DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control I had weight gain and severe mood swings. I had no sex drive at all and extreme dryness if I did try to have sex. I quit taking depo about 1 year ago and am finally beginning to be normal again. I managed to ruin my relationship with my boyfriend because of my lack of sex drive and my anger. Luckily he came back after I got off the depo. I wouldn't recommend this to anyone. F 43 5 years
6/8/2008
 5  birth control and regulate period none bad.. i havent had my period in 4 years but i like that.. other then that nothing. my 48 yr old mum uses it to.. she has cancer and was getting heavy periods so tried it cause it was an issue she didnt need on top of everything else.. we are both really happy with it F 22 4 years
6/6/2008
 3  birth control mood swings, headaches I've been on this for almost a year now. And until recently have had no complaints. I've recommended it to friends. Latley, however, I've noticed I cry all the time over things that shouldn't bother me. I'm starting to get headaches for no reason. F 19 10 months
6/6/2008
 5  Heavy periods w/ bad cramps Minor headaches, weight gain, slight loss in sex drive. I got put on Depo Provera when I was 15 years old. I had extremely bad periods and they put me through rounds of different birth control and other medications and gave me depo as a last resort. I absolutely love it and feel it has been a big life saver. It does work differently for everybody but I feel a lot of people blame other symptoms on depo that are not even related!! I did experience some minor headaches and then realized a lot of it had to do with my eye sight going bad, once I was off depo the headaches continued until I had an eye exam....I did experience a little weight gain which I learned to control by eating better and exercising regularly. I had a slight loss in sex drive but I just took a medication that helped fix that because I pretty much require Depo to function... It is recommended to take breaks every 2 years from it and during that year break I am so miserable my periods pretty much stop my life and I am bed ridden. Nothing else works for me, I can pop heavy pain F 23 9 years
6/4/2008
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 5  birth control I don't get regular periods which I think is great! I do get some spotting though, but its not that commen. spotting can be frustrating though, it will last for a few hours and go away but then come back the next day or day after. Also spotting occurs after a lot sex sometimes and often occurs after a shower(?). I did have one time where I had a period for a month though, which was horrible. The doctors said it was just a "cycle of bleeding" and offered no relief. Besides that I never had real serious side affects, headaches were common at first but went away with time. I also LOST WEIGHT on depo... I was 185 when I started 2 years ago and now I'm 140, but this may be due to other factors as well, I'm just trying to point out that I never had the weight gain that some women complain of. I like depo, its very easy to manage and the issue of BC and pregnancy isn't constantly lingering in my mind. I don't have to remember to take a pill everyday which I think is great for people on the go. Every 3 months I just have to take 30 mins to go to the clinic and get the shot. Its great! F 18 2 days
6/4/2008
 4  as a method of birth control My side effects were as follows: no period, increased appetite, a lot of weight gain, emotional, tired, decreased self lubrication, lack of energy. All in all it was a great method of birth control for me at the time. I was getting the shot for 4 years and 7 months before going off for 10 months. I got one more shot and shortly after that I got married and we are wanting a baby so it has now been 9 months since that shot and I just had my 2nd period. I don't know what other "long term" side effects. I had a bone density scan done 2 years ago just to make sure I hadn't had any loss and things were fine. I am now just waiting to get pregnant. F 30 5 years
6/3/2008
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 5  Birth control Gained about 15 pounds, no period, stronger sex drive I gained about 15 pounds but with diet and exercise lost 30! No period except for about 2 days of spotting every 3 months. Sex drive seemed to be at least twice as strong. I LOVE DEPO. <3 F 20 2 years
5/29/2008
 5  it helped stop cramps hot flashes it worked for me it stop my cramps and my periods. and as an athletic person it was very helpful. stop blammimg the docters they tell u the side effects and u chose to take it. everybodys body takes the drug in a different way then others. im just glad it helped me but i will be coming off to let my body cleanse itself. F 27 13 years
5/27/2008
 1  Contraception EXTREME mood swings, anger outbursts (ruined my marriage from it), crying for no reason, depression, felt like i was loosing my mind, anxiety, no appetite. My doctor recommended it after a miscarriage, and within the first 3-5days, i had extreme anger outbursts and felt like i couldn't control anything and was loosing my mind! I would definately not recommend this "drug" to anyone. Any other form of bc but this! This is absolutely horrible, and doctors need to describe the side effects in greater detail rather than telling you that there isn't many except for weight gain, acne, and body adjustment! F 24 2 weeks
5/22/2008
 1  birth Control NO sexual drive-headaches-back/neck problems-rage-depression-weight gain-night sweats-heavy sweating during activities-nausea-cramping you name it.... However - I contributed the majority of my symptoms to depo for years, so did my doctors, even when new symptoms came up such as sleeplessness but constant major exhaustion, heart palpatations and major hypertension. Over the years I would gain more symptoms and complain to my doctor but it was ALWAYS blamed on the depo. See, after giving patients like my self, a 99.9% effectiveness, the doc has a hard time convincing them to try a different route. I would have Panic attacks BEFORE I started taking it because I was literally afraid of getting pregnant again....I have been on the depo for more than seven years and was just diagnosed with GRAVES DISEASE - multiple tests were done to confirm. My symptoms worsened dramatically to include the inability to concentrate, deal with situations that arose with my children/husband, I began to sweat profusly, night and day, I experience heart palps, dizziness, nausea, severe migraines and I was so hyper I would scream at anything that had a mou F 34 8 years
5/20/2008
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 5  Migraines & Contraceptive Did not have a period while on depo. Didn't notice significant weight gain but had a hard time maintaining current weight. I originally started taking depo because I needed an estrogen only method since the combination pills give me migraines. I switched onto depo and had NO headaches! And, I didn't have a period, which, while some people prefer to have one, I was fine to be hassle free. And only a $15 office copay every 3 months vs. $25/mo for the pill was great. The only down fall is that I could only be on it for a max of 2 years due to the potential for bone density loss. This really is a drug meant for younger women. I'm switching to the mini pill (Micronor) now, so we'll see how that goes. I hope I have a positive experience. F 29 1.5 years
5/9/2008
 3  regulate period/birth control severe weight gain, fatigue, irritability I started this shot a year ago because my doctor was concerned about stroke because I get migraines and smoke. At first, it was great, I lost ten pounds, felt wonderful and had an amazing sex drive. I still haven't had my period since the first shot, but after six months on it I started to gain weight and it hasn't stopped! I went from 150 pounds to 185 in five months - none of my clothes fit, I'm crying all the time about silly things, I'm way too tired to have sex or spend time with my fiancee, because all I want to do is sleep. I'm going off it after one more shot and going with a diaphragm or another non-hormonal BC because it is just getting to be too much. After a decade on hormaonal birth control, I don't even know how my body is normally supposed to act! F 25 1 years
5/8/2008
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 3  Functional Ovarian Cysts Depression, Anxiety, Rage, Antisocial Tendancies, Joint Pain, Muscle Aches, Insomnia, Nightmares, Night Sweats, Hot Flashes, Fatigue, Loss of Interest in Daily Activities, Cramping, Aching Breasts, Constant Spotting between LONG Periods, Acne, Hair loss, Nausea, Head Aches I took this six years ago for a year with no serious issues. Knowing the risks, which to me outweighed the benefit. I have a problem with functional ovarian cysts which was quite horrible with constant bleeding and debilitating pain at times. Only treatment option I was offered was the pill or the shot. I didn't think the pill was a good idea after being on it for 10 years of my life and the shot seemed too dangerous. I lived with them for two years before finally out of painful frustration going on the shot. My pain and period went away almost immediately, the cysts shrunk and went away, but lost sex drive and was told by my ex and friends that I was moody and irritable. I didn't believe them. After going off, I had no problems until two years ago the cysts came back. After about six months of "waiting to see" and getting worse, I got back on it. My periods have never stopped and I was constantly spotting icky brown or red clots until my fifth shot which was in Jan F 36 1.5 years
5/8/2008
 3  Stop periods It stopped my periods, all right. It also made me gain 20 lbs. Headaches. This is a very convenient form of birth control but for me the side effects outweigh the benefits. Despite being very active, I have gained 20 lbs. in two years. I also get headaches, which I rarely had before going on this medication. F 38 2 years
5/8/2008
 2   hot/cold flashes, anxiety, possible hair loss At first this seemed great, no pills, no ring, no condoms, sex whenever.. then the hot/cold flashes started.. completely ridiculous, the bf hated it because my temperature would change every 5 minutes, he couldn't even touch me, I was too hot, the people at work got pissed I constantly changed the thermostat, whatever, I could deal with that.. 2 months in.. I'm to the point where committing myself to an institution is not looking like a terrible idea, I feel psychotic all the time and it's really taking it's toll on my relationships. There is a constant feeling of hopelessness as well. I can only assume this is from the Depo.. I have 2 friends that are on it and they don't have these issues so I guess it works for some.. not me though. F 25 2 months
5/8/2008
 1  Birth Control Weight Gain,Depression, Mood Swings I STARTED TO TAKE DEPO BECAUSEE I WAS STARTING COLLEGE AND DID NOT WANT TO GET PREGNANT. FOUR YEARS LATER I GAINED 30 POUNDS. I DONT ENJOY SEX AS MUCH AS I USE TO. I DONT GET WET LIKE BEFORE. IT IS DISGUSTING. I AM LUCKY THAT MY BOYFRIEND UNDERSTANDS OR ELSE I WOULD PROBABLY BE ALONE. I WANT TO HAVE CHILDREN SO I HOPE THAT WHEN I START TO TRY I AM ABLE TO. TO ALL THOSE WHO DONT HAVE SIDE EFFECTS NOW......... JUST THE THOUGHT ALONE OF SUFFERING WITH WHAT WE HAVE BEEN THROUGH SHOULD TURN YOU OFF FROM THIS PRODUCT. I WISH WE COULD SUE BECAUSE DEPO ALMOST DESTROYED MY LIFE F 25 4 years
5/5/2008
 1  contraceptive irregular bleeding, EXTREME PAIN during intercourse, vaginal dryness, migraines, insomnia, panic attacks, slight weight gain I've only been on this medication for 6 months and cannot wait until it's gone from my body. I wish I never took this stuff. Sex started out as being just uncomfortable as I couldn't become lubricated and was extremely dry... then that problem went away, except sex has become SO extremely painful for me. My vagina feels like it has open wounds and is ripping apart during sex, I've been to the doctor numerous times and they can't find anything wrong with me. Now I know it's Depo, and after reading all these reviews I can attribute my awful migraines that I've been getting everyday, random panic attacks, and insomnia... ALL to Depo. STAY AWAY FROM THIS MEDICATION. It should be taken off the market. Please email me if you want to talk about this more or have any questions. F 21 6 months
4/28/2008
 3  pregnancy prevention loss of sex drive;breast tenderness; weight gain (from 130 to 165);cyst-like weaps in vaginal area; unbalanced Ph (sweaty underarms and vaginal area; alot of water retention in legs and feet;mood changes; headaches; weak/painful joints This is a great product but is definitely not designed for the long term! stop it all together. I was due to recieve another injection in February but i decided to stop getting them.I was taking birth control pills prior to getting the shot because i was having problems with ovarian cysts. My doctor suggested that since i began having problems with the pill that i try depo. He did warn me about the risk of loss of bone density and i knew that i didn't have strong bones, so i took a risk. I was willing to work around the other changes that my body was experiencing but the weight gain has gotten out of control along with the decreased sex drive. It has truly caused a problem within my marriage which is not cool.I was relieved to see the postings on this site because im not alone. Alot of women are or have been experiencing the same side effects as i am. I thought that the changes i was going through were due to age but i see that is not the case. My recommendation to anyone F 29 14 months
4/26/2008
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 1  Birth Control Extreme fatigue, loss of sex drive, irritablity, mood swings. I have been on this for at least six years and every year I went to the doctor complaining that I was ALWAYS tired. I got checked for everything you can think of and yet nothing. I was clueless to the fact that the shot could be doing this but after reading all these other comments I realized im not crazy. I only wish that my doctor suggested this...I went to three different doctors and non of them said it was due to the shot. How clueless are doctors? My shot is up in May and I really feel like getting off of this will change my life completely. I really hate being tired and irritable. People eating chips drives me crazy!! I would recommend not taking the shot, I feel like it ruined 5 years of my life. I never want to do anything, I always want to take a nap and I don’t care to have sex. Low sex drive can ruin relationships. F 22 6 years
4/25/2008
 2  Endometriosis/Birthcontrol 50+ lbs of weight gain!!! Moodiness, irritability, cramps, fatigue. I am a VERY active person. I have played college field hockey at a divison 1 level, so the work outs and dieting are very strict and hard. While I was on depo for two years during this process, I lost no weight at all, in fact I gain 50+ lbs. I have been off of depo for over 5 months and am having a very difficult time losing the weight. The doctor informed me that I may gain some weight, thinking 5 or ten pounds, but not 50+. Do NOT take this drug, not only has the weight gain affected me tremendously, but since being off of it my periods are VERY painful and my body is still suffering from other side effects of the drug. F 21 2 years
4/21/2008

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