DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Long heavy period Head Aches, Lower back ache for about 24 hours after the shot, leg cramps and a dull ache in the cheek were the shot was given which does not go away right away. I was hospitalized May 8th,2007 for severe Anemia. My iron level was at 4 and for a female my age your iron level should be at 12. The cause of the severe anemia was a prolonged and heavy period that was on going for three weeks. I was given a blood transfusion as well as the depo shot. I was not happy to have the shot, but it was that or a D&C. I opted for the shot to stop my period. It did for a few weeks but it returned. I just recieved another shot yesterday and although I have not had much of the side effects many have experienced does not mean I won't. I have a great gyno and I will have to not only now have a d&c I will also have to have exploratory surgery do to my period issue. I suggest to anyone who bleeds more than two weeks to go to your gyno and if they do not have the answer then try another one. Side effects come with every drug you take and so I opt to not take the shot again after reading all this but reading that many of you have had periods for a prolonged t F 26 2 months
6/12/2007
 1  birth control anxiety, depression, weight gain, hair loss, muscle aches, stomach problems all of which kept getting worse until i realized it was the depo causing them. This is the worst bc in the world I have never had so many health problems in all my life. Coming off of depo was a nightmare but I am so glad i have. Last shot was exactly 6 months ago and am finally starting to feel human again. I literally thought I would die. Started having panic attacks, nausea, vomiting lost 30 lbs in a matter of weeks which i feel kept releasing this poison into my system since depo is stored in the fat. Countless dr visits and no one could find anything wrong. Only 1 dr would believe me that it was the depo. AF has still not returned and who knows if it ever will. Gyn wants to give hormones I said NO WAY!!! never again. Good Luck to all of you going through this just believe there is a light at the end of the tunnel. F 41 8 years
6/12/2007
 1  Birth control while breastfeeding Complete loss of libido. Sore, almost painful sex. Approximatly 10 lb weight gain per shot. High depression. Very low self esteem. It worked as a birth control in more ways than one. I was so depressed and sex was so 'not' fun that my husband and I had sex less than twice a month for over 9 months and those were only for him. I have been off it for a month and though I haven't lost the weight I gained, I feel so much better overall and actually have a sex drive now. F 26 3 times
6/12/2007
 1  birth control 13 pound weight gain in 4 months, mood swings, acne 7 years ago I lost 30 pounds with Weight Watchers. After the shot I started to gain 1-2 pounds per WEEK. This was extremely frustrating for someone who has tried so hard to maintain a weight loss. No one can tell me I'm munching too much because I keep track of everything I eat and all my exercise. I got my shot on February 2 and as of last night I've gained 13 pounds. It has been over 4 months since I got my shot and I'm still gaining weight. I will never use this again. We were considering another baby eventually but I still haven't had a period and from what I'm reading here, it could be a long time before I do. I've had some of the mood issues but certainly the biggest problem for me has been the weight gain. I'm hopeful the drug will start to leave my system soon and I'll be able to start losing weight again. Fortunately, I do not have other problems, like heavy bleeding or extremely painful periods. But I do have a history of blood clots so my birth control options are F 31 1 times
6/12/2007
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 1  endo Weight Gain, Abdominal pain, acne, thinning hair, mood swings, swelling I started taking this medication 6 years ago for endo. I worked extremely well in the beginning. The pains subsided and my period completely stopped. After about three years the weight gain came and I have a hard time keeping a steady weight. The pains from endo persisted after some time and also grew in time. I have struggled with acne forever and the shot never helped. Looking for a new help with the endo I came across a Dr. Albee and read about his clinic and found out stuff that my doctor never mentioned. We talked about how the shot decreases the bone density and there is a risk that you will not ovulate again, that chance is rare but it is a possibility. I am now off the shot for about a week and nothing has happened. I don't know what to expect. Took a pregnacy test, it's a negative so here we go with not knowing what to expect. F 26 6 years
6/10/2007
 1  Birth Control I was moody and cranky a lot of the time and those around me said I was almost unbearable. I am normally easy going and get along well with everyone. I also bled for a month straight in the third month both times I took it and had to get on birth control pills to stop my period. It may work for others, but i think it's awful and does not work well for me at all. I wonder if I may have had an allergic effect from it that induced the bleeding. F 26 6 months
6/7/2007
 1  prevent pregnancy i gained 50 lbs on depo, the only good thing i thought was not having a period but i have been off the shot almost 2 years and still have not had a period. this i worry about everyday as eventually i would like to have kids and not having a period is not normal or healthy. also, the weight i gained i still have not been able to drop. I would never ever take this shot again. F 20 3 years
6/6/2007
 4  birth control significant weight gain, joint pain, vaginal dryness, painful intercourse the weight wasn't a big deal, and the joint pain I attributed to a car wreck ten years ago. the dryness was beginning to become a bother, but the pain was what was the deciding factor. my dr told me to use lubrication every time, and change positions. after that appointment, while waiting for the next, I experienced a very scary event, which I can most explain like losing your plug in childbirth. very thick, black blood, not mucousy, but very gross. depo has worked for me wonderfully, but the side effects are starting to weigh out over the good it has done for me. before, I had no problems, only that I can't remember a pill every day. the intercourse delimma is the only deciding factor in changing birth control. F 28 1.25 years
6/3/2007
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 5  menstrual migraines, bc hair loss, weight gain I was on depo for 6 years, I went on it because a dr. suggested it to help with my monthly migraines. I averaged 3 or so a month. Once on it I dropped to around 3 a year. Since I had menstrual migraines I was told that pills would more then likely make them worse because of the hormone fluctuation. I stopped depo in May of 2006 because my husband and I started thinking about wanting kids. By August I started to spot and by November I had started having a regular cycle. I didn't really have to many side effects while on the shot except the weight gain (45lbs in 6 years) and hair loss. My migraines have returned but usually only get one about a week before I start my period. F 30 6 years
5/30/2007
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 4  Birth Control, Cramps Loss of sex drive, lower back pain, spotting, depression, occasional cramps Well, I haven't gotten pregnant on it so thats a plus, but the loss of sex drive is putting a strain on my relationship, but over all I love not having a period & the spotting is about the same time I would get my period (lasts about a week) but I am depressed & worry a lot more than I used to. Overall, I would recommend it. F 19 4 months
5/30/2007
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 3  Birth Control weight gain, loss of sex drive I took depo for about 9 years. I realized I was gaining weight but the lack of a menstrual cycle made it worth it. I have been off it for 3 yrs. Now i need to have some cervical tissue removed that may be cancerious. No idea if depo had anything to do with it, but now I question my decision to stay on it for so long. F 31 9 days
5/29/2007
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 1  avoiding pregnancy weight loss, severe stomach problems and heartburn, palpitations, loss of appetite, bone loss, anxiety. I got my first(and only)shot in July. Within the first month I began to have problems with my knees and hips. By the second month I had lost 5lbs, which isn't normal considering I only weighed 116lbs. Now its been almost a year and i've lost 5 more lbs and suffer from extreme indigestion and take lots of medications. I was a very healthy 21 yr. old when i got this shot and now I suffer from physical ailments of someone over 40. This shot is a quick fix, but its not worth it! F 22 3 months
5/25/2007
 1  Birth Controll Severe depression(which I had to begin with this made it worse), EXTREME irritability, Lowered sex drive, lack of energy, pain in left side of my body (mainly my joints, specifically ankle, knee, wrist, and elbow.)Mood swings, Loss of appetite, weight loss I thought this would be a great idea but I was wrong, I got the shot and that same day my moods starting shifting crazily. This shot is causing nothing but trouble, its put my realtionship with my boyfriend on rocky ground because everything he does irritates me. which it never used to untill I got this. I can hardly stand for long cause my left ankle and knee hurt so bad, and my left wrist aches so much I try to avoid using it. ONly 2 more months of this crap. I'm going back on the pill, this crap isnt worth it. F 18 1 months
5/25/2007
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 2  birth control, stop period significant weight gain(40 lbs), increased a boob size 36a-> 36/38 b/c, stopped period I was also on anti-depressant, remerol at the time and gained 40 lbs!! after time I figured that being without a period is abnormal and probably not good for the body so I got off... what made me change my mind the most was the weight gain though F 19 7 months
5/23/2007
 5  Pain management difficulty in loosing weight when i do gain it. I've been on the shots for 8 years. I would not give them up for anything! I have always had extreme menstral pain, then in 1998 diagnosed with Fibromyalgia. Not only has the shots eliminated my periods (god send)I don't have to deal with the excruciating pain of a period which was adding to the pain of the Firbomyalgia. My Fibro pain has decreased significately as well. I've rollercoastered with weight all my life, so it's just a little harder. For me IT'S WORTH IT! I have my tubes tied, I'm a single mom and grandma and yes I have absolutely no sex drive which for me works. It lets me focus on my kids. I'd rather be a little overweight and single than suffer all that pain again! F 44 8 years
5/22/2007
 1  Birth Control Weight Gain, Impossible to lose weight, severe mood swings to the point where I thought I was suffering post natal depression, no sex drive whatsoever. Felt like the end of the world most days I was due to have my next injection today but told the nurse ponit blank I didn't want it. Her comments to me basically implied that everything I told her was down to me and not the side effects of the drug. She was very reluctant to not give it me. I have now insisted that they try the coil. Fingers crossed I'll feel better! They shouldn't make you feel guilty for wanting to come off it. F 31 12 months
5/22/2007
 1  contraceptive loss of scalp hair, increased facial hair, ibs, anxiety,agoraphobia, abdominal pain, migraines, weight gain, acne, depression Please contact me if you know when the side effects will end i stopped taking the shot in December If someone would have told me what i know now i never would have taken this shit. i was a healthy 17 yr old when i started. i'm now 24 and i have problems leaving the house because i feel like i'm going to lose my bowels. i had a brief stint of agoraphobia and almost didn't graduate from college because of it F 24 7 years
5/22/2007
 3  Contraceptive Weight gain 28lbs, loss of sex drive, no energy If I had known that this drug was going to make me put on around 7lbs each year I would have never started taking it. You are warned that you may put on weight but not that it will continue. My sex drive is zero. I hate it, I am due to have my next shot in 2 days but I am not going to have it, however, I am very worried about what side effects will happen once I stop taking it. The only good thing is that I don't have babies or periods. If I could turn back the clock to when this drug was offered to me I would not take it again. F 38 4 years
5/19/2007
 3  painful periods I have acne and mood swings (less than with my period) depression but not sure if it is b/c of shot or life. I have had weight gain but that was (I thought) from the anti-depressants I was on. Not b/c of the shot but b/c of some taumatic things in my life. I'm off of the anti-depressants and did lose 20 lbs, but can't seem to lose the other 30 lbs. I did have a bone density test and its very low, not quit osteoporosis but getting there. No sex drive, but I thought it was b/c of some stuff I'd been through not b/c of the shot. I'm thinking about stopping the shot, given my bone density and what I've read here. But I have extremely painful periods and heavy bleeding. This shot has been a godsent for that. I also have horrible mood swings and become suicidal when I get my periods, not to mention that me family doesn't dare go near me for a week before and during my period. I'm am scared to stay on it, but the alternative (having my period) is very bad for me too. I hate the thought of having a period again. I'd almost rather die than have to go through what it is that I go through. I'm just at a loss. Please if anyone has any thoughts on what I could do to help with the period symptoms I would appreciate you input. F 36 10 years
5/19/2007
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 1  contraceptive severe depression, loss of appetite AWFUL experience with this drug. I was so emotionally messed-up during the three months I was on this drug that I was diagnosed with Borderline Personality Disorder and I had to take "Incompletes" in a couple of college classes. The worst part: once you get "the shot" you're stuck with the side effects for 3 months. If you've ever been diagnosed with depression, even if you're fine before considering this drug, please discuss other options with your doctor! F 31 90 days
5/19/2007
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