DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Gained 30lbs in three months, cystic acne on face, back, chest, severe depression, no sex drive, hair growth on chin, PCOD, no period for a year after only one shot I think they should ban this drug. I know some people love it, but it has ruined three years of my life. I am just now getting over some of the side effects. I will sadly always have the PCOD now though. F 31 90 days
10/6/2008
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 1  birth control daily headaches, spotting for weeks at a time, very low sex-drive I cannot take anything with estrogen so I thought this was my solution to condoms. The side effects are so not worth it! I cannot wait until this medication gets out of my system. F 32 3 months
10/3/2008
 5  original reason - birth control I haven't had a period in 20 years. I did not plan on having children, and this was a blessing for me not to have to worry about pills. I started taking Depo approx 20 years ago - this is telling my age....I just returned from the Dr and he refuses to give me any further injections. His reasoning "you are too old and since there is no chance you can get pregnant, I will not give you further injections." I am completely frustrated. He further said that I have probably (PROBABLY) went through menopause so there is one more additional reason to not take the injection. I am 53, and I do not want to chance having periods, nor do I feel like he has the right to make that determination for my body. 20 years
10/2/2008
 1  birth control until essure worked hair falling out, extreme moodswings, anxiety, constant headaches, been bleeding for 5 out of six months. marriage ready to collapse. extreme moodiness, bodyaches, decreased sex drive. weight gain (15 pounds) hot flashes, i had my first injection the day after my little boy was born. I didn't sleep for three days after getting home. from that day i have cried at least once a day. my moods are constantly shifting and really hate what the shot has done to my previously happy home. I now feel like a crazy woman. I also feel very anxious for no apperant reason. I would not recommend this medicine to my worst enemy. F 28 6 months
10/2/2008
 1  To prevent pregnancy Severe mood swings, loss of sexual drive, hair loss I took Depo after my first child was born about 3 years ago and swore I would never take it again. However, in June I had another baby and because I was having the Essure procedure for permananet sterilization, my doctor insisted I have the depo shot again so I wouldn't get pregnant. I HATE IT! I am a total raving lunatic on this stuff. Everything my hubby does irritates me, I have no patience with my older daughter, I react negatively to things that I normally would be fine with. I also have absolutely NO sexual desire. I couldn't care less about sex or intimacy of any kind. My poor husband is tired of "pity sex". Once this shot wears off (my first one) I'm getting off this stuff and never looking back. Yeah, it's great not to have a period, but I'm tired of acting like satan all the time, and I want to feel desire again!! F 31 2 months
10/1/2008
 1  No more Children Hair loss, Extreme weight drop size 34 waist to size 20 waist in less then four months, Low iron, NON-STOP Periods, Acne, Headaches, and Very irratable, Extreme Period Pains. To each their own. I Will NEVER take it again I Now have to wear a wig. And It has caused me extreme pain. caused alot of pain with in my family. F 28 18 months
9/30/2008
 1  Taking it to prevent pregnancy HUGE loss of sex drive, huge appetite but can be controlled by a bossy b/f, terrible mood change as me and him used to get along but now experience fights EVERY night especially over the sex drive, I feel like crashing into a wall sometimes, very depressed, definately not acting like my usual spunky exciting self. Be careful girls as this can change your life after just one shot. Also heavy bleeding and spurts of spotting. I've been on Depo since April of 08 and I'm writing this on Sep. 29. 3 injections total and my boyfriend and I have come to the conclusion to discontinue its use as it has become detramental to my health and our relationship. Being smart about our sex habits and excercising safe sex has become the smarter option. If you want to talk about it then email me at [email protected] and remind me where you're from because I'll totally forget that I even posted on this site. F 20 6 months
9/29/2008
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 1  Pregnancy Prevention Discharge (sometimes yellow/green, sometimes brown). Spotting, loss of sex drive, mood-swings, bloating, dark spotting of my skin, abdominal pain, pain during sex. Depo is THE ABSOLUTE WORSE method of birth control. I do not recommend it to ANY women, ANY age. If you do not have at least 5 of the side effects, you will have a couple. It can take up to a year for the drug to be completely out of your system. There is no point to get it every 3 months if it stays in your body much longer. I regret ever getting the shot! I am hoping and praying every day that these side effects go away. F 17 3 months
9/29/2008
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 1  Stop excessive menstrual bleeding LOST MY MIND! Caused severe depression. Later, after taking the depo, here is what I learned: I took the Depo to combat my heavy periods. I had heavy periods because I had no natural progesterone in my body. I had no natural progesterone in my body because I put my body under major stress. The biggest mistake I made in my life was OVERDIETING. NEVER DO LOW CARB DIETING OR IT WILL MESS UP YOUR ENDOCRINE SYSTEM! I eventually healed from the depo. Also, don't take any so called bio-identical progesterone to counter the depo. ALL HORMONAL birth control causes some sort of whackadoodle change in your emotions and brain chemistry. Depo Provera is just the most dramatic, and most evil. Depo actually stresses out your system. You can actually have your stress levels tested by checking your adrenals. If you are looking to heal from Depo, you must heal your adrenals. It takes time; there is no magic elixir or potion or pill. You can expect to feel normal again in about 9 months to 18 months from the date of the shot. Get your adrenals tested: www.diagnostechs.com so you have a gauge on exactly how much your system is stressed out. F 39 90 days
9/28/2008
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 1  No Periods 40 LBS WEIGHT GAIN, HAIR LOSS, NO SEX DRIVE, MENTALLY UNSTABLE, MIGRAINES, JOINT PAIN, FATIGUE, INSOMNIA THANK GOD I AM 15 MONTHS FREE OF THIS POISON IT ALMOST RUINED MY LIFE. I CANNOT BELIEVE THAT I DIDNT COMMIT SUICIDE WHILE ON IT BECAUSE MY MOOD WAS SO UNSTABLE. I WENT ON IT WHILE I WAS YOUNG AND THOUGHT IT WOULD BE FUN NOT TO HAVE A PERIOD...WRONG!!!! I STILL DONT HAVE A REGULAR PERIOD TO THIS DAY.... DO NOT TAKE THIS IF YOU LIKE YOUR LIFE HOW IT IS NOW!!!!! F 24 4 years
9/26/2008
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 5  Severe Cramps No Periods! Possible weight gain but I have always been heavy. I had extremely severe cramping before depo, I would lose 2-3 days every month curled up in bed with a hot water bottle and as much IB prophren as I could take. The pain was so severe that I sometimes passed out. The doctors tried various things and one finally decided that Depo might work and it was a life saver. I had one doctor do some research for me on the bone loss over long term use and he found that the risk is in a small percentage of the population. This drug isn't for everyone but for some of us it is all that will work. Do be careful and pay attention to your body. I had an ideal reaction and now that I have decided to go off it to get pregnant, I am having some of the side effects that most people had going into it. Moodiness, long periods, hot flashes. Unfortunately the cramps are back as well. F 31 7 years
9/24/2008
 1  to not get pregnant depression, vomiting(not to mention the constant nausia that came with it),severe muscle spasms, worse cramps then before i was on it,cried for NO REASON, no sex drive, painful sex, headaches, no energy no matter how long i sleep, acne, 30lbs of wieght gain in 9 months! what the hell! dont ever take this shot, your doctor may sugar coat it as the best and most effective birth control out there, dont believe a word they say. the drug had made my life hell, with all the side effects that i got i may as well have been pregnant for the whole 9 months... i wouldnt recomend this drug to my worst enemy. im supposed to go in for a 4th injection next week but you can bet im not going to take it. the pain i had to go thru was NOT worth it at all. i would rather have another baby. the shot should be banned, it will mess you up! dont take it. F 24 9 months
9/22/2008
 4  Birth control Decreased sex drive, headaches, hot flashes. During the first year, there was a lot of irregular bleeding, but it didn't bother me because it was much lighter than my regular periods used to be. All in all, I think Depo Provera has been great. And having no periods anymore is WONDERFUL. My biggest complaint would have to be the decreased sex drive. There have been a few times where I was a month or more overdue for my shot, and suddenly I desire my husband again. I also have much more sensation during intercourse during these times. Depo has made me feel asexual. I have no desire. F 32 10 years
9/21/2008
 1  PMDD At first it was the miracle drug. I was no longer Satan before, during and after my period. But after 2 1/2 years I have realized I have had intense headaches, aches in my back,knees, ankles (I thought I had r-arthritis, but don't), constipation, rectal bleeding, loss of sex drive, loss of hair, depression to the near point of suicidal, moodiness and have became a new level of Satan all over. I did not gain any weight on the depo, but know women who have. Also the nurse that gave me the shot said she went nuts on depo. And I have a girlfriend who has a friend that is in a lawsuit due to the shot. I would try YAZ before depo. Although for a year I felt it was GREAT, however the effects after 2 1/2 years are NOT so great. It is not natural to not have a period, my body aches all the time and I seem to always 'feel bad' one way or another ... I dread the day my body goes back to normal and I have my first REAL period after 2 1/2 years. F 32 30 months
9/17/2008
 5  Birth Control I started getting this shot for birth control, but now I will use it for as long as my doctor lets me, even if I'm no longer sexually active. I'm sorry for everyone who had a bad experience with this shot because I honestly consider this to be the greatest decision I've ever made. I'm 24 years old and haven't had my period for 18 months, literally, no spotting or anything. I never get any cramps, bloating, etc. My sex drive has INCREASED. My appetite has not changed. And my boobs got bigger. No negative side effects for me at all except for a SLIGHT weight gain. I've been on this shot for nearly 2 years and I've only gained 5 pounds, but I also eat like a truck driver so I can't even be sure where the weight came from lol. Also, some of that weight went to my breasts. A 32AA is now a 32A. It may not sound like much, but to those of us in the itty-bitty-titty-committee (lol!) it's a huge difference. I have had nothing but a fantastic experience with this shot. I have read everywhere that you should not get this shot for more than 2 years as it MAY increase your loss of bone density. I'm approaching 2 years and my doctor is a bit hesitant to continue giving me this shot, but I will do pretty much anything to keep getting it. I'll tremendously increase my calcium intake, do weight-bearing exercises, etc. Whatever I have to do to keep getting it. It's fantastic. F 24 18 months
9/14/2008
 1  birth control EXCESSIVE BLEEDING! Hair loss, moodiness, low sex drive, fatigue, dizziness The only good thing I have to say about this bc method is that I did not gain weight, but I had every other symptom. I got my first shot in January and about a week afterward started spotting. I thought nothing of it, but I called my doctor after it had went on for nearly 2 months. Doc said that this would stop after the second shot, but instead the bleeding increased. I pretty much had a light to moderate period for nearly 6 months!!!! As a result I was always tired and started having dizzy spells. I was due to get my last shot in July and did not get it, yet I am still experiencing the dizziness. Now doc suspects that I am anemic. On top of all of this, I had excessive hair loss, which started out as more than normal shedding then increased to my hair coming out in patches. I had to get my past shoulder length hair cut to a short, spiky style, and my hair has still not totally recovered. Don't even get me started on the mood swings that ranged from me being extra sensitive to me bein F 25 6 months
9/12/2008
 1  Birth Control EXTREME wait gain, headaches, EXTREME moodiness, anxiety, joint and muscle pain, complete loss of period I started taking the Depo shot 6 weeks after my daughter was born, by my second shot I had gained 60 lbs (after losing all of it and being down to my pre-pregnancy weight), I had completely lost my appetite and was barely eating anything (small salads and stuff to keep food in my system), but gaining faster than ever before. My period stopped all together which I didn't mind, but I was still getting bad cramping. I got bad headaches and my joints and muscles hurt all the time, I had NO patience for my baby and my friends and family said I was very moody and on edge all the time. I stopped getting the depo shot before my 3rd shot, and it has been 2 years and I have only had my period once since then, I still get bad cramps and joint pain, I haven't been able to lose the weight even after following a strict diet my doctor put me on, My Doctor said there are steroids in the shot that I didn't know about before I started taking it, and that's why I had such weight gain. This form of birth F 23 6 months
9/12/2008
 1  birth control Really bad bleeding for 2 1/2 weeks, really bad lower abdominal pain, HUGE mood swings, angry ALL the time, the smallest thing sets me off, no sex drive AT ALL most of the time I don't even like my boyfriend to touch me, always seem to be bitchy when I try not to be its like i cant control it or do anything about it. It was a few weeks after i got the shot that I began to slowly change, and I feel like I dont even know myself anymore. I'm just so moody and bitchy all the time and that's not like me at all! I HATE Depo!!! I will never ever take it again!! I've had nothing but problems ever since I started taking it!!! Take my advice and do not take it. My sister warned me before I took it not to, but I didnt listen to because Im really bad about taking a pill everyday. Now, every day she says "I told you so!!!" F 22 3 months
9/10/2008
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 4  No more children for me! I first tried the Depo shot when I was 17 and went off it due to a constant period that last for 7 months. This time around was different...in the beginning I had the hot flashes, acne that wouldn't go away, nervousness, and headaches. I also started spotting the same day I got the shot..spotted for about 8 days. I had horrible mood swings and would cry for no reason at all. My poor boyfriend was getting frustrated with me. I told everyone I wasn't going to get another shot..it was horrible! The worst side effects lasted for about 3 to 5 weeks and I have had basically no side effects since then. I lost 11 lbs in the first three months. I have no period..no spotting either. I still have the mood swings, but I just try to laugh them off. I still cry a lot more than I am used to, but again I try to just deal with it. It's much easier on the Depo..no pills to remember everyday! I wouldn't trade it for the world! I just got my latest shot and there will be more to come! If I got through the side effects, you can too! You just have to want to get through it. F 23 3 months
9/5/2008
 1  birth control i THOUGHT that the only side effect was no period, which was awesome and why i stayed on it so long. now i look at what everyone has said and i realize that there are too many coincidences. the effects that i have in common with others are: unstable mood swings, feelings of depression, lack of sex drive, dryness, painful sex, horrible night swears. ALSO now have been diagnosed w/ OSTEOPENIA I feel sick to my stomach when I look at what everyone is saying and actually thinking that I could get away with not having a period for almost 10 years and not having other side effects. I have been diagnosed with osteopenia (low bone mass density, now at risk for osteoporosis) and ONLY found out b/c my Best friend was diagnosed and told me to get a test-not even my DOCTOR told me anything. i have been in denial and now i know that i not only HAVE to get off it to try to reverse the osteopenia, but hopefully I won't feel unhappy, unstable, and will get my sex drive back. PLEASE be careful of the side effects and don't get caught up in the thrill of no periods like i did. only take short term and/or if you are going to be sure to take the calcium supplements to make up for the calcium the depo leeches from you. this didn't work for me b/c the whole reason i took the shot was b/c i couldn't remember to take a little pill. . . F 27 10 years
9/2/2008

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