DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  endo and abnormal bleeding Morning sickness and early weight gain and long periods. I only got one shot because it is awful. Doctor told me irregular bleeding could be a side effect. 2 week long periods are quite annoying. Morning sickness and early weight gain, and people asking if I am pregnant. Have been coming off for 2 months and have gained more weight, more 2 week periods, no more sex drive or even opportunities with 2 week periods coming every 21 days. I was very fit, still eat better than most, but have to buy bigger clothes because of a lousy shot. F 35 3 months
1X O
9/22/2010
 4  to slow down/prevent heavy periods extreme weight gain, fatigue, migraines, swelling in the feet, back pains, complete loss of period I began getting depo shots when I was 12 to prevent my heavy bleeding. And for that it worked really well, this is the only reason why I chose to continue receiving the shots. I've always had headaches, but they became more frequent and more painful. My stomach was saying that I wasnt hungry but my mind was telling me to eat..I guess this is partially what caused the weight gain. I went from 160 to 217 over the past 4 years. Everytime I take a break from the shot, I won't bleed for months at a time and when I finally do, it lasts for about 2 or 3 months..I would only recommend this as a last resort for a solution to extreme heavy periods. Nothing more, nothing less.. F 18 6 years
1X day
9/21/2010
 3  Endometriosis Daily headaches, blurred vision, night sweats, mood swings, weight gain, and urinary frequency at night. Depo Provera was good in the sense that it got rid of my heavy periods and horrible pelvic pain, but I think I would prefer my endometriosis symptoms to the side effects from this medication. Especially bothersome is the blurred vision. F 35 3 months
1X O
9/21/2010
 1  prevent pregnancy Weight gain, bled for several weeks at a time, zero sex drive, sore breasts, acne Stay away from depo, this is not normal. I've never had to excercise to maintain my weight. I'm a waitress and I walk to work so I'm plenty active, and I haven't changed my diet at all, but I've still managed to gain 30 pounds in 6 months. I bled for 5 weeks until I got my second shot. All was well until I started bleeding again, also for 5 weeks until it stopped on its own. I decided that's enough so didn't get another shot, and have now been bleeding for 7 weeks with no end in sight. I usually love sex, but now feel unattractive from the weight gain and it's considerably less enjoyable. F 25 6 months
1 shot 1X O
9/18/2010
 1  Birth Control I took the depo shot for a year. After stopping the depo I continued my daily work outs and ate my healthy foods and managed to gain 87 lbs in 6 months... Crazy huh? Then whenmy husband and I decided to get pregnant we tried for about 16 months and had no success so because he is diabetic we thought he was having problems so we got him tested and all was fine then I found out that I have PCOS caused by the depo and now have been on fertility for 3 years and cant get pregnant. Please dont take this shot. F 21 1 years
1X O
9/16/2010
Email
 3  Pregnancy prevention Non-stop bleeding, breast tenderness, mood swings I took the shot for the first time in May 2010, the first 2 weeks I was an emotional wreck, but just as soon as those symptoms came, they left, never to return again. In that 2nd week I began to bleed, and it was more than just spotting. It was thick and dark brownish in color, to the point that I had to wear tampons almost every day for the entire 1st 3 months. I suffered terrible migraines and cramps during my periods prior to getting the shot and havent had any problems since. Thank goodness. I do not miss those at all. My breast continued to be sore on and off again over the whole 3 months, but other than the constant bleeding I don't have a problem with the shot. I have experienced a decrease in appetite and actually lost 12 lbs in the first 3 months. Was going to change methods this time but heard that the bleeding can get better after the first one is over. We'll see. I just got it today. If it doesn't get better and I dont stop bleeding, then I will switch. Rather have my period one week a month than every week of every month. Did not get depressed, gain weight, develop acne, have mood swings, night sweats, low sex drive, or any other symptoms listed on here...just the bleeding. I guess I'll find out what the next 3 months have in store for me. It would be perfect if I would just stop bleeding!! F 32 3 months
1X AN
9/14/2010
 1  Birth Control Absolutely No Periods, Fatigue, Hungry, some weight gain (mainly in mid- section), trouble sleeping, irritability, no energy at times, little to no sex drive. I have been on the Depo-Shot since I was 17 and in the 11th grade. Throughout my college years I, got the shot. Then I started to wonder why there was little to no more recent updated information on this drug. So I started to take a break from it because my doctor could not give me much more information on how safe it was to continue to stay on it as long as I have. In between my breaks, I would have terrible, excruciating, painful periods. They were so painful that I would have to stay in bed and cry because I was unable to move. Because of this pain, I would always return back to the shot to avoid this. In 2006, upon me graduating college, I stop the shot. I did not want to not have a back up birth control so my doctor put me on some BC pills. I started the pills as prescribed. I got so sick from the pills: sore breast where I could not put my arms down, could not sleep, I developed a rashy acne in the form of a beard on my face. From this, I had to start using Proactive and I have never had any skin problems in my life. I stopped the pills. I waited almost 6 months before I started the shot again. After the unbearable periods, I just could not bear it anymore. I started the shot again. Since this, I have been on the shot continuously. I finally decided again in May 2010, not to get the shot ever again because no one can give any answers on the prolonged safeness of this drug. After stopping the shot this past May I have not seen a period. No spotting or anything either. I F 28 10 years
1X AN
9/14/2010
Email
 1  Didnt have to remember taking a pill mood swings, nervousness, incresed apetite, weight gain, acne, no periods, spotting. Once off of it: bleeding for 20 days now, headaches, bloating, It was nice at the beginning, no periods just light spotting, and no pms, but once i was off it, i just started bleeding when i was supposed to get my period but ive been bleeding for 20 days now. its horrible, have been so tired, and its embarrasing and uncomfortable to have sex, so there is none of that. F 20 1 months
1X O
9/12/2010
 1  Birth control Extreme fatigue, moody, depressed, extreme night sweats, hungry all the time, dizziness/ light headed, I just started this type of birth control, I also have occasional night sweats from zoloft, but this is ridiculous. I have only been on this for a few weeks but it has not been good. Now I have to wait for it to wear off. Ugh. 1 shot every 3 mos. But I won't be getting another one. F 36 1 months
1 shot 1X O
9/12/2010
Email
 2  prevent pregnancy EXTREME fatigue, weight gain, always hungry, no sex drive, depressed mood. I think depo is good for preventing pregnancy and that's about it. I can best attribute the side effects of depo provera to the 1st trimester of pregnancy, expecially the constant fatigue. The only difference is the depressed mood that I feel on this drug. I have had one shot and I won't do this again. F 40 6 weeks
1X O
9/11/2010
 1  painful periods; prevent pregnacy; currently have fibroids cannot conceive headaches joint and bone problems, too many to list email me if you would like to discuss i am a pharmacy major and would like to help get it off the market. [email protected] F 21 1 years
? 1X O
9/11/2010
Email
 3  bad menstrual pain-birth control Mood change, aggressive, angry, sad. Spotting, would eat a lot, gained weight. Bad smell down there. It was good because i didn't have to worry about pregnancy and my menstrual pain def. went away. I decided to get off the shot because i didn't like the mood change and the weight gain. After getting off the shot (2 years later) i started to experience bad side effects. Nausea is the worst, i can't eat like before, i feel like puking sometimes. Bad pains when i get my period to the point that i can't move. Having trouble sleeping because i feel sick and my digestive system changed. I also got stretch marks on my thighs, also my breasts have been hurting sometimes. If anyone has had the same symptoms please e-mail me, i want to make sure i'm not the only one and that it is because of the shot. F 21 2 years
1X M
9/9/2010
Email
 1  prevent pregnancy Greasy skin and aggressive like a male. This changed my personality from mean to meaner. I'd fight with anyone any time a yelling match anywhere and my thinking was obsessive. F 26 2 years
10X AN
9/6/2010
 3  pregnancy prevention weight gain, bloating, abdominal pain, initial spotting, no sex drive, depression. F 31 13 weeks
150mg 1X day
9/3/2010
 2  prevent pregnancy Depression, dizziness, fatigued, weight gain, very heavy menstruation even after a year. I've been on my period for 2 months, and I have been getting the injections for a year now. I've decided to switch birth control methods. F 17 1 years
2 cc's 1X O
9/2/2010
 2  Endometriosis Headaches, ALOT of bleeding This is useless for endo, it worked for about 2 months and then stopped working, I dont recommend F 15 6 months
1X O
9/1/2010
 5  Migraines No period (a good thing!). No weight gain. PMS symptoms (sore breasts, slightly crampy, etc) when I'm due for a shot. Goes away within 24 hrs of receiving shot. I take one shot every 3 months. I started depo because I get migraines every month when I got my period. Migraines lasted 3 to 4 days and put me flat on my back. Depo takes away my period. No period, no migraine! I LOVE it! Nice not to have to plan around my monthly migraine! Can't wait for menopause! F 46 7 years
1X O
8/27/2010
 4  contraceptive The only thing I can contribute to this shot is a little weight gain... I get ravenously hungry the week before the time I would have usually had a period. I did this with bc pills, but NO where near this badly. I have NO periods or spotting with this shot, which is really nice! I haven't had any of the other side effects that most of the people have posted, but I also was already taking Lexapro for anxiety, so that might have helped me. Plus, my doc started me on a Vit D/D3, Calcium and Fish Oil regimen shortly after starting the shots, so that may be helping with the muscle/joint problems. Honestly, the side effects listed here are the ones I used to get with every kind of bc pill I used to take. I HATE bc pills and will NEVER go back on them... I think it all just adds up to your body chemistry and what works best for you. I think most women do best on some type of bc pill, I just wasn't one of them... but as bad as they made me feel, I wouldn't tell people to never take them... like I said it just depends on your body chemistry. Good luck to those of you who have had issues with the shot! I know how frustrated I was with the pill!!! F 35 90 days
once/3 mos 1X O
8/25/2010
Email
 4  Extremely painful and heavy periods For approx 1 week after getting injection i always feel very emotional, ie. cry easily, very tired, lacking energy and don't feel very socialable. These side aftes then start to wear off, thank God!! Occasionally get very light bleeding or spotting, which only lasts a day or two but with zero pain. No period at all for last 3 months. Have noticed some weight gain, even though i go to gym regularly. Must admit the week immediately after injection is pretty awful but still feel pro's outway the con's as i feel great for rest of the 3 months!!! Which is a miracle as i have been cursed with horrific periods since i was a teenager, but no more!!! Yipppeeee!!! :) F 35 9 months
4X O
8/22/2010
Email
 1  Fibroid cyst Nausea, increased appetite, hair loss, extreme exhaustion, dizziness, weight gain, acne and lower sex drive This is the drug from hell! In June my doctor game me a choice of either a surgery or taking Depo to treat my fibroid cyst. I didn't want to have surgery so I decided on the shot. I was told the main side effect/risk was blood clots. As you can see I have had many side effects over the last two and half months. My summer has been ruined and my fibroid cyst did not decrease in size. I have lost total trust in my doctor after going through this experience. My doctor told me that I was allergic to the drug and couldn't take another shot. Really? I wouldn't take another shot anyway! My side effects seem to be a common reaction to the drug, not an allergic reaction. I will never take another drug without doing my own research on it myself. So I am left with feeling terrible, still have a fibroid cyst and needing a new doctor. Let's wage our own war against this drug and tell everyone how bad it is! The few satisfied people on this medication are really a small percentage. F 48 3 months
1X AN
8/21/2010

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