LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Endometriosis Hot flashes, Night sweats, severe depression, weight gain (50lbs) I've been off said drug for almost 4 years and I am still suffering from the depression, and the inability to lose the weight. F 23 6 months
6/26/2008
 1  vaginal bleeding severe hot flashes & swets, weakness,fatigue, memory loss,insomnia ( I was waking up every 15 min through the night, felt like i was loosing my mind), irritability, mood swings, crying with no reason, severe dizziness, vaginal dryness, bone and joints pain,weight gain 30lb It was not worth it. Long lasting side effects. I did not see the benefits. My life was turned into a living hell. Now about one year after the treatment I still feel very tired and lifeless. I continue to gain weight. If I would have known about all these side effects I would not have taken it. I don't recommended it to anyone. I strongly believe this drug should be pulled out of the market. I hope somebody will take legal action against those who produce such a poison. I was in college during the treatment and I had to drop classes because I was extremely sick. Pure nightemare!!! F 38 3 months
6/23/2008
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 3  post op endometriosis acne, mood swings, joint pain, depression, hot flashes, headaches, fatigue, light headiness I've only had my first shot so far and ive already felt a lot of the side effects but theyre all pretty much bearabe. i only hope that they don't worsen or get extremely bad until i finish my 6 month treatment. I wouldnt reccomend this drug unless u REALLY need it and is a last option. F 22 1 months
6/21/2008
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 4  Submucosal Fibroids Hot flashes, mood swings, mild acne, night sweats, slight weight gain, joint pain/discomfort, headache, vaginal dryness and lethargy (probably due in part to not sleeping through the night) I was on Lupron 37.5, month-to-month shots, as a way to manage heavy bleeding (hence anemia) prior to a hysterectomy (May 15, 2008). The injections shrunk my fibroids and my uterus (to 57 grams or about 2 ounces) making it easy to surgically remove abdominally. Generally, I am pleased with the drug's performance, but it definitely was difficult to manage the side effects at times (the hot flashes and lethargy, especially). Although my last injection was almost 8 weeks ago, I am still experiencing some of the side-effects, and my doctor is at a loss as to when I can roughly expect my ovaries to begin functioning normally again because the Lurpron has worked its way out of my system. F 32 5 months
6/20/2008
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 4  endo hot flashes, insomnia, headaches, bloating, weight gain, very tired I was diagnosed and had lapro sx and removal of right ovary in June '07. Waited until October to start Lupron (wanted to wait until after my wedding and thank goodness I did). I started taking Lexapro 10mg right before my first injection. I experienced terrible migrain-like headaches and exhaustion immediately post injection. After a month those symptoms were less frequent. I also took Ambien p.r.n. when I needed help sleeping, which was about twice a week duirng first 3 mo of therapy. I started having hot flashes almost every day. I believe the Lexapro helped the moodiness and menopause symptoms. After 2nd injection, I felt better, but was contantly hungry (am, pm, late -night)and always felt bloated and had acid reflux when I ate. Gained 15lbs during those last 2 mos of therapy. I was exhausted and had zero desire to workout. Finished therapy in April. Started LoEstrin24 in May have had two periods with minimal cramping and pain. Trying to lose some weight and find my energy F 31 6 months
6/16/2008
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 3  Ovarian Cyst ( 4.9x6.4) Extreme fatigue for first week following each injection, Occasional hot flashes and night sweats,insomnia, hip and lower back pain. Abdominal bloating. I was very anxious prior to starting Lupron therapy. I could'nt find very much research on it's use for Ovarian Cysts. In the first month there was little to no change but I did still get a period and had almost constant pelvic pain like i was having period cramps all month. F 27 2 months
6/16/2008
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 5  Fibroids Hot Flashes, minor mood swings, insominia, minor joint pain. I started taking Lupron in January 08. I have had 3 shots now and I feel great. Yes, I do get the hot flashes and I do have some minor mood swings and a little bit of joint pain. In all it is worth it for me. I had a blood transfusion in December and one in January from bleeding from the fibroids. I am very thankful that my doctor that I have currently gave me the option of Lupron. My fibroids have gotten smaller and I am getting a hysterectomy in August. I occasionally have some minor spoting and after my first shot I bled like crazy for 2 weeks then it just went away. I would do it again if I had too. F 37 6 months
6/13/2008
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 3  Endometriosis Hot flashes, unusual tiredness, vaginal irritation, headaches more frequently, bleeding (like a period sorta) I have been on this shot about 2 weeks. The only side effect I have had that is painful is the vaginal irritation. I also have Vulvodynia and Fibromyalgia. My dr suggested it as an alternative to a Hysterectomy. I was just diagnosed with Endo in April 08. Doc sd had Endo for a few years but wonder how come never diag. F 33 14 days
6/13/2008
 3  fibroids and endo extreme night sweats, hot flashes, nausea, numbness in arms and hands, fogged thinking I had the lupron shots for 3 months to shrink fibroid tumor. It did not work the tumor is still huge. I haven't had a shot in 6 weeks and the side effects seem to be worse the last 2 weeks. I have surgery scheduled july 1 for a myoectomy. The night sweats are the worst. F 38 3 months
6/12/2008
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 5  Large fibroids Hot flashes, slight weight gain I wish I could stay on the medication longer because it was wonderful to not have a period. Was expecting the worst but fortunately my side effects were manageable. My weight went up 8 lbs but I was able to continue working out and felt more energy physically and my mental capacity seemed to improve. My mood has also improved. Overall, I am happy I made the decision to take this medication, it was the best choice for me. F 41 6 months
6/8/2008
 3  Shrink fibroid tumors Hot flashes at least every hour, night sweats, moodiness and joint pain in my knees. Don't know yet if my fibroid tumors have shrunk. F 41 2 months
6/5/2008
 3  Andenmyosis Forgetfulness,Hotflashes,night sweats,cold flashes, anxiety, extreme tiredness, right after reciveing shots very emotional, headaches, loss of energy, loss of sexual pleasure and lower libido Unfortunaly this is a drug that for women like me who suffer from something that cannot be 100% diagnosed even with Laproscopic surgery have to try. I feel like a lab rat at this point and the next stop for me is hysterectomy. So facing that I will gladly take this path first. The shot in itself is not bad it is the hormone surges that are bad. I am currently tkain premprin to help with the most annoying side effects however it dosne't work for loss of energy, tiredness, or lower lowered libido. I would reccomend it to anyone who needs to have their periods stopped for medical reasons. F 31 1 months
6/5/2008
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 1  endometriosis, fibroids In the beginning side effects were hot flashes, headaches, diarreha, abdominal pain, muscle pain ,most of this was mild and I thought it was related to the endo pain. Over time I developed Fibromyalgia, Chronic Fatigue, Insomnia, NAFLD, digestive problems, daily headaches. It has been 7 years since my first injection and I still suffer daily. I recently had a hysterectomy and still have pain. I know it was the Lupron because prior to it I only had endometriosis and fibroids. Also once my periods resumed after treatment I began to bleed for 17 days a month. Check out lupronexposed.com website it is very informative. I stumbled across it in my quest to try to figure out what the heck was wrong with me and why I felt so sick all the time. I was shocked to read so many women are experiencing the same long term side effects as I and the only common thread is that we took Lupron. It can't be a coincidence!!! Do your research and homework before you take this drug. F 35 6 months
6/5/2008
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 5  endomitriosis I was diagnosed with endomitriosis at 18. I had been taking bc pills to keep the pain and blood down. I was spotting badly and so we decided to try lupron to calm things down. So far I have had almost no side affects other than some minor bouts of deppression. No heat, pain, fatigue and no periods. I would definitely suggest the taking-back or whatever they call it with the estrogen. I feel better than I did taking the birth control. While this may not be for everyone, I see no reason for giving it a try. You never know until you try. F 20 2 months
6/3/2008
 5  Prostate Cancer in order of discomfort: sleep disorder, memory loss, fatigue, extended belly, hot flashes, no lipido, did I say memory loss? After radical and chemo my PSA went from 20 to 83 in 4 months. After my first three month Lupron shot it went to .0001 and stayed there. I am not cured but my life has been extended. Ten accupuncture treatments cured my hot flashes. Pray for a cure for all the prostate cancer survivors! M 57 3 years
5/31/2008
 4  endometriosis acne, slight mood swings, hot flashes I was very scared to take lupron after reading the comments on this website. I am so glad i made the decision to take it. The only reason i did not give it a rating of 5 is that I have one more shot to go to make a total of 4. I have not felt this good in over a year...and I hardly had any pain with the endo. I have so much energy and have been hitting the gym 3-4 times a week and have lost 10 pounds. I will have my final shot in 1 week and will then go on clomid to induce ovulation...hopefully I will get pregnant. I have never been the kind of person to write a review but I just had to let people know that for me it was totally the right decision. While searching the web, more often than not I found negative comments and reviews, I want people to know that some of us are doing great and having positive experiences!!! F 32 3 months
5/30/2008
 5  Fibroids I've only had the shot for 10 days and immediately experienced hot flashes and headaches. I had minor abdominal pain, but other than that, I feel fine. I'm more tired than normal and felt like I had flu symptoms the other day, but no complaints. I think this is going to work for me. I'm scheduled to have surgery in August so I can be done with all this discomfort. At first, I wasn't looking forward to it, but seeing that I have my children and grandchildren, I don't plan on traveling down the road of reproduction. I'm glad my OB suggested this and wish I knew about it earler. F 42 10 days
5/27/2008
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 1  ENDOMETRIOSIS Mild hot flashes, severe mood swings, joint pain, back pain, anxiety, night sweats, abdominal distention, weight gain, nightmares. I took lupron for 6 months for enometriosis that was more prominent on my left side than my right. I gained 25lbs on the shot the majority of it stomacch weight, and am having a really hard time getting the lbs off. Shot not worth it, still in pretty bad pain...add back therapy helped a little. I still have problems, cysts. I have been off for a month and a half and am still waiting for my period. I would rather live with the endo on pain killers - not much alternative. F 22 6 months
5/22/2008
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 2  3 Ovarian Cysts, 1 Fibroid At first night sweats, hot flashes. One month into it, insomnia, memory, fatigue, acne, chest tightness and headaches. Initially, only night sweats and hot flashes. As time went on, the third week, two cysts ruptured and had to go to the hospital after 5 days of horrible pain. (see ovarian cysts rupture sypmtoms) I had them all. My belief is, this drug caused them to rupture versus "shrink". I'm in total suppression and now experiencing headaches, insomnia, memory/difficulty with concentration/focus/mild acne, chest tightness and some depression (no doubt from feeling like a big hot sweaty mess) ; ) F 39 1 months
5/21/2008
 2  3 LARGE Fibroids/Endo and Cyst Serious Hot Flashes//Horrible Joint pain (especially in my knees) and my arm is always tingly and falls asleep at night. I have been on Lupron for a few months now. I have 3 very large fibroids inside and outside of my uterus. I have a large cyst on my left ovary, and a large amount of endo. My first shot of Luporon wasn't so bad, although I did get a lot of hot flashes. The next time, I go the 3 month dose. Oh boy...I am putiing up with this b/c I really don't have a choice...The hot flashes come and go very often...and is very anoying! But the joint pain is killing me...it hurst so bad each time I walk up the stairs, bend down to reach something...just in general...my knees always hurt! I was pretty active before being on Lupron, and my joints never were a problem. Also, the doctor said that I need to loose a some weight before having surgery, but with one of the side effects of the drug is weight gain...it makes it all that more difficult. It is just very fustrating. I am staying on it as long as the Dr. says I need to be, but it wish there was another way. It makes me feel a lot older than F 30 3 months
5/5/2008
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