DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2474 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  For use by females of reproductive potential to prevent pregnancy. Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is also used with or after other treatments (such as radiation, surgery).   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  FDA Adverse Event Summary

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control Weight Gain,Depression, Mood Swings I STARTED TO TAKE DEPO BECAUSEE I WAS STARTING COLLEGE AND DID NOT WANT TO GET PREGNANT. FOUR YEARS LATER I GAINED 30 POUNDS. I DONT ENJOY SEX AS MUCH AS I USE TO. I DONT GET WET LIKE BEFORE. IT IS DISGUSTING. I AM LUCKY THAT MY BOYFRIEND UNDERSTANDS OR ELSE I WOULD PROBABLY BE ALONE. I WANT TO HAVE CHILDREN SO I HOPE THAT WHEN I START TO TRY I AM ABLE TO. TO ALL THOSE WHO DONT HAVE SIDE EFFECTS NOW......... JUST THE THOUGHT ALONE OF SUFFERING WITH WHAT WE HAVE BEEN THROUGH SHOULD TURN YOU OFF FROM THIS PRODUCT. I WISH WE COULD SUE BECAUSE DEPO ALMOST DESTROYED MY LIFE F 25 4 years
5/5/2008
 1  contraceptive irregular bleeding, EXTREME PAIN during intercourse, vaginal dryness, migraines, insomnia, panic attacks, slight weight gain I've only been on this medication for 6 months and cannot wait until it's gone from my body. I wish I never took this stuff. Sex started out as being just uncomfortable as I couldn't become lubricated and was extremely dry... then that problem went away, except sex has become SO extremely painful for me. My vagina feels like it has open wounds and is ripping apart during sex, I've been to the doctor numerous times and they can't find anything wrong with me. Now I know it's Depo, and after reading all these reviews I can attribute my awful migraines that I've been getting everyday, random panic attacks, and insomnia... ALL to Depo. STAY AWAY FROM THIS MEDICATION. It should be taken off the market. Please email me if you want to talk about this more or have any questions. F 21 6 months
4/28/2008
 3  pregnancy prevention loss of sex drive;breast tenderness; weight gain (from 130 to 165);cyst-like weaps in vaginal area; unbalanced Ph (sweaty underarms and vaginal area; alot of water retention in legs and feet;mood changes; headaches; weak/painful joints This is a great product but is definitely not designed for the long term! stop it all together. I was due to recieve another injection in February but i decided to stop getting them.I was taking birth control pills prior to getting the shot because i was having problems with ovarian cysts. My doctor suggested that since i began having problems with the pill that i try depo. He did warn me about the risk of loss of bone density and i knew that i didn't have strong bones, so i took a risk. I was willing to work around the other changes that my body was experiencing but the weight gain has gotten out of control along with the decreased sex drive. It has truly caused a problem within my marriage which is not cool.I was relieved to see the postings on this site because im not alone. Alot of women are or have been experiencing the same side effects as i am. I thought that the changes i was going through were due to age but i see that is not the case. My recommendation to anyone F 29 14 months
4/26/2008
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 1  Birth Control Extreme fatigue, loss of sex drive, irritablity, mood swings. I have been on this for at least six years and every year I went to the doctor complaining that I was ALWAYS tired. I got checked for everything you can think of and yet nothing. I was clueless to the fact that the shot could be doing this but after reading all these other comments I realized im not crazy. I only wish that my doctor suggested this...I went to three different doctors and non of them said it was due to the shot. How clueless are doctors? My shot is up in May and I really feel like getting off of this will change my life completely. I really hate being tired and irritable. People eating chips drives me crazy!! I would recommend not taking the shot, I feel like it ruined 5 years of my life. I never want to do anything, I always want to take a nap and I don’t care to have sex. Low sex drive can ruin relationships. F 22 6 years
4/25/2008
 2  Endometriosis/Birthcontrol 50+ lbs of weight gain!!! Moodiness, irritability, cramps, fatigue. I am a VERY active person. I have played college field hockey at a divison 1 level, so the work outs and dieting are very strict and hard. While I was on depo for two years during this process, I lost no weight at all, in fact I gain 50+ lbs. I have been off of depo for over 5 months and am having a very difficult time losing the weight. The doctor informed me that I may gain some weight, thinking 5 or ten pounds, but not 50+. Do NOT take this drug, not only has the weight gain affected me tremendously, but since being off of it my periods are VERY painful and my body is still suffering from other side effects of the drug. F 21 2 years
4/21/2008
 1  Birth controll, stop periods Extreme mood swings! weight gain to the max in a little time, deppression, loss of sex drive and periods all the time... blotting never ends! It sounded great at first the no periods thing but it does not styop your periods at all for everyone! only certain people stop bleeding! i blotted heavily everyday for 3months! especially during sex it got heavier which obviousley in its own way puts you off sex... then there is the moods and deppression i nearly lost the love of my life because of this! i was never happy and always took every little thing out on him! even though i knew i was doing it i tried to stop and keep my moods and deppression in but you just cant it all comes out of you and ruins everything! i put on a stone in 3 weeks! cant get rid of it either!! I would say to anyone thinking of using the depo injection... DONT it will ruin your life!!! F 19 12 weeks
4/21/2008
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 1  Birth Control weight gain,headaches,increase appettie, depression, manic rages, joint pain, night sweats,triedness, hair loss,just to name a few i would advise people not to take this drug it is destructive to the human body anything that alters your hormones an change up your body like that do is good this drug should be taken off the market and the makers sued this ruin my relationship an my boyfriend left me we had a wonderful relationship before i started taking it an three months after i started everything went hay wire F 32 9 days
4/19/2008
 3  birth control/ period control weight changes, scalp hair loss, acne, periods completely eliminated! I've been on depo twice. My first time was from 17-19 y/o, the second was 21. the firs time I took it, I lost weight and periods stopped immediately. this last time I took it I was on it for six months, and in that time I gained 20lbs, lost hair, broke out like never before. I don't understand, it was great the firs time around... but it's different for every body... what can I say? I loved it AND hated it. I used to have extremely heavy periods lasting more than 10 days before I took depo for the first time... and believe me, it was such a relief to finally be rid of it! so if thats a major concern for you, I'd suggest that you at least try it for a few months... just stay active, you may gain a lot of weight in a short amount of time... F 21 2.5 years
4/16/2008
 3  Birth Control weight gain (40lbs.) mood swings, leg cramps I started this after my first child and I had my period for about 2 months! Then I never went back for my follow up shot. Three years later I decided to try it again and I loved it! No periods, no pills, and it even improved sex drive. Now Im trying to get pregnant again and I am experiencing some things I cant explain. I dont know if its because im off the shot or something else. I dont have insurnce anymore so I cant talk to a doctor about it. F 25 3 years
4/13/2008
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 4  birth control slight weight gain, headaches, moodiness when time for inj. This was wonderful even with the side effects until I reached my thirties. My natural hormones changed and I became dependant on the injections to keep my energy and moods together. When it was time for my shot EVERYONE knew it. I would recommend for temporary birth control but no more than five years. F 37 15 years
4/10/2008
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 3  birth control severe mood swings, no period, inability to lose weight, no energy, inability to get pregnant for 5 years after taking it I loved it when I started it 9 years ago. Then I couldn't get pregnant after I got married. Now, I have 2 children, I'm back on it, was put on antidepressants, I work out but can't lose weight. F 25 1 years
4/10/2008
 1  Prevent Pregnancy loss of sex drive, excruciatingly painful intercourse, mood swings, mild hair loss, mild acne, weight gain now that I am coming off the Depo I am experiencing major cramps like I have never felt before F 25 1 years
4/9/2008
 4  prevent baby making weight gain...oh wait I quit playing sports and didnt change my diet. I mean come on people... alot of problems are coming from your daily lifestyle...tired and loss of drive-probably work, school...you are just tired from life...just quit taking the pill if it is so bad. And never blame a doctor because he/she didnt give you enough information, you let them give you the shot Funny thing that I see everyone complaining about this drug...I thought I had all the side effects but after some blood work i found that I had Graves Disease, weight gain, hot flashes, weird thoughts, feeling nervous, dizziness, eye problems...all from Graves (thyroid problems). We have thyroid problems in the family so my doctor said that it is hard to tell if depo or family history caused the problem...I wouldnt be to quick to judge depo for all problems...it may just bring some other underlying problem out. F 21 3 years
4/8/2008
 1  part of "Essure" perm BC Constant depression with mood swings ranging from violent anger to imobilizing saddness and crying. Since about 30 days in I have been spotting constantly, cramping nearly every day. In combination with this and the fact I have been very antisocial, my sex life went from flourishing to NON-existant. I've gained about two dress sizes because of the combination of not-eating due to neasua and binge-eating for comfort food. I've developed a bad gas problem and have broken out in acne all over, including occational cyct-like welps in my private area. I've even had mild dizzy spells. I have insomnia at night, but the first thing I do when I get home every day is nap because I'm so tired. DON'T DO IT! No amount of over-the counter or holistic treatment eases this. I would never have to begin with but it's a contractual part of the Essure procedure of permanant BC. I WOULDN'T WISH THIS ON MY WORST ENEMY!!! F 29 74 days
4/7/2008
 3  birth control, weight gain weight gain, depression, acne, no period. I actually was prescribed the pill due to my low weight. I have medical problems that cause extreme weight loss. This shot fixed that- I definitely gained weight very fast. However, my doctor did not warn me of other side effects, the worst being acne for me. There was some depression, but I don't know if that was due to the pill or other medical news I received around the same time. But I definitely gained a lot of weight and my face is covered in acne that I can't seem to get rid of. On the plus side, no periods- and my bleeding had been terrible on both seasonique and apri (apri completely cleared my skin of acne as a plus, though). F 26 3 months
4/6/2008
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 1  Birth Control, Severe Cramps I received my first shot 4 days before Christmas 2007. For the first 2 weeks, I was fine. Then I started having stomach problems - it felt like someone was squeezing my stomach as hard as they could. That transitioned into cramps, 3 weeks of spotting, *severe* anxiety and panic attacks (I've been on an anti-depressant with great results for 3 years, and my doctor had to double it recently just so I could function on a daily basis), heart palpitations, gas, 20lb. weight loss, and absolutely no energy or drive to do anything, and hair loss. Some of my friends have loved this, but any medication that relies on a huge shot of hormones into your body can't be good. I didn't receive my second shot, but almost a month after I was due, I'm still experiencing horrible side effects on a daily basis. F 24 1 times
4/3/2008
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 1  birth control I had one shot about 4 months ago... Since then I have suffered from insomnia, extreme depression leading to self mutilation, hot and cold flashes, anger, lack of concentration, development of allerigies (I did not have any before), amoung other things. I am getting my master's and this has pretty much ruined my life. Now I have to see a detox specialist and am seeing a therapist for depression (that was never there before). There are no outside influences that could have caused all this, and although ti was a relief to find out that I wasn't going crazy, now I have to deal with the consequences... DO NOT TAKE THIS (if you like your life the way it is now) F 26 1 days
4/2/2008
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 5  Birth Control Some weight gain, but not positive if it is related to the shot. No Period after 6 months on the shot but that's a plus for me. Slight headaches here and there. It had no effect on my sexual drive or my bone density. LOVE this drug. I would recommend it to anyone. However I do think that each person reacts differently to the shot. I would much rather suffer through a few headaches and some extra pounds than have a child to take care of for the rest of my life. F 23 5.5 years
4/1/2008
 3  Birth Control Weigh gain, loss of sex drive, fatigue, mood swings, night sweats I was on depo for 2 years. At first, I'm LOVING IT, no periods.... awesome. Then over about 6 mo to 1 year, 30lb weight gain. Even tho I'm more active than I've ever been and have never had weight issues before. No matter what I eat or do, weight keeps creeping up!! Doc recommended I go off it for a bit and I doubt I'll go back on. Having been off it for almost 4 mo. I feel a bit of sex drive again. Thank god I have a patient and loving husband. Have dropped a few pounds. Anyway, I tried giving it the benefit of the doubt, but I do believe that the aforementioned symptoms were caused by the shot. I'm not convinced that it is necessarily evil, but also, not very convinced it is the best thing for you. I definitely had a lot of odd things going on with my body that seem to be subsiding, now that I am no longer taking the shots. I'm on the pill and will probably stay there. Plus there is the bone density loss thing. Not good. F 43 2 years
4/1/2008
 1  For birth control After the first day of getting the shot I had horrible migraines the first month. They some what subsided but still got one at least every week or so and I never got them before. I had absolutely no energy and my muscles ached all the time. I also have extreme anxiety and tension that will not go away. Note- I have never had these symptoms before! I would like to see this shot off the market, it does more harm than good! F 21 3 months
3/27/2008

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