometriosis. I told him I felt it was a horrid drug with the research I have done and he said no it wasn't. I don't want to take it but I am tiered of this pain. After reading everyones comments I definately am going to refuse these injections. Thank you all for all your comments. Does anyone out there suggest anything elese for treatment I may not know about?Any info would be awesome!! Thanks F 26
7/16/2007
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 1  Fibroids, possible endo Run from this drug. I have had two shots. Everyday is like torture for me, am having seizure type incidents. I have had severe chest pains, elevated blood pressure and ended up with a cardiac catheter I did not need. I have had severe pains in my muscles, bones, shoulders. I have been dizzy, passed out, and in the emergency room six times since my second shot. I am a graduate student and I am having memory problems. I have had visual problems also. My abdomen is now horribly swollen and very painful.This drug is stressing me and my family out. We are horrified. Everyday I have an attack! This is torture. F 40 2 months
7/15/2007
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 1  Endometriosis Spasms in my muscles, from my head to my toes; hot flashes (helped with add-back therapy);joint/muscle pain; leg pain; major mood swings; dizziness; confusion; depression; headaches; inability to sleep; urinary symptoms; bowel problems; flu like symptoms; loss of appetite; loss of sex drive; break-through pain (such as Endo pain felt previously); fear; anxiety; feeling alone; vision changes; extreme water retention, to the point of feeling like I've gained 30 lbs (have not weighed self); lack of energy. This product has extremely effected my life. If I had known that I was going to react this way, I never would have done it. My family has been effected, my friends....My whole life feels like it's been turned upside down and I don't know when it will get back to normal. The side effects of this drug are not, by a long shot worth the slight relief of some pelvic pain. After my second shot of this, my pain came back! F 24 3 months
7/10/2007
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