DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  irregular bleeding bleeding for 6 months straight every single day, extreme depression and mood swings,loss of sex drive, weight gain (15 pounds), fatigue, dizziness, heart palpatations, headaches,vision problems,this is just a few of the side effects! I orginally started birth control at age 15 due to irregular periods. After Yaz gave me extreme migraines, they switched me to a lower estrogen pill which brought be back to two periods a month. My doctor suggessted Depo and said it would cause my periods to STOP so I thought that sounded great and agreed. She didn't inform me that it could also have the REVERSE affect. I have been bleeding non-stop for over 6 months now and have thousands of dollars in medical bills from fainting and MRIs because I've been so dizzy and fatigued all the time. The mood swings are harming my relationships and affecting my work and school work. Complete loss of sex drive, COMPLETE! A new OBGYN informed me that 30% of women experience reverse side effects...I THINK 30% is ENOUGH TO WARN SOMEONE ABOUT BEFORE TAKING IT! There is nothing you can do to help the side effects except wait it out. I've been waiting 3 months, and no change. I am so unhappy with Depo and strongly encourage everyone to do research before taking it. DO NOT TAKE DEPO. It has ruined 6 months of my life and has messed up my body in so many ways. I was completely healthy before taking Depo. I would rather have 2 periods a month again than be bleeding everyday. The mood swings are unbearable. Slight acne has appeared, too. I'd do anything to reverse these side effects. WE SHOULD GET DEPO BANNED!!!!! All of this doesn't even begin to describe what it has done to me. F 19 6 months
11/16/2009
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 1  Birth Control Method / Avoid pregna Well I wanted to get on birth control and decided to talk to my doctor and I talked to my doctor and asked her what was her decision on the best alternative for birth control and she said depo provera so without doing research first I just went on ahead and decided to go along with what my doctor said because i thought she knew what she was talking about because she was s doctor. And so then she gave me the first dose around may 09 and ii took it and i was due in for my second shot around august 09 and i never did take the second dose thou because i noticed on and off weird periods, spotting, nausea, heavy heavy cramping which i am still getting almost every day now and also no period, and weight gain, I just bought like two or three brand new pair of jeans and now i can't fit any of them because of my weight and also it's been 3 months since i had a period. because before taking the medication i had regular periods then after taking the shot i had very little periods or spotting and t F 23 3 months
11/16/2009
 1  Birth Control Mood Swings, Depression, Anxiety, Stomach and Back Pains. Before starting Depo, my periods were like clock work. After starting Depo i didnt have a period at all. Then I decided to not take it again because all the horror stories i heard about it. Now i have a horrible period every two weeks. Im emotional. I have developed horrible anxiety and hate to leave the house. And have become depressed. I have horrible stomach and back pains. I always feel nauseous, like im going to throw up. Im always exhausted and all i do is sleep. The only side effects the doctor said i would have was weight gain. I only took it once and i feel for people who took it for years. This drug is awful and should not be given as a birth control. F 18 1 times
11/15/2009
 1  Birth control ACNE! Dislike this form of birth control, I have never broke out in my life and ever since I got the shot in October of 08, I've had non stop acne, last shot was March 19th 09 and I still have not had a period and I still am breaking out BAD. I feel like this shot has ruined my face. I'm so unhappy in life right now because of what it did. Other than that it is okay. The bad thing it can stay in your system up to 15 mths, so don't take if you are thinking about getting pregnant in the near future. F 19 6 months
11/14/2009
 3  Birth control Decreased appetite, mood swings, Bloatedness F 19 9 months
11/10/2009
 2  birth control Weight gain, no sex drive, and no feeling during sex. I need some help and this is the most useful forum I've seen. I put on some weight when I started it, but not too much. What's disturbing me more is that after my last shot I really started to feel different; before this last shot I had a lowered sex drive, but now I have really no sex drive and I have vitually no sensitivity or feeling during sex. I talked to my doctor and she said the side effects from it vary, but couldn't give me diffinitive answers. I'm happy that it's so effective in preventing conception, but I'm worried that all my sensitivity has disappeared. Is this normal and will it come back? F 26 9 months
11/9/2009
 1  to not get pregnant since being on the depo i have been spotting and bleeding for nearly five months ,i`ve also had bad back pain no sex drive and been depressed i was fine before taking this . i seriously do not recommend the depo injection to anybody i think it should be banned F 32 5 months
11/9/2009
 1  Bith Control I actually lost weight..too much if you ask me. I lost 60 lbs. Most would say that was great however I was only 158 lbs when I started taking the shot. I was 18 years old. Sore breasts is an understatement. Now almost 10 years later, I still have no children. Talk about your sterility. At first it seemed like a great invention to not have the monthly curse. When you are 18, "sowing wild oats" it seems like a God send..now after going thru all that I have to get pregnant, Depo seems to have been a HUGE mistake. I took the shot for about 2 years and didnt have a period for an additonal 2 1/2 years after I stopped taking it. F 28 2 years
11/9/2009
 3  Dr. recommended. 75lb. weight gain, mood swings, depression, lack of sex drive, achy joints and muscles, severe headaches, lack of appitite, loss of interest in almost everything. My Doc suggested Depo, when I was 24, since I had been having terrible periods for over 10years. It was GREAT!!!! NO MORE PERIODS! No pain, mood swings, living around a period.... Until I started to knowtice continuing weight gain. I even got a personal trainer. I gained even more (approx 15lbs.) Oh something else, Did you know there's some kind of steriod in the shot?! Then I started with the achne... No matter what I've tried it only works for a little bit. The headaches.... I kept putting them down to stress at work, home, school. They're constant! The sex drive... GONE! The depression... well it's constant. About a year and a half ago I went off the shot because I got tired of going to get a shot in the butt every 3months (I'm terrified of needles), it took almost 9 months for my period to come back. And when it did, in some ways it was WORSE than before. For someone who had always been regular (like a clock), everything was all over the place. Months in between, the clots, pain, EVERYTHING! And the more it came the worse it got. Eventually I went back on it. But it's not the answer! I just wish my own Doc, would listen and get to the bottom of my problems and find a way to fix it. Oh I did loose some of the weight when I went off the shot, but since going on it again, I've gained it all back. In some ways yes it did help, but in the ways that matter most... NOT A CHANCE!!!! My recommendation.... IF YOU DON'T HAVE TO, DON'T DO IT!!!!!!!!!!!! RESEARCH, RESEARCH! F 30 6 years
11/8/2009
 2  Endometriosis, Blood Pressure, B/C Severe Mood swings, Low Sex Drive, Irregular bleeding Due to a diagnosis of both endometriosis and high blood pressure, my doctor decided Depo would be my best option for not only treating the endometriosis, but also for birth control. In the two years that I have taken the shot, the only consistancy from the treatment was the inconsistancy. My weight fluxuated, my mood swings effected everyone one of my relationships, and the bleeding became a gamble: Will I bleed today or not? Not to mention the severe abdominal cramps. I have skipped my last shot, and hoping some of these symptoms will go away... No not take this shot. The risks FAR outweigh the advantages. F 34 2 years
11/8/2009
 4  Birth Control Started taking in 06 for birth control. I had been warned of weight gain but noticed nothing but muscle cramps in my calves the week after each shot. Then I took a 6 month break from Depo in 2009. NOT a good idea. I took another shot after the break and the symptoms started..... When the symptoms started, I gained about 15lbs in two months. I have extreme fatigue, I found out my foot is broken (took a physical) - probably from the loss of calcium. I have night sweats, no sex drive, severe depression, hair loss above my ears and crown of head, and my body odor is different and stronger. I will probably not take the shot again as I want to have kids someday and this medicine scares me... F 26 3 years
11/4/2009
 1  birth control DON'T TAKE THIS DRUG!!!!!!DON'T BELIEVE DRUG MANUFACTURERS!!! BAD DRUG!!!!! bipolar, loss of libido, hormonal imbalance, panic attacks, period yet to return, blood clot.... (could have killed me.) F 33 4 years
11/4/2009
 1  Birth Control Mood swings, weight gain, no period. I only took this drug once. it has been 8 months and I still havent get my period.. Do Not Take this drug. F 22 3 months
11/3/2009
 1  Convenience I was told that Depo would stop my periods and that I may have SOME SPOTTING in the first 2 weeks. Not true. I have been bleeding for 6 weeks and have been told this is a normal side effect of Depo. My hair is thinning and falling out and my legs ache all the time. I won't be getting my next shot; I'll go back on the pill F 23 6 weeks
11/3/2009
 1  Birth Control Gained 50 pounds, acne like you would not believe, depression/sad mood Don't take it. A friend recommended it to me, and I regretted it. I took 3 shots before I figured out the shots were causing my issues. It took 9 mo for my cycle to start again, and I have struggled with the weight ever since (got last injection in 2004) by losing it all only to gain it back again, repeatedly. F 34 3 times
10/31/2009
 3  Birth Control- Easier than the Pill Periods stopped, aching joints, no sex drive, increased appetite, dry vagina, soreness in the breasts I've been taking Depo for almost 2 years, because I would forget to take my pills, and the shot sounded much nicer. It was great not to have periods at first, but now it just feels wrong. It's like I'm not really a woman anymore... Like most people here who have taken the drug, I've got a monster appetite, but I haven't gained more than a few pounds so yay! I say it's alright, but I kinda miss my sex drive, and not having achy joints all the time. F 19 1 years
10/30/2009
 2  Birth control Weight loss and minor issues I will cover in comments. Very negative change in vaginal discharge and bleeding: thicker, drier, and everything started to turn brown or black! I came off of Depo in January ('09). It never did what it was supposed to because after taking it I spotted (sometimes bled) almost every day and any discharge was brown or black and tacky. After about 2 months off Depo I noticed a definite change. Improved consistency and wetness of discharge, and my sex drive improved. I have never been regular and though my periods have always been super heavy, I never experienced anything else. But since starting (and stopping) Depo, I have experienced small headaches on a regular basis, cramping (sometimes severe) and I bloat and/or experience gas pain almost daily. F 20 9 months
10/29/2009
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 1  Easier than taking tablets Irregular bleeding and spotting, loss of libido, bad mood swings, depression, didnt want to go out Please dont anyone ever take this horrible drug. It has ruined my relationship due to the terrible mood swings and depression, i wasnt warned of any of this and didnt understand what was going on with my mind and body, saw doc 3 months ago, came off it and had copper non-hormonal coil fitted but can take up to 6 months for effects to leave your body so had to go back on anti-depressants to get me over the worst of the depression F 35 2 years
10/29/2009
 3  to not get pregnant mood swings, mild weight gain, massive hair loss, headaches, backaches, month long periods, extreme fatigue, always hungry, aching hips and legs, feeling soreness in my body as if im 70 yrs old, loss of sex drive It absolutely blows my mind that I was never informed about all of these changes. I tried to ignore them thinking it was just my body changing but thanks to this website I now know it it eventually happens to everyone! I've been taking this shot wayy to long almost 3 years an will not get my next shot. The only good reviews on this site about this shot are people who just started taking it and they will eventually find out that its not as great as it seems to be in the beginning! F 21 3 years
10/28/2009
 1  To stop vertigo (please read on..) Severe depression, psychotic episodes, nausea, heavy bleeding, hair loss, 4 stone gained, joint pain and weakness, messed up my hormones triggering underactive thyroid. PLEASE DO NOT TAKE THIS DRUG. If I could go back over my 40 yrs on this earth and change one thing only, it would be to have never, ever, have started this evil drug. It has ruined my life - the 4 years taking it and the last 5 years since I stopped it. I have done enough research to know that it's this injection that has has caused my problems. I was the perfect picture of health, apart from vertigo, when my Gynaecologist decided that the vertigo was due to a hormone imbalance. As it turned out I had MS. This is now so much worse than it was all those years ago and I now have the effects of this drug to deal with too. F 40 4 years
10/28/2009

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