DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control Weight Gain of 18 lbs.; Increased Anxiety; Depression; Complete loss of sex drive; extreme breast tenderness; foot pain; loss of menstrual periods; vaginal dryness; hot flashes. I had one injection in December of 2008 in an emergency situation. I regret getting the Depo. With all of the side-effects people are enduring, it should be taken off the market. I haven't had a period yet and it's been 7 months since I got the injection. I've gained over 18 pounds and exercise is not helping one bit. I hope my hormone levels can be fixed soon. This is absolutely crazy! F 33 1 days
7/15/2009
 1  Contraception MASSIVE increase in appetite, lack of motivation, lack of sex drive. Horrendous. I was originally on Depo for 2 years and had very little problem with it, aside from a slight increase in appetite. After a 2 year break, I have recently had the injection again and am astounded at the increase in appetite. I am constantly hungry to the point of it being painful, and I amrequiring meals 2 or 3 times larger than normal. I am suffering a total lack of motivation to do anything, and a frustrating non-existent sex drive (previously it was extremely high). Awful shot, don't go near it! F 21
7/15/2009
 3  Birth Control and Cramps Weight gain, I stopped getting a menstral cycle, barely any acne, no headaches, no pms I was on Depo-Provera for 2 years. I finally decided to get off of the injection because I gained 40 pounds in one year without changing any of my eating habits. I hated the injection at first because I still got my period for about 4 months after my first injection. The bleeding would last for three weeks. I did consult a doctor who said that my uterus was just getting rid of the build up on the wall of the uterus. Then my period completely went away. I loved it. Plus I got less acne and felt one hundred percent. I did however stop getting the injections because of my upcoming wedding and wanting to lose the weight I gained. F 20 2 years
7/14/2009
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 1  To prevent pregnancy fatigue, weight gain, mood swings, depression, night sweats, pain in legs and feet, muscle pain in arm (where shot was given), prolonged spotting, lack of sex drive, lack of vaginal moisture, restless sleep I only chose this birth control method because my doctor suggested it since I cannot take the pill anymore because of high blood pressure. The first few weeks were fine, but at about the third week my mood drastically changed, I was getting agitated easily and crying for no reason. The worst part was the leg and feet pain, especially when wearing sandals and when trying to sleep at night. I still have a month and a half before this shot wears off and have been lightly bleed for two weeks. I have no intention of getting this again. F 26 1.5 months
7/10/2009
 1  contraceptive extreme weight gain, clinical depression, hair loss, ongoing side effects Please, if you are considering this method of contraception- CHOOSE ANOTHER METHOD! This is the worst thing to do to your body. Years later, I am still experiencing lasting hormonal imbalances caused by depo. F 38 12 months
7/9/2009
 2  unexplained bleeding I'm taking depo and its horrible, i have unexplained bleeding and had my period for 7 months last year. so they put me on pills which didn't stop my bledding, They decided too put me on depo, My mom agreed and i've been on it a year. I was 138 when i put on this shot and gained 30 pounds. I don't eat very much i munch during the day. but i was wondering if this is normal. My GYN said that I am supposed to be gaining weight but im not sure im suppossed to be gaining this much. And it is embarrassing because it is noticable. its horrible. anyone else have this? F 15 1 years
7/6/2009
 1  to stop heavy bleeding I spotted everyday for most of the 3 months....I did not continue taking Depo Provera. My emotions were wild, had migraines much more severe and often,I screamed at my boyfried regularly, moody!, argued over the smallest things! Everything seemed to "get on my nerves bad". I was nicknamed The Monster, because Norm had never seen me act this way before. My sister had also tried it, and I listened to her and her 2 teenagers describe "what a mean witch" my sister was. I have been told I am prone to Osteoperosis, and my doctor did not ask me anything about this. She did not warn me of the black box warning on the shot. I took only one shot of DepoP. I was supposed to go for the second shot on April 7th. I had a period in May, but now it is July 6 and I still have not had another period, just some spotting. F 47
7/6/2009
 4  BC back pains, anxiety, mood swings Although I am currently on my 2nd shot, I think it's an overall good form of BC. NO PERIOD so far! :) The back pain is tolerable BUT I could most definitely do without the occasional mood swings... F 18 5 months
7/5/2009
 4  PREVENT PREGANCY/NO PERIODS I TOOK THIS DRUG FOR 10 CONSECUTIVE YEARS. I HAD SEVERE BONE DENSITY LOSS AND 5 YEARS THUS FAR OF MAJOR HAIR LOSS. I AM NOT SURE WHAT OTHER BODILY FUNCTIONS HAVE BEEN NEGATIVELY AFFECTED BY THIS DRUG. I PRAY EVERYTHING WILL REVERT ITSELF. HAS ANYONE ELSE HAD HAIR LOSS??? IT DID AID IN KEEPING ME CALMER. I DIDN'T HAVE AS MANY MOOD SWINGS. F 41 10 years
7/4/2009
 1  To prevent pregnancy at the time Of course the big "W" weight gain,I too experienced some major mood disorders I got this injection only once and wouldn't recommend this to anyone, got it in November, should have been out of my system by Feb.my periods still aren't regular and I can't get pregnant for some reason F 30 1 days
7/3/2009
 1  the boyfriend wanted no periods mood swings, first month period lasted almost 2 months then no period at all. tired all the time. i didnt have a lack of sex drive that bad, even tho it greatly increased when i stopped taking it, i came here looking for information on the side effects when stopping the shot. i still havent had a period and its almost been a year since my last shot. i would say to anyone thinking about the shot DO NOT take it. the time shown on how long i took it is counting even when i stopped taking the shot, i only had 3 injections F 21 1 years
7/2/2009
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 2  birth control two periods a month for first three months,nausea,loss of appetite,dizziness,small seizures anyone heard of seizures with this medication? had a brief seizure while receiving 3rd shot,sent to hospital,doctors cant explain F 18 6 months
6/27/2009
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 5  pregnancy prevention TOTAL lack of sex drive. Ok for me, sad for my husband... I am currently in my second month of my first shot and it seems to be pretty effective. I would only complain about one major side effect, no desire for sex with my husband AT ALL. Although this could be because we have a now 9 week old baby boy and a 4 year old, and I am an at-home Mommy. At 25, this lack of sex drive is a little disturbing, considering I am so young, and my husband is a great lover. I kind of have to force myself to get "in the mood", but then don't enjoy the sex all that much because I KNOW that I wasn't really aroused. Other than that, no complaints, I've lost 17 of the 25 baby weight pounds that I gained. Diet and healthy lifestyle is key. F 25
6/23/2009
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 2  Highly irregular periods. Never-ending fatigue, bad abdominal pain, IBS (which I never had before going on Depo), weight gain (about 15 pounds), mild depression So while I am happy that I haven't bled in almost a year, the side effects are not worth it. I have heard of irregular bleeding after being on Depo. I can only hope that the irregularity is more like once every few months rather than three months straight like mine were before I got on the Depo. And after hearing about the possible osteoporosis, there's no way I'm getting the next shot. F 19 11 months
6/23/2009
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 1  Birth Control Weight gain, depression, moody, loss of bone density, anger, nausea, migraines, hot flashes... The first 3 months were not bad.. I actually lost weight... I did have morning sickness for some reason, but I was not pregnant because I wasn't sexually active at the time.. the next 3 months.. ugh .. the depression started to happen.. moodiness.. slight weight gain.. I also noticed that when the doctor gave me the shot in my arm.. I didn't have as much depression or anger.. I got it on the hip butt area.. and ugh.. I had really bad mood swings.. now after taking it over a year my husband just hates the shot.. he wants me off of it and to never go on it ever again .. I also have loss of bone density too.. so that sucks since I'm only 23 years old.. My last Dr. said this shot is so bad he wouldn't even recommend it to his daughter.. He wasn't going to even allow me to get it through his services.. so I had to tell him I would be off of it after this... besides I don't want to be on it anymore.. and if he thinks it's that bad.. I know it can't be good for my body .. too many side effects .. I mean I like being covered for 3 months.. and not have to worry about a pill.. but I guess I'll just go on a pill and see if they can regulate some hormones.. I'm on Ortho tri cyclen right now and it has taken away the hot flashes.. so yay.. and also it's helped with moodiness.. so I think I'll just stick with this pill :) F 23 1.5 years
6/23/2009
 1  to control menstrual cycle leg cramps,headaches,abdominal pain,degenerative disc & joint disease,fatigue,weight gain,lower back pain constantly,neck pain,emotional side effects, joint pain throughout body...etc. After finding out the side effects from this website and information given to me from my neice, I will not suggest anyone to be given this shot. It has done extreme damage to certain parts of my body. I have no insurance and cannot afford the tests needed to determine the damage this shot has caused. The doctor never bothered to tell me the side effects other than weight gain and possible breakthrough bleeding. He also neglected to tell me that you are only suppose to take this shot no longer than 5 years. I have been on it for 18 years, and have not had a period in 17 1/2 years. I was asking my recent doctor about this shot, she took me off of it IMMEDIATELY after realizing that I have been on it for so long. If any of you have any other information about this shot, please email me. God Bless You! F 38 18 years
6/22/2009
 1  ovarian cysts depression, anxiety, 20 pound weight gain in a matter of two years (by the way i am a health freak and do excercise three times a week), severe acne, kidney stones, kidney problems, dehydration problems,and horrible migraines. the whole reason i had to take depo was because of ovarian cysts, but yet i am still gettin cysts every month almost. this is ridiculous i am going through bone and kidney problems at 16 years old, i would definitely recommend to anyone, to get off of this monster! F 16 2 years
6/22/2009
 5  Endometriosis A couple of years ago my doc did a bone scan and I was pre-ostoporosis. I did not gain a lot of weight on depo but I had a really hard time losing weight. I mean it takes everything just to lose a pound. In the last year I started to have break through bleeding with the depo. The depo worked extermely well for me for the last 8 years. My doc recently had me have a hysterectomy because the depo wasn't working anymore. I agree it was time. F 39 8 years
6/20/2009
 5  Birth Control/ No Period Vaginal Dryness I have had 2 Bone Scans both came back fine.I am very happy and will continue for as long as I can. F 25 11 years
6/20/2009
 5  Birth Control Medium to light spotting continuously for a few months, then completely gone. People are rediculous. It acutally only accounts for about 5 pounds of weight gain. The rest of it . . . change your diet and start exercising. The exercise will also help with your sex drive. As for all the other problems, there are probably some other underlying physical or mental issues that need to be addressed and that taking the depo shot just will not "cure". Go back to your doctor and get checked out, don't hate on the DEPO. F 34 3 years
6/18/2009

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