LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  to treat endometriosis heat flashes and chronic insomnia that was so bad I went three whole days without any sleep. I developed arm and leg twitches and went into seizures and was hospitalized. I would not recommend this drug to anyone. I still can't sleep well after almost a year since my first injection. I have restless legs and I feel the drug has aged my face ten years. F 44 6 months
12/11/2006
 4  endometriosis Hot Flashes, SEVERE Migraines, Gained 15+ pounds in 3 months, Bladder weakness, breast tenderness, SEVERE abdominal cramping, unable to have sex because of cramps After my last shot on Aug 1st, I still haven't gotten my peiod yet. I had severe, at times debilitating migraines and cramps. When I wasn't having a full-blown migraine my head was *literally* in a constant state of throbbing or gnawing pain. My head did not stop hurting for 3 and a half straight months. It got to the poing that I didn't even realize it anymore, I just thought that's how I was now. It sucked. The cramps would come on suddenly like someone stabbed me with a knife and I would double over unable to move. I had a ton of hot flashes. Even with going to the gym and only eating slightly more because of an increated appetite, I gained over 15 pounds in under 3 months. I still haven't been able to lose the weight. However, I think the endo is mostly gone, as I'm not having pains anymore but I don't have my period back yet either. I had surgery for endometriosis when I was 22 and it came back again (I've been on the pill even before surgery) so Lupron seemed like F 25 3 months
12/10/2006
 1  Endometriosis Headaches,HOT FLASHES, severe decrease in sex drive, acne, weight gain (and I do not gain weight easily), extreme mood swings, depression I took Lupron for 6 months and would rather have been dead than taking this medicine. I was unbearable with my mood swings, I felt very depresed and could not stand to be around myself. The hot flashes were very severe. I would have them constantly all day and all night. I have been off of Lupron for almost two months and the hot flashes have not subsided at all. My mood swings have gotten better and my sex drive is slowly improving. My pain did not improve during the course of the medication. I had a laperoscopy done before treatment and immediately afterwards and still produced endometriosis tissues. I am 24 years old and facing a total hysterectomy, and thought lupron was my last chance at saving my uterus, but it failed. F 24 6 months
11/30/2006
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 1  Fibroids Loopiness and dizziness I posted in May 06 about my experience and have to say that after being off Lupron for a year now, I still have effects. I have many days during the month in which I feel "loopy". I have a sense of dizziness and as if I'm not balanced. I am able to function but I am definitely not the same. Did I need Lupron? I don't think so. I had the surgery. Lupron was to stop the periods before. Knowing what I know now, I would have had the surgery sooner, without the use of Lupron. F 41 4 months
11/29/2006
 1  prostate cancer alternating cold shivering with intense hot flashes every 30 minutes. loss of energy, depression, weight gain, anxiety, dulling of fine motor skills. The medical community needs to take another hard look at this very dangerous drug. I was told it was the best way to restrict the spreading of cancer cells from the prostate to other parts of the body. I was not told of the intensity and debilitating side effects, some of which could become permanent. I will not take another monthly dose unless I am convinced that my cancer will spredand and become incurable. M 69 2 months
11/28/2006
 4  endomitriosis hot flashes, night sweats, weight gain, and mood swings. I was first told that I had endo when i was 15. I had the surgery and it worked for about 3 years. Now I am in the Marine Corps and can not be slowed down by the pain that i was having. I took the Lupron shot hoping that it would work so i could be back to normal and contine my training. The first 2 weeks were absolut hell! I still had serve cramps when my period was supposed to be on for the first month. After the first month, however, I have had nothing. PAIN FREE ALL THE TIME! I am waiting for my period to come back on now. So I can see how well it really did work! And even though I am done with the shot, I still have hot flashes from time to time, but nothing else. F 19 3 months
11/27/2006
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 5  endometriosis I HAVE HAD NO BAD EXEPERIENCES THE ONLY THING I HAVE NOTICED WAS I WAS MOODY AND MAYBE A LITTLE GRUMPIER THAN USUAL BUT THAT IS REALLY THE ONLY THING I HAVE NOTICED SO SO FAR SO GOOD IT HAS HELPED ME FEEL BETTER I JUST GOT MY SECOND INJECTION SHOT SO TOTAL I WILL HAVE BEEN ON LUPRON FOR A YEAR. F 34 6 months
11/3/2006
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 4  infertility leg cramps F 34 14 days
11/3/2006
 1  Endometriosis Severe hot flashes, weight gain only in the belly, severe anxiety ( I already had some issues with depression & this made it worse) No sex drive, Vaginal dryness, continued pain, Trouble sleeeping due to the hot flashes, Some bone loss. I had my doubts about starting this med. I should have stuck to my gun and not done it. The pain was better for a short time but its not worth all the side effects. I am now going to a specialist to figure out another plan of action. More than likely will be surgery. F 24 6 months
10/28/2006
 3  endo, fibroids, cysts hot flashes, headache, backache mid level (small of back), night sweats, tingling right arm, indigestion-started day after 2nd shot, fatigue, mood swings-irritable and finally no intimacy. This is my last attempt at a solution before surgery. I have very painful intercourse (that manifested right after my marriage)along with heavy and painful cycles. I am not sure if this shot is working outside of the numerous side effects that I am experiencing. My husband says that he will gladly take a loving wife and no sex instead of who I am now------- I do not see it happening! I had my usual cycle on the 1st shot but it was not nearly as heavy or painful. I will only stay on this shot for 3 months due to the side effects. But, I am praying that this works so that I will not have to have surgery. Oh, itimitacy was not painful but..........libido. dang, need I say more? F 43 2 months
10/12/2006
 1  Perimenipausal symptoms fibromyalgia, short term memory loss, sleep disorder, fatigue, depression symptoms, I gained 30 pounds after the 2 injections I received, diminished sex drive, increase in asthma symptoms, weakness in extremities I was glad to here of similar cases with symptoms several years after taking this “medication”. I received 2 injections in 2001 and am still suffering. Now I am on partial disability and the insurance company will not accept it as a "real" disabiltiy. If anyone knows of a class action suit or at least a support group, let me know F 52 1 months
10/12/2006
 5  fibroids Weight gain (20 pounds and counting in 3 months), forgetfullness, bone/joint pain. And the hot flashes!! Decreased interest in sex, irritable This medication saved my life, I was severely anemic and this was the only thing short of a hysterectomy that stopped the bleeding. My fibroid shrank by over half and I'm feeling so much better now! FYI, my MD said she wouldn't recommend more than 3 mo due to the increased side effects and risk of osteoporosis. F 33 3 months
10/9/2006
 1  Endometriosis Stage IV Mood swings, anxiety, depression, insomnia, zero sex drive, facial hair growth, broke out in blisters on my arms...(which of course the doctor said was not-related)... never had them before or since using Lupron. I would NEVER EVER EVER take this drug again. After numerous surgeries and different hormonal "therapy", my doctor recommended Lupron. It was the absolute worst experience ever. It did nothing to assist in the pain/problems associated with endo and left me a basket case. I spent a year doing electrolysis to remove the facial hair. I was up most of the night with sweats and anxiety and crying. It was awful, and I caution anyone who is considering this drug to re-evaluate their options. F 36 1 days
10/3/2006
 3  severe endometriosis hot flashes, yeast infections, some mood swings, skin sores F 15 4 months
9/14/2006
 1  Estrogen suppression after BC hot flashes, abdominal weight gain which i've never experienced before (always been a petite person), weakness, dizziness, mood swings, memory loss, nausea, hyper-sensitivity to smells, sounds, and lights, 0 sex drive, bone and muscle pain, even though I work out regularly. I am receiving lupron to suppress my ovaries so that I may take Arimidex instead of Tamoxifen. Personally, I would prefer to have my ovaries out but my Doctors always talk me out of it. In 2 months I will stop the injections to see if I am in menopause on my own. If not, I will definitely never take it again. I hate Lupron, but I am more scared of a cancer recurrence. F 45 2 years
9/13/2006
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 1  Endometriosis, Edenomyosis 1st 3month shot - Bleeding, slight mood swings. Some joint pain. 2nd 3 month shot - shaking, depression, severe anxiety, extreme bone pain. Hair falling out in clumps, acne. PLEASE, don't take this drug. I should have known better. I did my research and like an idiot thought it would not happen to me. I was not told the full possibe risk of this drug from my gyno. All I got from him was night sweats and hot flashes and that I should take extra calcium. Here I sit totally dibilitated. Thank god my primary care Dr. is trying to get me thru this the best he can with some medications to conteract what is happening, since I am only one month into to the 2nd 3 month shot. There is no way to get this out of your system, you have to wait for it to wear off... My Gyno could care less.. F 42 4 months
9/12/2006
 3  endomitriosis Hot flashes, night sweats, severe mood swings, depression, vaginal dryness, lowering of my voice I'm not having period cramps because, hey-no periods, but I seem to get "phantom cramps" at the time I would normally menstrate. I started this therepy because I was told it was my only chance for ever being able to have children, but sometimes I wonder if rug-ratsare worth all of this. I was briefly suicidal at the beging of my treatment and severely depressed. For these symptoms THERE IS add-back therapy and it has helped a ton with my mood swings and even with my libidl and vaginal dryness. I still get moody and it has put a lot of tension into my relationship with my fiance. If he were any less understanding the wedding would have been called off a month ago.I'm hoping, especially after reading all the negative comments listed here, that the medication will deliver what was promised: being able to walk down the beach without cringing in pain and, hopefully, a family. F 21 2 months
8/29/2006
 3  endometriosis weight gain, extreme hot flashes, itchy skin, moodiness This is my third time on lupron. The first time worked like a charm; it was heaven to be pain and period free. My period took a long time to come back with the same vengance. The second time it was ok; but the endo came back quickly. This time i have been on the drug for three months and want to take a break. It is wonderful not having the terrible and debilitating endo pain, but the hot flashes are excrutiating and the moodiness and weight gain very unpleasant! I know there is a trade-off here, but I do think that Lupron is better suited for younger women. I have also been diagnosed with Fibromyalgia; I have always wondered if the symptoms worsened - or were even caused by - the lupron. But, since hysterectomies also present problems, we all need to stay as informed as possible and make our choices that we feel comfortable with. I think at this point i am done with the lupron, but the first time really helped. Everyone is different! F 42 3 months
8/27/2006
 1  von willebrand's disease weight loss, severe fatigue, seizures, thyroid problems. This drug should be pulled from the market. Tap pharmaceuticals is the ostrich burying their heads in the sand and ignoring the after effects of this poison. I am hoping someone somewhere is able to get a class action suit going against this company. F 16 1 years
8/27/2006
 5  severe endometriosis Swollen breasts and lower abdominal pain in the first couple of weeks. Since I got the second 3 month shot, I have been having hot flashes, joint pain, nausea, weight gain. Had to go to the ER one time for severe shoulder pain My periods were so painful that I couldn't do anything and my prescription pain med wasn't working anymore. I had a lap that confirmed my doc's suspicions. didn't have a choice but to take the medication. F 29 5 months
8/17/2006

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