DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  birth control depression,anxiety,nausea,irratablity im not getting this shot ever again i still have two months until im due for another shot. i feel like i am a crazy person, i act pissy all the time and the smallist things piss me off. i am getting married in a few months and im scared that the way this shot is making me act he might run.dont take this shot!!! F 21 7 months
1X day
7/25/2010
 1  Prevent Pregnancy Mood swings, anxiety, heart palpitations, depression, low sex drive. I use to think Depo was the most amazing thing! Now I am realizing that it is the reason for all of the listed symptoms. I couldn't figure out why I always had these symptoms every time my shot was due or right after I received it. It is like bring a crazy person every three months. My relationship was almost ruined by it. F 24 3 years
100mg/ml 1X O
7/22/2010
 3  birth control Depo was great at first, especially since it seemed to be the only thing that prevented unwanted pregnancy for me. However, I noticed the "doom" started setting in. I became extremely depressed, moody, gained weight, and started to get a lot of acne.I really didn't think much of it because it was so effective in other areas: I didn't have to worry about getting pregnant if I got my shot every 3 months. I've been off the shot for 2 months now (not in a sexual relationship anymore) and I'm feeling a lot more side effects than I had while on the shot: stomach pains, panic, extreme moodiness, fatigue, low self-esteem, overall negative self-image, a bit more weight gain, dizziness and nausea. I get these heart palpitations out of nowhere, which really freaks me out because I have never experienced anything of the sort. Until reading all of the comments, I didn't realize that my problems may very well stem from Depo. As this makes me feel a little more sane, I'm really hoping the s F 25 2 years
1X day
7/21/2010
 3  eliminate monthly menstrual cycle excessive weight gain, joint pain, no cycle first 5 months, no sex drive, always hungry i absoluted loved my depo provera shot up until july 1 2010. I started spottin which i eventually expected, but now 22 days later im still bleeding! I got my 3rd shot this year yesterday and i definitely know it will be my last. Never again. F 20 6 months
injection 4X O
7/21/2010
 3  Convenience I loved the shot as I didn't have to take the pill every day. I experienced some weight gain (about 10 pounds), but no pain or major mood altering while on the Depo. My issue occured after I've been off the pill for about a month and immediately went back to the pill (I plan on starting family in a year or so). Since I've been off the shot, I've had major acne breakouts, headaches, nausea and some depression. I haven't had a period yet, but that's because I immediately started the Pill. I'm reading the comments about the never-ending period and hope I come out okay, but at least I'll know what's going on if it happens to me. On the plus side, my weight is coming off slightly easier then it did while on the shot. Can't recommend to anyone, but was not a wholly negative experience for me. The withdrawl symptoms are worse for me than the drug side effects. F 28 1 years
UNK 1X O
7/20/2010
 1  Birth Control hair loss, extreme weight gain, depession, mood swings,sporatic periods that would last 1-3 months, severe acne,anxiety, loss of sex dive, pregnancy resulting in miscarriage. I DO NOT recommend this to my worst enemy! my hair was falling out in clumps, I was extremely depressed, and I had not an ounce of a sexual drive the entire time I was on the shot. The last straw was when I got pregnant on it and then had a miscarriage. Once that happened, i decided that it just wasn't worth it anymore if it wasn't even preventing pregnancy for me! F 22 12 months
1X O
7/17/2010
 1  To not be pregnant Makes you bleed continously, like every other day. It is very unhealthy. Low sex drive, Moody. I hate this depo-provera shot. I dont recommend it. F 21 3 months
150 mg 1X O
7/16/2010
 1  Birth Control Extremely heavy and constant bleeding including passing of large clots, depression, aggression, joint pain, total loss of libido, loss of energy, hypertension. Taking Depo-Provera was worst decision of my life. I advise anyone considering it to really really look at the side effects and seriously think if it's worth it, but I promise you, it ain't! F 23 3 months
1X AN
7/15/2010
 1  to stop bleeding from fibroids All of you that are having these horrific side effects from this drug please contact the FDA with your complaints. I called them and they didn't have any. Please, Please, contact them and let's get this drug off the market before it hurts any on else. F 53
1 shot 1X day
7/15/2010
Patient History
 3  Birth Control I've been on Depo for about 2 years and it took about 6 mnths 4 me 2 get used 2 it. I had irregular bleeding for the 1st 6 mnths aftr that only once every 3 mnths which I LOVE! I noticed aftr the 6 mnth mark that I'm a lot dryer down there and that I was getting mad painful acne all around my mouth, chin and neck area which is hormonal. I've been trying to deal with it for the past year and a half trying different skin care and such but no luck and I am done with it. I hate lookn @ myself in the mirror and wnt go anywhere without makeup on. Also I have joint pain which I didn't know was a side effect until I read other peoples comments. I love not having my period and not having to worry about taking a pill every day but after 18 mnths of having to buy extremely expensive skin care and dealing with painful cystic acne I'm done. Going to make an appt to talk 2 my Dr about it. Not sure what to do because the pill wasn't wrkn 4 me as I would have my period for 3 mnth s @ a time! Why is it F 24 2 years
1X AN
7/11/2010
Email
 3  Eliminate terrible period symptoms. Severe joint pain, no sex drive, painful intercourse, irritability, lightheaded, fatigue, and excessive tiredness, but no periods or spotting whatsoever. I took this drug a few years ago for a 2 year duration and am recalling similar side effects that I'm experiencing now and hadn't realized then were related to this shot. I realize that everyone will react differently to any drug, however, many of the side effects I'm experiencing other women seem to be experiencing at too high of a rate for my comfort. This shot would be great if I wasn't in a committed relationship and never planned to have sex, my relationship is suffering because I can't stand to be touched anymore by my boyfriend whom I've been dating for 8 years. The shot works perfectly to eliminate periods in my system. However, I've been waking up every hour of every night because of the joint pain which doesn't even seem to be treatable with the Percocet I've been taking on a regular basis. Before this birth control method, I was taking Seasonique which was working perfectly with no side effects for me. The only reason I switched was due to my doctor's recommendation because of occasional migraines that were caused by another medication I was taking at the time. F 22 3 months
1X O
7/7/2010
 1  Birth Control Immediately starving after getting the shot, constantly starving after getting the shot, joint pain in shoulder and knees, night sweats, vivid dreams, increased sense of smell, morning sickness, weight gain (almost 4 pounds in one month), bloating, depression, mood swings, fatigue and exhaustion, skin rash on face, hair falling out everyday, bleeding after sex, bleeding heavy for 10 days, passing HUGE clots, dizziness, sore breasts, decreased sex drive, ovary pains, alcohol aversion, smoke aversion, all over body aches. It's like being pregnant, except you are not pregnant, constantly starving, taking SLIM SHOTS to reduce appetite. Cannot have sex because of heavy blood flow, feeling the worst that I have ever felt. Passed clots so large I was worried for 3 days. At least pregnancy has a purpose. I don't think that I can continue this treatment. F 32 30 days
1 shot 1X AN
7/7/2010
 1  contraception Nausea, dizziness, pressure on temples, back ache, blurred vision, i was flinching at stupid things paranoia I have come off the injection now. I was told that the only side effects wer abnormal bleeding. My nurse laughed at me when i mentioned all my other side effects i now know i'm not crazy. F 20 3 months
1X M
7/7/2010
 1  to prevent pregnancy Weight Gain, Extreme Cramps in my abdominal and chest area, Head Aches, The worst stretch marks ever in the area around my uterus Concerning my stretch marks that I have on my stomach. I know that they did not form naturally because they started to show in the form of a ring around my belly button! The stretch marks have gotten much worse, to the point where I cannot wear a bikini to the beach which is very disappointing. Naturally I get depressed about my self image since I have weighed more than I currently weigh yet when I look at my stomach I feel like I look horrible. I have tried using cocoa butter and Mederma to treat my stretch marks but I desperately hope that once I change my birth control the stretch marks will calm down and the theraputic lotions that I use will have a greater effect. I do not suggest this type of birth control and I personally feel stupid for taking it. I have been on depo for about a year and I'm 19. I wish I wasn't as against pills but the shot is given too much credit in regards to my personal opinion that I formed from my experience. Perhaps the shot works better with others but I think that other than preventing pregnancy this shot created more problems than solutions. Therefore I don't advise others getting depo, even though the convenience makes the shot sound very appealing. F 19 1 years
1X AN
7/7/2010
 1  Birth Control Weight gain, fatigue, depression. I am the kind of person who loses weight fast. I don't even have to do cardio....just sit ups and I'll lose weight. But now I am working out like crazy! I think to myself why am I not losing anything? and I finally figured it out...DEPO! I was 160 before I had my son and now I am just staying 190-200. I get depressed at random times...at least 3 times a week. I cry out of no where. I am also extremely tired through out the day. I feel drained and so lazy. I hate what Depo has done to me. My last shot was in June 2010 and I am just waiting for it to get out of my system. I am going to try everything and detox my body. I just pray to God that I don't get those nasty effects like never ending bleeding or more weight gain. TO ALL WOMEN...DON'T TAKE DEPO PROVERA! IT WILL RUIN YOUR LIFE!!!!! F 20 1.5 years
6X O
7/6/2010
Email
 1  To control heavy bleeding moody, stay emotional, severe abdominal pain, nausea, headaches, loss of appetite, no sex drive, fatigue all the time, loss of hair. This is my first time taking the shot. I took the shot back in May to control my heavy bleeding. I would not recommend this shot to anyone. I started spotting June 8th. And every since I have been bleeding. The abdominal pain is unbearable. I ended up in the emergency room. I am still bleeding right to this day. They told me that this was to control my bleeding but I have bled more this way than having a normal period. At least I know what to expect when My period did start. I rather bleed for seven days and have a couple of days of heavy bleeding than the unknown of not knowing when you going to stop. this shot sucks. Im bleeding heavy and dropping clots and losing alot of blood to the point I feel as if im about to pass out. To anybody thats thinking about taking this shot, educate yourself and ask your doctor about the side effects cause my doctor didnt tell me anything and give me any type of information. F 37
1X day
7/5/2010
 1  Responsible Married Woman During: nausea, headaches, excessively tired, bled for 2 of the first 3 months, acne and eczema increased, reduced libido After: no spotting or period at all since the end of the shot (it has been a little over 2 months), acne and eczema extremely unbearable, joint pains especially in jaw joint, greatly reduced libido, full body aches, random skin rashes, bloodshot eyes that will not go away I am a 27 year old at 5'7" 130 lbs. and healthy with the exception of this dreadful Depo in my system. This is the worst thing on the market for people trying to be responsible about having children when they still want to have children someday. I only see one reason to take Depo and that is to treat PCOS or for sterilization. My husband and I want to have children someday. I took the Depo because I wanted to be period free during our one year wedding anniversary in Mexico. Now, I have had no menstrual cycle and am concerned that I may need hormone therapy if we ever want to have a child. HOW TERRIBLE THAT THIS IS APPROVED SAFE!! SAFE!??? Really? From all these experiences, I would never imagine to call this SAFE. TAKE THIS OFF THE MARKET AND DOCTORS, PLEASE FULLY EDUCATE YOUR PATIENTS AND TALK THEM OUT OF THIS POISON. F 27 3 months
1X O
7/2/2010
 2  Birth control I was told that I probably ouldn't have a period with this, YAY! HOWEVER, I have been spotting since I started the shots in Jan. ALSO, I now have Menoraghia (heavy uterine bleeding) with HUGE clots. I have bled for 20 straight days. I am going to a different Dr. this Fri. If not for the constant bleeding this would be a fabulous birth control for me. F 50 6 months
150 1X O
7/1/2010
Email
 1  BC loss of about 1/3 of my hair lost 10 lbs in fist month (went from full B bra size to A) to much to list...... 1 shot feb. 2nd 09 (1year 4mts ago) OMG PLEASE HELP!! when will this END!!!! lost 10lbs first month of taking it and lost a full cup size! I have gained the 10lbs back but my breast did not come back w? that!! periods are still all messed up, my hair still falls out, I run 3x a week to stay active and tone up but my body just wont tone up... my breast are still @ a A cup but Im always still so Fatigue..... when I wake up Im sleepy, I need a nap @ about 1 pm and 6pm..... I noticed all this about a month after I got this shot! If you have any advice please let me no..... I've tryed talking to my DR but she blows me off and says it will get better BUT WHEN???? I don't no what to do any more I don't like living like this! I have a 6 year old little boy who wants me to play w/ him and I just can't Im always so sad and angry (oh yeah mood swings to) And my little boy says mommy why are you always so mean) yep thats how I know its the depo!! HELP PLEASE! F 26 3 months
1X O
6/28/2010
Email
 1  contraception mood swings, weight loss due to depression which led to early stages of anorexia, dizziness, nausea constantly tired, severe abdominal pains, bleeding DO NOT USE THE DEPO!!! (one injection once every 12 weeks) i went on the depo when i was 19 as it was far easier for me than taking a pill everyday, my local nurse recommended it saying it is one of the best forms of contraception. However now im 22 and have been off the depo for a year for a few reasons...6months into using the depo i started getting cramps and thought nothing of it then shortly after i started to feel slighty tired and light headed and quite emotional, after 12-18 months i started feeling extremely depressed and from there my side effects started, the final straw for me was after nearly 2 years i started to have light bleeding spells then when that stopped i have server abdominal pains to the point where i couldn't move. After serious discussion with my partner he agreed i should come off it clear my ststem of the drug and start planning a family. 6 months after i came off the depo my periods returned, irregular and after a year of no contraception we still have no baby and no sign of pregnancy so i started to do a bit of research... Doctors and nurses don't tell you how dangerous this drug is, it can make you infertile and can take anything from 6months to 2years for fertility to come back to normal, periods can take up to a year to return, your mental health can become effected -depression, emotion over drive hormones flying all over the place. I'll never ever go back on the depo and hope I've helped you make your decision. F 22 30 months
1X AN
6/28/2010

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