LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  IVF - hormone supression Extreme back pain - upper and lower. Stomach pain, nausea and vomiting. Increased vaginal discharge, raised liver function, dark coloured urine. Very good at supressing hormones, just not sure that the side effects are worth it. Last time, I administered via a nasal spray 4 times daily and this had much reduced side effects. F 36 4 weeks
3/25/2008
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 1  Endo Headache, hot & cold Flash, bone ache , lower back pain, pain at the injection site, hip pain,depression, bulging disc,knees, ankles pain, diagnosed with fibromyalgia in 2007 If I know what I konw now I would never taking Lupron it is a DRUG FROM HELL and I got Pregant on the lupron and it is a Category X and I should never had my baby, I don't think my Dr was aware of all the side effects, It need to be recalled . It is runied young woman's life. When I was giving Lupron in 2002 I didn't find anything bad about Lupron. I will sue them they will pay for what they are doing to people. it is a unsafe DRUG that the TAP and FDA need to recall because thier are more side effects that come with the drug.I will never ever be the same , I would take back my ENDO any day them live life with the side effects from LUPRON. F 30 2 months
3/25/2008
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 5  endo w/ cronic pelvic pain pain, bloating I had surgery in Feb. 07 found lots of endo. Took 2 Lupron shots 1 April 07 other in July 07. So I did not have a period from Feb. 07 until Feb. 08. That was the WONDERFUL part. I hated all the hot flashes. Unfortunately I have to say that in Feb. 08 and March 08 periods were bad to the same chronic pain problems w/ major bloating. While on Lupron I was not bloated at all either. So now tomorrow we go and schedule for a complete hysterectomy. A friend of mine that works at the Drs. office went thru the same thing and after she finished the Lupron shots her symptoms came back as well F 37 6 months
3/23/2008
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 3  Endmetriosis Hot Flashes, Mood Swings, Night Sweats, Severe Joint Pain, Tingling in Arms/Fingers, Nausea, Loss of Appetite, Severe Stomach Pain. I just had my 4th & final shot this January. I knew I was going to experience Mood Swings & Hot Flashes, which were bareable. I started having pain in my knees to the point I couldn't walk up or down my stairs.(I live in a 3rd fl apartment) The pain in my shoulders wakes me up at night.(I'm taking Physical Therapy for my knees & shoulders right now) And for the past few months everytime I eat I get nauseous with severe pain. I chaulked all these other ailments up to being individual things. Figuring they had nothing to do with each other. But after reading these posts I am convinced they have to be connected to my Lupron shots. I'm upset my Dr. never metioned I would have such severe problems. The other thing that worries me is I still haven't gotten my Period. I was told I would get it 6 weeks after my last shot. It's been over 2 months now. I had a pregnancy test done when I was admitted into the ER over a week ago for my severe abdominal pain. So I'm not preggers. The ul F 32 4 months
3/17/2008
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 3  endometriosis headaches, hot flashes -- i am still very early in the process After reading this forum, I had decided not to use this drug. I spoke with a nurses who was experienced in its use and some other doctors whp felt like I should proceed and that side effects are rare. Not to negate anyone's experiences here, but I decided to start a daily journal to give people a daily perspective of what this drug does. I have no idea how it will turn out, obviously. The link is http://lupronjournal.blogspot.com. I wish everyone peace and a successful treatment. F 35 4 days
3/17/2008
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 1  endometriosis The side effects were HORRIBLE! I felt nauseated and fluish - headaches, bodyaches. Then the vomiting started. I ended up in the hospital for 5 day because I could keep no food or liquid down. I continue to battle the severe nausea and occasional vomiting, but some other meds are trying to counteract that. I had the major crying, sweating, paranoia, thinking I was losing my mind. Normally, I'm a really stable person. This was OUT OF CONTROL! F 40 2 months
3/16/2008
 3  STAGE 4 ENDO, FROZEN PELVIS Hello, i had my first shot Feb 12,08. My Dr also prescribeb Aygestin, for me to take once a day. So far I have had night sweats, blured vision, and some leg pain that only lasted a few days. I have not suffered from any headaches, hair loss or dryness. For those who have had so many problems from the drug, ask your doctor about "add back therapy", it may help. F 40 1 months
3/15/2008
 5  Severe Endometriosis Hot flashes, night sweats, irritability - but nothing over the top. Originally, I came here and everyone's comments really scared me to death, but after having surgery to remove cysts and as much endometriosis they could, I still had alot, so after researching both the good and the bad, I went for it, and I am so glad. Sometimes I feel like out of the blue I might self-combust, and yes it might be a little embarrassing when all of a sudden your talking to someone and you turn into a red hot tomato. My BIGGEST worry was about irritabilty and depression since I already struggle a bit with that. But,really,nothing much at all. In fact, I realized about two months in that I hadn't taken ANY pain meds. Usually I was popping those suckers like candy. Because of the bone loss as a side effect, I made sure to take my calcium supplements, and also note that if you can also take "add back" to decrease that side effect. All and all,I'm very glad I took it and am sorry for those that could not benefit. We are all different, and really my positive F 41 6 months
3/12/2008
 4  Fibroids I took my first injection Feb. 21 2008. I started my period Feb. 25 and until this day I am still on my period today being march 10. I am experiencing hot flashy and night sweat. I hoped that the Lupron would help control the bleeding but I seem to be bleeding more than be for. I also have anemia bad so bad that I can not have surgery until my iron level is up. A month ago it was 7 (12). I have times when I feel slightly depressed and do not want to get up. I take my next injection March 22. It has not been so bad I am only 2 1/2 weeks in to this. F 47 18 days
3/10/2008
 1  prep for surgery to shrink uterous Drenching sweat, shaky, irritable, vaginal walls so dry that they were splitting and bleeding. Menopause symptoms which is what it does. TSH levels are affected. I was MISDIAGNOSED. My heavy, long periods, weight gain, and severe cramps, and always being tired and severely dry skin turned out to be HYPOTHYROIDISM. Luckily, the LUPRON shrunk my 3 uterous to the size of a pea and they canceled it. I now have ashermans syndrome. I could not have intercourse for over a year as my vagina was dried out and the Lupron took over a year to leave my system. GET YOUR THYROID checked BEFORE any OBGYN surgery. I had a prior ballon obalation that failed. F 47 30 days
3/6/2008
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 4  Stage IV endometriosis Fatigue, mild joint pain, occasional headaches, increased warmth at night This is my second tour of Lupron in 14 years. My final shot was a week ago. This time I am taking an add back therapy pill which has minimized the hot flashes. I do feel tired and occasional headaches have occurred, but that would happen when I was on oral contraceptives. My case is a little unusual because I am asymptomatic in terms of the endometriosis. A 9 cm endometrioma was discovered 14 years ago as part of my annual exam. I have not been debilitated with pain. The OC's were managing the endometriosis very well(annual imaging proved this), but had a breast cancer scare a few years ago and never went back on them even though I could. Hence they started to grow. My doctor wanted to due surgery I opposed, because I am asymptomatic and fertility is not an issue at this time sought another opinion and agreed to the Lupron. The only surgery I want to have is the final one and I am not ready for that know. The ultrasound a few weeks ago did show some reduction. Continuous OC F 41 6 months
3/4/2008
 1  ENDO AND CYST hot flashes,night sweats,horrible migranes,bone and joint pain,upset stomach(all the time) This drug is exactly what I read about. I took a three month shot a little over a month ago and I feel like a different person...and not in a good way. I was always very active and full of life and besides my pain felt pretty good but this drug has made me the complete opposite. All I can do is lay down because I am so tierd, I have to save all my energy for work and that leaves me none for my family. What is crazy is I have already had to have a full hysto except for my right ovary and my doctor still convinced me this would be better than surgery!!! YEA RIGHT!! As soon as the three months are up I am having my 5th surgery to remove endo and cyst and my right ovary and never taking this drug again. F 26 1 months
3/1/2008
 2  Endo It has been a continuous roller coaster ride. I have been on the shot for 4 months side effects are hot flashes, night sweats, hair loss, excessive skin dryness, acne, abnormal hair growth on face, weight gain which has never been an issue for me and major fatigue and moodiness. Also as if that was not enough I am so dry vaginally that it hurts like the first time every time my husband and I have sex. However with all that said it has helped with my pain from the endo. If I had had all the facts of what Lupron was and does to your body I would have opted for the endo. Don't do it. It has lasting effects on your body F 33 4 months
2/25/2008
 5  Endometriosis Hot flashes, sweats I took the shot at 26 and I am so angry that I went off of it. I took Lupron to stop the bleeding and pain; cramps and depression were severe, prior to Lupron. I was much happier, healthier, and living my life, while on this medication. I lost weight, looked good, my mental state was wonderful. I wasn't depressed due to my period. Now I am going to go back and take the shots again. F 30 6 months
2/21/2008
 5  cysts, endo, pelvic pain A few hot flashes, some sleeplessness, a little moody/ irritable. All very minor and workable. I've had 4 monthly Lupron injections to help decrease the occurence of cysts, possible endometriosis, almost unmanageable cramping during ovulation and menstruation and unexplained pain in my pelvic area. That part of the pain is GONE! For 3 years I've had consistent pain and with the Lupron taking care of the uterine and ovarian pain, I can now deal with issues with my digetstive system. F 47 4 months
2/13/2008
 3  uterine fibroids - pre-myomectomy Hot flashes, depression, anxiety, pain on lower back on spine, triggered the worst period for 12 days causing severe anemia, weird intermittent soreness on upper part of inner/front thighs I'm taking the equivalent of Lupron (trenatone-gyn) which is the same but made by a japanese pharmaceutical company. I was slightly anemic before the treatment but after 3 weeks of treatment I had a mens for 12 days, where I lost a lot of blood and became severely anemic, so the lack of energy must be from the anemia, sleeping 12 hours a day. At times extremely depressed and anxious, I have to take antidepressants after I tried to manage for 2 months without them, but I used to take them 1 year ago. My doctor gave me this because I asked him crying if there was a way to avoid a hysterectomy (I really did not want one eventhought 2 gynecologists told me that my 5 fibroids are a reason for one). I wonder now if there was another alternative to this treatment because it concerns me what is doing to my body and health, also losing bone mass it's probably what is doing to my back but happily I'm very athletic, still lifting weigts at least once a week, swimming a little and running once or F 46 2 months
2/9/2008
 4  Endometriosis No side effects. A few the first week, nothing bad. Feeling so much better. Cut my pain meds from 6 a day to 2 a day. Lost 10lbs in a month. Feel better mentally and physically. More energy and back to running again...I missed that. F 37 2 months
2/6/2008
 1  endometriosis and PCOS severe hot and cold flashes with hives, severe insomnia, servere muscle and bone aches,loss of muscle mass, depression, loss of appetite, weight loss, severe lowered immune system, severe irritability, fatigue, severe memory loss, dizzy spells I would recommend that nobody does this drug. I was on this drug for a year and half. I almost lost my job and lost people who cared about me because I was not myself. Also a lot of people don't understand that it's not helping the endo, it's only masking the systems. I finally got of the drug and when I did the endo was worse than it had ever been. For anyone out there seeking treatment, I found a leading world specialist, Dr. David Redwine, and had surgery. He is absolutely against this drug. Since my surgery 5 months ago, I feel like a completely new person, he removed all the endo!! I still have side effectsf though from the lupron and have been told that this could last for a year or two. I still have not got my bone density back. I would strongly advise against this horrible drug!!! F 28 1.5 years
2/6/2008
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 1  ENDOMETRIOSIS Dec 26, 2007 got 3 months worth shot (LUPRON) ...I am Not sure if it has worked for me YET !!!! Had LAPAROSCOPY Dec 7,2007 Dr. found TERRIBLE case of ENDOMETRIOSIS.Got my period Dec 24,2007. Started Lupron Dec 26, 2007(3 MONTHS worth SHOT) I felt GREAT till Jan 19,2008 were I got my Period for 7 days and still continued spoting after urinating. I Got the horrible burning feeling back AGAIN on both sides of my RIBS, I had the same BURNING feeling before the LAPAROSCOPI. I been having hot flushes and night sweets for a week now. Tomorrow Feb 1,2008 I have an appointment to see if I have something else, because ENDOMETRIOSIS seems to pront PAIN but I have NO PAIN. What feel is this HORRIBLE TERRIBLE BURNING FEELING and I also feel that my stomach is going to explote after eating or drinking even WATER,and burnign doesn't stop. I feel acid reflex. Has anyone felt this? F 33 34 days
1/31/2008
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 1  fibroids Not sure. Numbness and tingling in my arms at night when I try to sleep. I almost bled to death do to fibroids in my uterus. Ob/Gyn wanted to stop my periods until I could have surgery/partial hysterectomy. I got the 3 month shot 2 months ago. I continue to have periods exactly the same (extremely heavy) for 2 months now. Recently I have developed numbness and tingling in both arms, right arm predominatly, whenever I lay down to sleep. I am trying to figure out if it's a side effect of the Lupron. I have had NO symptoms of menopause and it did NOT accomplish what I needed it to. F 45 2 months
1/19/2008

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