DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Heavy bleeding with the first cycle (5 wks out of the 3 months), depression, irritability, no sex drive, acne (last cycle), hair loss Was introduced to Deprovera by my Ob-Gyn most likely bc I was a young girl (22) and wanted me to be on a birth control and that didn't needed to be taken daily. "more convenient" for young girls that can't comply w taking a BC pill daily. Liked the idea of convenience at the time, however, once I started experiencing such side effects that were affecting my life on a daily basis I researched the drug more and came to find out that other women were going through similar circumstances. I would not recommend this BC to anyone! They shouldn't even have it on the market!!! I can't wait to be me again and acne free! F 23 3 times
1X O
1/18/2011
 5  Birth Control No period I started Depo back in highschool because I had really bad periods and the doc suggested this would help. I have had never had an of the bad side effects described by many. I did not have my periods throughout the 11 years, unless I took a break from the shot. I took a one year break about 3 years ago, just to see if my body would "act" normal, and it did. I had normal periods and was just fine. I just recently got engaged and now want start trying to have a baby after the wedding this year. So I decided to get off of the shot and get on regualar bc pills. I am experiencing sore breasts, but thats it. The first 28 days I had a period for 3 days normal bleeding and im on my second month now. So I would recommend this to people who dont experience the side effects. I have been lucky I guess, because ive never gained weight, never had mood swings, never had acne and never had a lowered sex drive. I loved it while I was on it, and although I might never go back on it after I finish having kids, I would still recommend it to anyone who wants an effective bc that is easy to use. F 29 11 years
1X day
1/17/2011
 1  birth control nausea, headaches, fatigue, bleeding I only got 1 shot under the insistance of the dr. after having a very premature baby. 6 months later I have bee bleeding nonstop for 7 weeks with constant nausea. So hard to care for my family like this. Those who are so happy with depo....wait until you try to stop taking it. F 35
1X O
1/17/2011
Email
 1  ease of use, the idea of no period Anemic,period with no end,slight weight gain,tired all the time,loss of sex drive,headachs At first I loved this form of birth control,and then the bleeding started,for 6+ weeks now I have been bleeding non-stop some days light(brown)and the next heavy bleeding,cramps come and go but are more like contractions than cramps,I actually went to the dr because I was so anemic(dizzy almost to the point of fainting and vision would go black)I have headaches that just won't go away,can't even tell you what desire to have sex is anymore(this is getting worse with time)and all I want to do is sleep.Which is not me.Don't want to scare anyone but please do your homework before getting this shot.Will not continue use and hope that this crap leaves my body quickly.Very diaspointed I got this form of BC. F 27 3 months
1 shot 1X O
1/17/2011
 1  Birth Control I had Depo-Provera SubQ,which claims less weight gain.This version is injected into the muscle.I only had 1shot into my thigh muscle.My muscle has since degenerated.I now have a large dent the size of a 50cent piece in the front of my thigh,I am super petite,only weigh 110,no cellulite.The 1st few wks after injection I had nausea, migranes, vomiting every morning,decreased sex drive,body acne,severe mood swings.Into 2nd mnth all symptoms remained except the nausea. Due to losing my thigh muscle,giving me the appearance of visible cellulite on the front of my thigh I did not want to continue use.When I did not receive my 2nd shot my withdrawl symptoms were worse than the ones I felt when I started.My migranes moved to the back of my head and top of neck.I gained weight,increased 2pant sizes just to be able to zip up.I have severe bloating in lower abdomen, bubbling feels like kicking,acid reflux,frequent urination,excessive discharge, extreme fatigue,body acne, angry, impatient, increas I had Depo-Provera SubQ,which claims less weight gain.This version is injected into the muscle.I only had 1shot into my thigh muscle.My muscle has since degenerated.I now have a large dent the size of a 50cent piece in the front of my thigh,I am super petite,only weigh 110,no cellulite.The 1st few wks after injection I had nausea, migranes, vomiting every morning,decreased sex drive,body acne,severe mood swings.Into 2nd mnth all symptoms remained except the nausea. Due to losing my thigh muscle,giving me the appearance of visible cellulite on the front of my thigh I did not want to continue use.When I did not receive my 2nd shot my withdrawl symptoms were worse than the ones I felt when I started.My migranes moved to the back of my head and top of neck.I gained weight,increased 2pant sizes just to be able to zip up.I have severe bloating in lower abdomen, bubbling feels like kicking,acid reflux,frequent urination,excessive discharge, extreme fatigue,body acne, angry, impatient, increased anxiety (mood swings),sweating then overly cold,boobs are bigger and if you squeeze them they have fluid like I'm pregos.This is a horrible drug!The fact you cannot find the real side effects or real withdrawal symptom details,nor how long these symptoms last makes it very misleading.I haven't even found a blog which discusses Depo-SubQ.This drugs negatives greatly out weigh the positives, definitely choose another method for birth control. DO NOT TAKE THIS DRUG!!! F 31 3 months
1X AN
1/17/2011
 2  birth control, reduce symptoms Rare light spotting, no cramping, weight gain, decreased ability to be aroused/stay aroused, harsh effects after going off shot Started using it for birth control and to reduce or eliminate my horrible cramping. I was attracted to the concept of 1 shot every 3 months. After the 1st shot, my periods started getting lighter and eventually stopped. I had no cramping which was a wonderful plus; however, after my 2nd shot, I noticed a decrease in my sex drive. I had to start using lubrication, but even with that, halfway through intercourse I would be dry again. I eventually ended up completely losing any desire to have sex. I gained 8-10 pounds mainly due to the occasional heightened appetite. I waited a month before I received my 3rd shot to give myself a little break. After the shot, I was on my period for 2 weeks and spotted off and on during the entire 3 months. My sex drive was non-existent and my poor boyfriend had to suffer. I finally decided to not receive a 4th shot which was supposed to be in late August 2010. 2 months later, I thankfully had my sex drive back to "pre-depo"; but, I developed pregnancy symptoms (lightheaded, nausea, tender breasts, etc) for months. I didn't receive a period until late October and it lasted for a month, first with old blood, then new blood. First week of December I had another period (7 days) then the day after Christmas I had a period (10 days). Now I am on my period again and it's very heavy. I'm still bleeding dried blood and new blood... I would not recommend this to anyone... not even my enemies... F 21 9 months
1X AN
1/16/2011
Email
 1  prevent pregnancy, bad periods 75 pound weight gain,high blood pressure,severe depression/anxiety,irrational thinking,vaginal itching, complete period loss,hot flashes/night sweats, back and body pain, oily skin, acne,extreme darkning of the skin esp. on my face,crazy mood swings,hair loss,breast tenderness and enlargment,bloating,migraines This drug should be taken off the market!I put on 70-75 pounds in less than 2 years. My skin has become so dark on my face in certain spots that it has become impossible to find a makeup that actually works, also it has become very oily, and I experience bad acne. I now have high blood pressure and had 2 be put on a medication to help kinda control it. My depression and anxiety has become so severe that I have been near suicide, and have been put on 2 different anti-anxiety/depression meds and still I have irrational thoughts and depression. The first couple months after I got on the shot I experienced extreme vaginal itching, and have not had a period since Christmas '09. I'm very bloated EVERYWHERE, I experience hot flashes that r OUT of this world, and sometimes night sweats.My neck, back and legs are in extreme pain almost ALL of the time.My belly has become so large that it actually looks like i'm in the third trimester of pregnancy and my breast have also become very enlarged and painful I had 3 pregnancy tests and 2 ultra sounds because of suspition that I may be pregnant because of the massive belly weight they were all negative,I can't walk up the stairs without getting short of breath or even put on my shoes and breathe at the same time because of the massive weight in my belly.My hair sheds tremendously and has become very thin, I get migrains at least twice a week now.This drug is VERY dangerous!! I wouldn't reccomend it to ANYbody!! F 27 2 years
1X O
1/16/2011
 1  Birth Control Weight gain,bloating,IBS symptoms worsened,headaches,muscle aches, hot flashes, mood swings. I decided to go on Depo because I thought it was a sure way to never forget to take a pill. I was warned about the possible weight gain but not the other horrible side effects. I got a total of three shots (So i was on Depo for about a year) I decided to go off depo only because I am not sexually active and didn't feel the need for one. Well I received my last shot in August 2010 and was due for one in November 2010. I had a month long period in October which was pretty terrible but not as bad as the withdrawal symptoms I started to feel just a few weeks after missing my next scheduled shot. I felt anxious and nervous all the time I was having mood swings and started to feel depressed. My life isn't perfect and I am under a great deal of stress all the time so at first I felt that school and life was just stressing me out. Well on horrible night in December I had the worse panic attack in my life and it sent me to the ER. I have made several trips to the ER since but they just told me I was stressed. I have seen my doctor but they don't believe I am having withdrawal symptoms. REALLY? Well I guess they should visit all of the sites with unhappy patients who go on and on about how horrible they felt going off depo. I have seen a Therapist and they all just think I am depressed. Well trust me I have been depressed be for and this is so much different and much worse. I can't wait until this crap has left my body because I feel horrible. I will go from feeling fine and happy and F 24 1 years
1X O
1/8/2011
 1  Contraception I gained weight and got spotty. At first I didn't attribute the weight gain to the depo, but then since coming off the depo (last march was my last shot) I've gradually lost some of the weight I gained (not all of it though). Since coming off the depo, I've felt like crap! For a couple of months I couldn't keep anything down - was violently sick pretty much every time I ate; SEVERE constipation; feeling like I had period cramps nearly all of the time. I've got such bad vaginal dryness now, that the skin at the top keeps splitting, and no matter how much lubrication we use I nearly always tear during sex. I got my first period after stopping the depo on 30th November (my last depo if I'd had it was meant to be June) next one three weeks and one day later on 22nd December, now two weeks and one day later I've come on again. I was so excited when my period came back, because we want a baby, but now I'm not sure if I am ovulating properly or not. When I first discussed the dep This drug should be banned. F 29 3 years
??? 1X O
1/6/2011
Email
 5  Aniemia a wierd feeling under my sternum. I have had some spotting and am always tired. i get very hungry every once and a while. i just started the depo shot. I have however used a generic one in the past and it works just as well. For my aniemia this is the best thing to use. F 30 14 days
1X O
1/4/2011
 4  Birth Control Little to no side effects. I was EXTREMELY hungry for the first month because I had done a little research after taking the shot and was super paranoid about gaining weight because I am only 110lbs to begin with. I am 2/3 into my first shot and just beginning to be on the irritable side. I was on Seasonale for two years and started experiencing migraines every second day so my doctor advised me to go off, I took a month with no birth control then went on Lo-Estrin. Lo-Estrin did not work for me at all. It took the migraines away but I gained weight and then bled through the whole time. I could not handle being irregular so I made a rash decision one morning and called my doctor to get the shot. The week after I had the shot I started to research it on the internet and came across hundreds of bad reviews of girls saying never to get the shot, that it was the biggest mistake they could have made. Girls saying they gained 5-50lbs. that was not acceptable for me! Since I was paranoid about gaining weight I was watching what I was eating but VERY hungry. Being conscious of eating did not last long and I quickly forgot about the stories I read online. Looking back now I don’t believe I have gained anything (not including the 3 turkey dinners this holiday season) I would recommend depo, I am yet to have any spotting, no migraines, no gaining, no hair loss I guess I will see in the next couple months after my second shot if I am still satisfied but I cannot complain! F 20 2 months
1X O
1/4/2011
Email
 1  assure my mom no prenancy soon. Small dent in my upper right arm... Stomach issues.. wieght gain... etc. I started DEPO when i was 15, now im 17. At first i loved it, i had nothing to remember! I barely had any side affects the first time i took it, honestly the only reason i got off was because i was too scared to get a PAP smear. With in six months i returned to depo because of a boyfriend. I still didn't notice many side affects, but i also wasn't aware of most of them! A gained some weight, and still haven't been able to lose it! I don't look overweight but it truly bothers me i cant break away from this weight gain! ANother was my period! I had a brown period, can anyone say nasty! I asked my doctor why, they said that's cause it old blood! I replied, i thought your blood didn't build up when your on depo, how can it be old? He didn't know. I couldnt break away from this! my stomach, when i would eat anything for nearly a year i would get horrible sick and couldn't go places, still kept on the weight threw that! I eventually had to deal with getting sick everywhere i went, which was very frustrating at 16! Right after my last shot i notice a small indention in my upper right arm when they would poke me with the needle.. Now that im off it i figured it would go away. I was wrong, it gotten so much worse, i have a serious indent in my arm, completely visible! People ask me what i did to do that, i showed my nurse and she nearly shit her pants she didn't have any idea! I dont either but its disgusting, its a hole under my skin where the muscle has moved apart, separated its se F 17 18 months
30 MG 1X AN
1/4/2011
 4  no pregnancy and no periods ive had my shot for about 3 weeks now and im jst now getting side effects. Ive bloated a little, have some abdominal cramps at night time, i also get nauseous, and have hot flashes. My period stopped immediately which i loved! And my sex drive has increased alot so the decrease dsnt always happen it jst depends on the person. Everything ive had is something i can deal with. My body hurts on certain days all over but its mostly when i havent really gotten up and done anything. I have back pain but thts normal for me because of the activites i do at school. Other than these i think tht its great :) F 15
50 1X O
12/29/2010
 1  Stop period, have unprotected sex Decreased appetite, nausea, lightheadedness, persistent headaches, bloating, abdominal pain and cramps, depression, anxiety, past suicidal thoughts, constant fatigue, excessive hair growth on face, bladder pressure, frequent urination and large amounts of urine disposed, additionally possibly contributed to yeast infection. My doctor told me symptoms were mild and I could possibly gain 3-5 pounds. She was wrong. I really wish I had asked more persistently about other side effects. I wish I had listened to my instincts and not have gotten the shot. I may have to live with these symptoms for weeks or months. I feel extremely discouraged and depressed, and I'm trying my best to be optimistic and lead my life as I did before. I do not want to gain weight as I am a heavy exerciser. This shot is life transforming. Unfortunately it's not helpful in my life and I strongly recommend not injecting one's body with powerful hormones. The Depo shot is like playing Russian Roulette. Please don't go for convenience, take something that can be neutralized or will exit the body shortly in case anything negative happens to you. I didn't think this would happen to me...and I'm sorry I was naive and blindsighted. F 18 2 weeks
Not sure 1X O
12/29/2010
 3  Easier method Massive weight gain, depression, mood swings, hormone imbalance I thought this was the easiest way to keep from getting pregnant and the thought of my period going away sweetened the deal, 3 years later and still using i've gained almost 25 pounds and so sad about it :[ F 19
1X O
12/27/2010
 1  birth control fast weight gain, Bloating (which led to the feeling of unhappiness and discomfort). After 2+ months of taking it I decided that It would be my last and instead use other birth control methods. The Bloating and the really quick weight gain made me very unhappy and worry about my look. I am petite size person but within 2+ months I moved 2 sizes up. I am not pregnant but wear maternity clothes! I was not advised about the appetite increase and the bloating. I am thankful that I God willing in 2 weeks I will be freed from the depo and its ill effects. I had no mood swings or any type of depression and had no period and no spotting so far. I would advice those who decide to take the depo shot to mind their eating habits and be a gym member. But if you can use other birth control then avoid the depo. F 35 3 months
1X O
12/27/2010
 1  Birth Control This drug is dangerous and has made my life literally, a living hell for the past couple months! I have severe anxiety attacks that occur almost daily. I have shortness of breath, massive headaches, fatiqued, hot sweats.. etc. I had a severe panic attack the other day and had to go to the emergency room. I cannot leave my home because I get dizzy and feel like I am going to pass out. I know feel this way in my own home. I am a prisoner in my own home because of this aweful drug! Two more months and hopefully this drug will be out of my system so I can go back to living a normal life again! F 25
1X AN
12/25/2010
 1  Contraceptive Severe acne, moodiness, nervousness, bloating, food cravings, weight gain, hair loss, joint pain, depression. I started taking this shot around Oct 2009. The first 2 shots were heaven. I noticed some hot flashes, but they went away as my body got used to the hormones. Then, during the last 6 months, I developed severe acne and hair loss. The whole time I've been on the shot, I've been nervous, depressed and have crazy food cravings (which has caused me to gain weight. I can't seem to lose it either...and I run marathons.) I am also very tired and experience joint pain. I've also noticed a lot of hair in the drain. Also, after I would get the shot, I would feel super sick. Like I had the flu and my period at the same time. I would cramp AND have body aches, I would be hot and cold at the same time, have pain at the injection site, have headaches, crave food, be bloated...My next injection is supposed to be in a week, but I am not going back. DO NOT RECOMMENDED F 19 1 years
1 shot 1X O
12/24/2010
 1  Endometriosis Weight gain 30 lbs. Hyper tension. Severe acne. Mood swings. Fatigue. Sweating alot. Bloating. I am 18 years old and was 130 lbs since I was 13 years old. I always had a very balanced diet and when I went on this medication I experienced extreme hunger. I exercised as much as I could until I noticed that my chest began to hurt. I remember it was May and I had prom in June and I was freaking out because I had acne all over my back and face. I never had acne before this medication. I called my doctor and I was told that it was a dermatologists problem. So now it's August and I went to my doctor to get another shot. I got weighed and gained 30 lbs in under a year even with exercise. I spoke to my doctor and asked her why did I gain weight and why was I covered in acne? At this point in time the acne was down to my wrists, on my thighs, chest, back, lower back, neck, scalp, and it was going onto my stomach. Now I am off the shot and dealing with acne, stretch marks (even though I lost weight), and depression. If you notice acne or any side effect if that, please get off this medication. I can't wear t-shirts or shorts even though I lost weight because of the severe acne. People ask me if I have hives or singles. To be perfectly honest I rather not take any pills at all and live with the consequences of my disease. At least I was still me and not some ugly monster that I am now just because that doctor didn't want to operate or refer me to a more experienced surgeon who could've gotten rid of the disease for good. F 18 1 years
1X O
12/21/2010
 5  endometriosis I am a little moody and have had a little vaginal dryness, The 1st couple of days after the shot, I have mild headaches, but they go away. It has been a blessing so far. No periods since I started, so no cramps! It affects everyone differently. I feel bad for the women who have had such a terrible time on it. For me it is wonderful. My doc told me when I started that it is an appetite stimulant so I needed to be careful and monitor what I ate. I did this and found that I was able to control cravings and I have lost 8 pounds, so weight gain is not a definite side effect. Don't be scared off! After reading some of the negative experiences, I almost was. Individual people have individual side effects. F 36 4 months
1X AN
12/19/2010

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