LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Prostate Cancer I've been having insomnia, moodiness and attitude swings, leg joint/muscle pain (Restless Leg Syndrome), hot sweats, although no weight gain, have had muscle loss w/girth gain, libido is rock bottom...but, I'm active and try to stay busy. I've had no lethargy, memory loss or fatigue. Found out a year ago my PSA went from 2.5 to 4.8 in less than 15 months. Biopsy came back with 7-8 Gleason numbers across all 8 cross sections taken. Had MRI and bone scan to determine if cancer had spread outside the prostate wall. All were negative. Started first Leuprolide Acetate injection in late October. Received 25 external radiation treatments by mid January. Implanted w/46 radioactive seeds in late Feb. Another injection in March and one again in July. Taking 400mg of Magnesium 1-2 times a day to help with the leg pain...it helps. Taking 10mg of Ambien 15 minutes before bedtime and that REALLY helps to sleep..but it's a struggle to "get going in the morning". PSA taken last month was < .1 which is good news. Seeing the Oncologist in a few weeks to discuss future need for the Lupron. Would like to get off of it ASAP! M 58 10 months
3X O
9/7/2010
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 3  Large Fibroids Felt changes immediately after getting the shot, I could feel less pressure from the fibroids. My period came on time, which i thought it wouldn't and is slightly heavier than normal. Having severe lower abdominal cramps which i've never had before. The cramps are the worst, standing upright or slight twisting movement causes pain. Applying light pressure to my lower abdomen causes pain. I'm taking the shot once for 3 months span to shrink fibroids, to be followed by lap surgery to remove fibroids. F 34 3 months
11.25mg 1X O
9/6/2010
 1  to shrink fibroids for surgery within 48 hours I developed phlebitis and blood clots. I later suffered a Pulmonary Embolism. Other "usual" side effects included hot flashes and mood swings. Most recently my hair started to fall out. It did really shrink the fibroids, but it lasted only 3 months. Now I have to wait even longer to have the hysterectomy because of the Pulmonary Embolism. F 42 1 months
one shot 1X M
9/4/2010
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 4  Fibroids Joint pain, and slightmemory loss. I get a heavy period a few days after each shot. Semi heavy I was scared to try this medicine after I read this site, but I am on my 3rd shot ans have very minor symptoms. Joint pain is probably the worst. I have had one hot flash (so far) and memory loss slightly. I thought that I was going to hate this drug, but so far it has not been as bad as a I thought, I get my next ultrasound in about a week so I will know than if the fibroids shrunk. Oh my hair is falling out but not in clumps, just falling out a lot easier than before. I find it everywhere now. F 32 3 months
1X M
8/29/2010
 1  endometriosis nausa,vomiting,stomach pain,diaherra,anxiety,insomnia,weight loss I have done only 1 injection of lupron 11.22 It lasts in your system for 12 weeks. It has been 10 weeks and I just started to eat again. This has been the worst experience ever. I was sick and I mean sick for this whole time. I ended up in er once being totally dehydrated. I could not eat at all. I was either throwing up or had diaherra. I was put on axiety meds to help also. I lost at total of 15lbs. I am not going to take the 2nd dose. F 32 12 weeks
11.25 1X O
8/29/2010
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 3  Endometriosis I had horrible hot flashes and night sweats. Nausea and headaches.I was tired a lot of the time. I felt that my side pain decreased a little bit but around the time of my menstrual cycle each month, I had pain again. I do think it helped. This is my last month on it so Im a bit nervous to see what happens when I am no longer on it. F 20 6 months
1X M
8/27/2010
 4  stage 4 endometriosis decreased libido, hot flashes, mininal depression I was TERRIFIED to start the Depo Lupron injections after reading the horror stories posted by patients on internet sites. I began the drug, once a month for 6 months. I can honestly say that I am EXTREMELY sensitive to meds, and, I feel great! I have decreased libido, but, my husband is VERY sensitive to the fact that I'm on a medication that is causing this! Hot flashes DO happen, but, NOTHING unbearable. I am on an antidepressant anyway for generalized anxiety, and, I had to increase my dose VERY slightly. As far as the weight gain --- there has been NONE of that for me. As a matter of fact, I may have lost weight slightly. Please take it from me that this med is NOTHING to be scared of! It is worth the 6 months of treatment! F 29 3 months
1X M
8/26/2010
 5  Stage IV endometriosis None I was scared to death to get this injection after hearing nothing but horror stories about this drug. I got the three-month injection from my doctor, so there was no turning back with this if I started having bad side effects. I've had no real side effects so far and it's been 12 weeks since my injection. My doctor did put me on add-back therapy with Premarin and I'm sure that's helped reduce any side effects. It has definitely helped my pain from the endo. I wouldn't say it got rid of it 100%, but it's such a drastic improvement. I'm really glad I got the injection. F 33 3 months
1X O
8/24/2010
 1  endometriosis I went crazy ended up in a mental hospital lost my memory Could'nt walk properly had extreme nightsweats/mares I lost my children gained 60 lbs I had no idea what was happening Please if anyone knows how to get a class action suit going email me at [email protected] F 45 12 months
1X M
8/22/2010
 3  Fibroids, 13 cm, 5cm, numerous smal Into 3rd week, period started with more clots than usual, night and day sweats, tingling and numbness in hands and legs, swelling and soreness of feet, some slight pressure in chest. Third time in 2 1/2 years taking the 3 month injection to stop periods and shrink fibroids. Very little shrinkage of fibroids, stopped period for one month with the first injection, and less bleeding for two months with the second injection. Have had numerous blood transfusions, one time hemoglobin was at 4.2, frightening. Trying to stop period after last transfusion and infusion of iron, so hemoglobin/hematocrit will build over 10.5 in order to have hysterectomy and stop vicious cycle of transfusions, periods, transfusions, periods, etc. F 57 2.5 years
3 month 1X O
8/20/2010
 4  Fibroids Night sweats....in general just hot at night I have been on Lupron about two weeks. And I haven't had any real negative side effects. Well nothing that I thought was ruining my life as one poster said. But I am keeping an eye out to anything out of the ordinary F 33 2 weeks
3 month 1X O
8/17/2010
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 3  Prostate Cancer fatigue, debilitating hot sweats, hot flashes, loss of concentration, depression, liver dysfunction, weight gain (10 lbs), complete lack of libido, moodiness, lack of enthusiasm, blood sugar swings, sleeplessness I am very worried about the drug long term effects. It has been over six months since my last injection and the side effects seem to be getting worse rather than better. I will not continue using the drug. My PSA has been greatly reduced but the doctor cannot tell me if it was from a successful, 40 session radiation regimen or the drug. This lack of knowledge of how the drug works and how long it side effects will last (or the magnitude of the effects) leads me to recommend other options. M 59 9 months
6 month 1X O
8/17/2010
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 3  Prostate Cancer Hot Flashes, Cold flashes, weight gain, fatigue, complete loss of libido, Nausea, Depression, Moodiness, Mental degradation (Not Mentally acute) I had the robotically assisted Laproscopic Prostatechtomy at the end of July 2009, PSA count at 6 weeks out was .55, at 3 months .65, and at 6 months 1.1, so a 8 week course of radiation with Lupron injections was recommended. After 1 month on Lupron the PSA count dropped to Zero, I'm still waiting for the next test, but I cannot stand being on this drug much longer. The moodiness, hot flashes, fatigue, and weight gain are ridiculous. Use this if you must, because it does work, and will extend your life while you work for a cure. But as soon as I can I'm getting of of this stuff. M 52 5 months
1X O
8/12/2010
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 3  11 cm fibroid Was initially scared to take Lupron after reading the side effects. In 3rd week of first shot and it hasnt been too bad. I've lost some weight (about 6-7 pounds) from nasuea/vomiting and get night sweats and have some trouble sleeping through the night. But I can tell that the fibroid has shrank some because there isnt as much pressure on my bladder and kidneys. I got my period about 10 days ago and only bled for 2-3 days but have had constant fluid leakage since then. Possibly from the fibroid shrinking. It definatley hasnt been the nightmare I expected it to be but it hasnt been a joyride either. F 30 3 weeks
3.75 1X M
8/4/2010
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 4  Stage 4 Endometriosis I am 25 and I Have had 4 Laperoscopys and with the last one the doctor told me I had Stage 4 endo. He said this was my last opption in getting preggo before i needed to to invetro. I was Realy nervous about taking lupron after reading all of the side effects. On top of being nervouse my Health insurance didnt pay a penny. It was 2500$ a shot here in the US so i Ordered it from Canada for 800$. My doctor told me that the side effects would be the same as menopause. So i was prepaired for hot flashes, night sweats, and Weight Gain. But the Only Side effects I had were the Hot Flashes and Night sweats. I acctually lost 30lbs by just eating a little healthier than normal. I was already a little over weight and didnt want to gain any more. I love Lupron, I love not Having a Period. It got rid of all my Pain and now im just hoping to get preggo!!! I took 1 Shot every Three months for Six Months F 25 6 months
11.25 2X O
8/2/2010
 1  endometriosis I have been currently diagnosed with endometriosis and was recently given this drug. I freaked out when my stomach went numb as well as my left arm and leg. The doctor couldn't believe the side affect but it has occured. I thought I would try the dose again and see what happens and now I am numb again!!! I will never take this drug again. I would rather have my pain then deal with numbness and tingly sensation in my arm and leg. F 34 2 months
30 mg 1X M
8/2/2010
Email
 1  Endo F 44
11.25 1X day
7/31/2010
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Patient History
 3  Endometriosis HEADACHES, night sweats, severe fatigue, mood swings (but only a few severe so far), achy, less of a sex drive than usual. Some nausea too but I think that's just from the endo. The headaches and fatigue are definitely the worst. I get my 2nd of 6 shots next week. I hope I survive 6 months of this. But it'll be worth it in the end. I'm also taking Aygestin to help with the side effects so I can't imagine what it would be like without it. F 27 1 months
1X M
7/30/2010
 3  endometriosis After having severe pelvic pain and cramping since February of this year, my doctor and I decided to go through with a laparoscopy which I had about 8 days ago, my doctor was able to get most of the endometriosis but not all of it so she suggested Lupron. My aunt is an OB/GYN and suggested that surgery + Lupron is the best way to go. I have an appt tomorrow to start, I have read so much about all the side effects and possible problems with it. Out of everything that I have read nothing says when you start feeling the side effect i.e. 1st day or 1 week later? anybody have any input? I will also post again and let people know how my experience goes. My ultimate goal in this whole process is obvious pain relief but also hopefully I will be able to have kids since I am only 24 yrs old. F 24 6 months
1X M
7/28/2010
 3  Egg Donor I am experiencing spotting and some minor menstrual-like cramps and bloating. I'm not sure if the cramps/spotting are due to Lupron, or to Reclipsen, which is a birth control pill I also have to take. I have noticed spotting consistently for the past 3 months with Reclipsen but the Lupron did seem to make the spotting heavier, almost more like a light period. I do not get migraines normally so I haven't experienced anything like that on this medication. The side effects are a little uncomfortable but I'm still able to go about my day as normal. So far it seems like a tolerable level of mild discomfort to help someone have a baby. I have not noticed anything major and I expected the bloating, which is more of a "feeling" of bloating than anything physically visible. I have a healthy diet and exercise routine generally. I also eat a low sodium diet which I think helps reduce the bloating. I am an otherwise healthy, fertile egg donor taking Lupron to stimulate egg production and coordinate my cycle with a surrogate mother. I rated it a "3" because I'm not taking it for my own medical/fertility reasons, but to help another couple. F 28 5 days
10 Units 1X day
7/27/2010
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