DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Prevent Pregnancy Just spotting the first 4 months so far. A little lack of sex drive too (but also because I have no bf and my last bf had sexual issues himself so we rarely had sex even when I tried to initate every time)! I've tried the patch, nuvaring, and depo and so far I like the depo shot. The patch was way too strong for my small body and the nuvaring kept sliding down so much it was uncomfortable. The depo, I don't have to worry about swallowing a pill every day, put a patch on every week or the ring every month. I am going to wait for the full 9 months before deciding what to do about it. I do take calcium supplements every day and try drinking milk as much as possible too since I have a small body frame. I will try to remember to go back on the site at the end of 9 months to let y'all know if my opinion has changed or not. F 26 4 months
6/11/2009
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 1  endometriosis pins and needles in my legs; extreme moodiness and some depression. Very poor sex drive and depo is not helping with the endometriosis pain. Doctor had recommended this due to my recent diagnosis of high blood pressure. On Pfizer's own site (about 4 months ago) they had a warning about depo provera stating that no one should take this BC for more than 2 years due to the severe osteoporosis that is coming to light for users who used it more than 2 years. This concerned me since my doctor never gave me any printed information about side effects (that's why I was on the official site-- to find out if my side effects were caused by the medication). That part of the site is no longer accessible, so I wonder if Pfizer is circling its wagons, so to speak (maybe litagation is starting to happen??). I will not be receiving my 3rd shot in July. F 36 6 months
6/10/2009
 2  to manage heavy periods constant spotting is my main issue...i have a fibroid that has caused heavy periods....tried to have it removed and the doctor ended up damaging my colon!! supposedly my only alternative is to have a hysterectomy but I've been told that I will most likely have more damage done to my colon due to adheasions from the first surgery. My doc recommended trying depo for a year to try and stop my periods....so far it has not worked. I am trying to hang in there for a full year to see if my periods will eventually stop otherwise I guess I'll be bleeding until i hit menopause. Hearing so many terrible stories about depo is scary but I'm hoping that things will eventually settle down since there do seem to be some people that do well on it. As far as other side effects go, I do have depression and lots of anxiety but I had that before I started depo so I'm not sure I can completely blame it on the shot. F 40 8 months
6/9/2009
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 1  BC Amenorrhea, Depression, Anxiety, Paranoia, Moodswings, Weight Gain (more than 10 lbs.), Hot Flashes, Headaches & Migrains, Sharp Leg Cramps, Hair Growth (in undesirable places!), Complete loss of Sex Drive I know everyone's body is different but I would definitely use Depo as a last resort! I didn't have a period for more that a year after I stopped taking it and then I would get one every 4 months. Also it is known do increase bone density loss, NO GOOD!! I took it because I am not good at remembering to take a pill......I would not recommend this form of BC to my worst enemy, esspecially not a young girl whose bones are still growing! Users BEWARE! F 20 1 years
6/9/2009
 1  didnt want to take the pill No sex drive,breast milk and periods last months some times. Don't listen to your doctors.They tell you it will straighten put in a couple months.BS.It just got worse. Heavy periods,breast milk showed up and now theres lumps in my breasts.I'm tired all the time no sex drive have no desire to do anything. I just feel like a bag of crap.The pill is the way to go. F 16 2 years
6/8/2009
 1  birth control no period followed by double period, migraines, bad mood swings I was on the shot about 15 years ago. I had no problem and no period for the whole summer. I decided to try it again. I had talked to my FP doctor because I have bad migraines (that put in the hospital for 4 day at a time) and very heavy periods every month. We decided that the benefits might help. Were we wrong. I was in the ER this weekend because I felt like I was in labor (I have had 2 babies) and bleeding heavy. They told me it was a double period and that I should contact my OB/GYN. I have had a migrain for 3 weeks now. I just got out of the hospital Thursday. I have been take percocets like crazy just so I'm not in pain. I'm also taking meds for the nausea. I feel like I'm pregnant. I know I'm not because I have had blood work done. I will never use the shot again. I also hope I don't bleed and feel sick for the next month while the shot expires! F 28 53 days
6/8/2009
 3  Birth Control severe cramps, no period, regular migrains, anxiety which effects my increase in sex, depression i feel like crying all the time over simple things. Irritation, fatigue, constant hunger. F 18 3 months
6/7/2009
 3  birth control extreme anxiety (i already was dealing with this but it made it worse), moodiness, constant bleeding after the first month After reading everyone's comments and side-effects, I really should not have started taking this. It had made all my previous problems (depression, anxiety) worse and a loss of sexual desire. I dont know how my bones have been or will be affected but this is the only dose i will be taking! F 17 1.5 months
6/6/2009
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 1  prevent pregnancy Breaking out, mood swings, so tired almost like im pregnant again I havent been on it for very long but it just feels like I am going to start my period, (but I just got off of my period and it isn't suppose to come until the 21st) by my mood swings and tiredness. My boyfriend asked me yesterday if I was moody it seems like I just want to jump down his throat. I feel bloated all day long and I just want to sleep but I cant and I trying not to get mad at my 11 month old son. F 26 10 days
6/5/2009
 2  birth control CONSTANT BLEEDING, huge mood swings, rage, anxiety, lack of and no sex drive, vaginal dryness, sharp pains during sex, sharp abdominal pains, slight weight gain and constantly hungry, slight depression The depo shot was my very first form of birth control. I didn't want to have to remember the pill everyday and a few of my friends had been on it for a while with nothing but positive results minus a slight weight gain. I have always been an athlete so the weight gain did not effect me very much except an increased appetite. I only took one shot and decided not to do it again. A few weeks after getting the shot I had vaginal dryness and there were sharp pains any time I had sex. After discontinuing the treatment I have such extreme mood swings, and even fits of rage. While on Depo I only had one period and had such sharp pains in my lower abdomin. I went the restroom to have my uterine wall fall out! My boyfriend took me to the ER right away and they explained it was nothing serious, just my body getting used to the drug since I had had no period for 2 months. I HAVE CONSTANT BLEEDING since I stopped the shot and the heaviness varies. I still have a lack of sex drive and since I bleed all the time don't even want to get intimate with my boyfriend! The whole thing is nothing but draining and annoying. F 19 3 months
6/4/2009
 1  to protect from pregnacy . horrible anxiety, hard to consentrate, sensitvity to light, head ache, joint pain, probable bone loss, heavey bleeding, bloting, hunger,hair loss, anger, depression, crying, fatigue, dryness, loss of sex drive,vaginal, dryness, breast lactating, muscle pain,pain at enjection site, large indention on hip, pvcs, cheast pain. theres a detox that helps but causes to bleed for like two mo. GNC store Complete cleanse! helps... F 26 3 years
6/4/2009
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 1  Birth Control Spotting the first two weeks or so, moodiness, fatigue, weight gain, and now that I'm off it, a period that's lasted about a month and a half I seriously regret getting this shot. I have no history of depression nor does my family, but the first month I was on it, I felt so depressed. I cried all the time, and I got so cranky at people for no reason. That fortunately did let up, but I gained about 40 pounds in 3 months from this damn shot. I exercised, I ate right, and I still gained weight, which is extremely depressing, especially this time of year. I can't fit into any of my old clothes, I can't wear my bikinis because I have awful stretch marks on my tummy and hips, and I feel like crying every time I look in the mirror or see pictures of myself when I had a nice figure. I knew weight gain was a side-effect, but I was told that if I exercised and maintained a healthy diet I would be fine. Well, I wasn't and for the first time ever, I hate my body. Thanks Depo-Provera! F 22 120 days
6/3/2009
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 3  Effective Contraception migraines, weight gain, increased appetite, depression, anxiety, crying very easily, severe pain during sex, chest/heart pain, leg cramps, no period (not even spotting), anger, irritability I've been on the Depo shot for about a year now, and although it's been great because I'm not pregnant, the depression and pain during sex can be pretty annoying. I haven't experienced a loss of sex drive and an currently taking calcium citrate supplements (recommended by my doctor due to me being on the Depo) but with hearing all these bad experiences people have been having with it, I'm not sure if I want to stay on it. I have pretty much no friends anymore other than my boyfriend, and am very irritable with everyone who tries to talk to me or anything that happens. F 16 1 years
6/2/2009
 3  Birth Control I did not receive a period for the duration I was on Depo. I started Depo in May 2001 and my very last injection "expired" on October 11, 2008. I did not receive a period this entire time, which I really enjoyed. I discontinued this med because I felt like I was bipolar on it. My mood swings were TERRIBLE. Now that I've been off if it for 8 months, my period still has not returned. I feel better (mood wise) but I still feel terribly abnormal because it's taking so long to get my period back. I'm now starting Aygestin to induce a period. Keeping my fingers crossed that depo didn't screw me up for good. F 29 6.5 years
6/1/2009
 2   No Period for two months then I have a period for a month, weight gain, fatigue, muscle soreness, vaginal dryness during sex I originally thought this would be great because I wouldn't have to worry about taking a pill. It gives me light long periods. I bleed for like a month till I get my next shot then it stops for two months. I've been eating right and excercising and still can't seem to lose weight. Not ideal for me at all. All together I have taken it for a year but with a break and a pregnancy in between. F 22 1 years
6/1/2009
 1  Birth Control * Gained 40 pounds (felt like the weight gain happened overnight!) * Severe depression (crying for no reason on a weekly basis). * Felt soooooo exhausted and tired ALL the time. * Constant bleeding (4 solid months without a break!), ended up having to have a D&C to stop the bleeding. * A blood clot formed in my left leg and ended up in the emergency room with a left leg that was cold and white because blood had stopped flowing to it. Luckily, emergency surgery prevented me from having my leg amputated! I only took 3 shots of this medicine (poison) and it took me almost 10 years to recover from what this stuff did to my body! It was so terrible. I wish I had looked it up on the net before I ever had the first shot. I would have NEVER allowed that stupid doctor to "try it" on me! Lesson learned. This site was a great idea. F 39 3 times
6/1/2009
 4  to prevent painful, heavy periods It was fine at first, didnt really see much of a change but recently I have been extremely bloated and Iv been feeling sick when I eat, also my breasts have gone up 2 cup sizes and I have put a stone on since I started on it. Although it is very helpful because I have a long-term serous boyfriend, I am starting to get a bit fed up of feelig like rubbish. F 19 1 years
5/31/2009
 1  birth control severe weight gain, decreased sex drive, hypothyroidism, chronic yeast infection, dryness and vaginal irritation, pain with sexual intercourse, very irregular periods I took depo for aprox 5 years which was the biggest mistake of my life. I continue to have sig. problems after stopping this shot. I have not been able to get rid of chronic yeast infections and dryness in the vaginal area since being on the shot. I also continue to have significant pain with intercourse. I now have multiple folicular systs and am having difficulty trying to become pregnant. My weight gain due to the shot has also caused multiple problems. Overall this has been a very nasty drug and has caused multiple ongoing problems even though I have been off of the shot for almost 5 years now. Would like to know if there is a class action suite being persued against this drug. F 31 5 years
5/31/2009
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 1  effective birth control loss of sex drive, painful sex, prolonged bleeding, vaginal dryness, muscle soreness and cramps I started taking the shot right after having my daughter 10 months ago. I thought that the vaginal dryness and pain during intercourse was just from childbirth but now I am finding out that depo seems to cause it. I bled for the first 6 months after giving birth NONSTOP! And now it has gone away but two days ago I started experiencing this terrible muscle soreness in my arms and legs and it won't go away. It feels as if I ran a marathon but I have not done any exercise out of the ordinary. Does anyone know if this is a side effect of depo? Please, if anyone has had a similar experience with the muscle pain, email me. I am really beginning to worry that something is terribly wrong.DON'T GET THIS SHOT! The doctors don't tell you about these side effects. F 20 10 months
5/30/2009
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 4  Birth Control Not sure that any of my symptoms are from depo or not. I have been on it twice. The first time I had no symptoms at all. Now I do have some of the listed side effects but am not sure if they are related or not since I didn't have any when on it before. I have collectively been on depo for about 5 years. I tried other forms of birth control first but found them to be innefective. I started on the pill and became pregnant. After the birth of my son I had an IUD, about a year after I had the IUD placed I became pregnant again. This was very scary as they had to remove the IUD once I became pregnant which has a whole slew of side effects in itself and can cause miscarriage. So after the birth of my second child I opted to go on depo. I didn't gain any weight, I had no side effects at all. I did have irregular, and sometimes seemingly non stop periods for the first 3 months. By the time I received my second shot my periods had become less frequent and much lighter, only getting it about 4 times a year, and it was so light it was difficult to even use tampons. My husband and I decided we wanted another child (#3) so I stopped taking the shot. It took over year for me to get pregnant after I stopped the shot, but we also were not timing it, or taking temperatures, or anything like that. We decided we'd stop the birth control and then it would happen when it happened. So that may have contributed to why it took so long to get pregnant. I was completely fine after stopping the shot and had no adverse effects, headaches, depression, mood swings. None of that. My third child is now 9 months old. At my 6 week appointment after her birth I opted to go back on the shot. I had a very pleasing experience with it previously. Since about 3 F 35 5 years
5/29/2009
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