DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control Continous bleeding, massive mood swings, angry, depressed, cold, scared, and jealous I had this shot administered by planned parenthood, the dr told me because I was too old and I smoked that this was the only thing she would give me. I had my period when I got the shot, it ended for a week and then came back and has not left. This has been over a month now. Hubby says he understands how this is birth control cause I have my period constantly! He is upset with the fact that I had to pay to have my period, constant arguments with him, depression, mood swings, I am always freezing, I have fears that I have never had before and I am extremely jealous over nothing! He is really upset that I paid for all of that. I will say that I will never take this shot again! Hopefully with this first shot it will not affect me as long as it has some of you. I feel so bad for all of you! I hope you are all fine after this horrid thing wears off! Hopefully, after of all of this, I can convince hubby to get a quick snipping done and soon! You are all in my prayers! God Bless F 36 1 months
2/28/2009
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 1  birthcontrol method MIGRAINES! weight gain and constant spotting/bleeding I got the depo shot 2 days after I gave birth to my second son. I wanted the convienience of not having to take the pill. I will NEVER get the shot again! I've gained weight, I get migraines and I have been on my period since I hgave birth to my son almost 3 months ago! NOT FUN! To top it all off I have ZERO SEX DRIVE! My sister was on the shot for 5 years and she now has major thyroid problems and it ate away at her bones! This stuff is bad news and because of what it did to me I faithfully take my pill everyday! F 23 90 days
2/26/2009
 4  Had terrible periods About 2 to 3 lbs weight gain it would go down then up, slightly depressed ever so often other than that it is pretty great Depo helped out a lot as far as stopping my periods, the cramping was terribly painful and it would stay like that the entire length of my period. Weight gain never became a problem, my doctor warned me not to be on it for over 4 years I think due to some bone loss if you didn't take vitamins or calcium supplements. I did have a bone scan and I was losing density in my hips, so that is the reason I got off of it. Very conveinete in a sense of not having to remember a pill everyday and only having to go to the doctor every 3 months. Overall it is really good alternative for a few years but I was on it for 7 years and now I am trying the Ortho Tri Cyclen. F 23 7 years
2/24/2009
 1  Birth control Spotting sometimes several times each month. Anxiety, paranoia, depression, and anger that seemed to come each month during PMS time. Would usually last about 2 weeks. No sex drive. Depo may work well for some people, my best friend loves it. It made me feel like I was going crazy. I have decided to quit taking it. F 31 1.5 years
2/24/2009
 1  birth control At the time, I suffered blood spotting and weight gain. I was on it continuously for 3 years. It was only after I got off it that - in hindsight- I had many more symptoms. These include mood swings, irregular periods and dryness, among others relating to early menopause. I have only now just been diagnosed with early menopause. The symptoms - in hindsight - started with the use of depo-provera, although I hadn't realised at the time. Over the last 7 years, the symptoms became progressively worse, until now where I need to take HRT due to lack of oestrogen. I doubt I would have had these symptoms if I hadn't taken depo-provera. Oh & forgetfulness is a symptom of early menopause as well. I had a fantastic memory and now due to short term memory loss, I don't. So all symptoms of early menopause can be found elsewhere - and that is what depo-provera has given me. F 36 3 years
2/23/2009
 4  Birth Control During the first year I experienced some spotting, usually when it was time for the next shot. Some vaginal dryness, but that is about it. I have had no severe issues with the shot. After reading all the comments I have become concerned. Also, my husband and I are thinking of having another baby and I am afraid it will take a while to become fertile and conceive again. F 23 2 years
2/20/2009
 1  I have severe endometriosis For the first 2 months or so I felt completely fine. The only problem I had was spotting and my doctor said that was normal and would go away after 3 months. Around the 3rd month I started to feel completely different! I started to feel depressed, cry over EVERYTHING, headaches, LOSS OF SEX DRIVE, extreme pain during sex ontop of the pain I already feel from having endometriosis, vaginal dryness, BAD mood swings, starting to slowly gain weight, and feeling hungry more often. I've been on this shot for 4 months now and I feel like a completely different person! My boyfriend has even noticed I've been different! AND my spotting didn't stop after the 3 months! It's been 4 almost 5 months and I am still spotting...its really gross! I am going off this shot! It's horrible!!!!!!!!!! I get annoyed so easily or I'm super emotional and I cry over anything...I feel like an emotional rollercoaster...happy for a min angry the next then I'm crying! I CAN'T WAIT TO GET OFF THIS SHOT AND FEEL NORMAL AGAIN!! I hope anyone who is thinking about going on this shot reviews it first! :( F 19 4 months
2/20/2009
 1  birth control Weight gain, depression, mood swings, paranonia, insomnia, fatigue, lower back pain, increased hunger, memory loss, no energy, possible endometriosis, crying fits,delusions I think it really depends on the person but I took the shot in December and have nothing but negative side effects. The doctor warned me of the "normal" ones but if she told me how it really was going to be, I would have said no. Haven't been able to lose any weight even though I am working out at the gym almost everyday doing tons of cardio and strength endurance training. I am also hungry all the time too. I start fights with my boyfriend every other day to the point now that when I tell him I love him, he responds "love me today, hate me tomorrow." I haven't wanted to see my friends, pretty much avoiding them, even their phone calls. Crying spells all the time. Sometimes putting the cereal in the refrigarator and the shrimp in the cabinet and a few minutes later realizing what I did and trying to figure out when I did that; things I was already paranoid about being more intense like thinking that there are cameras in my room or someone looking at me from the ceil F 22 3 months
2/19/2009
 1  help ease menopause Loved it for first 3 shots...then had several UTI's, pain when urinating, severe depression, terrible head aches, swelling in hands and feet, ache everywhere (especially in back and ankle where I'd had injury in the past) I've been to several specialists, had a CT scan, a scope of my bladder, sonogram, they found NOTHING...then I go to St Luke's hospital and find out it's the damn depo. I am miserable...I miss lots of work, scheduled for hystorectomy next month and hope like hell I get back to normal when this poison gets out of my systom. F 46 18 months
2/18/2009
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 2  prevent pregnancy minor abdominal craps, tiredness, extreme pounding headache, shortness of breath, heart palpitations, nauseau I saw my doctor about some dizziness/vertigo I was experiencing. Before she gave me a prescriptions, she did a pregnancy test to make sure it was safe for me to take the medication. I went for a followup and she asked if I was on any kind of birth control. I told her no because I've had problems with other kinds of birth control before. She quickly goes on to tell me how great depo prevara is and that I should be on it, side effects are minimal, its the best out there for me. It was so sudden, I didn't really have time to think to really ask any important questions. Any questions I did ask, my concerns were downplayed and all I heard was how great this would be for me. So I went ahead with the shot. Now I'm having these side effects, the headache is extremely intense. I've only been on it for about a month. Has anyone else been in my shoes, will the side effects eventually calm down? If this continues, I want OFF! HELP! F 30 28 days
2/17/2009
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 1  PREVENT PREGNANCY NO PERIODS AT ALL, MOODINESS, CRYING ALL THE TIME, ANGER, DEPRESSION, SUICIDAL THOUGHTS, FATIGUE, UTI'S, JEALOUSY, WEIGHT GAIN ONLY IN MY STOMACH I have been on the depo shot b4 when i was single, & i loved it b/c prior to taking the shot i was under weight and i gained a healthy amt of weight. Months later I started dating now in a serious relationshp, I absolutely hate the way i feel. I am always crying, always depressed, very tired and never in a good mood, i get very annoyed by everyone, especially coworkers and its effecting my job, i over anylize EVERYTHING, sometimes i feel like life isnt worth living, i havnt talked to any of my family, i have a toddler boy and i feel like im not as close to him as i was b4 :( , i dont think i will be taking this shot anymore .. i would much rather have a baby than to feel like this. F 23 5 months
2/16/2009
 1  i had terminated a pregnancy, i experienced bloating, weight gain, depression, mood swings, hair loss, headaches, dry skin, a very foul odor from my vagina, and alot of discharge. i took the shot to avoid another pregnancy because i had just terminated one. i only took one shot that was in june. i got my period back in december about the 26 to be exact. during those months without my period i experienced all the symptoms mentioned on the left of the screen, now that my period has returned i have been experiencing pain, i mean pain during intercourse. i have to hold my stomach if i try to make a bowel movement or urinate. the doctor can not tell me what is wrong because he cannot find anything. but i know that it is from that damn shot. F 24 3 months
2/16/2009
 1  Extreme PMS WEIGHT GAIN & CELLULITE!!!!!!!!! I gained 30 lbs in six months & got cellulite in places I never imagined a person could get it!! I still can't get rid of the cellulite or all of the weight!! It's been several years and lots and lots of exercise, super spinning bike classes for just one thing. I always had the matabolism of a humming bird until I took this shot and when I talked to my doctor he said the shot would not cause weight gain. I guess he thought I had suddenly become a gluttonous pig that ate non-stop, but no, he knew it was the Depo, I wasn't sitting there stuffing my face while in his office. He must have been getting a kick back from the drug company to tell someone with that kind of sudden weight gain to keep taking what was causing it. Doctors take an oath to do no harm but that was obviously a joke to him. We all know too much weight is unhealthy. I'm not stupid!! I changed doctors!! This shot completely ruined my body forever!!!! If you would love to gain lots of weight and have lumpy, bumpy cot F 35 6 months
2/16/2009
 1  birth control Severe depression, INTENSE ANGER, sudden weight gain, hair loss, decrease in sex-drive, dissatisfaction I would never recommend the shot to anyone, it's terrible. I can't wait until it leaves my system. F 20 6 months
2/16/2009
 1  birth control during breastfeeding anger, rage, restlessness, sex drive increase, annoyance, irritability, dissatisfaction I was ANGRY all of the time, at my husband, random strangers, even my poor 3 month old baby girl! I wanted to hit a wall instead of hitting one of them. I was restless, found it hard to sleep and my sex drive actually increased but I was unable to do anything about it as nothing seemed to satisfy it. I think the only solace I could get was going for a run until I was exhausted then a long bath. Minor annoyances would set me off, and I found it very hard to reason or focus. It did work as birth control - but I would never put this in my body again. F 29 3 months
2/13/2009
 1  painful periods/birth control Panic/anxiety attacks, depression, hair loss, weight gain, hypoglycemia POISON!!! I started getting the shot in March of 2007. In September, the day after I had my 3rd shot, I was rushed to the ER with severe anxiety attack and hypoglicemia. Four days later another anxiety attack and another trip to the ER. I asked my OBGYN if these symptoms could be related to the shot and she always told me absolutely not. So I kept getting the shot while my nightmare of panic, anxiety, palpitations, depression and hypoglycemia was getting worse and worse. I was afraid of sitting home alone but also afraid of going anywhere by myself. Even walking into the grocery store would give me palpitations. I’ve always had a very busy life and could not understand why all of a sudden I was not able to do anything anymore. Then about a month ago I decided to do some researches online. I could not take it anymore. OMG!!! I could not believe how many women had the same symptoms!!! I don’t know why I did not think about it before but I was glad I had found out just in time F 45 20 months
2/11/2009
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 4  prevent pregnancy spotting off and on, anger It's been a month and so far it's been ok, i just started spotting last week. I haven't had a period since my baby was born (5 months ago) so this might just be my first one. Problem is it's been over a week. As for the anger issues, it could just be being frustrated sometimes. But i don't recall ever being that angry. Other than that it's been great so far. I'm not pregnant so it's doing it's job. Also i've still been able to continue breastfeeding. No weight gain, sex drive is fine. No dryness that i've noticed. Then again it's only been a month. But all these comments on here kind of scare me so i don't know if there'll even be a second shot in my future F 29 6 weeks
2/9/2009
 1  Prevent Pregnancy WEIGHT GAIN....ANGER>>>lots of it depression, fatigue, aches, GI problems, etc. I stopped taking the Depo shot a little of 2 years ago and I am still having all the side effects you can think of. I've been so angry to the point that I lost all of my friends. I've been depressed and had many many GI problems....I just received my period back about 8 months ago but it is not normal at all. I'm married and I want to have children now but my body won't start ovulating (due to depo) and I have had many ovarian cyst (also due to depo). I've known my husband since before I started depo and he tells me that it's so obvious I have changed but due to all these HELPFUL comments regarding the shot, he understands completely. Don't get me started on the weight gain. Before I started depo I was 235 pounds. I've always been big boned so when I gained a little bit I thought it was normal...the little bit did not stop. I have gained a total of 70 pounds due to depo and I can not lose it no matter how hard I try!!!! THIS SHOT IS EVIL AND I FEEL LIKE IT HAS STOLEN SO MUCH OF F 21 2 years
2/9/2009
 1  Birth Control Migraines, Hair loss, Much more emotional than I have ever been, Pain during intercourse, Recurring urinary tract infections and yeast infections/vaginitis This is really a terrible drug. It worked great for about 2 weeks before I started having problems. It really bothers me that it's so painful to have intercourse, I feel so bad for my poor boyfriend having to deal with it just as much as me. The thing that scares me the most though are these recurring UTI's, I'm scared it might really be a serious problem. Please don't get this shot. F 17 1 times
2/9/2009
 1  TAKEN ORAL PILL FOR 20 YEARS After first week bloating, acne and then cysts started forming under both arm pits. Over over the next 3 months continuous heavy bleeding. Extreme weight gain which looked like puffiness. The cysts became unbearable needing antibiotics. My first Depro injection 1995. I've always had a normal 28 day cycle. The injection was advised as a suitable replacement to the pill which I had taken for 20 years. The doctor was keen to use it saying side effects were rare. The adverse effects kicked in within a week. Bloatedness leading to weight gain. several cysts reoccurring under each armpit making any movement unbearably painfull. The periods did not cease and STILL HAVEN'T. I couldn't wait for the drug to leave my system but foolishly convinced by the GP the symptoms would pass if I kept with Depro so I allowed another toxic dose. The cysts got worse, the weight increased along with heavy dull aching periods constantly, plus deep aching lower back pain. I had 3 children plus a part time job to maintain at that time. Moving on I'm still bleeding continuously and suffer anaemia leading to extreme lethargy intermittantly. This constant bleeding definately affects my health. Osteosporosis was diagnosed at 41 with an early meno F 45 6 months
2/8/2009
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