LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Endometreosis I got BLOOD CLOTS in my Lungs,(pulmonary embolism) and nearly died. I was taking Lupron with "add-back therapy" progesterone-only BC Pills, which increased my risk of blood clots. No doctor even mentioned the risk, never brought up for discussion. (Lupron's website of course does list this as a risk.) after the fact, my doctor said P-only pill is lower risk than Est-BC pill, but i still got clots on the P-only pill. I(was) very fit and healthy . Apart from the nearly dying of Pulmonary Embolism part, in the 6 months of injections, i had really rotten side-affects. a veritable parade of misery-foot pain that made walking very painful (still with me 4 months after), nausea, nigh† sweats, 20 lb weight gain, sharp intestinal cramps. i can't really say if the lupron helped with Endo pain, since the side affects were similar to my Endo pain. i had Lap Surgery, it went great,i felt good, then i started the Lupron. i regret it. F 44 6 months
7/7/2007
 4  fibroid I'm in my 20's and have been taking lupron for 5 months, I've put on at least 10lbs, I have no mood swings but the memory loss is insane, maybe I just cant remember the mood swings. I cant remember names of people or things that have taken place and I'm usually quite brilliant. confusion, hot flashes, insomnia, falling asleep randomly, slow mental capabilities, high sugar and overall food cravings. Swollen abdomen. The bleeding has reduced to mere spotting, but it is ever so sporadic. Its better that the alternative F 20 5 months
7/5/2007
 4  fibroid I'm in my 20's and have been taking lupron for 5 months, I've put on at least 10lbs, I have no mood swings but the memory loss is insane, maybe I just cant remember the mood swings. I cant remember names of people or things that have taken place and I'm usually quite brilliant. confusion, hot flashes, insomnia, falling asleep randomly, slow mental capabilities, high sugar and overall food cravings. Swollen abdomen. The bleeding has reduced to mere spotting, but it is ever so sporadic. Its better that the alternative F 20 5 months
7/5/2007
 1  Prostate Cancer I think I have them all. Hot flashes, energy loss, aching in back and legs, confusion, irritability, etc. After suffering through Lupron for three long months, I had told my wife that I was considering discontinuing the treatment prescribed for six months while receiving proton radiation therapy. After visiting this site, I have made up my mind. M 48 3 months
7/5/2007
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 4  Fibroids, heavy cycles Hot Flashes, sleeplessness It has been GREAT. I am actually worried about getting off it. It was to shrink the fibroids , so far it actually hasn't done this, but I am not bleeding and feel like I have my life back. I am going for my 7th shot, and another sono to see if there has been an shrinkage onthe fibroid, so that I can be a candidate for Endometrial Ablation, a permanent solution to the bleeding without drugs, and outpatient(can't do it with a fibroid this size). Trying to avoid a Hysterectomy. Side effects have been minimal. I am glad I did not see these postings first. It may have stopped me from getting the shot. F 45 7 months
7/4/2007
 3  endo bone pain, mood swings, hot flashes, night sweats, migraines, and weight gain I just finished 6 months of lupron. It helped with the cramps, back pain, and sciatica I've had to deal with. The first month I hadthe worst bone pain, some nights I hurt so bad I couldn't get comfortable. I've had mood swings- I would go days without talking to anyone, afraid that I would bite heads off. Migraines, hot flashes, night sweats and I must have gained at least 30lbs. I will never take this again! I don't think I could deal with the symptoms again. F 31 6 months
7/4/2007
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 1  Endometriosis memory loss, confusion, joint pain, pelvic pain horrible, horrible drug F 34 6 months
7/1/2007
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 1  During IVF Excessive vaginal hemorrhaging for six days resulting in signif lowering of hemoglobin from 14.4 to 7.0 and lowering of RBC to the point of danderous anemia. Increased irritability mimicing severe PSM. F 53 30 days
6/27/2007
 3  Endometriosis and to shrink fibroid Hot flashes, insomnia, pain in my kidney/liver area with extreme skin sensitivity around my stomache, side and lower back. I don't know yet if Lupron is helping to shrink my fibroid, but I had the injection in the recovery room after having a laproscopy to treat endometriosis. I had a long, heavy period that wasn't more painful than normal, however. I have had one other injection and have started to have mystery pains and skin sensitiviity that my doctor can't seem to explain. There needs to be more patient education and research on this drug. Has anyone else had skin pain? and if so, what did your doctor do for it? F 34 50 days
6/23/2007
 1  Endometriosis Fibroid Cysts Hot Flashes, Psychosis, mood swings, headaches, insomnia and absolutely no relief from pain. Despite it all, I will still need the surgery which I opted for but the doctor insisted on trying lupron. The administered a three month dosage which should Never be given. It is an extremely expensive drung and the doctors reap to benefit from the pharm. companys for pushing. PLEASE don't allow them you give this to you. I have several weeks before the inital dose wears off and hopefully the after effect will be mild. However, everyday feels like an eternity when the depression and psychosis hits. Suiside and horrible recurring thoughts plagued my mind and it's very difficult to fight when you're on an emotional rollercoaster. Just say NO to Lupron. F 31 3 months
6/23/2007
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 2  Endometriosis Weight gain, tiredness, irritability, feel lousy, headaches. I wasn't aware of all these possible side effects. I gained 10 pounds in 1 month. I am so tired all the time. I dont feel like doing anything, and that is hard dealing with 2 small children. Hot flashes!!! F 33 3 days
6/21/2007
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 2  Endometriosis Hot flashes, headaches (these eased after 2nd shot), severe joint pain, mood swings, weight gain, decreased energy level. The first shot took away the pain but left me miserable from the side effects. Now it's nearing the end of my 3rd shot, I'm 10lbs heavier and I have pain again. I know this has worked for other people but I will not consider this medication in the future. It seems to be so hard on the body. F 35 8 months
6/16/2007
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 1  Endo, Chronic Cysts, back & pelvic Weight Gain, Depression, Loss of Libido, Muscle Loss and Pain, Pelvic & Back Pain, Hot Flashes, Hip, Legs and Joint Pain. Loss of Sleep and Night Sweats, Fatigue, Swelling and Water Retention, Break through Bleeding w/Ovarian Cysts. Early signs of Osteoporosis. If you r going to do this, make sure you have a support system, my fiance had to endure ALOT, but he pulled me through! Lupron wasn't for me, I started the shot when is was 18 yrs old, and for the next yr & 1/2 I felt like a 85 yr old woman. I was very healthy and athletic before the shot, days after the side effects started and cont. till 6 months AFTER I was off the shot. I also went through a withdrawl period! I had to start going to physical therapists 3 times a week for pelivc, hip and lower back pain 2mnths after 1st shot. I was diagnosed with PMDD and early signs of osteoporosis. I have been off for 6mnths and have had 2 period, and they where the most painful and debilitating experience ever. I lost one good job because of this, I am doing all I can not to lose another. Dr. wanted to do this to get me off all the narcotic meds, and I had to up them b/c of this. My only question is where do I go from here, I have had surgery, done the shot, done other replacement hormones, I F 21 18 months
6/12/2007
 2  endometriosis HOT FLASHES!! Heavy prolonged period, cramping, irritability, feeling of being angry at times, fatigue, pain in lower back, joint pain in hips, dizziness It has been almost a month since my first injection and within the last week I have began to experience some not so pleasant side effects. I hope that this is just from the initial surge of hormones. I feel angry at myself for agreeing to take this shot and for how Dr.'s seem to disregard the true side effects of this medication. It is a waiting game. I do hope that things improve but for now I am not happy about how I am feeling. If things do get better as far as pain I am not sure that what I am experiencing at the present time is worth it. I may change my mind down the road but for now I am very disappointed with my decision to do this. F 27 30 days
6/11/2007
 4  Endometriosis depression, hot flashes, night sweats, confusion, mood swings, weight retention, vaginal dryness, loss of libido. Con't..... Yes this a DRASTIC change from your norm, but I think the outcome will be good health. It feels like a horrible price to pay (I feel awful daily & struggle to see the glass 1/2 full sometimes), but perhaps in the end we'll be healthier, pain-free, & even able to conceive if we choose. Try to do something positive for yourselves during this time. I encourage all to find a strong support system & seek out a consistent and healthy diet and exercise plan. I started nutrisystem to easily stay in control & turn any hormonal weight gains into maintenance/slow weight loss as well as continuing to exercise 5-7x a week. Chin up! What does not kill us makes us stronger. Love from L.A., Sailor F 37 3.5 months
6/5/2007
 4  Endometriosis depression, hot flashes, night sweats, confusion, mood swings, weight retention, vaginal dryness, loss of libido. I have been on Lupron since February. This is the roughest ride ever on SO many levels! As the menopausal state the drug puts you in is extreme, I would like to advise all to keep in communication w/ your doctor about ALL side effects. My doctor has put me on a low dosage of estrogen to take daily, & I'm now "functioning" like a human being, (though not quite in top form), & many of the physical side effects have subsided. I'm looking forward to the time (hopefully 4 months or less) when I am feeling like myself again. I remind myself daily there is a light at the end of the tunnel. Although the Lupron sentence feels long and unfair, I would like to tell you all the same. I'm lucky to have a great support system. An OB/GYN that truly cares, a great therapist, an empathetic mother, a boyfriend who knows I am not myself & reminds me this is all temporary, & good friends who can't grasp it but listen intently. Yes this a DRASTIC change from your norm, but I t F 37 3.5 months
6/5/2007
 4  Unexplained Infertility/Pre-IVF Over-tired, some slight & random joint pain and headaches. Nothing severe. Taking 10units nightly for 3.5 weeks, now on 5units nightly. F 39 4 weeks
6/3/2007
 1  Endometriosis Muscle/joint pain, total loss of libido, hips hurt all the time this drug should never have been approved!!!! I researched before taking and decided it couldn't hurt, Dr wanted to put off hysterectomy. By second shot didnt want to take third, having joint pain/loss of strength, Dr actually pulled out book showing joint pain not a side affect, talked me into taking third shot. Joints became so painful he gave me mega doses of estrogen to try to counter act Lupron. Had the hysterectomy and its been HEAVEN ever since. (24yrs of debilitating endometriosis pain and multi laps) Its been 2 1/2 years and still cant lay on sides, hips hurt to bad, flair ups when I hobble like an 80 yr old, now getting all these other effects, major mood swings, cant remember anything, very irritable, cant stand to be around people much. No doubt that Lupron caused permanent hip damage, maybe others are early menopause (just turned 40) just want to say, PLEASE PLEASE PLEASE DO NOT RISK TAKING THIS POISON... the small chance it will help is not worth the permanent problems if it doesnt, there are other things to do e F 40 90 days
6/3/2007
 1  severe endometriosis, frozen pelvis MAJOR hot flashes, feeling of weak bones, insomnia, ringing in ears, feeling of being under constnant stress, racing heart beat, weight loss.For me gaining control of my (-)behavior was the positive change. Lupron helped my endometriosis for about 8 months, then it came back again. Exercise, proper diet and losing 30 lbs was the cure. Believe in yourself, listen to what your body is telling you. It might help you. Take care of yourself. F 44 6 months
6/2/2007
 1  prostate cancer hot flashes, loss of libido, weight gain. Men, think very hard before taking this drug. Your doctor will probably tell you (as mine did) that the side-effects are temporary and that you will return to your normal after discontinuance. I had my 4 month lupron depot shot in August. It is now June and the drug is still very active so far as I can tell. If you don't mind being chemically castrated for an indefinite period, then by all means take this drug. If that prospect bothers you however, think very hard before consenting to being injected. There must be alternative equally effective means to the same end without the crippling side-effects. M 58 9 months
5/31/2007

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