DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control PAINFUL INTERCOURSE!! Continual spotting. Doctors do not warn of any side effects and it took 9 months and a referral to a gynocologist for anyone to suggest that the depo could be the cause of pain during intercourse. Last injection was 5 months ago, so far there's no change, do your own research! F 24 3 times
1/15/2007
 5  Doctors Surgery Small interests in sex at first but this is my second injection and in fine now. I have pcos and i find it helps me a great deal. I hae periods that go on for 3 months at a time and they are reall heavy. Now they have stopped and im great. F 23 6 months
1/10/2007
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 3  Severe Cramps I had a great increase in weight. In the matter of 3 months I gained about 20 pounds. I constantly feel tired and when I do any simple physical task I have shortness of breath. My sex drive has lowered dramtically to the point I just do not care. Although, I love not dealing with all the painfull cramps I just can not deal with side effects that this shot comes with. F 24 1 years
1/10/2007
 1  Contraception Loss of sex drive, severe depression, emotional numbness, Painful sex, lack of lubrication, lots of breakthrough bleeding, anxiety, weight gain, vaginal odor, fatigue, breast tenderness, joint pain, bloating, sore muscles, hair loss, abdominal pain, headache, nausea, acne all over my body, sweating, shortness of breath, blurred vision, chills, weakness, memory problems, and constant dark discharge I went to planned parenthood to get the Depo-Provera shot, and the clinician didn't even give me a pelvic exam! I had NEVER had one before, and she gave me the shot without examining me. Then she told me there were no side effects, just that it may cause bone thinning, and it will take 1 week to take effect. Within hours of getting the shot, my emotions were severely effected in a negative way, my body felt heavy, I was tired, and very hungry. The physical side effects wore off in a few days, but the emotional problems worsened. I was very angry, depressed, suicidal, anxious, and constantly on edge. After about a month and a half on the shot, I got a 3 week long period, and had deep brown discharge everyday for a month and a half after that. I didn't want sex at all, and even when I did sex was VERY painful throughout the three months on the shot. I am now feeling the 'detox' from being on the shot, and my anxiety is the worst its ever been!!! F 18 3 months
1/9/2007
 3  Endometriosis Weight gain, painful sex, mood swings, irritability, hot flashes As far as treating my endometriosis, this has been a miracle cure! No periods, no pain. After battling endo for upwards of 22 years, the disappearance of pain has been an unbelievable experience. However, I am becoming increasingly torn over the continued use of Depo because of my seemingly escalating array of side effects. I have gained 15 pounds in a year, I seem tired all the time, and sex with my husband of 20 years is so painful that I am avoiding it at all costs...very unhealthy for my marriage. I have 5-year old twins and a 3 year old so I can attribute some of my irritability to the general turmoil of dealing with a houseful of small children but I really feel that I am unrationally volatile in a way that I hadn't been before. I'm having serious doubts about my miracle benefits when balanced against my seeming costs. My pain treatment against my mental well-being and the effects on my family! I really don't know what to do. F 41 1 years
1/8/2007
 5  prevent pregnancy I have and had awful mood swings.I went without a period for three years.I have severe back problems but don't know if it's due to depo. I was on the depo for three years and I never had a period.The worst thing about that was the fact that I have the worst mood swings.I am happy one second sad the next and then I am mad.I cry a good five times a day and twice on a good day.I used to never cry about anything.I have been off the depo for almost a year my periods are regular again.But my cramps are so bad that when it is that time all I can do is lay in bed curled up in a ball and cry.I loved going for three years without a period but I would rather have then to go through the pain I do now. F 19 3 years
1/7/2007
 1  birth control, can't take the pill Fewer migraines, more headaches, black menstrual blood, increased fatigue I've been bleeding for the past two months. I was supposed to get my second depo provera shot on the 17th of November. My period started on the third of November. I did not get my second injection, as my doctor advised against it. I just want the bleeding to stop. It's black and thick and goopy and stringy. Too much information, but necessary. F 16 3 months
1/6/2007
 2  birth control light to medium bleeding for over a month, headaches, increased appetite, slight increase acne, tiredness, dizziness, mood swings. this is my first shot and these side effects are probably normal but theyre not worth it. its different for everyone. but ive been bleeding everyday since i got the shot along with the other side effects listed. i'm going on the pill after the 3 months is up. ive read so many better things about it and so many horror stories of the shot. please research it before considering it. it may work for you, it may not. F 18 1 months
1/5/2007
 1  Birth Control Extreme mood swings, depression, migraines, osteoporosis, cystic acne, hair loss, dryness I have not received an injection in 9 months. I have osteoporosis evidenced by a Z-score of -2.7 which remains constant after 2 dexa-scans. ***FYI*** Fosamax and other biophosphonates are not FDA approved for use in treatment of osteoporosis in pre-menopausal women. Not many HCP's are aware of this. My migranes have improved somewhat and may now be controlled with Excedrin Migrane rather than Zomig, which gave me palpitations. My mood swings began to decrease after 6 months. Looking back, my behavior while on depo was truly manic-depressive. My therapist referred to these times as "episodes", which included uncontrollable, unpredictable fits of anger and rage followed by extreme guilt, depression, and crying. Hairloss as subsided. My bathroom floor was always covered with my hair. The cystic acne covering my cheeks and forehead resolved 6 months after my last injection. Vaginal and skin dryness continues to be a problem. I do not recommend this medication to anyone F 36 10 years
1/2/2007
 5  birth control None Didn't get my period at all Loved it! Just to answer your question below...Took my first shot in November 2004.(I was 19) Took my last shot in August 2005, went back to get another in November 2005 but I live in Canada and the nurse told me that they are phasing out the shot, because of all the horrible side effects and she wouldnt give it to me. I did not have a period at all, from the moment I took the shot untill two days ago!(Iam now 21) 1 year while on the shot, 1 whole year+ while off the shot. I dont know if this was normal to not have it for a full year while off the shot!? Anyway I just wanted to say that this is the worst period I have ever experienced, and this is only the second day I have had it!! I used to have light flow and no cramps, and now this is a disgusting amount of blood.. and cramps that are making me actually throw up. I can barely stand! Can anyone help and let me know if this has happened to anyone else? Thanks F 21 1 years
12/29/2006
 1  Migraines, Birth Control Extreme decrease in sex drive, bloating, feeing hungry all the time, HAIR LOSS I was on the depo for around about 15 yrs. First thought it was brill but I didn't think my bald patch or mild depression and bloating had anything to do with it. Ihad a couple of breaks but my last shout was 3 months a go. I will never have another shot ever in my life. When I comb my hair it comes out and has stopped growing. no sex drive and acne whitch I never had before. I always rooted for the Depo shots BUT It's really not worth it. Trust me F 34 15 years
12/28/2006
 5  To prevent pregnacy Weight gain How long did it take for anyone to get their period after stopping the shot. Please e-mail me F 32 8 days
12/27/2006
 4  birth control negative sex drive, dryness during sex, weight loss (in beginning) With all due consideration that no drug is perfect, I loved being on Depo. The convenience of thinking about birth control only 4 times a year was great, however since I had no interest in sex anyway there was double the protection. Am going off of it now in hopes of getting pregnant in the next year or so. -- Also, I actually lost 15 pounds in the first year of being on it, four years later I'm at my pre-depo weight and maintaining with no problem. No problems with acne, depression, etc. Good luck! F 34 5 times
12/18/2006
 1  birth control INSOMNIA, anxiety attacts I started experiencing mild insomnia when I first got on Depo. My doc told me about the "new" depo and how it has less side effects. I got the "new" shot 2 weeks ago and haven't slept since. Also feel constant anxiety. I'm done putting hormones in my body. Going back to condoms. Hopefully it won't take a year to detox. F 30 1 days
12/18/2006
 5  to prevent pregnancy loss in sex drive, vaginal dryness, possible weight gain and acne I loved "the shot"! It is worry free and not having a period makes life a lot easier. I was on it for 5 years, went off to give my body a break, to get back to a normal cycle. I got my period two months later. The period I did have was unbearable. Cramps like I never had before I went on depo. I didn't get another period, because I found out I was pregnant three months after going off. I went back on after I gave birth. I have been on it for two years now and was due for another shot in November, which I did not get. Now my breast are tender and swollen. I took a pregnancy test and it was negative. After looking on the web, I found it might be a side effect of going off "the shot". Depo is great, but remember it is not "normal" not to get a period. F 24 7 years
12/17/2006
 3  birth control Viginal dryness (I'm 99% sure it's because of depo); aching and cracking joints and bones (I'm only 29, I feel like an old lady); difficulty maintaining weight; irrational moods. I have been on depo a few times for about a year each time and then come off it for perhaps a year. I do not have any bleeding with it which is one up side, the other up side is contraceptive. I'm convinced it's the depo which makes me feel depressed, angry and irrational, I wasn't like this before and I have no circumstances for feeling that way. I find I feel happier about 10 to 12 weeks after the injection and am seriously thinking of coming off it, and to hell if I get pregnant (although my boyfriend will not be pleased). I go to the gym 2-3 times a week, do yoga, and walk a lot. If I have a few days off from exercise my weight creeps up, even though I only eat 3 healthy meals a day and don't drink much alcohol. I'm also worried that if I stay on it for too long it will affect my fertility and I really want kids in about 2 years time. I have few alternatives: The pop pill gave me excrutiating breast pain, the mini pill cannot be prescribed because I have occasional migraine F 29 18 months
12/13/2006
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 2  Birth control severe acne, loss of libido, weight flunctuations I'm a new user, I'm due for my 2nd shot next week however I'm going to ask to be switched to something else. Ever since started depo, I've had a severe acne problem. I've never had severe acne, not even when I was a teen. I've spent a fortune in scrubs, lotions, kits, stringents, soaps, and everything else imaginable to clear up my skin without much luck. Also, Before depo I was a very (some would say overly) sexually active person and since taking it I've had almost no interest in sex. I haven't had any weight gain, but before starting Depo I was actively trying to lose and had lost 20lbs. I hoped if I just stepped up my weight loss routine the depo wouldn't effect it too much, but no such luck. I went from losing 2-3 pounds a week, to gaining and losing the same 3 pounds for 3 months. I was thinking about giving it another 3 months, but I just rather get something else and let all this stuff clear up. F 21 3 months
12/13/2006
 1  BC while i was nursing MAJOR weight gain, loss of sex drive I started the shot 2 months after I gave birth to my son. It was the only hormonal BC that is safe while nursing an infant. When I started the shot I was back to my normal weight, 120lbs(at 5'2 tall). After the first shot I noticed a slight but steady incline in my weight, then all of the sudden, almost over night I seemed to gain 25+ lbs. I know this isn't due to poor diet or lack of exercise. My husband and I are very active at the gym and eat very well. Recently I went to a new general practiner(we moved to another area) who seemed certain the weight gain was from the shot. He told me I didn't have a lot of body fat and that it was water weight that should come off once the shot wore off. My last shot was due over a month ago and needless to say, I didn't get it. Now I'm just waiting for my period to restart. My doctor told me once I get my period that's a sign the depo is out of my system. Although he did advise me it could take several months. F 26 8 months
12/12/2006
 1  help with heavy bleeding extreme weight gain, decreased sex drive, no lubrication, mood swings, constant bleeding I took the shot three times, and was told that it was my last option to control my extreme bleeding before going on lupron. I still wanted more kids, but was not told about the extreme side effects of taking this medication. Now I have been off of it for 6 months and have only had one light period over two months ago. I feel miserable, and don't know how long I can take this. F 25 9 months
12/11/2006
 5  As BC and for period relief Bone pain, muscle pain, acne, weight gain, fatigue, MS type symptoms. I think it makes for a horrible person to make fun of people who had bad side effects or call them crazy or names. All medicine effects everyone differently...so you don't know what you are talking about and just shouldn't speak. I loved the Depo...I was on it for 7 years. It was great for me. I had big problems with my period and it solved that. I too had the side effects and extensive testing to figure out what was wrong...and was told it wasn't the Depo. I weighed 94 lbs starting...went to 130 over the 7 years...thought it was age...stopped it and lost 30 lbs in 3 months! I feel better, but went right back to period problems. My 37 year old brother had a massive stroke a few months ago...so now they don't want me on anything. While I feel so much better off of it...I would have stayed on it if I didn't have that risk, as long as I knew what was causing my horrible problems...and now just happy to know I don't have MS! Some tests indicated I did...so there is medical proof of the changes it causes to your body. No one is crazy here...it is a massive drug...some can take it and love it, some cannot...and when you can't it is for real valid reasons. F 35 7 years
12/10/2006

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