DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Heavy periods Weight gain (set on fast); irritable (and I was the easy going one!); dizziness; fatigue and a 48 day period (and counting) I was a bad patient. I should have read more about it but I was about to do the 60 mile breastcancer walk and suffered from anemia due to heavy periods. The doctor said this would work. I'm on day 48 of my period which started ten days after the shot. I am just waiting for the side effects to stop - I would never take this knowing what I know now. F 45 3 months
1/5/2009
 1  birth control headaches, SEVERE depression, weight gain, moodiness, loss of sex drive, no energy i have only had 2 injections but it has had its effects already. i have gained about 30lbs in the past six months. i have had thoughts of suicide to the point of cutting my self. my boyfriend bless his soul has put up with me but i know im damaging our relationship with all the highs and lows i go through everyday. i had seizure out of no where and my dr. contributes it to the shot. i had bad knees before the shot and now they kill me ALL the time. and the arm i get my shot in hurts in the muscle to the point that i need heavy medication to take the edge off. WOULD NOT RECOMMEND THIS TO ANYONE!! F 19 6 months
1/5/2009
 1  No peroid/no baby's INSANE WEIGHT GAIN I JUST TURNED 33 YEARS OLD AND WOULD NEVER EVER RECOMMENT THIS DRUG. I HAVE TAKEN THIS DRUG 3 OR 4 TIMES. THE LAST TIME I TOOK IT WHICH I STARTED IN JULY OF 07 I WEIGHED 110 LBS. I STOPPED TAKING DEPO IN MAY OF 08 I NOW WEIGH 150 LBS. I NEVER HAD A PROBLEM WITH MY WEIGHT BEFORE. I ALSO TRIED WORKING OUT EVERYDAY FOR THREE MONTHS AND DIDNT LOSE A POUND. I NEVER HAD THIS PROBLEM BEFORE WHEN I GOT THE SHOT. LET ME ALSO SAY THAT GETTING BACK TO "NORMAL" IS NOT AN EASY THING. I'VE NOT HAD A SHOT SINCE MAY OF 08 AND IVE HAD TWO PERIODS SINCE THEN. CRAZY!! F 33 6 years
1/4/2009
 1  not wanting to get pregnant loss of sex drive, nasea, horrible stomache ache, depression with suisidal thoughts, horrible mood swings, dissy, head aches, ect i only took it a few weeks ago. i didnt find out how bad it was until the same day i got the shot and one of my friends said she got a stomache ache from it. well she was right and more. my boyfriend has to deal with me being happy one minute to yelling at him for no reason the next. he also had to sit there and listen to me say oh life sucks, why am i alive, stuff like that. if i could go back, i would never have gotten this shot. im going to not go back for my next one in march. i hate the feelings of mood swings, stomache aches so bad i just wanna puke. i have like no energy. my boyfriend noticed that im not into sex as much as i was before. THEY SERIOUSLY NEED TO TAKE THIS OFF THE MARKET!!!!! also my boyfriends mom said she has known people on it, and she never heard a good thing about it... F 14 3 weeks
1/4/2009
 4  Don't want anymore children I've had some bleeding and spotting but only been on the shot for less then a month and already it's slowing as far as the depresson and such nothing my sex drive has increased and my boyfriend loves it, no dryness as for the spotting and sex it's hardly an issue. So far this drug has been great no weight gain no urges to eat my doctor told me the drug does not put weight on food does as he knew this was one of my main fears. As far as mood swings or depression not at all I think some people are blaming the drug for other issues in their lives. My sex drive has increased and I can't get enough so I hope this helps not all people have a bad experience with the shot. M 37
1/3/2009
 1  Out of control periods Mood swings, depression, anxiety, loss of sex drive, affected a good relationship, weight gain. This drug seems like it is so wonderful but it really isnt, i became a monster and pushed a really great person out of my life due to this drug, ruined my friendships and work and to add insult to injury i gained weight, had thoughts of suicide, wasnt interested in sex, and had many fits of rage (including when i was driving). NO ONE SHOULD EVER TAKE THIS DRUG IT SHOULD BE TAKEN OFF THE MARKET!!!! F 1 years
12/31/2008
 1  Doctor recommended it for endo. I have endometriosis and two doctors tried to push this and Lupron on me after having laparoscopy surgery to keep the endo from coming back. It makes me sick reading how many of you had to go through this suffering. Before going for the injection, I researched this "medicine" and read this site and talked to Depro patients, and I chose to listen to my body and not take it. I am 26 years old and had bad side effects from birth control pills in the past. The doctors wouldn't listen to me and told me I "have to" go on this but I didn't. Doctors are pushing this on people because they get a large cut from the drug companies. It's a sad world we live in. F 26 0 days
12/30/2008
 1  prevent pregnancy LOSS OF SEX DRIVE- I don’t even want my bf near me MOODINESS everything and everyone annoys me LAZINESS- all I want to do is lay down, watch TV and sleep, and having an 18mon old this is hard I want to do stuff with him!! NO motivation!!! RAGE- out of nowhere! DEPRESSION- I just fall in and out of this SAD- just feel sad at times VAGINAL DRYNESS- I’ve never needed lube until now! JOINT ACHES- I feel as though I have arthritis! BACK ACHES- it’s unbearable STOMACH ACHES & CRAMPING- especially when the shot is due again I get really bad cramping, esp. after urinating to the point it makes me want to cry, its feels like your uterus is contracting when you are giving birth WEIGHT GAIN- none of my jeans fit, they are all tight, even though I have not been eating because: LOSS of APPETITE- I’m not hungry, then I am, then I’m not, then I am... its driving me Nuts!! Since taking the shot it has TRANSFORMED ME my boyfriend is the sweetest guy you will ever meet but yet I find ways to be mean to him, for NO REASON! I don’t know where it comes from and I CANT STOP the anger! everything irritates me, I have not felt the same since I have taken it, and it feels almost as if I need it now, last month I went to PP and told them my side effects and how I was having severe stomach pain and I wanted to know whether that was normal, they said that it was just because I needed the other dose to help with the pain, and I just wanted to be rid of the pain, and is why I decided to take the next shot, that was the second time, now again I have 2 weeks until my next shot is due and I am experiencing the same excruciating pain, it is almost unbearable, and it is especially worse right after urinating, it feels as though my uterus is contracting, and quickly after I spot blood. I’m afraid for my relationship with my boyfriend because to be honest I know F 23 6 months
12/29/2008
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 1  Birth control Extremely long-lasting period!!! Mood-swings, loss of sex drive, weight-gain! I have had 3 shots so far. At first I was satisfied with it, but after about a month I took my fist shot I had my period for 6 weeks. My doctor said its because I had stopped breastfeeding, so I thought that made sense. 2 days after I got my third shot, here comes my period again, 24 days and still going!!!! I wish I knew about these side effects, because they seem to be so common. Also, I lost my sex drive completely! F 23 7 months
12/29/2008
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 1  birth conrol Depression... constantly felt sad and unmotivated, which is very unlike me. I am more irritable than usual and it has affected my friendships and relationships. No other birth control has had any effect on me whatsoever. I am going off it next month and can't wait to be myself again. F 24 5 months
12/29/2008
 1  birth control Severe headaches, weight gain, irritability, severe depression, suicidal thoughts. While not having a period is nice, it isn't worth all of the other side effects. I have had only two injections so far, but I've already gained 10 pounds. This drug has nearly ruined my relationship - it destroyed my sex drive. I've had headaches since I started the shot and they have been most intense the day of and the few days following the shot. This drug has also triggered depression and suicidal thoughts. I spoke with my doctor about the lack of desire to have sex, as it was becoming an issue with my fiance. She assured me that although this is a less common side effect it should go away with the second shot. Well, the lack of sex drive hasn't gone away and to top it off my mood swings are out of control. I have been severely depressed and lately have been having suicidal thoughts. I will not be getting my next shot. F 28 5 months
12/29/2008
 5  birth control slight weight loss, period stopped, acne cleared I liked Depo while I was on it, but missed appointment and discontinued using it because am no longer seeing anyone. It took just over 6 months after discontinuation for my period to return. My acne got worse again only about a month after discontinuation. F 20 6 months
12/28/2008
 2  prevent pregnacny I was on the shot for 6 years and than decided to stop taking it because of people telling me it was not healthy to not have your monthly cycle. I got back on the shot a year later and it has been hell on earth. The brown discharge with foul odor is horrible. I want the spotting to stop. I did not have these problems when I was on it the first time. I have never had problems with acne and now it is out of control. My attitude is what you would have to call poor. I am irritable and quick tempered now. I have one more month to go and I am not getting the next shot. F 23 2 months
12/26/2008
 1  Birth Control I started Depo about 3 years ago. I gained a total of 80 lbs over the last 3 years. I never had a period, which was great, but I still had terrible mood swings and etc. I stopped taking the depo shot about 6mos. ago because I became concerned that I wouldnt start a regular period. I have not had a period in the last 6 mo and have gone 9 mos since my last shot!! STILL NO PERIOD~!!! I wish my doctor would have told me it can take up to 18MONTHS to start you period and that is IF you body starts to regulate!!! Not to mention the fact that NO ONE told me it effected your bone DENSITY!!! I DO NOT RECOMMEND THIS TO ANY WOMAN THAT HAS A BAD HISTORY OF BONE ISSUES OR TO ANYONE THAT WOULD LIKE TO HAVE FUTURE KIDS~~!!!!! F 19 3 years
12/26/2008
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 1  to control heavy periods intense bleeding during sex, near-constant spotting, excessive perspiration, weight loss (i went from 160 to 129- the only side effect i was cool with). it was never proven to be related, but i know deep down that it had something to do with needing my gallbladder removed at the age of 16. ANYTIME I HEAR OF SOMEONE TAKING THIS RAT POISON IT MAKES ME SICK TO MY STOMACH. this drug made my life A LIVING HELL FOR TWO YEARS, AND EVEN NOW, 5 YEARS LATER I AM NOT BACK TO NORMAL. While on it i developed vulvar vestibulitis, which a specialist linked directly to this poison. for over a year my vagina felt like it had a constant yeast infection. sex was impossible. after i saw several doctors and finally a specialist, i was placed on hormone therapy for six months. Depo had basically given me menopause at the age of 16. i had to go see a physical therapist because my pelvic muscles were constricted from being in so much pain. i still have recurring vaginal dryness. im 21, but i feel like im 50. please, PLEASE ANYONE WHO IS READING THIS DO NOT INJECT THIS POISON INTO YOUR BODY! THIS COMPANY NEEDS TO BE HELD ACCOUNTABLE F 21 180 days
12/25/2008
 2  birth control weight gain , headaches, long periods F 20 2 months
12/24/2008
 1  prevent pregnancy, regulate period Mood swings, backaches, headaches/migraines, loss of sex drive (completly), vaginal dryness, increased acne, loss of motivation, loss of energy, hot flashs, depression/thoughts of suicide, foul odor, no period of 1st 2 months then a constant 4 week period and counting... I got this shot because it was one of my only options (due to my history of headaches), but it is been the worst choice I could of made. My headaches have worsened (I had 5 in one day; including a migraine). I would never recommend this to anybody. I've never felt worse in my life. F 19 3 months
12/23/2008
 1  to prevent pregnancy at 15 weight gain, bad headaches, mood swings, nausea, no period, tired and lazy all the time...no energy I would not recommend anyone to take this shot!!! I was 15 when i started taking this and im almost 20 here in a few months. I have my life together and now want to concieve a child with my fiance. Ive been off of this shot for a little over a year now, I am getting my period once every few months for like 3 days. If your on it you should get off it now...this shot ruins your body, and I was just being stupid at a young age. F 19 2 years
12/22/2008
 4  dont want kids or my period Slight spotting a cpl weeks after my first shot. Some moodiness and emotional changes but not bad. I havent been on depo long but so far im liking it. My sister has been on it for years and has never had any problems these other women have had. 1st of all, it can make you gain weight...IF youre not active. All birth control puts you at a higher risk of a stroke. And some of you need to give it more time. Its a new thing for your body not to have its period every month so you cant expect NO period right after you get the shot..give it a little time. It seems like some of the symptoms these women put have to do with something else and not the shot. I agree it can cause vaginal dryness and loss of sex drive..but there are ways around that. I like the shot and will continue to use it. F 24 2 months
12/19/2008
 2  to prepare for Essure procedure constant spotting about three weeks after taking 1st shot I had used Depo Provera when I was in my early thrities with wonderful results. The one down side was when I stopped the shot, I had cramps so bad I ended up in the hospital. That should have been a sign however I am not interested in having more children and began the process for permanent birth control which involved using some type of hormonal assistance. I never remembered to take BC regularly so I figured the shot was a safe option. Wrong answer. I have been spotting everyday since October 29 that approximately 54 days just shy of two months. So I accomplished my goal permanent birth control because I am not comfortable having sex while I continue to "adjust". Hopefully my doctor and I can come up with a solution short of a hysterectomy to stop the spotting. F 44 80 days
12/19/2008

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