DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  B/C & No kids Before DP, I was already irregular. After depo, no period like many others. Had migranes which I thought were due to stress. All over body aches which I thought were from lack of exercise&stress. Lower back pains thought to be from epideral. Increased sex drive, increased appetite/sugar cravings. Before depo, 120llbs. Now, 9 years later, 160llbs; thought this was due to having 2 kids and not exercising. People say your body changes every 5 years. Now, I am 30. I have loved Depo up until this year. Now, around the "time of the month", I have been experiencing severe depression and acne I just can not get rid of. I have been on calcium, women's 1 a day, and green tea pills (curbs appetite and sugar cravings, increased energy with natural caffine), blueberry (antioxidant which helps with depression)protein shakes, high-protein diet, exercise, and I have lost 7 lbs in 1 month. I thought losing weight on Depo was impossible! Herbalist recommended SAM-E for depression. I am working on the acne cure still. Depo is not for everyone and after visiting this website, thinking about a bone density test. F 30 9 years
7/2/2007
 1  Birth Control Gained 15 lbs, Swollen Feet and Hands, Hair Loss, Crying Spells, Ab-Normal Moods (up one moment and sad the next), loss of energy. I am a very active person and eat healthy. I box 2 days a week, run at the track 3-4 days a week, work full time, own a all natural bath and body products biz and am a mother of a 9 year old son. So I should not have any reason to gain this much weight in 5 months (cloths do not fit) or to become depressed, I’m also a naturally positive, active and happy person. This shot should not be called Depo Provera it should be Called DEVIL Depo! This has got to be taken off of the market. There are too many uses for it and it was never fully approved by the Government. This is the same drug they give to repetitive convicted sex offenders...this is the same drugs the "experts" say "there are many uses for Depo Provera". I would strongly suggest that women NOT use this as a form of birth control. My doctor warned me, but I am so open minded that I had to learn for myself, and I thinks it’s one of the worst choices I’ve ever made for my health. Never again! F 26 5 months
7/2/2007
 1  BIRTH CONTROL COMPLETE LOSS OF LIBIDO!! weight gain. apprx 5lbs. mood swings. depression, headaches. BOO TO DEPO wow, i recently got off of taking depo. 2 months later, still feeling the effects, but getting better. i can't wait til i feel myself again! i couldn't figure out why i felt this way about sex, and then i started doing some online research and i found out that many women had these same side effects! vtw, it's made my relationship rocky but luckily my boyfriend is understanding...when i talked to my doctor about it, they said they had never heard of these kind of side effects (loss of interest in sex) they did say that women report having a dryer vagina because it lowers estrogen, and they recommended switching to an estrogen bc instead. i can't believe after reading all of these women's comments that no one is doing anything about it. wow. F 22 6 months
6/30/2007
 1  Unbearable cramps. WEIGHT GAIN I don't know of any other side-affects other than weight gain, but that was enough to do it. First of all, the male gynecologist I went to (at age 13, so I elected not to have my mom in the room) said that I had a choice: I could have a period every month, or I could have one never. I was 13. I was dealing with cramps bad enough to keep me bedridden all day and still have to hold my breath to get any relief at all. And he tells me I can have a period never again. What 13-year-old wouldn't choose that? That doctor ended up giving me the Depo shot without my mom knowing, and having mislead me about the side-affects. My mom was furious. And what's worse, he said that the one of the side-affects was, "possible increased appetite." That's COMPLETELY different from the 30 pounds I gained the first summer and the total 65 pounds I gained before I went off of the medication a year later. 65 pounds. I'm the only 17-year-old I know who has worse stretch marks than a woman who' F 17 1 years
6/29/2007
 5  breast pain and tenderness no period, lower sex drive, possible loss of bone density I started depo for birth control while breastfeeding and happily discovered that it relieved me of the nearly constant breast pain that I had had for 3 weeks of every month since my early 20's. They used to hurt whether or not I was on birth control. I seem to be the only person on this site with this situation. I have been very happy with depo, but I am going to stop soon to protect my bones. I do worry that my breasts will hurt again like before. I don't know if my periods will return as I now have hot flashes and have started menopause. Depo seems not to have affected my weight nearly as much as my exercise and diet do--my weight has varied by 12 lbs. up or down in 9 years. F 42 9 years
6/27/2007
 4  birth control bone-joint aches severe fatigue nervousness no weight gain, but I cant loose my pregnancy wieght I have only had one shot so far, and I wasn't informed by my dr at all. But after looking up side effects I realize that the pain that I have been feeling in my bones and joints which worsens after a short walk is due to the shot, also lately I have been experiencing severe fatigue, like 12 to 14 hours of sleep whenever possible. F 23 2.5 months
6/25/2007
 5  birth control brief spotting, annoying at first, but it never returned i've had very little problems with the shot since i've taken it. i've gained weight, but i've had problems with that way before i started taking it. i can't say that i'd recommend it to anyone because not everything is suitable for everyone. i didn't have any problems before taking it and my body's adjusted to it since. not everyone's body will be right for it...and all side effects aren't necissarilly caused by the shot, some people might've had previous problems to begin with. so far, it's only benefitted me. F 17 3 months
6/23/2007
 1  Birth Control An inability to be objective, Severe and passionate mood swings that are retrospectively embarrassing, No period the 1st year, Bleeding only after orgasm the 2nd year (that was a fun answer to field from my newly-unvirginized boyfriend), Acne, and Extreme depression. The change of weight that everyone experiences on this drug has everything to do with how depression effects your appetite...I went from 120lbs to 160 (that's 6 dress sizes and 2 bra cups - maybe I should add back pain?). I found this website out of curiosity, because the period of time I spent on Depo-Provera was a memorable one. It was 4 years ago, and I took the injections for 2 years. I have a motto for Depo: "please, no." Okay, I just came up with that. But I do discourage anyone considering or taking it to look for another option. I chose Depo-Provera for birth control because I had never taken daily medication in my life, I'm a little absent-minded, and I planned on having lots of sex in my first long-term relationship. I went on the pill once I realized that my hormones were whack. It was difficult to recognize in my state, which is why I want other women to read this. After a few months off of Depo, I started to see things more obectively. I lost weight, I wasn't as depressed, and when I looked back at my actions through the entire period, I was a little shocked by my behavior. After 5 years of manipulating my hormones and, I have to say that I highly recommend rubbe F 25 2 years
6/22/2007
 4  So i don't become Pregnant they are very little or none some times... The biggest thing was becoming use to not having a period regularly... F 18 1 years
6/20/2007
 1  Birth Control Depression, Anxiety, Nervousness, mental confusion, loss of libido, overall feeling of hopelessness I was a perfectly healthy person before starting on depo. Now I wake up every morning with anxiety and nervousness. The only time I feel good (I think) is when I am sleeping. The med has interfered with my everyday life. I can't concentrate and I can't shake this feeling of hopelessness. Definitely not continuing on this med, no more artificial hormones for me!! Doctor attributes my anxiety level to my four kids, but I wasn't like this with three kids and I felt great before starting this. F 28 9 months
6/20/2007
 1  Missed Menstrual cycle low body fat Horrific - depression, terrible headaches, hair loss, stroke like symptom, early menopause symptoms, clotting, loss of mental acuity - this stuff is POISON & should be illegal. It ended my career, my relationships & took away my sense of self. POISON - Don't take it - The effects have been permanent - over 10 years! F 51 1 days
6/18/2007
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 3  Decrease Extreme Vaginal Discharge soreness at injection site, spotting for 2+ weeks WORKS AWESOME AT COMBATING THE LOADS OF CERVICAL MUCUS (WITH ODOR) I WAS EXPERIENCING FROM CERVICAL ECTROPION. F 30 14 days
6/17/2007
 2  Birth Control Hard to control weight. I had always had a problem with my weight so I did not think much at the time. After the first shot I pretty much bled (not hard) every day for 1.5 months. I tried the second shot and the bleeding stopped. I decided that due to my age and that I smoke I better stop birth control all together. So I was on it 1 year. Since then, I had to be on a 3 month leave from work because I had an emotional breakdown! I never put 2 and 2 together before I saw all of this depo info, by accident mind you. Maybe it is what caused it! Beware! F 36 1 years
6/17/2007
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 1  Birth Control Pain during intercourse, slight loss of libido My nurse, doctor and consultant were all surprised by this side effect, saying it was something they hadn't encountered before and initially tried to attribute it to lack of lubrication, although this was not the issue. Have also put a little weight on despite considerably improving diet and exercise regime. Having no periods was good, but lowering of mood, increase in sweating, body odour for the first time in my life was not worth it. Been off it for 6 months now and the primary symptom of pain during intercourse has not yet subsided. Hoping (really hoping!) it will go over the next 6-12 months. On a recent trip to the doctors I heard (with no names mentioned) another patient had had similar difficulties with her contraceptive that week - I was surprised as I had no idea these issues were so common, until reading this page. F 25 6 months
6/17/2007
 1  Contraception I had experienced many NEGATIVE side-effects including, but not limited to: abnormal periods (some lasting up to 2 months), upset stomach, diarrhea, fatigue, nausea, NO sex drive at all. This contraception method was not worth the hassle. Every day I had an upset stomach, no matter what I ate, even water didn't agree with my stomach. I was afraid to go out anywhere because my stomach was always upset and I was afraid of being in the bathroom the entire time. I had gotten ultrasounds and X-Rays done on my stomach, but Im was suspected to have some kind of stomach condition. A week after being off Depo, my stomach wasd already much better and felt normal like it did before I went on the drug. I also just switched backj to the pill...Triphasil 21. When on Depo Provera, I had absolutely no desire to have sex at all. Of course that had an effect on the relationship between my boyfriend and I. I was always too tired to have sex especially being a full time worker as well. I think I had sex like 4 times every six months, and that was mostly because I didn't want my relationship with him to end. The first summer I was on Depo, I had a two month-long period, which any w F 20 2 years
6/17/2007
 1  birth control acne, weight gain of 50 pds., depression, mood swings, eat 3x's what i used to, headaches, backpains, leg cramps, abdominal pains, blured vision, dizziness, hair loss, chest pains, and lack of sex then when I did have sex it hurt. F 22 2 years
6/17/2007
 1  To prevent pregnancy Extreme irritability, mood swing, cravings, 30 lb weight gain, severe gastrointestinal problems such as: Gastritis and IBS. I developed kidneys stones for some reason. Lowered immune system. To anyone thinking about going on this shot beware. I was on the shot for a total of 4 years. I started taking it in 2002 after I had my daughter. The first two years were ok, looking back in retrospect I def. had some mild GI symptoms and irritabiliy, plus I couldn't loose any weight. On the 3rd year, I developed kidney stones, then SEVERE IBS. I ended up in the hospital to destroy the kidney stones and had to see a specialist for my stomach problems (which cost thousands of dollars even with insurance). I would have panic attacks (prob. due to the IBS) and get nervous, and I was always hungry. This is the worse shot invented, and shame on the doctors who inject this into women!!! Never ever again will I put anything synthetic into my body. Women do your research before using any type of contreception. Some women can take this shot and never have a problem, while others like me, have devestating side effects. I have know been off the shot for about a year and am slowly start F 26 4 years
6/15/2007
 5  Stop heavy periods No negative side effects Since getting the shot, I've had more energy, more appetite control, and have lost more than 20 lbs. Sex drive better since I'm not worried about pregnancy. F 40 9 months
6/14/2007
 3  severe PMS lupus like symtoms,extreme fatigue, back pain, headaches, severe depression, moodswings, weight gain 30+ lbs, Boobs producing milk and leaking,lack of sex drive,no drive to do anything. at first i loved it no period.. but now after seeing numerous doctors i did some research and found out all my lupus like symtoms could be from the shot. I had to leave my job because i felt so sick all the time. Women need to let there dr's know about the side effects, my dr had never heard of any of these symptoms resulting from the shot F 24 6 months
6/14/2007
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 3  Endometriosis Constant headaches, leg and bone aches, stomach aches, depression, severe mood swings, weight gain (9 kg) constant bleeding for first three months, anxiety I was on this for 11 months for endo and it started out OK helping with pain but then the side effects got worse and worse. Depression and mood swings, anxiety, weight gain, went up two cup sizes in my bra, breast tenderness, stomach problems and stomach aches, period like cramps, my bones in my leg ached and still do, extreme fatigue, constant headaches and hair loss. I am now off it and I am still getting headaches, constant nausea, stomach aches and leg cramps which I think have been caused by the depo. I am also starting to have panic attacks and feel extremely anxious. I now wish I had never gone on it. F 11 months
6/14/2007

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