LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1   Extreme fatigue, severe headaches, memory loss, leg pain, severe acne everywhere even on the tops of my hands and fingers. Do not take this med it ruined my life. It did not help my endometriosis at all. It got worse and I ended up having a total hysterectomy 2 years later. Wish I had the hysterectomy 6 years before, would have save a lot of pain and loss of life due to spending so much time in bed or on the couch. F 49 6 months
3.75 mg 1X M
1/22/2011
 3  Endometriosis I had some issues with mood swings, hot flashes only during the first 2 months, weight gain (10lbs), fatigue. I'm always hungry so I don't know if it was the shot or just me using the shot as an excuse to eat. My symptoms were managable. I went to work everyday and did well on the shot for 6 months. No periodds or spotting for 6 months. It was nice. I received 6 months of Lupron (1 shot per month). As I stated, I did fine. However, around 28 days after receiving my last Lupron shot, I got my period. And it was horrible. It was heavy and back to being painful. My doctors could not understand how I got my period so soon. They said that most women don't have periods for 4-5 months after the last shot. But, I guess everyone is different. So it really did help for 6 months but then it was over and back to period reality. I went on Lybrel but continuously spot on it. It's been 8 months since my last shot and I am going in for a laproscopic again. This will be my second surgery (the first being almost 10 years ago). I take Ibuprofin 800 when I feel the cramping coming on and it has helped so much. F 33 6 months
3.75 1X M
1/20/2011
Email
 3  endometriosis The first week after I was given the shot was horrible. I barely got out of bed that week due to horrible headaches and overwhelming fatigue. I gained 5 pounds in the beginning of being on lupron, then all of the sudden I lost my desire for food at all, just the thought of eating will make me sick to my stomach. Random crying and flipping out on my family over nothing,I can't control my emotions at all anymore. uncomfortable hot flashes, but they are pretty manageable. The pain from the endo has gone down a little, but im only on second shot, my doctor put me on add back therapy to try to help the symptoms but so far no such luck. I extremely worried that me going on this medicine so young will effect my chances of having kids later on in life. F 19 6 months
1X M
1/18/2011
 3  Fibroids- heavy bleeding and pain Night sweats, hot flashes, more emotional than usual, sleeplessness. After receiving my first shot I was horrified to read some of the claims that Lupron is an "evil" drug that will surely ruin your life. While I sympathize with those who have experienced extreme and negative side effects, I don't think these situations represent the norm. For me, the benefits outweigh the risks- and so far so good. Apart from the inconvenience of hot flashes and being more sad than usual, I believe that this drug is helping to shrink my fibroids and it's gotten me off the morphine I was needing to get out of bed each day. My tummy is visibally smaller from shrinkage and the bleeding has all but stopped. Please discuss all concerns with your doctor before taking Lupron, but do not dismiss it as a treatment option based on negative ratings alone. Best of luck to everyone. F 36 1 months
7.5mg 1X M
1/17/2011
 1  Endometriosis; chronic pelvic pain On a good note, it did reduce my pelvic pain moderately. My bowel movements and pain with urination and intercourse were also moderately reduced. Negatively: the absolute worst thing was the crazy mood swings. I don't mean a little more sad or happy at times - I mean standing in my husband's face and yelling my head off while at the SAME time knowing I was yelling over absolutely nothing; becoming physically hostile towards others, totally out of character. I began sinking into a depression over this. Caused MUCH marital strain. A few years ago I had been on 80mg of Prednisone for 10 months straight, which was absolutely terrible - yet being on Lupron eclipsed the side effects of Pred and was much, much worse. I also now have a condition called Lichen Sclerosis, which is a permanent skin disorder of my genitals due to the hormone disturbance on Lupron. I also had many hot flashes and night sweats, but this is an obvious and fairly common side effect of menopause at any age. PLEAS I received one injection of a 3-month dose of Lupron. Total effects lasted about 6 months, which was when my periods returned and the majority of my mental/mood effects faded. F 32 3 months
1X O
1/17/2011
 4  fibroid 9cm - heavy periods hot flashes, very mild night sweats, mood swings, dry skin around my eyes, initial weight gain of 5 to 10 pounds but by my 3rd month almost back to initial weight After reading the comments on this site I was very nervous about the injections. After the first injection I noticed an increase in bloating and weight around my tummy - 5 pounds. I also noticed slight hot flashes but nothing crazy. 2nd injection...more hot flashes,...up 2 to 3 tmes per night for a glass of water and waiting to settle. 3rd injection - my doctor told me I wouldn’t experience anything more but he’s wrong. I have hot flashes 7 to 8 times a day and night. BUT...I really have to say its nothing that can’t be handled..My surgery is in 2 weeks and I didn’t have any of the scary side effects that are mentioned here. I keep busy with pilates and working out whenever I can and eating a healthy vegan menu with a glass of wine now and then...good luck to all. I think its worth it. F 49 3 months
375 1X M
1/7/2011
 3  Gender Identity Disorder Increase in libido, spontaneous erections, stronger erections, increase in hunger, HOT FLASHES My psychiatrist recommended lupron to stop my puberty progressing while i decide whether to take female hormones, but so far ive actually had an increase in testosterone levels. Theyre supposed to go up for about 2 weeks after the 1st injection but its already been three weeks, and im not sure whats happening with them. M 17 1 months
3.75 mg 1X M
1/7/2011
 5  Fibroid 18cm Bone pain, some night sweats I was prescribed this drug to reduce the size of my fibroid(s) before a myomectomy. After reading the comments posted on this site I was very scared of taking Lupron and even considered not taking it. I decided to go ahead as I had no other real option and I am so glad I made that decision. Whilst I have had some side effects such as bone pain and night sweats they have not been extreme or debilitating and haven't affected my day to day life. The fibroid has shrunk considerably and all the associated discomfort has gone. I am about to have my 3rd injection and my operation is scheduled for 3 weeks time. I would tell anyone faced with the option of taking Lupron to make the decision based on your own situation, everyone is different and you cannot predict how your body will react but Lupron can be an effective treatment. It definitely worked for me. F 40 3 months
3.75 mg 1X M
1/6/2011
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 2  Endometriosis Exhaustion, swollen breasts, migrains, hot flashes, slight memory loss, depression, anxiety, nausea Prior to taking Lupron I wasn't feeling great either. It seemed like I was feeling a little worse so I searched for Lupron side effects and found this site. It explains so much. I've had a full hysterectomy. I have severe endometriosis still and was hoping to stop any endo remaining with Lupron. I believe now most of my pain must be related to adhesions as my pelvic pain is not going away. I was really frigtened to take Lupron so I only took the 1 month shot. The side effects so far are very uncomfortable but I can still function and as I mentioned I wasn't feeling good prior to taking Lupron so I wasn't sure if how I feel now was Lupron related or prior pain related. I believe now that much of the side effects I have are Lupron related. I'm taking imitrex for migrains, tums for nausea, and pain pills for pain as well as prozac for depression. Although I don't think Lupron is helping and the side effects are not great, I can still function, a fear I had after my initial reading of side effects. So if you plan on trying Lupron, the side effects are real, but with a 1 month shot I can still work. I want to put this in the reviews because that was one of my biggest fears ... that I would be in bed 24/7. F 43 15 days
1X M
1/4/2011
 3  Fibroids/Heavy Bleeding I got one shot 7.15.2010 and had one long heavy period exactly 1 week later 7.22.2010. I have extremely severe hot flashes and all-day sweating-sweat literally drips off me. The shot was supposed to be given every 3 mosnths but I declined all additional shots. I have had no period since the week of 7.22.2010; the doctor has no idea when it might start again. As far as she is concerned "mission accomplished". As far as I'm concerned new doctor is in order as the fibroids and bleeding were 2/3 of the problem; pain during intercourse still occurs. F 42 6 months
11.25 1x3m 1X O
12/28/2010
Email
 2  endometriosis I dont feel any unusual symptoms except for my normal symptoms of endometriosis but I am concerned because I just started bleeding today. I thought this drug is supposed to stop your period. Im not sure if its my period because my period has been jacked up the last three months. Im on this drug because the doctor is trying to avoid doing another lapo since my endometriosis returned within a year. I have already had my gall bladder taken out, c-section, and lapo and he says that its not good to continually do surgery so right now Im scared because I'm facing a hysterectomy. Ill be 30 in June and I have a 7-year-old I just dont want to have to decide the rest of my life right now. F 29 2 weeks
1X M
12/20/2010
Email
 4  Fibroids Migraine and couple of hot flashes, but let's say I already had those before... Everytime I get the injection, I get sore a bit around it but that's it ;) I am 37 and taking this drug because of my anemia...so much bleeding I couldn't leave the house for 5 days. I had breakthrough bleeding and was driving me nuts. But now I barely have anything. I did have a period the first month and really bad but I never have pain while I have them. I workout 3 times a week and really take care of myself. My life is general is very good. I have 2 fibroids 9 cm size I hope the shrink and gives me a break for a while. I might try for a second child or have my uterus remove, will see. Good luck. F 37 2 months
3.75 mg 1X day
12/16/2010
Email

Patient History
 4  To shrink fybroid tumors my side effects little dizziness, night sweats then cold, insomnia and getting up at night to go to the Bathroom, mood swings and great deal of sadness. But Doctor did a ultra sound and they are shrinking ,my surgery is scheduled December 27th so looking forward to the hystorectomy and getting my life back to normal. iam so happy to have done this. Iam so happy to have done the shot. F 51 3 months
30mg 1X M
12/9/2010
 4  Stage 4 Endometreosis Hot Flashes, moodiness, slight depression, slight weight gain So far so good, Im on a one year course and so far I have not had any more painful periods, no bleeding, and no cramping! I am still having painful sex, but hopeing that goes away in a few months. Doctor says that if this does not help my endo, I will become infertile from how bad it was before. I know that the hotflashes I had came about 4 times a hour!! It was horrible, but I got on 5mg of progesterone once a day, and now I have been hot flash free!! I suggest everyone to take this!! I know the weight gain sucks and it will probably get worse before I am done with my regime, but it will be worth it to be able to have a family of my own someday!! F 25 3 months
3.75mg 1X M
12/8/2010
 3  endometriosis Joint pain, sleepiness, headaches, a little bit of nausea. I was very scared about getting depression, as I have suffered from it in the past. Fortunately, I have not had that as a side effect. (at least, so far). I was VERY scared to start Lupron because of the possibility of depression. I actually started a blog to track my side effects and kind of keep a journal about this whole process. I hope it can help other decide if they want to go through it or not. The address is: www.mylupronjourney.wordpress.com I hope it can help! Good luck. F 27 3 weeks
1X O
11/30/2010
 2  endomitriosis Hair loss, weight gain, depression, night sweats, joint and bone pain, acne, insomnia, dizziness at times, extreme fatigue, and headaches. I tried to deny that all of this was side effects of Lupron for quite sometime. I came back and read the side effects again and could not deny it anymore. It seems the depression has gotten worse. Not sure if I would go through this if I had the chance again. I get one shot every 3 months and am considering not taking the next one. M 35 2 months
1X M
11/28/2010
Email
 5  14.5cm Fibroid I am now going on my second week since I have had the shot. So far so good. I have woke up in the middle of the night sweating, but that's about it. After reading this site, I was pretty scared about the shot, however I haven't felt this good in over a year. Before the shot I thought I was going to bleed to death, my sevre cramping... crying all the time, and just miserable. The bloating and the bleeding have slowed down. I still have a couple of months on this shot, so I pray the side affects that have been described stay away. F 34 3 months
not sure 3X O
11/26/2010
 3  Fibroids Minor hot flashes, some weight gain, mood swings, horrible headaches (same headache for about a week this time) I am taking Lupron to prepare for a myomectomy to remove large fibroids in about 2 weeks. The hope is that it will shrink my fiboids and also stop my periods to increase my hemoglobin. However, I still got my period last month and it was worse than usual-using an entire box of ultra absorbancy tampons/overnight pads in 4 days. The most annoying side effects are the mood swings and headaches. I haven't had problems with the headaches until the past 2 weeks or so, but I usually have a migraine-strength headache for at least a portion of each day. The mood swings have also been stressful--I'll go from being fine to being in a 'rage' to feeling depressed to fine again. I am hoping that the Lupron worked to shrink the friboids and to improve my blood count and that the headaches and mood swings go away SOON! F 25 1.5 months
1X O
11/24/2010
 1  Endometriosis Dizziness, Headaches, Severe Insomnia, Horrific Hot Flashes/ Night Sweats, Hair Loss, Mood Swings, Memory Loss, Joint and Bone Pain, and Extreme Fatigue! (I have horrible pain from my endo but would rather deal with that then the side effects of lupron!( I have had two separate six month series of the Lupron shot and know both sides of this drug. The first time I experienced some mood swings and mild hot flashes. Nothing to be concerned about. Now a year later my new Dr. told me I needed to take it again. I had horrific side effects this time and wish I would have never taken this horrible drug!!! My endometriosis is very bad, I have had two laprascopic surgeries and wish I would have just gone that route again! The shot didnt help with my endo pain either time, I still have severe pain during intercourse (NO FUN!!!), horrible cramping during my period, heavy menstrual bleeding, and unexplained pains during the month! This drug did nothing for me and I urge you to do plenty of research before you try it! If you decided to go through with it I wish you only the best of luck! I think the only thing that has gotten me through this is my wonderful husband. We are hoping to get pregnant when he returns home from over seas. (He is a soldier) We tried for a year to get pregnant before he left after my second surgery and first round of lupron with no luck. I hope to one day find a way to deal with the devastating symptoms of endometriosis but I do not believe Lupron is the way!!!! F 23 6 months
11.25 1X O
11/20/2010
 1  Endo Lupron has changed my quality of life. I have had chest/heart pains since receiving 3 months of shots for endometreosis. The shot was sent to my Drs office I never received list of possible side effects from Lupron until I called and asked them for the info. Lupron sent me through menopause, joint pain, headaches, depression, exhaustion. Now I am a 34 year old woman with constant chest/heart pain and exhaustion. Shame on Lupron!! My Dr acted like the Lupron shot was no big deal. I wish I would have had info on Lupron. I wish I had a choice. Please investigate this drug before using it. I would have opted for hysterectomy F 34 4 months
1X M
11/19/2010

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