DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  cysts and birth control Pain, severe mood swings, heavy painful clotting, no libido, weight gain constipation. I room the depo shot for two years in the past with no real side effects so I decided to start to retake it when I restarted my birth control and the side effects have been unreal. I've had Severe pain when in one position, pain in my hips and knees would actually wake me in my sleep, turning into a PSYCHO to the point I know I'm being nasty and I know I am but I can't even stop it no matter how bad I try, severe rage for no reason or very little provoking. Its not even a period im getting its extremely painful and all it is, is clots. Before when I was on it the weight gain was unreal almost fifty pounds after I stopped taking it it melted off so it wasnt my eating habits. my libido is gone and to be blunt I had NO issue with that before. The constipation is terrible and when I do go its painful, it will get to the point my lower abdomen is pushed out. I cannot wait for this to flush out of my system. And I got two more miserable months to wait. I just don't understand why I had no symptoms before but now I do. F 20 2.5 years
reg. dose 1X O
5/15/2011
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 1  Birth Control Fatigue, Mood Swings, Anxiety, Back and Body Aches, Weight Gain, Digestive Upsets, Acne, Hair Loss I started Depo Provera in Feb 1998 after the birth of my first daughter..For the first couple of years it was a micacle drug until I had my first panic attack which at the time I related to losing my father suddenly in 2001. As my moods progressively got worse my Doctor at the time suggested that I have Depo every 8 weeks..and take a daily dose of Zoloft. About 12 months ago my moods and panic got so severe that I couldn't even drive my daughter to school :-( About this time I changed doctors and the first thing discussed was the Depo and the effect it can have on mental health so in December 2010 I had my last shot EVER!! Im now undergoing extensive medical tests for hormone imbalance, pituitary and adrenal glands, blood sugars etc etc the list goes on and on...One month after my last shot was due Im slowly starting to feel a little 'normal again'. Oh and by the way I forgot to mention that I was 72 kg after my daughters birth and I now weight close to 100 kg :-( F 32 13 years
150mg 1X O
5/14/2011
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 1  birthcontrol every bad side effect asotiated with the shot it the worst every bad side effect im excperencein its so bad im consaultin a lawyer about fileing a law suit its ruining my life and its hard 2 function as a human its the worst decision i ever made its ruining my marriage from the mood swings im not the mom i used 2 b h have dizziness light headness ever day allday aneixty im spaced out weird vision and i dont feel like my self not 2 mention no period 4 2 months ive been 2 the doct 5 times allready he said bc shot had all kindsof test done bc shot and its been a little over 3 months and there side effects r still here my doct said it stays in ur system longer then 3months worst discion ever just want 2 b normal again 25
1X O
5/14/2011
 5  Prevent Pregnancy None, After reading all these terrible things I did miss periods and may have gained weight, maybe acne.. I have been on depo since i was 17, i am now 21 sure i have gained weight and have a tiny bit of acne but i cannot blame that on depo as it may just be due to the fact i am grown up. Call me crazy but i think it was great! I am only now going off it because I has been shown to decrease bone mass, I am very active and haven't seen any signs of this but i have recently been diagnosed with scoliosis (crooked spine) which can be degenerative so I decided to try something else jussst in case. Im more afraid to try a new BC than to stay on this one. Wish everyone the best of luck but don't let these horrible reviews scare you. There are bad reviews on every BC, I read these just now and got freaked out and I have been on it symptom free for 3 years. F 21 3 years
1X O
5/12/2011
 1  birth control severe loss of libido, mood swings, anger, more acne, weight gain (7-14lb), painful sex, vaginal dryness I have been off depo jab for 6 weeks now and am on the mini pill instead, after complaining about side effects to Dr. My libido is back to normal and I am not experiencing pain during sex. My skin is clearer and I feel calmer and am not experiencing the sudden mood swings. F 35 15 months
1X O
5/11/2011
 4  Not Estrogen based The only side effect I had while on it, was mild irratating headaches that would last for days. My problems started when I stopped taking Depo. Excessive fatigue, Night sweats, thrist, Abdominal and Flank pain, rash on my legs, loss of appitite, nausea, breast tenderness. I had these for 5 months till I had my first period then it all stopped. During the time I was coming off Depo, I was thinking I had something seroiusly wrong with me (Cancer or Kidney Failure). Almost weekly Urgent Care visits for pain and sickness. I had Ultrasounds and Cat Scans. My Dr's were stumped. Even though Depo worked fine for me it's not worth the pain and suffering I went through to come off. Completely upset my family and work lives. F 44 1 years
1X O
5/9/2011
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 1  Prevent pregnancy Spotting, extreme anger/mood swings, incredibly dry/itchy skin, acne, low sex drive, vaginal dryness, anxiety. I deeply regret the decision to get the shot. It makes me want to cry just reading these posts knowing that I could have done my research and prevented all of this. I thought it would be a perk to not get my period every month but instead Ive bled everyday for the past month. I have worse acne than Ive ever had in my life....even my scalp is breaking out! It hurts to have sex because of the vaginal dryness. Ive noticed that I've been EXTREMELY angry with everyone in my life for every stupid little thing. I feel like I have panic attacks that last all day. The convenience of not having to take a pill everyday just isn't worth the side effects. Its one of the worst decisions I've ever made. I wont be going back to get a 2nd shot and I cant wait to get this garbage out of my system. F 23 1 months
1 shot 1X AN
5/6/2011
 1  pcos, endometriosis, andynemiosis severe severe anger mood changes severe depression anxiety crying spells rage just not feeling right PLEASE IM BEGGING YOU DO NO EVER EVER EVER TAKE THIS DRUG!!!!!!!!! i literally want to kill people i become so inraged for no reason i cant see i cant speak i cant remember my name where i am or whats going on ive never felt this way off bc i tried nuva ring and i had the same feelings not as intense i took it out and after a week was back to normal i tried again because my doctor told me it was me and that it was not a side effect yea right some how she talked me into the shot this is so horrible i cant take it anymore i want to kill myself if i didnt have a child that had no where to go i probably would have already i feel soooo crazy i feel psychotic i cant think i cant function i dont want to move i dont want to talk i dont want to eat i dont want to do anything but cry i want this out of me so bad omg never ever again all of us should get together and sue this company for the pain and distress this has caused us in our lives this is ridiculous ive never felt this way in my life im soo scared F 23 3 months
1X M
5/6/2011
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 2  Prevent pregnancy rarely feel the urge to want to have sex, my depression increased a lot, anxiety increased, got more anti-social, feel constant tiredness and lack of energy, moodiness, i have also noticed i have i get sick easier and my allergies raised up since i have been on this, awful stomach pains during sex, vagina dryness, noticed every since I've been on this i developed more mucus in my throat, my breathing got REALLY BAD. i can only breath like 70%, not a 100% and all this happened 2 weeks after getting the shot. DON'T GET IT. IT'S HELL. Definitely not worth all the side effects you get from this drug. I don't understand why doctors are giving this out, it's terrible. And i hear so many woman still getting pregnant from it. I don't trust it. F 18 2 months
1X day
5/5/2011
 1  Essure Procedure Ridiculous bleeding- I have been bleeding for 11 weeks now, with no end in site. Passing clots, having headaches. No one told me this was a risk when I received the injection. I had the shot so I could get the Essure procedure. I would NEVER recommend this to anyone. It has ruined my sex life with my husband. I reported this to the Pfizer group. My doctor now wants me to try a BC pill to see if I can build up my lining in my uterus. If this does not stop it I don't know what will. But I will not bleed for the rest of my life. It is a horrible drug. Do not take it F 34 1 times
1X O
5/3/2011
 2  regulate periods, birth control insomnia, fatigue, frequent urination, appetite fluctuations, mild weight gain, terrible spotting and breakthrough bleeding. i lost hair a lot before beginning depo shot, after, the hair loss almost stopped. i had no period for the first two months of the shot, the last month i bled or spotted constantly, sometimes light spotting, sometimes a flow like a normal period. it caused me to have to urinate more often. i experienced appetite fluctuation, some days i was always hungry, some days i couldn't eat. i gained a 5 pounds over 3 months (not too bad). i experienced constant fatigue and insomnia as well as a loss in ability to concentrate. overall i would not recommend this to anyone, nor will i ever take the depo shot again. F 15 3 months
150 mg 1X O
5/1/2011
 1  Birth Control Major mood swings, weight gain, skin sensitivity, decrease in sexual desire, acne.....the list could go on forever. I had such drastic mood swings and weight gain I went to my physician about it. My female doctor told me I was just tricked into thinking I was hungry and to stop eating so much. She didn't even ask to look at my food journals. My family physician said his average patients doubled their weight on the shot and that I should have never gotten the last shot since it is definitely not safe to be on for longer than a year. I was referred to a dietician who set up food classes and journaling for me. I ate between 1200-1300 calories a day, low sugar, 30g fiber, low fat, etc....did everything right and still GAINED. At the height I had gained a little over 80 lbs. After about a year I started coming down off the mood swings a bit and lost the first 20 lbs months after the exercise/food plan failed to work and I went back to normal activity/eating habits. 20 lbs in less than a month and a half. It is still gradually coming down and though I still have problems with my moods I am a LOT closer to who I was before I started getting the shots. I would not recommend it for anyone. Yes, all other forms of birth control have given me problems either increasing migraines or weight gain, so that was nothing new, the HUGE mood and DRASTIC weight gain is what floored me. I had my daughter, lost 80 lbs and was smaller than before I got pregnant. I started the shots and it was a sudden, drastic gain that continued until after I stopped taking the shots. My physician said he would NEVER recommend i F 25 1.3 years
avg 1X O
4/29/2011
 2  to prevent pregnancy and regulate periods headaches, fatigue, really bad mood swings, depression, partially anti-social, hard to get out of bed, hair dryness, hair loss(falling out when brushed or washed), loss of appetite, weight loss it has completely changed who i am!!!! F 18 7 months
1X M
4/24/2011
 3  Ovarian Fibroids/Prevent pregnancy I just started the shot in Feb of 2011. I do have the weight gain, hot and cold flashes, and painful bleeding because of my ovarian fibroids. I am on the shot because i have ovarian fibroids, want to prevent another pregnancy, and i have chronic high blood pressure that i got during my pregnancy that didn't go away.My doctor said that the shot was the only option for me because it is just progesterone.She said i can't take the pill because the estrogen would really raise my blood pressure.I am on other meds to control my bp as well.The weight gain hasn't been bad in fact i have lost some since my last dr appt 2 weeks ago.My hot and cold flashes are combo of the shot and my bp meds.The bleeding is painful because of my ovarian fibroids.My doc said that she wanted to stop my cycle completely because they will be painful and since i started bleeding a few days ago man was she right.The pain is excruciating.It's not due to the shot, but due to my fibroids.She said that the shot would take some time to help and until then if i had the bleeding it would painful.i get the shot once every 3 months so i am due in May for next dose.I really like it i haven't had any bad side effects and it seems to help with my pain in the long run. F 34 2 months
unkown 1X O
4/22/2011
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 4  Prevent Pregnancy Weight gain, Lighter periods, Irregular spotting Aside from a substantial weight gain and the irregular spotting I have no other complaints about this product. I've used this product off and on for the past 9 years and the two side effects listed above are the only ones I have experienced. F 25 1 years
1X AN
4/20/2011
 1  Stop pregnancy and period Extreme fatigue, lightheadedness, constipation, depression, pain in joints, bladder and abdominal pressure, frequent urination, bloating, Vitamin D deficiency, excessive body hair growth, body weakness, poor circulation, obsessive thoughts, extreme paranoia, increased acne, poor digestion, hot and cold flashes, mood swings, difficulty keeping visual focus, overall body aches, pain, and lethargy, thoughts of suicide, genital discharge, incontinence, insomnia, easy bruising, etc. I was highly active and very energetic, healthy, and not overweight. BECAUSE OF DEPO I HAVE SUFFERED SINCE BEING INJECTED. I have no doubts about Depo being the root cause of my symptoms. After going months and not knowing what was wrong with me, I went to a specialist. The endocrinologist ran tests, and diagnosed me with HYPOTHYROIDISM. No doctor, nurse, or lawyer will believe the Depo is the cause, but I know it is. I didn't develop any problems causing me to be confined in my house for four months. Don't let your belief be swayed because there are thousands of women who have suffered like I have. If you are having symptoms as I described, go to an Endocrinologist. You will likely get a diagnosis and get treatment before it is too late. I now have A DISEASE FOR LIFE. I will never take Depo again. All this lifelong suffering from a single shot. F 18 4 months
150 1X O
4/19/2011
Email
 1  painful periods PANIC ATTACKS, ANXIETY, HAIR LOSS, LOW BLOOD SUGAR, AGORAPHOBIA, FEARS, DEPRESSION DO NOT TAKE IT, THIS IS PURE POISON!!! IT WILL RUIN YOUR LIFE AND THERE'S NO WAY BACK!! F 44 30 months
1X O
4/19/2011
 5  prevent pregnancy Beginning brown discharge that went away, around the time for my next shot i feel light bloading, eventually have no period. Ever. In the beginning brown discharge and eventually no period. I cant even remember the last time i had a period and i dont have any more discharges either. I LOVE depo it is fast, non-complicated and reliable. But it is not for most women!!! if you do not react normally to other birth control methods such as the pill or ring you will probably react horribly to Depo (weight gain, mood swings). As a teenager i had light periods and no weight problem might be why Depo works great for me. My doctor said now that i am a long term user i need to take Calcium Pills and exercise regularly, which i do :) F 24 5 years
1X day
4/18/2011
Email
 1  Birth Control Acne, bloating, mood changes, constant bleeding, urges to cry, loss of motivation. Worst birth control method I have ever taken. I started it to get away from the estrogen in other birth control options to control my migraines and it was not worth it. I initially had very light bleeding for about the length of a normal period and then a couple weeks later I started bleeding again and have not stopped for two months. I definitely will not be getting my second shot. The worst of it all to is that my doctor said i would have slight spotting and weight gain and that is not what happened. Way worse! F 22 3 months
1X O
4/17/2011
 1  not to have a period weight gain, personality switched from being extremely laid back and nice to being a totaly different person, constant period. I would NOT recommend this drug to anyone. I've been on it twice. the first time, it was fine, i didnt have my period and i only gained 5 pounds. This time around its horrible, Ive gained 20 pounds so far in the 4 months i've been on it. I already have major depression but I've been able to manage it myself but since i've been on this, I've hit rock bottom. I'm constantly wanting to kill myself. I can go from being my usual happy self to either snapping at someone or crying over the stupidest crap. My personality has changed completely, I've gone from being laid back, caring and sweet to being a total bitch to everyone.I'm quick to snap at anyone and thats not like me. I went back on it to get off my period but no, the last 4 months, I've had a constant period, not full-on but its not right. Its not even spotting or anything just its been constant since i went back on it. I also shake alot, have trouble sleeping and when i do sleep, i have trouble getting up. I wish that this stupid drug would be taken off the market so that nobody else has to go through this crap. F 23 4 months
1X AN
4/16/2011
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