DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  PREVENT PREGNANCY MOOD SWING, GALLBLADDER REMOVED, DO NOT TAKE THIS DRUG!!!! F 18 1 years
12/13/2009
 1  Birth Control No period, head aches, body aches, joint pain, anxiety, weak, back aches, sensitive skin, weight gain, hair loss, depression, mood swings, low sex drive I was put on the shot shortly after having my 1st child, whom i got pregnant with while i was on the pill(at 17 yrs old). I was on the shot for 3 years with no problems, my doctor told me it wasnt reccomended to recieve the shot more than two consecutive years and that i should consider switching to a new method. So it was back on the pill, shortly after, while on the pill, i became pregnant with my 2nd child. After she was born i insisted i be put back on the shot since it seemed to be the only method that works and it was just a bonus that i had no period. That was 2 years ago, and I am still on the shot now but have recently noticed over the past year my body has felt like its falling apart. I feel very weak, and achy, my skin is very sensitive, ive had major hair loss, my weight is at a halt and no matter what i do eat healthy, eat junk, are active or do nothing, its at a stand still. I've had horrible pains in my ankles, knees, and wrists. It hurts to walk down the stairs, sometimes i cant even hold my 30lb child because i am so weak. I always blamed this on bad diet, not enough vitamins and what not, but the more i read into depo, the more im starting to believe that im not falling apart, the depo is destroying me! After 5 year of what i thought was a miracle drug, last week was my last shot. Im going to give my body some time to recooperate and see what happens from there... F 25 5 years
12/12/2009
 1  Contraception Weight gain (4st in total), complete lack of sex drive, Thrush, Depression, Panic attacks and many more! I was on Depo due to not being able to have the pill. I came off it in July 09 and started my first period two weeks ago after not having one for five years. I has not stopped since. I currenlty have really bad cramps, feel dizzy and sick, totally exhausted and very tender breast.My symptoms seem to be getting worse and NHS Direct say that this is normal after coming off Depo!The worst side affect for me was the painful sex and thrush which nearly wrecked my long term relationship. I would advise anyone who is thinking of going on Depo to seriously consider other options. If I could turn back the clock I would not have gone on it!It maybe the easy and lazy option but in the long term you pay for it! F 22 5 years
12/10/2009
 1   I just gave birth in September, & on my postpartum check-up, I wanted to go on any form of bc that is really good. So my Dr. prescribed the depo.. After 2 weeks, I started to notice back aches & anxiety attacks, I didn' t know that it was anxiety, So the first time that I had it, I panicked because I had shortness of breath, & went into the ER. I did all kinds of tests; scan,heart ultrasound, x-ray, Ekg.. & to my surprise, they all came out normal. The doctor told me, I don't know whats the problem here, but everything seems to be normal. It must be anxiety that you're having. I was so shocked, because I never thought I would go through such a thing! So I did a follow up at my regular doctor the next day and she told me that it was the depo shot that caused my anxiety, so I'm not going to take that anymore. Up until now, I still have shortness of breath & I get startled easily. I've gone to a therapist, but it doesn't seem to be working, I Do not take this shot! F 19 1 months
12/9/2009
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 3  Painful periods Acne, 60 lb. weight gain, moody, depressed, absolutely no sex drive, loss of period (happy about that one) I got my first shot in April 2008 because my period got so bad I was willing to try anything to stop it. No doctor will perform a hysterectomy because of my age so I tried the shot. It worked, I never had a regular period after that. I would have spotting but that's it. Now, 9 months after my last shot I still have not had a period. I stopped getting the shot because I gained 60 pounds. My poor husband has stood by me the whole time even though I know it's been miserable for him because of me not desiring sex at all. We were both miserable. My sex drive is still low but it's better than what it was. I developed another symptom early in 2009 but I'm not sure if it is because of the Depo or not. I began having these tics and was referred to a Neurologist who thought that it could perhaps be Adult-onset Tourette Syndrome but now he's thinking Dystonia. I'm supposed to see a Movement Disorder Specialist later this month to see if they can come up with something. Has anyone else had anything like this happen? F 27 1 years
12/8/2009
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 5  period control / birth control none i took depo for 15 years - from the age of 15 to 30 years old. for me it was the wonder drug - i had no side effects and no period for 15 years. i maintained a weight of 100 pounds the entire time and was so happy. a year ago, my obgyn sent me for a bone density scan, and it showed that i have the bones of a 90 year-old woman - very frail and brittle. she demanded that i get off the shot immediately in order to reverse the loss. i was on the nuvaring during the last year, which has sent my weight to a whopping 150 pounds, which at 5'4" is ludicrous, considering i have gained half my previous weight and now weigh 1.5 times what i used to. i no longer recognize myself, both physically and internally - just don't feel right, don't feel like myself. i had a mirena iud inserted last week in order to get my body back to the condition it was in during the depo, so i am currently hopeful. had my doctor not refused to continue giving me this shot, i would still be on it. F 31 15 years
12/7/2009
 2  Birth Control Extreme weight gain (40 pounds), sex drive remained in tact This drug causes weight gain and decreased bone density. Immediately after switching to the pill, I started to lose weight. F 22 1 years
12/7/2009
 1  birth control and regulate periods headaches, decreased appetite but weight gain anyways..muscle and joint aches, irregular bleeding, bad cramps, heavy bleeding worst form of bc EVER! idk where to begin..this is the first bc ive ever taken and my doctor told me that it would eliminate my period and i wouldnt have to take a pill every day. I got a bruise on my arm from the shot but thats the least of the side effects..before this shot i rarely got headaches and considered myself lucky but during the 9 months they were atleast a couple times a week id say. For the first 2 months i didnt have a period which was great, and then about 10 days before i was supposed to get my next shot my period started and didnt stop until i got the next shot. Before getting depo i never had cramps either, but on it i would get cramps where id be doubled over in pain and just couldnt even move until it was gone. The blood was more of my uteran lining then blood which worried me because it was never like that before. after the 3rd shot i decided not to get it anymore because instead of not getting a period like my doctor said, i would have it for 2 or 3 weeks at a time. so to answer the question if it works as a birth control, the answer is yes, because you never get the chance to have sex except one lucky week a month MAYBE. ive now been off of it since Nov 11 (now Dec 7) but have had irregular bleeding/spotting since about the first week of Oct. I can't go anywhere w/o pads. Now that i'm off it my stomach seems to feel and look a little flatter even though the scale reads the same..NO i would NOT recommend this product F 18 9 months
12/7/2009
 1  Contraception Acne, oily skin & hair, vaginal dryness, night sweats, numbness/tingling in hands & arms when sleeping, swollen breasts, weight gain around the waist I got oily skin & acne from the start, assumed it would settle down but it never did. After the 5th injection the other side effects suddenly got a lot worse so I decided to stop taking depo. A year & a half after my last injection my periods are only now getting back to normal (I had them about every 2 weeks for 9 or 10 months). I also have swollen breasts & discomfort in my upper arms & legs due to swollen glands for the past 5 months. Thankfully the other side effects are gradually wearing off. Before I got my first injection I was told it could take "up to a year" for the depo to get out of my system, that my bone density could be affected through prolonged use & that my periods would most likely stop while taking it. I was not warned of any other possible side effcts. I've also had a sore throat that flares up every few weeks & leaves me feeling exhausted by evening; I don't know if it's connected to the depo but it started a few weeks after my first injection...the doctor says it's a low grade virus that my body has been unable to shake off. F 30 15 months
12/6/2009
 5  To prevent pregnancy No or minimal periods. It helped reduce my cramps when I had a period. I seen all of these negative comments about Depo and I thought it was strange that I didn't have any of the mood swings or anything. I liked not having a period and no cramps. The only things I don't like is the possability of bone loss(the main reason I stopped taking it) and not being able to get pregnant right away. If it wasn't for the bone loss issue I would definately get back on it after we have another child. F 23 2 years
12/4/2009
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 4  Birthcontrol I haven't really had any side affects, i have been on it about 2 or 3 weeks. I'm normally moody and tired, i have lost weight though. I possibly have endometrios, it runs in my family, my doctor said that it seems to be the best treatment because it could get rid of it. Birthcontrol pills don't work for me, they make my period work and my cramps worse to the point that i can't even walk around at work. F 17 3 weeks
12/1/2009
 1  Regulate menstrual cycle Headaches, neck and back pain, achey joints, mood swings, 3 week long periods. I took the depo shot to regulate my periods. I was having a period every 2-3 weeks, and was told this would stop that. I have been having a period now for 3 weeks and have been having neck and back pain and headaches. I also didn't realize the risk of osteoporosis after being on the shot. After doing more research I will not be getting the next shot. I wish I would have researched more before agreeing to get it in the first place. F 32 2 months
12/1/2009
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 1  birth control headaches, backaches, vomiting constantly, vomitting blood, spittig up blood, aches everywhere, awful cramps, hair loss, took it four months ago only once and stopped taking it... still no period.And depression and anger. I don't reccomend anybody to take this shot. Although it's an upside that i didn't get a period for the first two months when i did it lasted for nine days... unusual for me. I vomitted blood and spat up blood and still am doing it. I feel depressed and my bipolar is worse. I did research and found out that this is most likely the cause to all of my problems and found out some woman are suffering infertility after getting the shot. My doctor didn't tell me ne of this would happen. Wish i did more research. M 20 3 months
11/29/2009
 1  Prevent Pregnancy Increase in migraines, weight gain (20 lbs), anxiety, spotting, acne, skin became oily I have been on it for 6 months. My next shot is supposed to be Dec 4, but I will not be taking it. I'm going back to old birth control. The weight gain didn't seem to bad and the acne could be cleared up with extra work in taking care of my skin; those were my thoughts after the first 3 months. I loved not having a period and not worrying about chronic yeast infections from the pill. Depo is so not worth it in the end. Our bodies just aren't meant to have something completely screw with our cycle like Depo does. After 6 months without a period, I began spotting out of no where. I have acne and have gotten 6 cysts in 1 month and have ingrown hairs all over my legs and have gained 20 lbs. I feel disgusting, not to mention the horrible anxiety I have been experiencing. I am a very strong person who has been through a lot and now I am terrified of everything and worried from the time I wake up to the time I go to sleep. Also, I have horrible vivid nightmares every night and migraines. Apparently my body is trying to tell me that something isn't right and it's obviously the Depo. I know it sounds like a wonderful idea, but it is not worth throwing your body out of whack. F 22 6 months
11/26/2009
 2  to avoid pregnancy depression>>>suicidal ideation, anxiety, change in appetite, mood swings, trouble sleeping, stomach pains While it was VERY convenient to just have the shot and mind my own business, it caused a lot of mood swings for me. I am already being medicated for anxiety and depression, so I assume that I was predisposed to the mood changes, but I noticed that my thoughts were extremely hopeless during the time when my cycle should have been going. My boyfriend noted the change in my behavior and told me to never get that shot, again....so I listened :) F 24 90 days
11/24/2009
 1  Birth Control hmm where do i start....mood swings, no periods, no sex drive, nearly ended my marriage, depression, weight gain, angry most of the time, low self worth.....the list goes on I started taking this jab in Apr 09. I went to get a smear test done after i had a baby and it was recommended to me. I should really have done reaserch but we usually listen to what doctors say because we expect that they know best. I've since had two more which totals 3 jabs in 2009. I was due for another end of October but after what i've been going through and the extra reaserch i've done i decided to stop taking it. Its been 3 months now and i'm yet to see my period. what scares me is hearing about the irregular bleeding after you stop it. Ive been home from work for months depressed. There was so much ( and still is) so much fighting and arguments in my marriage that at one point we talked about divorce. I just generally felt like crap and not myself. I thought this jab was perfect when i heard no periods and how well it works as a contraceptive but they don't tell you the side effects you have to do your own reaserch. I would NOT recommend Depo- provera to anyone. I will NEVER touch it again. F 25 5 months
11/23/2009
 3  No pregnancy Moodiness, anxiety, weight gain, fatigue, bruises at injection site It is great for people who do not have regular schedules and can not remember to take pills but there are a lot of negative side effects so I do not recommend for extended periods of time(under 2 years). For the first six months I did not notice any change but lately I have been irritated and sleepy a lot. I have also gained about twenty pounds, which isn't too bad because I've always been underweight. After eleven months of being on it I've noticed some spotting. The biggest problems for me are the fatigue and the anxiety, I am busy with school, work and a family and get regular sleep but it never seems to be enough because I am always feeling like I need a nap and always feel worried and anxious when there isn't anything wrong. I understand that this is different for everyone and hope you do too but I just hope that I can help another woman identify any side effects she may be experiencing and inform newcomers to the possible side effects. F 25 11 months
11/22/2009
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 3   RASH AFTER 3 YRS OF BEING ON THE SHOT. I DECIDED TO GET THE SHOT AFTER I TERMINATED A PREGNANCY. I WAS THRILLED TO NOT HAVE A WORRY OF BECOMING PREGNANT. THEN I HAD THE REACTION AND HAVE BEEN OFF OF IT FOR 6 YRS. I CAME ON HERE TO FIND OUT IF ANYONE ELSE HAS HAD IRREGULAR PERIODS AFTER BEING OFF OF IT TOO. WHAT I MEAN BY THAT IS...NO PERIODS AT ALL. SOME MONTHS. EVEN 2 MONTHS IN A ROW..? WHEN I DO HAVE ONE IT IS CLUMPY AND GROSS..NOT FLUID LIKE USUAL. I WENT TO THE GYNO AND THEY EXPLAINED TO ME THAT NOW THEY ARE SAYING THERE IS A TWO YEAR MAXIMUM FOR BEING ON IT... F 34 3 years
11/19/2009
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 3  Birth Control/Avoid Migranes Nausea, hot flashes, extreme anger (especially with my boyfriend), weird psychological episodes, weight gain (about 15 lbs), fatigue, lack of motivation, some acne episodes, a general overall feeling on 'unwell'. Basically, not feeling like myself. I cannot express enough how happy I am to have found this website. I was truly beginning to think something about me had suddenly gone wrong and that I was developing a mental disorder! Seriously! I have experienced many of the same side effects that most other women have on here, especially the hot flashes, dizziness, weight gain, fatigue and the psychotic episodes. I am normally a level headed person who is mature enough to handle most any situation. But since being on the shot, I started in May 2008, I have almost lost the ability to keep my cool! Especially when it comes to issues with my boyfriend of two years. It was recommended that I go on the shot because I was suseptible to migraines. The only thing the doctor told me was that I may gain weight as it increases appetite, and I would not have a period...yeah! NOT! I am due for my next shot this week, but I will not be getting it. I am going to go back on the regular 'ol pill. I am so upset with myself for not researching this drug sooner. I had no idea my physiological as well as psychological changes were due to taking this drug, not to mention the possibility of sterility! I feel hopeful about getting off it and getting back to myself again. I will try to update. F 27 1 years
11/18/2009
 1  Birth Control 60lbs of weight gain, loss of period completely, achy everything, sex drive was gone, after getting off the shot I boinked like a rabbit. I'm also concerned that I'm sterile now. I love that 10 years later I get the news that 2 years on the shot is more than enough to make people cringe. F 26 10 years
11/17/2009

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