DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibroids immediate forgetfulness, irrational thinking, depression, fatigue, explosive anger, mood swings, blurred vision, dizziness, constant bleeding and menopause I will NEVER, recommend this drug! It's terrible, and it should be taken off the market! I feel that additional medical research will not improve this drug! I got my first shot in January 14, 2010. An hour later, I was forgetful, paranoid, anxious & confused. I skipped my menses that month. In February, I started to spot, this then increased, bleeding more throughout the months. There were times when I passed very large dark red blood clots. I visited my doctor and explained my symptoms, as well as my altered state of mind. I asked him if there was something that he could prescribed to stop the bleeding and to counter act the drug to get it out of my system. He replied I would need a "D"- for some reason, he didn't complete the last part of his sentence, he was going to say a D & C. He changed direction and said that I would need to take another shot. I told him there was no way that I would take another shot and how in the hell could he have the audacity to recommend that I take the shot again even after I've told him what I'm been going through. He called me later on that night (feeling guilty) to check on me, he said "I don't blame you for not wanting to take another shot." I feel extreme anger, I have a drug in my system that has to wear out. April 15 - 25th I had a very heavy menstral with large dark clots. From April 26th - 29 nothing, now today, the 30th I went to the restroom and noiticed that I'm starting to spot. Well, I thought all F 49 3 months
30 mg 1X M
4/30/2010
 1  Birthcontrol severe mood swings, deppression, eczema, severe headaches, from no periods while on the shot to constant periods for 6 months after getting off shot, crying uncontrollably over nothing. I had too many side effects to count. I have always had dry skin, but on this shot I developed series eczema where my legs would start bleeding becuase I would itch them so much in my sleep. I honestly became a crazy person with the constant mood swings and would get so angy over the tiniest things that I would just have to grind my teeth to keep from screaming I was so mad, and I have always been an easy going, laid back person before the shot. I hated who I was becoming. I also gained about 40 pounds in 6 months and coulnd't control it no matter how much I worked out or dieted. I am still struggling with the weight and I have been off the shot for over a year. I would NEVER recommend this shot to anyone and STRONGLY urge anyone to get off of it as soon as possible. I don't understand how this shot can be legal. Also the doctors where I got this shot didn't warn me of any of the side effects which isn't right! They said that there weren't any more side effects with the depo than any other birth control which is NOT TRUE!!!! This is the devil's drug. F 21 3 months
3 shots 3X O
4/30/2010
 1  Painful periods Breast tenderness,fatigue,fluid retention,sadness,unable to lose weight-but i havnt put any on either while being on depo which people say they have done,aching limbs,light period 24/7 since the day of 1st and last of the injection I wanted to have the depo provera injection because for many years now i have been having extreme pain with my periods and,because i have had M.E,(chronic fatigue syndrome)it made the pmt a million times worse and i was bed bound with no energy and looked as white as a ghost.So i thought this would help me.I DID i must say look at this forum and i read all the horror stories and comments so i knew the side effects and knew what i was letting myself in for.But i thought,i might be the lucky one and everything will be fine-NO.I had my first jab 31 days ago and,even though things were ok to start with during the 1st week,things went down hill from then on.Id been healthy eating and exercising prior to the injection and had lost 9 pounds.Yay.But the week after the jab id put it all back on again which f****d me off so much.Then i started to have no energy to carry on with my exercising,which after 9 years of M.E and finally recovering from it and getting my life back to normal and getting my energy back,the energy was zapped again.So anyway,as the next few weeks went by,my period has been on and hasnt stopped-light spotting constantly.The thing that i really hate about depo is just how its making me feel.Losing all my energy again.Ive had my fair share of that to last me a life time and i want it back.I havnt put on any weight since the injection but i havnt lost any either.I feel massive though and it is just because of the fluid retention i know but it doesnt make me feel any b F 32 31 days
1X O
4/28/2010
 1   depression, anxiety, mood swings, tired all the time, and very emotional after i had my second child in 05 i started taking the shot and was terrified that if i got off i would become pregnant again so i took it for 2and a half years and i and no period and was very deperessed and i gained about 60 pounds over this time when ever i heard about the i.u.d. i got that done and 2 years later after having problems with that also i started taking the shot again and now i remeber why i stopped taking it in the first place! but i am terrified of getting pregnant again. and of course my husband doesnt understand why i have been so moody and sad lately. F 22 2 years
1X day
4/28/2010
 1  birth control no period for three years, vaginal tissue was destroyed, initial penetration was enough to put me in tears and tear me inside, frustration I was on depo for three years. my sex drive gradually decreased during this time. Also, sex started to become painful. It ended up so bad that I would be torn inside after anything went in there. My last shot was due in July of '09. I decided not to take it, thinking it might be the lack of periods causing it. My OB took one look inside and said my vagina looks post-menopausal. I am 26. He prescribed estrogen and it helped a little initially, and then it stopped helping. The thought of sex puts me in tears. I'm a newly wed and cant enjoy it because of this nasty piece of medicine. I still haven't had a normal period and we wanted to try for a baby soon... I have an appt. with the OB (6th one since quitting depo...) on thursday. I'm going to request the pill to see if it will kick start me into a regular cycle, which would hopefully mean more natural estrogen to aid my poor vag at least. F 26 3 years
1X O
4/27/2010
Email
 1  Birth Control Anxiety (paranoid), depression, mood swings I started taking the depot shot when I was a teenager. I have been off and on the drug since. Though it is worth mentioning that I have only been off it a total of 2 years in the entire ten years I used it. The first time I went off it it took about 4 months for my period to come back. It was only slightly more uncomfortable than I remember. However, I am now in my late 20s and I know that I need to take better care of my body if I want to have babies some day, so I have been off the shot since August 2009. Mind you, this is when I would have been due for my next shot. It is now going into May 2010 and I still have not had a period. I fear that I may have done damage to my fertility! This drug should be marketed as a short term solution not a long term method of birth control. No one should be on this for more than six months. I am relieved to know that I am not alone. As women we should speak out against these horrible drugs. I thought I was the only one with anxiety and depression from birth control. It's the big elephant in the room! Remember when post partum depression wasn't a common conversation topic? Now it's common knowledge! Let's bring these issues to the forefront of our health care! If we don't we will continue to suffer in silence. F 26 10 years
1X AN
4/26/2010
 2  Birth Control HAIR LOSS, loss of libido, spotting, sore/tight joints. I had no side effects during the first shot, but I got the second shot and my hair has been falling out like crazy. I've read that this could be a side effect for high androgen birth control options. I'm sure my lost hair will grow back eventually, but I do not want to take the chance in getting a 3rd shot for fear my hair will continue to fall out. Birth control is so frustrating, I feel like I can't find a side-effect free option for me! F 24 5 months
2X O
4/23/2010
 5  easier than remembering the pill The depo shot was great while i was on it and i got my last shot 3 months ago and now ive got all of these strange and to be honest scary side effects: dizziness blured vision. Extreme hot flashes. and just feeling over all weird. Has Anyone else experienced these symptoms after GETTING OFF depo F 20 5 years
1X M
4/19/2010
Email
 1  To prevent pregnancy After recieving the shot, I became very depressed. I have no sex drive at all, and I cannot get aroused. Me and my boyfriend had been together for a year before I got the shot and our relationship was great, not perfect but pretty close. And now we aren't together because of how depressed I am. I get mad at him for absolutely nothing. I feel justified in the moment but then when I think about it later I realize how irrational it was. I've completely stopped hanging out with friends I used to hang out with on a daily basis, I sleep every chance I get because I am so incredibly tired all the time. I've hadsevere back and knee pain. I never really thought that the shot was the cause of these problems, but after reading all the stories about the negative side effects I'm pretty sure depo has caused these issues. The one good thing about depo is that it does prevent pregnancy. A birth control that lowers your sex drive, whats the point in that? Me and my ex used to sleep together everyother F 18 7 months
1X day
4/18/2010
 4  so i wont become pregnant M 16 3 months
1X O
4/16/2010
 1  Birth control Moodiness, anxiety, back pain, exhaustion, fatigue, etc I just finished my first three months of the shot and will NOT do this again. I am a very upbeat happy person and lately all i do is cry and have extreme anxiety. This shot has effected my job, and more importantly my relationship with my boyfriend who thinks i'm a crazy moody person nowadays. I do not recommend this shot. I can't wait for it to leave my system. F 18 3 months
1X AN
4/14/2010
 1  Contraception Bleeding almost constantly since about 2 weeks after my first injection, sometimes quite heavily and with bad cramps. Anxiety, depression, moodiness, tearfulness, almost felt hysterical at times - this has caused me to have to take time off work as I felt incapable of doing my job when I would burst into tears for no reason, and I've felt lower than I ever have, but haven't been able to put it down to anything going on in my life. Do not have this poison injected into you! I had my first jab in December 2009, after trying a few different forms of the pill and finding that none of them agreed with me (either tearfulness/anxiety or bleeding before I finished the pack). I had previously had Depo when I was 18 or 19, and found that it stopped my periods, but was hell when I came off it. I bled pretty much solid for six months when I stopped it the last time I tried it. This time, I knew I wanted contraception for a few years and knew my experiences of coming off it wouldn't happen again for quite some time, so I decided to try Depo again. How wrong was I?! I started bleeding a couple of weeks after my first jab four months ago and haven't stopped apart from maybe 2 weeks during that time. Emotionally I've gone through hell too, feeling like I was cracking up and unable to go to work for a couple of days because I felt so hysterical one minute and so low the next. I can't wait for this to get out of my system; I've read it will take at least 6 months. There is no way of getting it out of your system any quicker, it's not reversible if your experience of depo is as hellish as mine. Think very carefully about having this, even if a previous experience of Depo was okay, it seems it affects your body differently as you age, as well as it affecting different people in different ways. F 27 4 months
1X AN
4/11/2010
Email
 4  didn't want a baby or a period no period, no craps, no mood swings On depo for 15 years… after about 2 years no more periods, no craps, no mood swings…loved it. I have gained some weight over the years but that is due to my diet and can’t blame that on the drug. I’m 5’6 started when I was 18 and weighed 120 now I’m 145. My doctor was concerned about my bone density. Had it tested last month and it was normal but due to the fact I just had a birthday and have considered the fact I might want to have a baby someday I did not get my last shot which was due March 16,2010 about a week after my shot was due started getting hot flashes and felt totally blaaaaa. The hot flashes are gone I just got some very light spotting no craps yet but have a serious lose of energy. I normally go 2 the gym 4-5 times a week and find it hard 2 drag myself there 2 plus times. I still walk my dog 3 times a day but really wanted some helpful information on how to help my body detox faster. The sooner I can get this drug totally or as much as possible out of my system and get back to my energetic self. There is a down side to everything and at 18 I could not see that thought it was the wonder drug. Now I’m not 2 sure. F 33 15 years
1X O
4/9/2010
 1  contaceptive excessive weight gain and hunger camparable to pregnancy I have been off the shot now for four months and have not been able to lose the weight no matter how often i work out. I gained 18 pounds on the shot in a matter 4 months and still am steadily gaining weight since the side affects are known to last up to six months after coming off. I DO NOT RECOMMEND THIS SHOT TO ANYONE! I was always thin with a high metabolism but this shot has ruined my figure. please do not ever take this medication. F 24 4 months
30mg 1X O
4/7/2010
 5  Couldnt remember to take the pill PMS like symptoms and some spotting right before it is time for my next shot. I dont have a period other than the occational spotting every couple of months. Depo was my first birth control and it has been great. I have never been one to remember to take a pill every day so once every 3 months is perfect for me. I cannot say any weight gain or other sypmtoms are caused by the depo.. they could be from me being a piggy! I stopped taking the depo and had my son and then started again right after I was done breast feeding. I plan to have another child again in the next few years and continue the shot. I think it's great and wonderful! F 25 7 years
1X AN
4/6/2010
 1  birth control depression, anxiety, mood swings, headaches, frequent bleeding, hot flashes, blurry vision, reduce sex drive i've only tooken 2 shots so far; and i will not be back for my third. id rather take my pills everyday; than get this shot. after taking this shot; i quickly spiraled down into a deep depression. i went to a counselor, and she told me to do research on depo; and that my depression could be related to the shot, and most definitely, i see that now, i am not the only one suffering. i hate this shot, wouldnt recommend it. ive continued to bleed, doctor telling me, it just takes time, but i hate it. im cleaning it out of my system, this shot really brought me down, and i feel almost every side effect. i believe there should be more research done on this shot. F 20
1X day
4/6/2010
 1  couldnt remember to take the pill depression, severe stomach aches, very frequent vomiting and diarrhea, numbness in hands, severe nerve damage causing severe arm, hand and wrist pain, massive weight gain(while throwing up and having diarrhea constantly, riddle me that batman) , sluggish, always tired, incapacitating headaches, moodiness, really bad paranoia, bone loss, easily broken bone, joint pain, thyroid condition............. I could not figure out how I had turned into this angry person who hated myself, and everyone else, I am still trying to battle the depression, I hate looking in the mirror, I cannot lose the weight, I hate being around people when I used to thrive around others. I am ridiculously paranoid about everything when I used to be care free. I am losing the ability to use my hands for more than 5 minutes, then they go numb, and once the feeling comes back there is enormous pain that goes from my shoulder to the tips of my fingers. I cannot grip things tightly at all, and cannot open jars etc. I have a hard time holding my 2 year old for more than a minute at best. I didnt get my shot last month and am trying to flush it out of my system, still havent gotten a period, but I guess that is normal till the 3rd month of not having the shot. I am just hoping that I can get treated for the damage it has caused me and I hope people do what I was too stupid to do, and actually read about what this thing can do to you before they get it. Its a poison in my mind, and I wish I had never taken it. I have such a mess to deal with, and I just hope that I can go back to the way I was, and like myself again once I get my body back....... F 22 592 days
1X AN
4/5/2010
 1  Birth Control Weight gain, vaginal dryness, no sex drive, painful intercourse, bleeding after intercourse, irregular bleeding and spotting, intense cramping after orgasm, random irregular bouts of severe cramping, tiredness all the time, lack of energy or interest in anything, hair loss, bloating, IBS, frequent urination, emotional and moody, paranoid, depression, anxiety, sore boobs, bloating and gas, joints and muscles ache, occasional headaches, bad acne, anger problems, and possibly other things I haven't noticed yet. I have been on the Depo since I was 18 and was not informed of any of the side effects at all. Most of the side effects I have experienced didn't start up until a few years after I first started taking it. I'm tired of being in constant pain and discomfort and did not continue with my current shot. I instead started on Lybrel bc pill which is the first and only no period pill. I love not having a period and can and will deal with occasional spotting but hope all of my other bad symptoms will go away. Please research before going on the shot it's horrible and I fear will take forever to leave my system. I have also heard that the shot can make women more susceptible to STD's so be careful, also of the bone loss issue. F 25 7 years
4x a year 4X O
4/5/2010
Email
 2  18yrs old. I did not want children NO PERIODS(WHICH WAS REALLY NICE). NEGATIVES: STEADY WEIGHT GAIN, DEPRESSION, ANXIETY, IRRATIONAL BEHAVIOR, VERY SHORT TEMPERED, OVERLY AGGRESSIVE, BLOATING, WATER RETENTION, GASTRO-INTESTINAL ISSUES. DURING THE 15 YRS ON DEPO I BLAMED MY SIDE EFFECTS ON EVERYTHING BUT THE DEPO,I NOW KNOW THAT I WAS IN DENIAL. I SOUGHT HELP FOR DEPRESSION & ANXIETY WITH MEDICATION & IT DIDN'T HELP. NOW THAT I'VE STOPPED, I REALIZE HOW MUCH THE DRUG AFFECTED ME. 15 YRS ON DEPO. I'VE BEEN OFF OF IT SINCE 8/08. I'M NOW HAVING PERIODS EVERY 14-16 DAYS FOR 6 DAYS. I NO LONGER HAVE THE ANXIETY AND DEPRESSION PROBLEMS I HAD, I FEEL MUCH MORE NORMAL AND RATIONAL I DON'T 'FLY OFF THE HANDLE' FOR SILLY REASONS. I HAVE YET TO LOSE THE WEIGHT THAT I GAINED WHILE ON DEPO. ONE OF MY FIRST UNDENYABLE CLUES THAT DEPO WAS THE ISSUE, WAS WHEN I STARTED GOING TO THE GYM AND WORKING OUT 2HRS A DAY 5 DAYS A WEEK FOR 6 MONTHS WITH NO WEIGHT LOSS WHAT-SO-EVER! I LOST VERY MINIMAL INCHES NOTHING SIGNIFIGANT ENOUGH TO BEGIN TO JUSTIFY THE AMOUNT OF CALORIES I WAS BURNING!! I'M IN THE 'DETOX' STAGE OF THE PROCESS NOW, INITIALLY (1ST COUPLE OF MONTHS AFTER STOPPING)I HAD SEVERE CRAMPS & BREAST TENDERNESS, I BEGAN TO START FEELING MORE 'NORMAL' WITH LESS ANXIETY & DEPRESSION. I FEEL MORE 'NORMAL' AS EACH DAY GOES BY, MY PERIODS SEEM TO BE LIGHTENING A LITTLE THE BREAST TENDERNESS IS MINIMAL BEFORE MY CYCLE AND THE CRAMPS ARE BARELY NOTICEABLE. I'M SOON GOING TO GIVE THE EXERCISE ROUTINE ANOTHER TRY. I WILL LIKELY SEEK OUT THE HELP OF AN ENDOCRINOLOGIST TO FIND OUT WHAT MY BODY IS DOING.I HOPE TO HEAR FROM ANYONE WHO HAS GONE THRU THE 'DETOX' OF DEPO AFTER BEING ON IT FOR YEARS SO THAT I HAVE AN IDEA OF ANYTHING ELSE I MIGHT HAVE TO LOOK FORWARD TO. F 35 15 years
4X O
3/31/2010
Email
 1  birth control After a year and no periods. I began bleeding so bad I couldn't go out. (For fear of bleeding through my jeans.) At which time my ob/gyn recommended an endometrial ablation. Which meant more than likely no more children. So, a little over a year after the ablation I am being told I might need a partial hysterectomy. It seems the ablation can cause scarring resulting in pain. There is no way to stop bleeding like that from depo to my knowledge. I feel if I would have never taken depo then no ablation would have been needed which means no hysterectomy. I would strongly urge women to consider other options. Please note that I was breastfeeding while on depo because it appeared to be the safiest for my son. I only hope that he does not have any problems later. I feel it is unsafe for women and should be investigated further. F 36 1 years
4X O
3/31/2010

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