DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Extreme mood changes, physical and emotional numbness, gained over 20lbs., constant headaches, loss of sex drive. My doctor did not fill me in on the serious side effects until a year later when I started to question things and he straight out came clean with me and admitted it's all due to the depo injection. I can no longer take any birth control pills due to a blood disorder and this seemed to be the safe way out for the time being. I am no longer taking the injections and now worried about long term side effects. It does seem to be a very convenient form of birth control but its risks are panning out to be more serious and I do not recommend the depo injection to anyone. I am sorry I made the decision to take the injections. F 32 1 years
9/10/2007
 1  safe for breast-feeding Please stop this medication. Only side effect while on was weight gain. It is when you stop the true side effects come out. Hormonal imbalance(high testerone and high cortisol levels and normal to low estrogen, infertility, became polycystic, hair loss, joint pain, depression and inability to loose weight, insominia, insulin resistant. I was 25 when introduced to depo. I just had my son (who I got pregnant with while on regular birth control) and they ask if I wanted to breast feeding then told me the only thing I could take was depo. So being young and it new I agreed. Loved it at first no periods, but had weight gain I thought no big deal. My husband was mad told me not to take it. Should of listened. I stopped taking at 27 to try and get pregnant. I couldnt get a period so doc put me on birth control to start my periods finally a period after a year. Then trying to get pregnant. I did get pregnant at 30 miscarried told just a percentage. Then got pregnant at 31 miscarried. Finally doc start to investigate. Relized I had PCOS and body did not produce enough progesterone when pregnant to hold baby. I am now 35 still have not been able to get pregnant, tried fertility pills nothing is working. Periods still not back to my normal 28 cycle. It has been 8yrs and hormonally I am still a wreck. Went to new MD and she ran F 35 2 days
9/10/2007
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 2  To control heavy bleeding Weight gain, joint pain, skin irratations, water retention, hair loss.Heavy bleeding to light constant bleeding that never stopped. I do not recommend this for anyone F 35 6 months
9/9/2007
 5  birth control weight gain I loved Depo! I was on it for four years and the only side effect I had was weight gain of about 15 lbs. I had no periods but mild spotting occassionally. When I went off off it, I was able to get pregnant about a year later with no problems. I highly recommend it! F 26 4 years
9/8/2007
 1  Birth Control weight gain, loss of sex drive, acne I went on depo after having my daughter in October 2005. My doctor recommended it since I was breast feeding. At first I really liked it. Then I noticed that I was gaining weight(after losing all of the baby weight) and had very little sex drive. I just attributed this to motherhood and change of hormones after pregnancy. I also always seemed to have at least one big pimple on my face which was not normal for me. my last shot was near the end of January 2007 and the good news is my face cleared up immediately but I still have not had a period since the shot wore off in April. We are trying to have another baby and have no idea how long it will take. Hopefully not too much longer. I WOULD NOT recommend this shot for anyone who wants to pregnant soon after stopping the shot. I have been very frustrated this summer and never plan to go on the shot again. I have done research and there are other options to women who are nursing. AVOID THIS AT ALL COSTS! F 27 18 months
9/7/2007
 1  Birth control OSTEOPOROSIS!!!! DO NOT TAKE THIS MEDICATION! This should be Illegal! I had Osteoporosis at age 26! I started seeing a menapause specialist for bone density issues at 26! F 27 9 years
9/6/2007
 2  birth control, strong periods Hair loss, weight gain, moodiness, severe anxiety. F 26 4 years
9/5/2007
 4  birth control/stop heavy cycle no cycle so no cramps, head aches and irritability Started taking after my 10year old son was born and never seemed to have a problem except for occasional break through bleeding (clots). Came off around 4 1/2 years ago to have my three year old daughter, took me around 5 months to start having regular cycles again and then 6 months to get pregnant-which was probable pretty good considering my age and the depo. Went back on the depo at my 6weeks postpartum appt. Having break though bleeding again, and since learning that oseoporosis runs in my family I am starting to get really concerned about that side affect. I am gettting a bone scan as soon as possible and hoping that all my years of walking walking walking (weight bearing exercise) will be in my favor. If the scan does show damage I will stop the depo and if I have to, will just opt for a partial historectomy to stop the heavy cycles. My mother was also anemic from heavy cycles. F 42 10 years
8/31/2007
 5  Prevent pregnancy None - all good really, a tiny weight gain but that could have been down to age/unhealthy eating. No periods, no period pains. I have been on depo for just over 10 yrs, a long time! So I thought i'd give my body a break. The only side effect I have had in coming off the drug is sore breasts, this has lasted for 4-6 weeks now but it is getting better. Maybe I will have more side effects but so far so good. My partner thinks I have been short tempered, maybe I have but i've not noticed it. F 29 10 years
8/30/2007
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 4  so I won't die bleeding->hemophilia A lot of acne, minor weight gain (but I'm taking another medication that also says minor weight gain, so I don't know which one it is), cravings for fruits (especially watermelon. I almost ate half a watermelon yesterday) I didn't think the side-effects were too bad. I was put on the pill because normal birth control pills would make my migraines worse. My only big complain as a college student is that I have been having the worse acne breakouts of my life. I went on my first date with my current boyfriend the day I got the shot and he must think I always have horrible acne. F 19 2 months
8/28/2007
 1  migraines due to hormones on menses heavy spotting for 4 months on depro for 4 months,I don't dare not wear a panty liner, severe depression, night sweats, loss of libido, aching joints in knees and elbows I went on depro to prevent my migranines (dr's suggestion). It did stop the migraines, I did get headaches but nothing close to the severe migraines I suffered monthly for 20 years. However, the depression started, night sweats and aching knees and elbows. Complete loss of libido. Feeling of being in a "black hole, void, like nothing matters" I am definitely going off depro, and will take back the migraines instead of this hopelessness I am expreiencing. Have the best husband, who is understanding and patience with me at this time in my life. e-mail me if you want more details. F 49 4 months
8/28/2007
 5  irregular/debilitating periods After the first two years w/ few side effects the shot was changed (injection location) to my upper thighs instead of butt. I have since experienced dimpling at the site which hasn't shown any sign of healing/going away in a year. All things concidered I've been extreemly pleased with this shot. I haven't felt an ounce of pain or seen a drop of blood in almost 2 1/2 years though it did take about 6 months to adjust. No weight gain. I do experience notable vaginal dryness but it hasn't affected my sex drive. I am concerned about the dimples in my legs however. My doctor has one other similar case but no one seems to be able to offer me any explanaition for the reaction or any geuss as to whether these are now permanant markings. I've had no reaction in the shoulder, butt, or abdomin. If theres any one out there who's noticed something similar and might have found a better answer than just changing the injection sight I would love to hear from you. F 23 3 days
8/27/2007
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 1  birth control excessive weight gain, extreme circulation issues (arms falling asleep all the time, sometimes legs too), headaches, body aches, back aches, dizziness, vericose veins, acne, extremely diminished sex drive, excessive bleeding, depression, mood swings, constant fatigue (may be others that have yet to be determined thus far as I have not yet had bone density measurement or know if I am able to conceive) Thank you for your effort. I had no significant health issues prior to taking Depro, had maintained the same weight, give or take 5 lbs., for many yrs., and had no issue taking the weight off when it did fluxuate. I received my last shot in Nov. of 2006 (I received four shots total) and today am still experiencing many side effects. While taking Depro, my symptoms included excessive weight gain, major circulation issues (my arms would fall asleep repeatedly-very painful), strange rashes, low sex drive (high libido prior to receiving the shot) body aches, headaches, emotional swings, irregular bleeding, varicose veins, headaches, dizzy spells, nausea, blurry vision, and visually noticed loss of muscle tone. I gained 25 lbs. in a period of approx. two months despite my already extremely healthy dietary intake (I eat virtually no sugar, no artificial sweeteners, consume very few refined carbs, drink only purified water (no caffeine, no sodas, no juice, no aides), eat plenty of organic veg F 38 1 years
8/24/2007
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 4  good but minor side effects ITS GREAT, But some lower stomach pain. feels like light cramps but no period, no weight gain!! some acne? dizziness? ive been on the shot for almost a month now and i like it. i have ADHD and take adderall xr, and because i take adderall xr it can cause serious damage to my baby if i get pregnant while taking my medication. the adderall xr decreases my apitite and the shot can increase it so i think the adderall xr balances me out. so i havnt gained weight but if i dont take my adderall xr i can eat all day!now about the shot! good sex, normal sex drive and maybe increased sex drive. some leg pain but it might not be from the shot it could be growing pains considering im young. im still worried about the 3 out of 100 pregnancies, i dont wanna be one of the 3. i love not having to worry about your period and getting pregnant. and ive gotten a little more acne on my face since ive been on the shot. but it could also be teen age acne kicking in.. im worried about the brittle bones though so if i get symptoms i will get checked.. F 15 1 months
8/22/2007
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 4  to not get pregnant. i've had some pretty weird side affects from this. none really bad. but none really "normal" either. i've had a HUGE change in appetite.. and used to LOVE greasy, junk food. but now i love fruits and vegetables! it's great! i've also had in increase in sense of smell. this isn't too bad, but i start to feel sick because of it sometimes. i know you're probably thinking that "she's pregnant" but im not. it's really not too bad and i recommend it. everyone says not to take depo because of weight gain and stuff. well maybe it's because of my age, and i might not want to take it for the rest of my life, but it's worked so far. i'm happy with it. F 16 6 months
8/21/2007
 1  Birth Control Patchy rash all over arms and legs, migrains, extreme mood changes, depression, hair loss..the list goes on and on Don't touch it!!! Doctors are giving out the wrong information. They don't believe there's a problem, but there are so many of us with the same symptoms..so why not? If anyone has any idea on how long the rash takes to disapear please advise? F 24 1 times
8/21/2007
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 1  Birth Control My doctor wouldn't put me on the Pill for heart reasons, I've had only the 1st shot and I am going crazy, I can't stop bleeding I constantly yell and fight with my boyfriend, I am eating every 5 minutes, I'm paranoid about stupid things. I use to be the life of the party and now I sit home thinking everything is horrible. I can't have sex without bleeding. Its absolutley ridiculous!!! I hate it. I can't explain the way my body feels sometimes! I ache and feel crappy! If you are looking at getting on DEPO I recommend you read all these comments and side affects and then make a decision!!! F 21 3 months
8/20/2007
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 4  very painful periods Depression, some weight gain, NO sex drive, very low energy, tired all the time, lack of motivation. It has been good to me. I suffered from very painful periods and the side effects of the bad periods were worse to me then the depo side effects so far. With my period i was extremely depressed, couldn't go to work or have sex because of the pain, and wasnt able to eat, had absolutely no energy, horrible headaches and periods that would last sometimes for months. In a ways depo has been a relief, but the possible side effects worry me to death like osteoperosis, and long term effects. I have less energy since i am taking depo, and may have early stages of osteoperosis, i just have to be careful and take extra calcium. Its a matter of weighing the effects of your period vs. depo. Please do not get me wrong i still wish there was another alternative. F 26 2 years
8/19/2007
 1  prevent pregnancy Within the first two weeks of taking the shot, it caused anxiety and caused my temper to become very bad. I get very short tempered at the littlest things. I have absolutely no sex drive!! I have no period. My husband dont want to be around me sometimes because I get on to him about really stupid stuff, and my daughter gets in trouble for just being a kid. I hate these side effects.I used to be a really calm and nice person. I've been taking the shot for 2 years. If you have these side effects DONT take the depo shot!! F 23 2 years
8/19/2007
 1   For birth control//and to have no periods I only took the shot for 3 months and it was the worst three months of my life. All my friends completely lost their periods, I had mine 3 weeks out of every month. Now that I have stopped taking it, my period won't stop. It's been 34 days of hell so far...when will it stop? F 3 months
8/18/2007

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