DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Severe joint/muscle pain, stiffness, extreme irritability, psychotic depression, intrusive thoughts of suicide, mood swings, fatigue, constant bloating, random cramping throughout the day, complete loss of sex drive, vaginal dryness, painful intercourse (feels like there's a piece of broken glass stuck in there), mild but almost constant headache, anxiety attacks, rage I had never been on birth control before and I just decided to try it out. I have battled with severe depression and anxiety my entire life and come close to attempting suicide many times. 2 years ago I was diagnosed with schizoaffective disorder and I started taking the antidepressant Effexor. I've been taking 300mg/day since and I've felt wonderful UNTIL I GOT THIS SHOT. I feel like it's completely canceled out my antidepressants and I'm back to being angry and wanting to die all the time. The joint/muscle pain makes me feel like I've aged 40 years over night. F 30 3 weeks
12/3/2008
 1  birth control Nausea, non-stop bleeding I got the shot on Nov. 15 and it seemed as if my period was starting to go away, which is what I was hoping for. I just kept spotting and spotting for a couple weeks. Then I just started bleeding more and more. Now it's going back to spotting a tiny bit. Recently I've been nauseous and throwing up and have been having pregnancy-like symptoms. It's disgusting having sex. My boyfriend doesn't not want to have sex, so we do, and it's very messy and bloody. I can't take it much longer. I'm definitely not getting another shot. I'm too young to be destroying my body like this. F 20 18 days
12/3/2008
 3  BC DEPRESSION, dryness, lose of sex drive I feel like I've flown over the cuckoo's nest. I cry all the time and sometimes I can't even feel it coming, I knew that hormone therapy could make my a little moody. But this is unbearable. My boyfriends feels like it's his fault when I randomly start crying. I just can't get a grip on myself sometimes. I thought I was just stressed from school, but then I noticed I was in school longer than I've taking the Depo. Also, I got the Depo as a just in case Birth Control. I thought great, I can get one shot and be covered for three months and we can have our special night of romance when ever we're ready. No way on this stuff, I barely get wet anymore and I keep scaring my boyfriend with all this crying. I don't even feel like I want it anymore, I feel unattractive and blue. Finally, I took this drug because it was 'discret' BC, but how do I explain why I feel depressed and cry all the time? For future women taking this drug, do your homework, but don't afraid to try hormones are differen F 18 2 months
12/2/2008
 1  Heavy Bleeding WEIGHT GAIN, massive mood swings, hair growth I was on Depo because of fibroid tumors for approx 2 years. I highly do not recommend this drug. It provided me a 75 pound weight gain that I ams till trying to lose since 2003. My hormone levels are so out of control that I now seek assistance from a hormone specialist. My mood swings were ridiculous. I would yell, cry, scream for no reason at anyone. I have hair growth so extensive on my face and body now that laser treatment doesnt work for it. I can not stress enough how this drug makes your body a complete mess..it is TOXIC!!!!!! Please look into another way than this drug! F 34 2 years
12/2/2008
 1  cancer prevention, DR reccomended severe leg cramps, gained 50 pounds in 7 years, no amount of excersise will reduce my weight. My diet is so healthy I have had my annual blood work and my cholestorol was only 152! I have been acting weird lately too, I cry at the drop of a hat, or I will want to break the first toy I see on the floor just because it is in my way. I do not want to act like this towards my kids' belongings! I tell them to respect their things and yet I want to smash them.. talk about mixed signals! Until this last dose I have been what I concider emotionally balanced, although now that I think back and have been a cranky wench about a week after each dose hmmm, but by no means evil streaks or crying fits. connection? I don't know but I am not taking any more chances. I just thought my weight gain was due to aging, I never knew about all the side effects until this week when as a last resort to relieve the joint pain and muscle cramps I looked into maybe it being from Depo. I have read a lot about hypothyroidism in postings, is this a side effect too? I now have hypothyroidism and it is barely controled with meds (I am at the highest dose of 2 meds legaly prescribed) After reading this post site I will not be getting another shot right after x-mas. I love not having my monthly, but it is not worth my pain and suffering. No sex drive at all, nil, nada.In fact, I have not had sex in 7 years (how abnormal is that) just not interested enough to go out and find a good man after my low sex drive drove a wedge btween me and my boyfriend that could not be repaired, he thought I just didn't care about satisfying him any more. Women in my family have history of tumors and overian cysts, I was told that this med would greatly reduce that chance for me, my DR s F 33 7 years
12/1/2008
 1  birth control uncontrollable appetite, migraines, fatigue, mood swings I am going back to the pill in January. I've had two injections of Depo and while it's great to prevent pregnancy, it makes me an absolute mess. Find another birth control method. This one isn't worth it. F 19 4 months
12/1/2008
 1  Pregnancy Prevention headaches, HORRIBLE weight gain, NO sex drive, period for 5 months straight. I began getting the shot on my doctor's recommendation. Since the first day i got it seven months ago, I have had my period. Not just spotting. The worst is the horrible cramps! I never had cramps before going on the shot. I've been to my doctor and she told me my period would go away after the third shot. It didn't. In fact, It got worse. I will not be going back for my next shot and I would not recommend it to anyone! I went from 114 pounds to 140 pounds from being constantly hungry. I am an active person taking care of my horses and running every other day. And even that hasn't saved me. F 18 7 months
11/29/2008
 1  Menorraghia This stuff causes Adrenal Fatigue. You can actually verify how badly you have been adversely effected by this poison. Learn the lesson and avoid all forms of progesterone, including the birth control pill. This poison temporarily hurts your thyroid. Your thyroid is your fat burner. Avoid goitrogens (look this up if you have to). You can expect to go back to normal anywhere from 9-18 months. F 39 1 times
11/27/2008
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 1  easy to remember it caused me to be anxious, bloated, abdominal pain, cramping, I was always irritable and I gained a ton of weight which I couldn't lose afterword. I hated the way I felt when I was on it and it decreased my sex drive drasticly!!! It stinks... You always feel tired and nauseous. F 21 9 months
11/27/2008
 5  birth control no wait gain..NO PERIOD...no remembering the pill or patch for 3 MONTHS... i took it for a year and just this month switched to the ortho patch and i miss the shot sooo bad... the only bad side effect i had with it was acne, and the torture of getting a shot. i never once had a period the entire year i was on it, i did have very very llittle spot bleeding that was more dark and brownis but that would happen rarely and last maybe a day. i would recomend it to everyone!!! F 18 1 years
11/25/2008
 5  no periods or pregnancy no more cramps, heavy periods, extreme anger, uncontrollable cravings and missing school because of it. I actually lost weight on it, from 130 to 113 because I no longer had cravings and got a job where weight bearing exercises are what i do. As for mood issues I became much easier to live with. Defiantly do your research. It is true that some doctors might rush you out so get all the facts before getting The Shot. The only thing I experienced was a little dryness but it was better than awkward is-it-period wetness. Just remember to take extra calcium if your are younger and exercise. F 19 3 years
11/25/2008
 1  Heavy Periods due to Fibroid Tumors 1 injection on 09/24/08. I have been spotting/bleeding since 10/04/08. I will not be getting another shot. The bleeding is now heavy and does not stop. No sex because of the bleeding. My Gynecologist did not discuss the side effects of the shot. She acts like she just can not believe anyone has had a bad experience with this except for me. RESEARCH, RESEARCH before getting this injection. Please advise with any help to stop the bleeding!!!!! F 45 1 times
11/23/2008
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 1  Birth control Weight gain, migraines, extreme mood swings, and uncontrollable hunger. I have been on this medication for 5 years now, and I have been experiencing menopausal effects. I have hot flashes every night, I have gained 80 lbs since I have been on the medication, I have lost interest in sex, I have to use a lot of lube during intercourse which irrates my boyfriend because he don't like the residue feeling during and afterwards, I have become a very hateful person. The slightest thing will make me explode into a fit of rage at the drop of a hat. I have had to have multiple surgeries that are unusual for a person my age. I have severe headaches everyday that no medicine will subside. Depression comes and goes and is so random and at the worst of times. I feel as though that anyone who considers this drug may really need to do some research and ask their doctor to be 100% truthful about it and its side effects. I was unaware of the bone density loss that may result and was told at one of the most awkward of times and was instructed to wear estrogen patches for 6 m F 20 5 years
11/22/2008
 1  birth control weight gain (30 lbs), constant hunger, depression and anxiety, paranoia, mood swings and irritability, complete loss of sex drive, vaginal dryness and painful intercourse, dizziness, cramping and gastrointestinal discomfort, stomach bloating DO NOT TAKE THIS DRUG! It is poison to your body. From March-November 2008, I gained 30 pounds. I have not changed anything in my lifestyle other then that I am hungry ALL THE TIME while I am on Depo. If I don't eat I get light headed and terrible headaches. I also had a complete loss of sex drive and mood swings and anxiety that threatened my marriage. These were completely new and I had never had this problem before. Every time I tried to talk to my doctor or the nurses, they acted like I was crazy and said my symptoms couldn't possibly be the Depo. Now I find out that my doctor didn't bother to counsel me on the fact that I should have been taking extra calcium this whole time and I have to get a bone density scan to be sure I don't have osteoporosis and I'm 31 years old! If you do research on this drug you will see that it never should have been approved by the FDA. I trusted my doctor and thought she wouldn't give me something that wasn't safe. I was wrong. Don't let yourself be t F 31 6 years
11/19/2008
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 3  Migraines 1st 2 years: fewer migraines, no period, weight loss, increased sex drive around shot time and shortly after decreased in between shots, vaginal dryness, massive mod swings, possibly some paranoia, for the most part the good outweighed the bad After 2years and counting - migraines are the same as they were before, massive weight gain, can't lose it, diabetes (possibly because of depo or as a result of weight gain), tired all the itme, no period, MASSIVE vaginal dryness - needed a cream, yes ladies it can shrivel up from non use....developed HPV - didn't turn to cervical cancer, constant hunger, dizziness, weaknees, no energy, lack of concentration, joint pain, developing allergic reactions... gonna be honest, there's more the list is huge. I loved Depo the first two years but as I hit that two year mark I started to get wingy. It's been 6 now...The side effects that suck no longer outweigh the good ones. I am going to get off of it. Just gotta find another way to keep the period away - mom likes her IUD. F 26 6.5 years
11/17/2008
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 3  Severe menstrual cramps! Irritability, mood swings, anxiety attacks, depression, lost weight, have zero tolerance. After 1st shot, experienced brownish discharge everyday had to wear a liner all the time, no periods, occasional light cramping. I'm at my wits end with my mood swings and being mesirable all the time. Taking anything and everything out on my family with constant yelling...husband cannot tolerate it any longer and is putting a strain on our marriage! My reason for taking this was to have light periods and no cramps! Now I have no periods, and slight cramping & a bunch of ATTITUDE! I've taken my second shot last week..which will be my last! Another doctor told me that they are pulling this off the shelves due do bone density, my age I'm at high risk. Oh yeah and lack of sex = NO SEX! F 39
11/14/2008
 4  birth control Took Depo for 10 years...no period at all for a whole decade!!Side effects...decreased sex drive, decreased breast size F 29 10 years
11/10/2008
 3  birth control weight gain...5 years 20lbs didn't have periods before now that I'm going off I wonder if I will now. F 41 6 years
11/10/2008
 2  birth control CONSTANT BLEEDING, vaginal dryness, ZERO sex drive, vaginal stinging, rectal bleeding, depression, irritability i originally began taking the shot about 3 months ago. i was supposed to get my second dose about a week ago, but have decided to no longer subject myself to these hormones. at first i thought i might have been depressed because of my recent move to a college hours away from home, but now that i'm reading all of these similar experiences, i'm beginning to think it might be the shot, as it al began a few weeks after my injection. the constant bleeding has been the worst - i'm sick of constantly bleeding through tampons (the heaviness of bleeding is unpredictable). and then who wants to have sex with blood-stained underwear? my boyfriend is constantly worried he is hurting me when after sex there is blood evident. the dryness has also been a great obstacle, as my boyfriend is often convinced i'm just not turned on, (and honestly, a lot of times i'm not - hence the zero sex drive). the vaginal stinging is relatively new as i've only been experiencing it for the last couple of weeks, but i F 18 3 months
11/10/2008
 1  Birth Control Method Anxiety, depression, fatigue, mood-swings, weight gain even though I regularly work out for a minimum of one hour almost every week-day (burning anywhere from 500-1000 calories per work-out), brown discharge alternating with brownish red period non-stop for 9 weeks, vaginal dryness, dis-interest in sex, racing heart right after shot and occasionally, sex is painful and I always have a muddy discharge during and after sex that grosses out my husband. After experiencing all of these side effects and doing more research on the product I have concluded that it is not a healthy option. Shame on me for not really researching prior to getting treated, but even the warnings on the packaging right from the pharmacy state that this "should only be used as a last resort method for birth control when no other method works, and it is not recommended for extended use beyond two years." Seems dangerous to me. I will not be getting another shot, and I do not recommend this method. F 28 2 times
11/10/2008

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